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Items: 32


Next-generation sequencing reveals a controlled immune response to Zaire Ebola virus challenge in cynomolgus macaques immunized with vesicular stomatitis virus expressing Zaire Ebola virus glycoprotein (VSVΔG/EBOVgp).

Barrenas F, Green RR, Thomas MJ, Law GL, Proll SC, Engelmann F, Messaoudi I, Marzi A, Feldmann H, Katze MG.

Clin Vaccine Immunol. 2015 Mar;22(3):354-6. doi: 10.1128/CVI.00733-14. Epub 2015 Jan 14.


Influenza virus A/Anhui/1/2013 (H7N9) replicates efficiently in the upper and lower respiratory tracts of cynomolgus macaques.

de Wit E, Rasmussen AL, Feldmann F, Bushmaker T, Martellaro C, Haddock E, Okumura A, Proll SC, Chang J, Gardner D, Katze MG, Munster VJ, Feldmann H.

MBio. 2014 Aug 12;5(4). pii: e01331-14. doi: 10.1128/mBio.01331-14.


A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes.

Suthar MS, Brassil MM, Blahnik G, McMillan A, Ramos HJ, Proll SC, Belisle SE, Katze MG, Gale M Jr.

PLoS Pathog. 2013 Feb;9(2):e1003168. doi: 10.1371/journal.ppat.1003168. Epub 2013 Feb 7.


Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses.

Cho H, Proll SC, Szretter KJ, Katze MG, Gale M Jr, Diamond MS.

Nat Med. 2013 Apr;19(4):458-64. doi: 10.1038/nm.3108. Epub 2013 Mar 3.


Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis.

Rasmussen AL, Wang IM, Shuhart MC, Proll SC, He Y, Cristescu R, Roberts C, Carter VS, Williams CM, Diamond DL, Bryan JT, Ulrich R, Korth MJ, Thomassen LV, Katze MG.

Virology. 2012 Aug 15;430(1):43-52. doi: 10.1016/j.virol.2012.04.011. Epub 2012 May 16.


Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation.

Navare AT, Sova P, Purdy DE, Weiss JM, Wolf-Yadlin A, Korth MJ, Chang ST, Proll SC, Jahan TA, Krasnoselsky AL, Palermo RE, Katze MG.

Virology. 2012 Jul 20;429(1):37-46. doi: 10.1016/j.virol.2012.03.026. Epub 2012 Apr 26.


Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses.

Bedard KM, Wang ML, Proll SC, Loo YM, Katze MG, Gale M Jr, Iadonato SP.

J Virol. 2012 Jul;86(13):7334-44. doi: 10.1128/JVI.06867-11. Epub 2012 Apr 24.


Proteome and computational analyses reveal new insights into the mechanisms of hepatitis C virus-mediated liver disease posttransplantation.

Diamond DL, Krasnoselsky AL, Burnum KE, Monroe ME, Webb-Robertson BJ, McDermott JE, Yeh MM, Dzib JF, Susnow N, Strom S, Proll SC, Belisle SE, Purdy DE, Rasmussen AL, Walters KA, Jacobs JM, Gritsenko MA, Camp DG, Bhattacharya R, Perkins JD, Carithers RL Jr, Liou IW, Larson AM, Benecke A, Waters KM, Smith RD, Katze MG.

Hepatology. 2012 Jul;56(1):28-38. doi: 10.1002/hep.25649. Epub 2012 Apr 24.


Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients.

Rasmussen AL, Tchitchek N, Susnow NJ, Krasnoselsky AL, Diamond DL, Yeh MM, Proll SC, Korth MJ, Walters KA, Lederer S, Larson AM, Carithers RL, Benecke A, Katze MG.

Hepatology. 2012 Jul;56(1):17-27. doi: 10.1002/hep.25612. Epub 2012 Jun 5.


The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.

Tisoncik JR, Billharz R, Burmakina S, Belisle SE, Proll SC, Korth MJ, García-Sastre A, Katze MG.

J Gen Virol. 2011 Sep;92(Pt 9):2093-104. doi: 10.1099/vir.0.032060-0. Epub 2011 May 18. Erratum in: J Gen Virol. 2011 Oct;92(Pt 10):2466. Garcíia-Sastre, Adolfo [corrected to García-Sastre, Adolfo].


A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.

Aderem A, Adkins JN, Ansong C, Galagan J, Kaiser S, Korth MJ, Law GL, McDermott JG, Proll SC, Rosenberger C, Schoolnik G, Katze MG.

MBio. 2011 Mar 1;2(1):e00325-10. doi: 10.1128/mBio.00325-10.


Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques.

Safronetz D, Rockx B, Feldmann F, Belisle SE, Palermo RE, Brining D, Gardner D, Proll SC, Marzi A, Tsuda Y, Lacasse RA, Kercher L, York A, Korth MJ, Long D, Rosenke R, Shupert WL, Aranda CA, Mattoon JS, Kobasa D, Kobinger G, Li Y, Taubenberger JK, Richt JA, Parnell M, Ebihara H, Kawaoka Y, Katze MG, Feldmann H.

J Virol. 2011 Feb;85(3):1214-23. doi: 10.1128/JVI.01848-10. Epub 2010 Nov 17.


Viral replication rate regulates clinical outcome and CD8 T cell responses during highly pathogenic H5N1 influenza virus infection in mice.

Hatta Y, Hershberger K, Shinya K, Proll SC, Dubielzig RR, Hatta M, Katze MG, Kawaoka Y, Suresh M.

PLoS Pathog. 2010 Oct 7;6(10):e1001139. doi: 10.1371/journal.ppat.1001139.


Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-alpha signaling and increased severity of 1918 pandemic influenza virus infection.

Belisle SE, Tisoncik JR, Korth MJ, Carter VS, Proll SC, Swayne DE, Pantin-Jackwood M, Tumpey TM, Katze MG.

J Virol. 2010 Dec;84(24):12576-88. doi: 10.1128/JVI.01310-10. Epub 2010 Oct 6.


Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection.

Cilloniz C, Pantin-Jackwood MJ, Ni C, Goodman AG, Peng X, Proll SC, Carter VS, Rosenzweig ER, Szretter KJ, Katz JM, Korth MJ, Swayne DE, Tumpey TM, Katze MG.

J Virol. 2010 Aug;84(15):7613-24. doi: 10.1128/JVI.00553-10. Epub 2010 May 26.


Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics.

Diamond DL, Syder AJ, Jacobs JM, Sorensen CM, Walters KA, Proll SC, McDermott JE, Gritsenko MA, Zhang Q, Zhao R, Metz TO, Camp DG 2nd, Waters KM, Smith RD, Rice CM, Katze MG.

PLoS Pathog. 2010 Jan;6(1):e1000719. doi: 10.1371/journal.ppat.1000719. Epub 2010 Jan 8.


The alpha/beta interferon receptor provides protection against influenza virus replication but is dispensable for inflammatory response signaling.

Goodman AG, Zeng H, Proll SC, Peng X, Cillóniz C, Carter VS, Korth MJ, Tumpey TM, Katze MG.

J Virol. 2010 Feb;84(4):2027-37. doi: 10.1128/JVI.01595-09. Epub 2009 Nov 25.


Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes.

Cillóniz C, Shinya K, Peng X, Korth MJ, Proll SC, Aicher LD, Carter VS, Chang JH, Kobasa D, Feldmann F, Strong JE, Feldmann H, Kawaoka Y, Katze MG.

PLoS Pathog. 2009 Oct;5(10):e1000604. doi: 10.1371/journal.ppat.1000604. Epub 2009 Oct 2.


The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways.

Billharz R, Zeng H, Proll SC, Korth MJ, Lederer S, Albrecht R, Goodman AG, Rosenzweig E, Tumpey TM, García-Sastre A, Katze MG.

J Virol. 2009 Oct;83(20):10557-70. doi: 10.1128/JVI.00330-09. Epub 2009 Aug 12.


P58(IPK): a novel "CIHD" member of the host innate defense response against pathogenic virus infection.

Goodman AG, Fornek JL, Medigeshi GR, Perrone LA, Peng X, Dyer MD, Proll SC, Knoblaugh SE, Carter VS, Korth MJ, Nelson JA, Tumpey TM, Katze MG.

PLoS Pathog. 2009 May;5(5):e1000438. doi: 10.1371/journal.ppat.1000438. Epub 2009 May 22.


Impaired cholesterol biosynthesis in a neuronal cell line persistently infected with measles virus.

Robinzon S, Dafa-Berger A, Dyer MD, Paeper B, Proll SC, Teal TH, Rom S, Fishman D, Rager-Zisman B, Katze MG.

J Virol. 2009 Jun;83(11):5495-504. doi: 10.1128/JVI.01880-08. Epub 2009 Mar 18.


Host responses to wild-type and attenuated herpes simplex virus infection in the absence of Stat1.

Pasieka TJ, Cilloniz C, Lu B, Teal TH, Proll SC, Katze MG, Leib DA.

J Virol. 2009 Mar;83(5):2075-87. doi: 10.1128/JVI.02007-08. Epub 2008 Dec 24.


Down-regulation of hepcidin in porphyria cutanea tarda.

Ajioka RS, Phillips JD, Weiss RB, Dunn DM, Smit MW, Proll SC, Katze MG, Kushner JP.

Blood. 2008 Dec 1;112(12):4723-8. doi: 10.1182/blood-2008-02-138222. Epub 2008 Sep 22.


Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction.

Diamond DL, Jacobs JM, Paeper B, Proll SC, Gritsenko MA, Carithers RL Jr, Larson AM, Yeh MM, Camp DG 2nd, Smith RD, Katze MG.

Hepatology. 2007 Sep;46(3):649-57.


High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations.

Wallace JC, Korth MJ, Paeper B, Proll SC, Thomas MJ, Magness CL, Iadonato SP, Nelson C, Katze MG.

BMC Genomics. 2007 Jan 23;8:28.


The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism.

Goodman AG, Smith JA, Balachandran S, Perwitasari O, Proll SC, Thomas MJ, Korth MJ, Barber GN, Schiff LA, Katze MG.

J Virol. 2007 Mar;81(5):2221-30. Epub 2006 Dec 13.


Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus.

Kash JC, Tumpey TM, Proll SC, Carter V, Perwitasari O, Thomas MJ, Basler CF, Palese P, Taubenberger JK, García-Sastre A, Swayne DE, Katze MG.

Nature. 2006 Oct 5;443(7111):578-81. Epub 2006 Sep 27.


HepatoProteomics: applying proteomic technologies to the study of liver function and disease.

Diamond DL, Proll SC, Jacobs JM, Chan EY, Camp DG 2nd, Smith RD, Katze MG.

Hepatology. 2006 Aug;44(2):299-308. Review.


Functional genomic analysis of herpes simplex virus type 1 counteraction of the host innate response.

Pasieka TJ, Baas T, Carter VS, Proll SC, Katze MG, Leib DA.

J Virol. 2006 Aug;80(15):7600-12.


Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence.

Kash JC, Mühlberger E, Carter V, Grosch M, Perwitasari O, Proll SC, Thomas MJ, Weber F, Klenk HD, Katze MG.

J Virol. 2006 Mar;80(6):3009-20.


Functional gene analysis of individual response to challenge of SIVmac239 in M. mulatta PBMC culture.

Thomas MJ, Agy MB, Proll SC, Paeper BW, Li Y, Jensen KL, Korth MJ, Katze MG.

Virology. 2006 Apr 25;348(1):242-52. Epub 2006 Jan 23.


Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.

Magness CL, Fellin PC, Thomas MJ, Korth MJ, Agy MB, Proll SC, Fitzgibbon M, Scherer CA, Miner DG, Katze MG, Iadonato SP.

Genome Biol. 2005;6(7):R60. Epub 2005 Jun 30.

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