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Items: 1 to 50 of 99

1.

Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast.

Beaupere C, Dinatto L, Wasko BM, Chen RB, VanValkenburg L, Kiflezghi MG, Lee MB, Promislow DEL, Dang W, Kaeberlein M, Labunskyy VM.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9586-9591. doi: 10.1073/pnas.1804264115. Epub 2018 Sep 5.

PMID:
30185560
2.

Canine hyperadrenocorticism associations with signalment, selected comorbidities and mortality within North American veterinary teaching hospitals.

Hoffman JM, Lourenço BN, Promislow DEL, Creevy KE.

J Small Anim Pract. 2018 Jul 23. doi: 10.1111/jsap.12904. [Epub ahead of print]

PMID:
30039567
3.

The Effects of Graded Levels of Calorie Restriction: XIII. Global Metabolomics Screen Reveals Graded Changes in Circulating Amino Acids, Vitamins, and Bile Acids in the Plasma of C57BL/6 Mice.

Green CL, Soltow QA, Mitchell SE, Derous D, Wang Y, Chen L, Han JJ, Promislow DEL, Lusseau D, Douglas A, Jones DP, Speakman JR.

J Gerontol A Biol Sci Med Sci. 2018 Apr 30. doi: 10.1093/gerona/gly058. [Epub ahead of print]

PMID:
29718123
4.

The companion dog as a model for human aging and mortality.

Hoffman JM, Creevy KE, Franks A, O'Neill DG, Promislow DEL.

Aging Cell. 2018 Jun;17(3):e12737. doi: 10.1111/acel.12737. Epub 2018 Feb 19.

5.

All's well that ends well: why large species have short telomeres.

Risques RA, Promislow DEL.

Philos Trans R Soc Lond B Biol Sci. 2018 Mar 5;373(1741). pii: 20160448. doi: 10.1098/rstb.2016.0448.

PMID:
29335372
6.

Recent Advances in the Systems Biology of Aging.

McCormick MA, Promislow DEL.

Antioxid Redox Signal. 2018 Oct 1;29(10):973-984. doi: 10.1089/ars.2017.7367. Epub 2017 Nov 20.

PMID:
29020802
7.

Tissue-specific insulin signaling mediates female sexual attractiveness.

Fedina TY, Arbuthnott D, Rundle HD, Promislow DEL, Pletcher SD.

PLoS Genet. 2017 Aug 17;13(8):e1006935. doi: 10.1371/journal.pgen.1006935. eCollection 2017 Aug.

8.

Perceptive costs of reproduction drive ageing and physiology in male Drosophila.

Harvanek ZM, Lyu Y, Gendron CM, Johnson JC, Kondo S, Promislow DEL, Pletcher SD.

Nat Ecol Evol. 2017 May 15;1(6):152. doi: 10.1038/s41559-017-0152.

9.

The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome.

Derous D, Mitchell SE, Wang L, Green CL, Wang Y, Chen L, Han JJ, Promislow DEL, Lusseau D, Douglas A, Speakman JR.

Aging (Albany NY). 2017 Jul 31;9(7):1770-1824. doi: 10.18632/aging.101269.

10.

Proteomics and metabolomics in ageing research: from biomarkers to systems biology.

Hoffman JM, Lyu Y, Pletcher SD, Promislow DEL.

Essays Biochem. 2017 Jul 11;61(3):379-388. doi: 10.1042/EBC20160083. Print 2017 Jul 15. Review.

11.

The Effects of Graded Levels of Calorie Restriction: X. Transcriptomic Responses of Epididymal Adipose Tissue.

Derous D, Mitchell SE, Green CL, Wang Y, Han JDJ, Chen L, Promislow DEL, Lusseau D, Douglas A, Speakman JR.

J Gerontol A Biol Sci Med Sci. 2018 Mar 2;73(3):279-288. doi: 10.1093/gerona/glx101.

12.

A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs.

Urfer SR, Kaeberlein TL, Mailheau S, Bergman PJ, Creevy KE, Promislow DEL, Kaeberlein M.

Geroscience. 2017 Apr;39(2):117-127. doi: 10.1007/s11357-017-9972-z. Epub 2017 Apr 3.

13.

Asymptomatic heart valve dysfunction in healthy middle-aged companion dogs and its implications for cardiac aging.

Urfer SR, Kaeberlein TL, Mailheau S, Bergman PJ, Creevy KE, Promislow DE, Kaeberlein M.

Geroscience. 2017 Feb;39(1):43-50. doi: 10.1007/s11357-016-9956-4. Epub 2017 Jan 14.

14.

The effects of graded levels of calorie restriction: VIII. Impact of short term calorie and protein restriction on basal metabolic rate in the C57BL/6 mouse.

Mitchell SE, Tang Z, Kerbois C, Delville C, Derous D, Green CL, Wang Y, Han JJ, Chen L, Douglas A, Lusseau D, Promislow DE, Speakman JR.

Oncotarget. 2017 Mar 14;8(11):17453-17474. doi: 10.18632/oncotarget.15294.

15.

The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice.

Green CL, Mitchell SE, Derous D, Wang Y, Chen L, Han JJ, Promislow DEL, Lusseau D, Douglas A, Speakman JR.

Aging Cell. 2017 Jun;16(3):529-540. doi: 10.1111/acel.12570. Epub 2017 Jan 31.

16.

Mate choice in fruit flies is rational and adaptive.

Arbuthnott D, Fedina TY, Pletcher SD, Promislow DE.

Nat Commun. 2017 Jan 17;8:13953. doi: 10.1038/ncomms13953.

17.

Multiple morbidities in companion dogs: a novel model for investigating age-related disease.

Jin K, Hoffman JM, Creevy KE, O'Neill DG, Promislow DE.

Pathobiol Aging Age Relat Dis. 2016 Nov 21;6:33276. doi: 10.3402/pba.v6.33276. eCollection 2016.

18.

Answering evolutionary questions: A guide for mechanistic biologists.

Masel J, Promislow DE.

Bioessays. 2016 Jul;38(7):704-11. doi: 10.1002/bies.201600029. Epub 2016 May 6. Review.

19.

The dog aging project: translational geroscience in companion animals.

Kaeberlein M, Creevy KE, Promislow DE.

Mamm Genome. 2016 Aug;27(7-8):279-88. doi: 10.1007/s00335-016-9638-7. Epub 2016 May 3. Review.

20.

The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks.

Derous D, Mitchell SE, Green CL, Wang Y, Han JD, Chen L, Promislow DE, Lusseau D, Speakman JR, Douglas A.

Aging (Albany NY). 2016 May;8(5):917-32. doi: 10.18632/aging.100944.

21.

Plasma Metabolomics of Common Marmosets (Callithrix jacchus) to Evaluate Diet and Feeding Husbandry.

Banton SA, Soltow QA, Liu KH, Uppal K, Promislow DE, Power ML, Tardif SD, Wachtman LM, Jones DP.

J Am Assoc Lab Anim Sci. 2016 Mar;55(2):137-46.

22.

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse.

Mitchell SE, Delville C, Konstantopedos P, Derous D, Green CL, Wang Y, Han JD, Promislow DE, Douglas A, Chen L, Lusseau D, Speakman JR.

Oncotarget. 2016 Apr 12;7(15):19147-70. doi: 10.18632/oncotarget.8158.

23.

The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways.

Derous D, Mitchell SE, Green CL, Chen L, Han JD, Wang Y, Promislow DE, Lusseau D, Speakman JR, Douglas A.

Aging (Albany NY). 2016 Apr;8(4):642-63. doi: 10.18632/aging.100895.

24.

A longitudinal analysis of the effects of age on the blood plasma metabolome in the common marmoset, Callithrix jacchus.

Hoffman JM, Tran V, Wachtman LM, Green CL, Jones DP, Promislow DE.

Exp Gerontol. 2016 Apr;76:17-24. doi: 10.1016/j.exger.2016.01.007. Epub 2016 Jan 21.

25.

Correction: Metabolic Characterization of the Common Marmoset (Callithrix jacchus).

Go YM, Liang Y, Uppal K, Soltow QA, Promislow DE, Wachtman LM, Jones DP.

PLoS One. 2016 Jan 22;11(1):e0147880. doi: 10.1371/journal.pone.0147880. eCollection 2016. No abstract available.

26.

The Companion Dog as a Model for the Longevity Dividend.

Creevy KE, Austad SN, Hoffman JM, O'Neill DG, Promislow DE.

Cold Spring Harb Perspect Med. 2016 Jan 4;6(1):a026633. doi: 10.1101/cshperspect.a026633. Review.

27.

Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.

Furlan SN, Watkins B, Tkachev V, Flynn R, Cooley S, Ramakrishnan S, Singh K, Giver C, Hamby K, Stempora L, Garrett A, Chen J, Betz KM, Ziegler CG, Tharp GK, Bosinger SE, Promislow DE, Miller JS, Waller EK, Blazar BR, Kean LS.

Sci Transl Med. 2015 Nov 25;7(315):315ra191. doi: 10.1126/scitranslmed.aad3231.

28.

Metabolic Characterization of the Common Marmoset (Callithrix jacchus).

Go YM, Liang Y, Uppal K, Soltow QA, Promislow DE, Wachtman LM, Jones DP.

PLoS One. 2015 Nov 18;10(11):e0142916. doi: 10.1371/journal.pone.0142916. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0147880.

29.

The impacts of Wolbachia and the microbiome on mate choice in Drosophila melanogaster.

Arbuthnott D, Levin TC, Promislow DE.

J Evol Biol. 2016 Feb;29(2):461-8. doi: 10.1111/jeb.12788. Epub 2015 Nov 28.

30.

The effects of graded levels of calorie restriction: IV. Non-linear change in behavioural phenotype of mice in response to short-term calorie restriction.

Lusseau D, Mitchell SE, Barros C, Derous D, Green C, Chen L, Han JD, Wang Y, Promislow DE, Douglas A, Speakman JR.

Sci Rep. 2015 Aug 25;5:13198. doi: 10.1038/srep13198.

31.

The effects of graded levels of calorie restriction: III. Impact of short term calorie and protein restriction on mean daily body temperature and torpor use in the C57BL/6 mouse.

Mitchell SE, Delville C, Konstantopedos P, Derous D, Green CL, Chen L, Han JD, Wang Y, Promislow DE, Douglas A, Lusseau D, Speakman JR.

Oncotarget. 2015 Jul 30;6(21):18314-37.

32.

MetabNet: An R Package for Metabolic Association Analysis of High-Resolution Metabolomics Data.

Uppal K, Soltow QA, Promislow DE, Wachtman LM, Quyyumi AA, Jones DP.

Front Bioeng Biotechnol. 2015 Jun 11;3:87. doi: 10.3389/fbioe.2015.00087. eCollection 2015.

33.

The effects of age and dietary restriction on the tissue-specific metabolome of Drosophila.

Laye MJ, Tran V, Jones DP, Kapahi P, Promislow DE.

Aging Cell. 2015 Oct;14(5):797-808. doi: 10.1111/acel.12358. Epub 2015 Jun 18.

34.

The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse.

Mitchell SE, Tang Z, Kerbois C, Delville C, Konstantopedos P, Bruel A, Derous D, Green C, Aspden RM, Goodyear SR, Chen L, Han JJ, Wang Y, Promislow DE, Lusseau D, Douglas A, Speakman JR.

Oncotarget. 2015 Jun 30;6(18):15902-30.

35.

The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice.

Mitchell SE, Delville C, Konstantopedos P, Hurst J, Derous D, Green C, Chen L, Han JJ, Wang Y, Promislow DE, Lusseau D, Douglas A, Speakman JR.

Oncotarget. 2015 Sep 15;6(27):23213-37.

36.

Immune parameter analysis of children with sickle cell disease on hydroxycarbamide or chronic transfusion therapy.

Nickel RS, Osunkwo I, Garrett A, Robertson J, Archer DR, Promislow DE, Horan JT, Hendrickson JE, Kean LS.

Br J Haematol. 2015 May;169(4):574-83. doi: 10.1111/bjh.13326. Epub 2015 Mar 5.

37.

Fertile waters for aging research.

Wang AM, Promislow DEL, Kaeberlein M.

Cell. 2015 Feb 26;160(5):814-815. doi: 10.1016/j.cell.2015.02.026.

38.

Invariance and plasticity in the Drosophila melanogaster metabolomic network in response to temperature.

Hariharan R, Hoffman JM, Thomas AS, Soltow QA, Jones DP, Promislow DE.

BMC Syst Biol. 2014 Dec 24;8:139. doi: 10.1186/s12918-014-0139-6.

39.

Metabolome-wide association study of phenylalanine in plasma of common marmosets.

Go YM, Walker DI, Soltow QA, Uppal K, Wachtman LM, Strobel FH, Pennell K, Promislow DE, Jones DP.

Amino Acids. 2015 Mar;47(3):589-601. doi: 10.1007/s00726-014-1893-x. Epub 2014 Dec 21.

40.

Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogaster.

Hoffman JM, Soltow QA, Li S, Sidik A, Jones DP, Promislow DE.

Aging Cell. 2014 Aug;13(4):596-604. doi: 10.1111/acel.12215. Epub 2014 Mar 18.

41.

Development. Chemical warfare in the battle of the sexes.

Promislow DE, Kaeberlein M.

Science. 2014 Jan 31;343(6170):491-2. doi: 10.1126/science.1250174. No abstract available.

PMID:
24482469
42.

Robert L. Perlman, evolution & medicine.

Promislow DE.

Evol Med Public Health. 2014 Jan;2014(1):10-1. doi: 10.1093/emph/eou001. Epub 2014 Jan 7. No abstract available.

43.

Characterization of plasma thiol redox potential in a common marmoset model of aging.

Roede JR, Uppal K, Liang Y, Promislow DE, Wachtman LM, Jones DP.

Redox Biol. 2013 Jul 18;1:387-93. doi: 10.1016/j.redox.2013.06.003. eCollection 2013.

44.

Reproductive capability is associated with lifespan and cause of death in companion dogs.

Hoffman JM, Creevy KE, Promislow DE.

PLoS One. 2013 Apr 17;8(4):e61082. doi: 10.1371/journal.pone.0061082. Print 2013.

45.

The size-life span trade-off decomposed: why large dogs die young.

Kraus C, Pavard S, Promislow DE.

Am Nat. 2013 Apr;181(4):492-505. doi: 10.1086/669665. Epub 2013 Feb 21. Erratum in: Am Nat. 2013 Apr;181(4):583.

PMID:
23535614
46.

A comparative assessment of univariate longevity measures using zoological animal records.

Moorad JA, Promislow DE, Flesness N, Miller RA.

Aging Cell. 2012 Dec;11(6):940-8. doi: 10.1111/j.1474-9726.2012.00861.x. Epub 2012 Aug 12.

47.

Significant mobilization of both conventional and regulatory T cells with AMD3100.

Kean LS, Sen S, Onabajo O, Singh K, Robertson J, Stempora L, Bonifacino AC, Metzger ME, Promislow DE, Mattapallil JJ, Donahue RE.

Blood. 2011 Dec 15;118(25):6580-90. doi: 10.1182/blood-2011-06-359331. Epub 2011 Oct 11.

48.

Mortality in north american dogs from 1984 to 2004: an investigation into age-, size-, and breed-related causes of death.

Fleming JM, Creevy KE, Promislow DE.

J Vet Intern Med. 2011 Mar-Apr;25(2):187-98. doi: 10.1111/j.1939-1676.2011.0695.x. Epub 2011 Feb 25.

49.

A network perspective on metabolism and aging.

Soltow QA, Jones DP, Promislow DE.

Integr Comp Biol. 2010 Nov;50(5):844-54. doi: 10.1093/icb/icq094. Epub 2010 Jul 12. Review.

50.

Evolutionary demography and quantitative genetics: age-specific survival as a threshold trait.

Moorad JA, Promislow DE.

Proc Biol Sci. 2011 Jan 7;278(1702):144-51. doi: 10.1098/rspb.2010.0992. Epub 2010 Jul 21.

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