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Items: 1 to 50 of 144

1.

HO-1 downregulation favors BRAFV600 melanoma cell death induced by Vemurafenib/PLX4032 and increases NK recognition.

Furfaro AL, Ottonello S, Loi G, Cossu I, Piras S, Spagnolo F, Queirolo P, Marinari UM, Moretta L, Pronzato MA, Mingari MC, Pietra G, Nitti M.

Int J Cancer. 2019 Aug 3. doi: 10.1002/ijc.32611. [Epub ahead of print]

PMID:
31376303
2.

Heme Oxygenase 1 in the Nervous System: Does It Favor Neuronal Cell Survival or Induce Neurodegeneration?

Nitti M, Piras S, Brondolo L, Marinari UM, Pronzato MA, Furfaro AL.

Int J Mol Sci. 2018 Aug 1;19(8). pii: E2260. doi: 10.3390/ijms19082260. Review.

3.

microRNA-494 Favors HO-1 Expression in Neuroblastoma Cells Exposed to Oxidative Stress in a Bach1-Independent Way.

Piras S, Furfaro AL, Caggiano R, Brondolo L, Garibaldi S, Ivaldo C, Marinari UM, Pronzato MA, Faraonio R, Nitti M.

Front Oncol. 2018 Jun 13;8:199. doi: 10.3389/fonc.2018.00199. eCollection 2018.

4.

Matrine in association with FD‑2 stimulates F508del‑cystic fibrosis transmembrane conductance regulator activity in the presence of corrector VX809.

Marengo B, Speciale A, Senatore L, Garibaldi S, Musumeci F, Nieddu E, Pollarolo B, Pronzato MA, Schenone S, Mazzei M, Domenicotti C.

Mol Med Rep. 2017 Dec;16(6):8849-8853. doi: 10.3892/mmr.2017.7736. Epub 2017 Oct 6.

5.

Differentiation impairs Bach1 dependent HO-1 activation and increases sensitivity to oxidative stress in SH-SY5Y neuroblastoma cells.

Piras S, Furfaro AL, Brondolo L, Passalacqua M, Marinari UM, Pronzato MA, Nitti M.

Sci Rep. 2017 Aug 8;7(1):7568. doi: 10.1038/s41598-017-08095-7.

6.

Investigating the amyloid-beta enhancing effect of cGMP in neuro2a cells.

Calcagno E, Caudano F, Passalacqua M, Pronzato MA, Fedele E, Ricciarelli R.

Mech Ageing Dev. 2017 Sep;166:1-5. doi: 10.1016/j.mad.2017.08.001. Epub 2017 Aug 5.

PMID:
28789837
7.

Amyloid-β Peptide Is Needed for cGMP-Induced Long-Term Potentiation and Memory.

Palmeri A, Ricciarelli R, Gulisano W, Rivera D, Rebosio C, Calcagno E, Tropea MR, Conti S, Das U, Roy S, Pronzato MA, Arancio O, Fedele E, Puzzo D.

J Neurosci. 2017 Jul 19;37(29):6926-6937. doi: 10.1523/JNEUROSCI.3607-16.2017. Epub 2017 Jun 16.

8.

HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation.

Nitti M, Piras S, Marinari UM, Moretta L, Pronzato MA, Furfaro AL.

Antioxidants (Basel). 2017 May 5;6(2). pii: E29. doi: 10.3390/antiox6020029. Review.

9.

Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease.

Ricciarelli R, Brullo C, Prickaerts J, Arancio O, Villa C, Rebosio C, Calcagno E, Balbi M, van Hagen BT, Argyrousi EK, Zhang H, Pronzato MA, Bruno O, Fedele E.

Sci Rep. 2017 Apr 12;7:46320. doi: 10.1038/srep46320.

10.

Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma.

Colla R, Izzotti A, De Ciucis C, Fenoglio D, Ravera S, Speciale A, Ricciarelli R, Furfaro AL, Pulliero A, Passalacqua M, Traverso N, Pronzato MA, Domenicotti C, Marengo B.

Oncotarget. 2016 Oct 25;7(43):70715-70737. doi: 10.18632/oncotarget.12209.

11.

Vitamins D3 and K2 may partially counterbalance the detrimental effects of pentosidine in ex vivo human osteoblasts.

Sanguineti R, Monacelli F, Parodi A, Furfaro AL, Borghi R, Pacini D, Pronzato MA, Odetti P, Molfetta L, Traverso N.

J Biol Regul Homeost Agents. 2016 Jul-Sep;30(3):713-726.

PMID:
27655488
12.

New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment.

Brullo C, Ricciarelli R, Prickaerts J, Arancio O, Massa M, Rotolo C, Romussi A, Rebosio C, Marengo B, Pronzato MA, van Hagen BTJ, van Goethem NP, D'Ursi P, Orro A, Milanesi L, Guariento S, Cichero E, Fossa P, Fedele E, Bruno O.

Eur J Med Chem. 2016 Nov 29;124:82-102. doi: 10.1016/j.ejmech.2016.08.018. Epub 2016 Aug 13.

PMID:
27560284
13.

Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy.

Marengo B, Nitti M, Furfaro AL, Colla R, Ciucis CD, Marinari UM, Pronzato MA, Traverso N, Domenicotti C.

Oxid Med Cell Longev. 2016;2016:6235641. doi: 10.1155/2016/6235641. Epub 2016 Jun 21. Review.

14.

RAGE Expression and ROS Generation in Neurons: Differentiation versus Damage.

Piras S, Furfaro AL, Domenicotti C, Traverso N, Marinari UM, Pronzato MA, Nitti M.

Oxid Med Cell Longev. 2016;2016:9348651. doi: 10.1155/2016/9348651. Epub 2016 May 25. Review.

15.

Role of Nrf2, HO-1 and GSH in Neuroblastoma Cell Resistance to Bortezomib.

Furfaro AL, Piras S, Domenicotti C, Fenoglio D, De Luigi A, Salmona M, Moretta L, Marinari UM, Pronzato MA, Traverso N, Nitti M.

PLoS One. 2016 Mar 29;11(3):e0152465. doi: 10.1371/journal.pone.0152465. eCollection 2016.

16.

The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance.

Furfaro AL, Traverso N, Domenicotti C, Piras S, Moretta L, Marinari UM, Pronzato MA, Nitti M.

Oxid Med Cell Longev. 2016;2016:1958174. doi: 10.1155/2016/1958174. Epub 2015 Nov 30. Review.

17.

Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages.

Marengo B, Bellora F, Ricciarelli R, De Ciucis C, Furfaro A, Leardi R, Colla R, Pacini D, Traverso N, Moretta A, Pronzato MA, Bottino C, Domenicotti C.

Biofactors. 2016 Jan-Feb;42(1):80-92. doi: 10.1002/biof.1243. Epub 2015 Dec 16.

PMID:
26669587
18.

Heme oxygenase-1-derived bilirubin protects endothelial cells against high glucose-induced damage.

He M, Nitti M, Piras S, Furfaro AL, Traverso N, Pronzato MA, Mann GE.

Free Radic Biol Med. 2015 Dec;89:91-8. doi: 10.1016/j.freeradbiomed.2015.07.151. Epub 2015 Sep 21.

PMID:
26391462
19.

Amyloid β: Walking on the dark side of the moon.

Fedele E, Rivera D, Marengo B, Pronzato MA, Ricciarelli R.

Mech Ageing Dev. 2015 Dec;152:1-4. doi: 10.1016/j.mad.2015.09.001. Epub 2015 Sep 8. Review.

PMID:
26362724
20.

Synthesis, biological activities and pharmacokinetic properties of new fluorinated derivatives of selective PDE4D inhibitors.

Brullo C, Massa M, Villa C, Ricciarelli R, Rivera D, Pronzato MA, Fedele E, Barocelli E, Bertoni S, Flammini L, Bruno O.

Bioorg Med Chem. 2015 Jul 1;23(13):3426-35. doi: 10.1016/j.bmc.2015.04.027. Epub 2015 Apr 16.

PMID:
25936260
21.

Evaluating the role of hnRNP-C and FMRP in the cAMP-induced APP metabolism.

Rivera D, Fedele E, Marinari UM, Pronzato MA, Ricciarelli R.

Biofactors. 2015 Mar-Apr;41(2):121-6. doi: 10.1002/biof.1207. Epub 2015 Mar 23.

PMID:
25809670
22.

N-alkyl carbazole derivatives as new tools for Alzheimer's disease: preliminary studies.

Saturnino C, Iacopetta D, Sinicropi MS, Rosano C, Caruso A, Caporale A, Marra N, Marengo B, Pronzato MA, Parisi OI, Longo P, Ricciarelli R.

Molecules. 2014 Jul 2;19(7):9307-17. doi: 10.3390/molecules19079307.

23.

A novel mechanism for cyclic adenosine monophosphate-mediated memory formation: Role of amyloid beta.

Ricciarelli R, Puzzo D, Bruno O, Canepa E, Gardella E, Rivera D, Privitera L, Domenicotti C, Marengo B, Marinari UM, Palmeri A, Pronzato MA, Arancio O, Fedele E.

Ann Neurol. 2014 Apr;75(4):602-7. doi: 10.1002/ana.24130. Epub 2014 Apr 14.

PMID:
24591104
24.
25.

Monomeric Aβ1-42 and RAGE: key players in neuronal differentiation.

Piras S, Furfaro AL, Piccini A, Passalacqua M, Borghi R, Carminati E, Parodi A, Colombo L, Salmona M, Pronzato MA, Marinari UM, Tabaton M, Nitti M.

Neurobiol Aging. 2014 Jun;35(6):1301-8. doi: 10.1016/j.neurobiolaging.2014.01.002. Epub 2014 Jan 10.

PMID:
24484607
26.

HO-1 up-regulation: a key point in high-risk neuroblastoma resistance to bortezomib.

Furfaro AL, Piras S, Passalacqua M, Domenicotti C, Parodi A, Fenoglio D, Pronzato MA, Marinari UM, Moretta L, Traverso N, Nitti M.

Biochim Biophys Acta. 2014 Apr;1842(4):613-22. doi: 10.1016/j.bbadis.2013.12.008. Epub 2013 Dec 28.

27.

Role of glutathione in cancer progression and chemoresistance.

Traverso N, Ricciarelli R, Nitti M, Marengo B, Furfaro AL, Pronzato MA, Marinari UM, Domenicotti C.

Oxid Med Cell Longev. 2013;2013:972913. doi: 10.1155/2013/972913. Epub 2013 May 20. Review.

28.

Structural alterations of human serum albumin caused by glycative and oxidative stressors revealed by circular dichroism analysis.

Monacelli F, Storace D, D'Arrigo C, Sanguineti R, Borghi R, Pacini D, Furfaro AL, Pronzato MA, Odetti P, Traverso N.

Int J Mol Sci. 2013 May 23;14(6):10694-709. doi: 10.3390/ijms140610694.

29.

p38MAPK inhibition: a new combined approach to reduce neuroblastoma resistance under etoposide treatment.

Marengo B, De Ciucis CG, Ricciarelli R, Furfaro AL, Colla R, Canepa E, Traverso N, Marinari UM, Pronzato MA, Domenicotti C.

Cell Death Dis. 2013 Apr 11;4:e589. doi: 10.1038/cddis.2013.118.

30.

Cyclic adenosine monophosphate as an endogenous modulator of the amyloid-β precursor protein metabolism.

Canepa E, Domenicotti C, Marengo B, Passalacqua M, Marinari UM, Pronzato MA, Fedele E, Ricciarelli R.

IUBMB Life. 2013 Feb;65(2):127-33. doi: 10.1002/iub.1109. Epub 2013 Jan 8.

31.

Cholesterol and Alzheimer's disease: a still poorly understood correlation.

Ricciarelli R, Canepa E, Marengo B, Marinari UM, Poli G, Pronzato MA, Domenicotti C.

IUBMB Life. 2012 Dec;64(12):931-5. doi: 10.1002/iub.1091. Epub 2012 Nov 2. Review.

32.

Metalloproteinases and advanced glycation end products: coupled navigation in atherosclerotic plaque pathophysiology?

Furfaro AL, Sanguineti R, Storace D, Monacelli F, Puzzo A, Pronzato MA, Odetti P, Traverso N.

Exp Clin Endocrinol Diabetes. 2012 Nov;120(10):586-90. doi: 10.1055/s-0032-1323739. Epub 2012 Oct 16.

PMID:
23073918
33.

Short exposure of albumin to high concentrations of malondialdehyde does not mimic physiological conditions.

Millanta S, Furfaro AL, Carlier P, Tasso B, Nitti M, Domenicotti C, Odetti P, Pronzato MA, Traverso N.

Exp Mol Pathol. 2013 Feb;94(1):270-6. doi: 10.1016/j.yexmp.2012.06.008. Epub 2012 Jul 4.

PMID:
22771309
34.

Impaired synthesis contributes to diabetes-induced decrease in liver glutathione.

Furfaro AL, Nitti M, Marengo B, Domenicotti C, Cottalasso D, Marinari UM, Pronzato MA, Traverso N.

Int J Mol Med. 2012 May;29(5):899-905. doi: 10.3892/ijmm.2012.915. Epub 2012 Feb 14.

PMID:
22344537
35.

Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1.

Furfaro AL, Macay JR, Marengo B, Nitti M, Parodi A, Fenoglio D, Marinari UM, Pronzato MA, Domenicotti C, Traverso N.

Free Radic Biol Med. 2012 Jan 15;52(2):488-96. doi: 10.1016/j.freeradbiomed.2011.11.007. Epub 2011 Nov 13.

PMID:
22142473
36.

GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses.

Bruno O, Fedele E, Prickaerts J, Parker LA, Canepa E, Brullo C, Cavallero A, Gardella E, Balbi A, Domenicotti C, Bollen E, Gijselaers HJ, Vanmierlo T, Erb K, Limebeer CL, Argellati F, Marinari UM, Pronzato MA, Ricciarelli R.

Br J Pharmacol. 2011 Dec;164(8):2054-63. doi: 10.1111/j.1476-5381.2011.01524.x.

37.

Cholesterol and amyloid-β: evidence for a cross-talk between astrocytes and neuronal cells.

Canepa E, Borghi R, Viña J, Traverso N, Gambini J, Domenicotti C, Marinari UM, Poli G, Pronzato MA, Ricciarelli R.

J Alzheimers Dis. 2011;25(4):645-53. doi: 10.3233/JAD-2011-110053.

PMID:
21483097
38.

PKCδ sensitizes neuroblastoma cells to L-buthionine-sulfoximine and etoposide inducing reactive oxygen species overproduction and DNA damage.

Marengo B, De Ciucis C, Ricciarelli R, Passalacqua M, Nitti M, Zingg JM, Marinari UM, Pronzato MA, Domenicotti C.

PLoS One. 2011 Feb 7;6(2):e14661. doi: 10.1371/journal.pone.0014661.

39.

Protein kinase C: an attractive target for cancer therapy.

Marengo B, De Ciucis C, Ricciarelli R, Pronzato MA, Marinari UM, Domenicotti C.

Cancers (Basel). 2011 Feb 1;3(1):531-67. doi: 10.3390/cancers3010531.

40.

Human mesangial cells resist glycoxidative stress through an antioxidant response.

Nitti M, Furfaro AL, Patriarca S, Balbis E, Domenicotti C, Cottalasso D, Pronzato MA, Marinari UM, Traverso N.

Int J Mol Med. 2011 Feb;27(2):213-9. doi: 10.3892/ijmm.2010.576. Epub 2010 Dec 6.

PMID:
21152865
41.

DNA oxidative damage of neoplastic rat liver lesions.

Marengo B, De Ciusis C, Ricciarelli R, Romano P, Passalacqua M, Marinari UM, Pronzato MA, Domenicotti C.

Oncol Rep. 2010 May;23(5):1241-6.

PMID:
20372836
42.

PKC delta and NADPH oxidase in retinoic acid-induced neuroblastoma cell differentiation.

Nitti M, Furfaro AL, Cevasco C, Traverso N, Marinari UM, Pronzato MA, Domenicotti C.

Cell Signal. 2010 May;22(5):828-35. doi: 10.1016/j.cellsig.2010.01.007. Epub 2010 Jan 13.

PMID:
20074641
43.

A comparative study of leukaemia inhibitory factor and interleukin-1alpha intracellular content in a human keratinocyte cell line after exposure to cosmetic fragrances and sodium dodecyl sulphate.

Parodi A, Sanguineti R, Catalano M, Penco S, Pronzato MA, Scanarotti C, Bassi AM.

Toxicol Lett. 2010 Feb 1;192(2):101-7. doi: 10.1016/j.toxlet.2009.10.013. Epub 2009 Oct 28.

PMID:
19878710
44.

Whey proteins influence hepatic glutathione after CCl4 intoxication.

Balbis E, Patriarca S, Furfaro AL, Millanta S, Sukkar SG, Marinari UM, Pronzato MA, Cottalasso D, Traverso N.

Toxicol Ind Health. 2009 May-Jun;25(4-5):325-8. doi: 10.1177/0748233709104870.

PMID:
19651804
45.

Protein kinase C-dependent alpha-secretory processing of the amyloid precursor protein is mediated by phosphorylation of myosin II-B.

Argellati F, Domenicotti C, Passalacqua M, Janda E, Melloni E, Marinari UM, Pronzato MA, Ricciarelli R.

FASEB J. 2009 Apr;23(4):1246-51. doi: 10.1096/fj.08-119263. Epub 2008 Dec 22.

PMID:
19103644
46.

GSH loss per se does not affect neuroblastoma survival and is not genotoxic.

Marengo B, Balbis E, Patriarca S, De Ciucis C, Furfaro A, Nitti M, Marinari UM, Pronzato MA, Traverso N, Domenicotti C.

Int J Oncol. 2008 Jan;32(1):121-7.

PMID:
18097550
47.

PKC signaling in oxidative hepatic damage.

Nitti M, Pronzato MA, Marinari UM, Domenicotti C.

Mol Aspects Med. 2008 Feb-Apr;29(1-2):36-42. Epub 2007 Oct 7. Review.

PMID:
18035409
48.

Mechanisms of BSO (L-buthionine-S,R-sulfoximine)-induced cytotoxic effects in neuroblastoma.

Marengo B, De Ciucis C, Verzola D, Pistoia V, Raffaghello L, Patriarca S, Balbis E, Traverso N, Cottalasso D, Pronzato MA, Marinari UM, Domenicotti C.

Free Radic Biol Med. 2008 Feb 1;44(3):474-82. Epub 2007 Oct 22.

PMID:
17991446
49.

In vitro effect of PPAR-gamma2 Pro12Ala polymorphism on the deposition of Alzheimer's amyloid-beta peptides.

d'Abramo C, Zingg JM, Pizzuti A, Argellati F, Pronzato MA, Ricciarelli R.

Brain Res. 2007 Oct 10;1173:1-5. Epub 2007 Aug 9.

PMID:
17803977
50.

Downregulation of myosin II-B by siRNA alters the subcellular localization of the amyloid precursor protein and increases amyloid-beta deposition in N2a cells.

Massone S, Argellati F, Passalacqua M, Armirotti A, Melone L, d'Abramo C, Marinari UM, Domenicotti C, Pronzato MA, Ricciarelli R.

Biochem Biophys Res Commun. 2007 Oct 26;362(3):633-8. Epub 2007 Aug 21.

PMID:
17727819

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