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Items: 1 to 50 of 101

1.

Dysregulated integrin αVβ3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis.

Wang Q, Onuma K, Liu C, Wong H, Bloom MS, Elliott EE, Cao RR, Hu N, Lingampalli N, Sharpe O, Zhao X, Sohn DH, Lepus CM, Sokolove J, Mao R, Cisar CT, Raghu H, Chu CR, Giori NJ, Willingham SB, Prohaska SS, Cheng Z, Weissman IL, Robinson WH.

JCI Insight. 2019 Sep 19;4(18). pii: 128616. doi: 10.1172/jci.insight.128616.

2.

Serial Synapse Formation through Filopodial Competition for Synaptic Seeding Factors.

Özel MN, Kulkarni A, Hasan A, Brummer J, Moldenhauer M, Daumann IM, Wolfenberg H, Dercksen VJ, Kiral FR, Weiser M, Prohaska S, von Kleist M, Hiesinger PR.

Dev Cell. 2019 Aug 19;50(4):447-461.e8. doi: 10.1016/j.devcel.2019.06.014. Epub 2019 Jul 25.

PMID:
31353313
3.

Three-dimensional quantitative photoacoustic tomography using an adjoint radiance Monte Carlo model and gradient descent.

Buchmann J, Kaplan B, Powell S, Prohaska S, Laufer J.

J Biomed Opt. 2019 Jun;24(6):1-13. doi: 10.1117/1.JBO.24.6.066001.

4.

Impact of E-Cadherin and β-Catenin as Prognostic Factor in Renal Cell Carcinoma with Tumor Thrombus of the Vena Cava.

Spachmann PJ, Breyer J, Kalogirou C, Lausenmeyer EM, Weber F, Prohaska S, Denzinger S, Burger M, Kübler H, Otto W, Vergho D.

Urol Int. 2019;102(4):413-420. doi: 10.1159/000497279. Epub 2019 Mar 7.

PMID:
30844790
5.

First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers.

Sikic BI, Lakhani N, Patnaik A, Shah SA, Chandana SR, Rasco D, Colevas AD, O'Rourke T, Narayanan S, Papadopoulos K, Fisher GA, Villalobos V, Prohaska SS, Howard M, Beeram M, Chao MP, Agoram B, Chen JY, Huang J, Axt M, Liu J, Volkmer JP, Majeti R, Weissman IL, Takimoto CH, Supan D, Wakelee HA, Aoki R, Pegram MD, Padda SK.

J Clin Oncol. 2019 Apr 20;37(12):946-953. doi: 10.1200/JCO.18.02018. Epub 2019 Feb 27.

PMID:
30811285
6.

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice.

Kwon HS, Logan AC, Chhabra A, Pang WW, Czechowicz A, Tate K, Le A, Poyser J, Hollis R, Kelly BV, Kohn DB, Weissman IL, Prohaska SS, Shizuru JA.

Blood. 2019 May 9;133(19):2104-2108. doi: 10.1182/blood-2018-06-853879. Epub 2019 Jan 7. No abstract available.

PMID:
30617195
7.

A Switch in Microtubule Orientation during C. elegans Meiosis.

Redemann S, Lantzsch I, Lindow N, Prohaska S, Srayko M, Müller-Reichert T.

Curr Biol. 2018 Sep 24;28(18):2991-2997.e2. doi: 10.1016/j.cub.2018.07.012. Epub 2018 Sep 6.

8.

Quantification of three-dimensional spindle architecture.

Lindow N, Redemann S, Brünig F, Fabig G, Müller-Reichert T, Prohaska S.

Methods Cell Biol. 2018;145:45-64. doi: 10.1016/bs.mcb.2018.03.012.

PMID:
29957215
9.

Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals.

Jin EJ, Kiral FR, Ozel MN, Burchardt LS, Osterland M, Epstein D, Wolfenberg H, Prohaska S, Hiesinger PR.

Curr Biol. 2018 Apr 2;28(7):1027-1038.e4. doi: 10.1016/j.cub.2018.02.032. Epub 2018 Mar 15.

10.

Intravenous immunoglobulin fails to improve ARDS in patients undergoing ECMO therapy.

Prohaska S, Schirner A, Bashota A, Körner A, Blumenstock G, Haeberle HA.

J Intensive Care. 2018 Feb 26;6:11. doi: 10.1186/s40560-018-0278-8. eCollection 2018.

11.

Toward a mechanistic explanation of phenotypic evolution: The need for a theory of theory integration.

Laubichler MD, Prohaska SJ, Stadler PF.

J Exp Zool B Mol Dev Evol. 2018 Jan;330(1):5-14. doi: 10.1002/jez.b.22785. Epub 2018 Jan 22.

PMID:
29356321
12.

Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem.

Prohaska SJ, Berkemer SJ, Gärtner F, Gatter T, Retzlaff N; Students of the Graphs and Biological Networks Lab 2017, Höner Zu Siederdissen C, Stadler PF.

J Math Biol. 2018 Aug;77(2):313-341. doi: 10.1007/s00285-017-1197-3. Epub 2017 Dec 19.

13.

Automated segmentation of complex patterns in biological tissues: Lessons from stingray tessellated cartilage.

Knötel D, Seidel R, Prohaska S, Dean MN, Baum D.

PLoS One. 2017 Dec 13;12(12):e0188018. doi: 10.1371/journal.pone.0188018. eCollection 2017.

14.

Ecological plant epigenetics: Evidence from model and non-model species, and the way forward.

Richards CL, Alonso C, Becker C, Bossdorf O, Bucher E, Colomé-Tatché M, Durka W, Engelhardt J, Gaspar B, Gogol-Döring A, Grosse I, van Gurp TP, Heer K, Kronholm I, Lampei C, Latzel V, Mirouze M, Opgenoorth L, Paun O, Prohaska SJ, Rensing SA, Stadler PF, Trucchi E, Ullrich K, Verhoeven KJF.

Ecol Lett. 2017 Dec;20(12):1576-1590. doi: 10.1111/ele.12858. Epub 2017 Oct 12. Review.

PMID:
29027325
15.

Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes.

Indrischek H, Prohaska SJ, Gurevich VV, Gurevich EV, Stadler PF.

BMC Evol Biol. 2017 Jul 6;17(1):163. doi: 10.1186/s12862-017-1001-4.

16.

C. elegans chromosomes connect to centrosomes by anchoring into the spindle network.

Redemann S, Baumgart J, Lindow N, Shelley M, Nazockdast E, Kratz A, Prohaska S, Brugués J, Fürthauer S, Müller-Reichert T.

Nat Commun. 2017 May 11;8:15288. doi: 10.1038/ncomms15288.

17.

The Role of Titanium Surface Nanostructuring on Preosteoblast Morphology, Adhesion, and Migration.

Zhukova Y, Hiepen C, Knaus P, Osterland M, Prohaska S, Dunlop JWC, Fratzl P, Skorb EV.

Adv Healthc Mater. 2017 Aug;6(15). doi: 10.1002/adhm.201601244. Epub 2017 Mar 30.

PMID:
28371540
18.

Design specifications for cellular regulation.

Krakauer DC, Müller L, Prohaska SJ, Stadler PF.

Theory Biosci. 2016 Dec;135(4):231-240. Epub 2016 Nov 18.

PMID:
27864730
19.

Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20.

Weiskopf K, Anderson KL, Ito D, Schnorr PJ, Tomiyasu H, Ring AM, Bloink K, Efe J, Rue S, Lowery D, Barkal A, Prohaska S, McKenna KM, Cornax I, O'Brien TD, O'Sullivan MG, Weissman IL, Modiano JF.

Cancer Immunol Res. 2016 Dec;4(12):1072-1087. Epub 2016 Nov 14.

20.

NBLAST: Rapid, Sensitive Comparison of Neuronal Structure and Construction of Neuron Family Databases.

Costa M, Manton JD, Ostrovsky AD, Prohaska S, Jefferis GS.

Neuron. 2016 Jul 20;91(2):293-311. doi: 10.1016/j.neuron.2016.06.012. Epub 2016 Jun 30.

21.

The paralog-to-contig assignment problem: high quality gene models from fragmented assemblies.

Indrischek H, Wieseke N, Stadler PF, Prohaska SJ.

Algorithms Mol Biol. 2016 Feb 24;11:1. doi: 10.1186/s13015-016-0063-y. eCollection 2016.

22.

Algebraic Dynamic Programming over general data structures.

zu Siederdissen CH, Prohaska SJ, Stadler PF.

BMC Bioinformatics. 2015;16 Suppl 19:S2. doi: 10.1186/1471-2105-16-S19-S2. Epub 2015 Dec 16.

23.

The relativity of biological function.

Laubichler MD, Stadler PF, Prohaska SJ, Nowick K.

Theory Biosci. 2015 Dec;134(3-4):143-7. doi: 10.1007/s12064-015-0215-5. Epub 2015 Oct 8.

PMID:
26449352
24.

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential.

Liu J, Wang L, Zhao F, Tseng S, Narayanan C, Shura L, Willingham S, Howard M, Prohaska S, Volkmer J, Chao M, Weissman IL, Majeti R.

PLoS One. 2015 Sep 21;10(9):e0137345. doi: 10.1371/journal.pone.0137345. eCollection 2015.

25.

Kiwi genome provides insights into evolution of a nocturnal lifestyle.

Le Duc D, Renaud G, Krishnan A, Almén MS, Huynen L, Prohaska SJ, Ongyerth M, Bitarello BD, Schiöth HB, Hofreiter M, Stadler PF, Prüfer K, Lambert D, Kelso J, Schöneberg T.

Genome Biol. 2015 Jul 23;16:147. doi: 10.1186/s13059-015-0711-4.

26.

The ancestor of modern Holozoa acquired the CCA-adding enzyme from Alphaproteobacteria by horizontal gene transfer.

Betat H, Mede T, Tretbar S, Steiner L, Stadler PF, Mörl M, Prohaska SJ.

Nucleic Acids Res. 2015 Aug 18;43(14):6739-46. doi: 10.1093/nar/gkv631. Epub 2015 Jun 27.

27.

Valvulopathy consistent with endocarditis in an Argentine boa (Boa constrictor occidentalis).

Wernick MB, Novo-Matos J, Ebling A, Kühn K, Ruetten M, Hilbe M, Howard J, Chang R, Prohaska S, Hatt JM.

J Zoo Wildl Med. 2015 Mar;46(1):124-9.

PMID:
25831585
28.

Registering 2D and 3D imaging data of bone during healing.

Hoerth RM, Baum D, Knötel D, Prohaska S, Willie BM, Duda GN, Hege HC, Fratzl P, Wagermaier W.

Connect Tissue Res. 2015 Apr;56(2):133-43. doi: 10.3109/03008207.2015.1005210.

PMID:
25825970
29.

Automated stitching of microtubule centerlines across serial electron tomograms.

Weber B, Tranfield EM, Höög JL, Baum D, Antony C, Hyman T, Verbavatz JM, Prohaska S.

PLoS One. 2014 Dec 1;9(12):e113222. doi: 10.1371/journal.pone.0113222. eCollection 2014.

30.

Orthology detection combining clustering and synteny for very large datasets.

Lechner M, Hernandez-Rosales M, Doerr D, Wieseke N, Thévenin A, Stoye J, Hartmann RK, Prohaska SJ, Stadler PF.

PLoS One. 2014 Aug 19;9(8):e105015. doi: 10.1371/journal.pone.0105015. eCollection 2014.

31.

The CHR site: definition and genome-wide identification of a cell cycle transcriptional element.

Müller GA, Wintsche A, Stangner K, Prohaska SJ, Stadler PF, Engeland K.

Nucleic Acids Res. 2014;42(16):10331-50. doi: 10.1093/nar/gku696. Epub 2014 Aug 8.

32.

The segmentation of microtubules in electron tomograms using Amira.

Redemann S, Weber B, Möller M, Verbavatz JM, Hyman AA, Baum D, Prohaska S, Müller-Reichert T.

Methods Mol Biol. 2014;1136:261-78. doi: 10.1007/978-1-4939-0329-0_12.

PMID:
24633801
33.

[Intramedullary nailing vs. locking plate osteosynthesis in proximal humeral fractures: Long-term outcome].

von Rüden C, Trapp O, Hierholzer C, Prohaska S, Wurm S, Bühren V.

Unfallchirurg. 2015 Aug;118(8):686-92. doi: 10.1007/s00113-013-2530-y. German.

PMID:
24402670
34.

[Epidemiologic study of an outbreak of progressive rhinitis atrophicans in a breeding sow facility in Lucerne canton].

Nathues C, Estermann A, Fuschini E, Giese C, Zimmermann W, Huber H, Prohaska S, Schüpbach-Regula G.

Schweiz Arch Tierheilkd. 2013 Dec;155(12):681-3. doi: 10.1024/0036-7281/a000534. German. No abstract available.

35.

MALDI-TOF MS for identification of porcine Brachyspira species.

Prohaska S, Pflüger V, Ziegler D, Scherrer S, Frei D, Lehmann A, Wittenbrink MM, Huber H.

Lett Appl Microbiol. 2014 Mar;58(3):292-8. doi: 10.1111/lam.12189. Epub 2013 Nov 18.

36.

Quantitative analysis of fecal flora in goat kids with and without floppy kid syndrome.

Bleul U, Fassbind N, Ghielmetti G, Zoller D, Liesegang A, Hässig M, Wittenbrink MM, Prohaska S.

J Vet Intern Med. 2013 Sep-Oct;27(5):1283-6. doi: 10.1111/jvim.12160. Epub 2013 Aug 19.

37.

Chromatin computation: epigenetic inheritance as a pattern reconstruction problem.

Arnold C, Stadler PF, Prohaska SJ.

J Theor Biol. 2013 Nov 7;336:61-74. doi: 10.1016/j.jtbi.2013.07.012. Epub 2013 Jul 20.

PMID:
23880640
38.

The African coelacanth genome provides insights into tetrapod evolution.

Amemiya CT, Alföldi J, Lee AP, Fan S, Philippe H, Maccallum I, Braasch I, Manousaki T, Schneider I, Rohner N, Organ C, Chalopin D, Smith JJ, Robinson M, Dorrington RA, Gerdol M, Aken B, Biscotti MA, Barucca M, Baurain D, Berlin AM, Blatch GL, Buonocore F, Burmester T, Campbell MS, Canapa A, Cannon JP, Christoffels A, De Moro G, Edkins AL, Fan L, Fausto AM, Feiner N, Forconi M, Gamieldien J, Gnerre S, Gnirke A, Goldstone JV, Haerty W, Hahn ME, Hesse U, Hoffmann S, Johnson J, Karchner SI, Kuraku S, Lara M, Levin JZ, Litman GW, Mauceli E, Miyake T, Mueller MG, Nelson DR, Nitsche A, Olmo E, Ota T, Pallavicini A, Panji S, Picone B, Ponting CP, Prohaska SJ, Przybylski D, Saha NR, Ravi V, Ribeiro FJ, Sauka-Spengler T, Scapigliati G, Searle SM, Sharpe T, Simakov O, Stadler PF, Stegeman JJ, Sumiyama K, Tabbaa D, Tafer H, Turner-Maier J, van Heusden P, White S, Williams L, Yandell M, Brinkmann H, Volff JN, Tabin CJ, Shubin N, Schartl M, Jaffe DB, Postlethwait JH, Venkatesh B, Di Palma F, Lander ES, Meyer A, Lindblad-Toh K.

Nature. 2013 Apr 18;496(7445):311-6. doi: 10.1038/nature12027.

39.

Transcriptional regulation by histone modifications: towards a theory of chromatin re-organization during stem cell differentiation.

Binder H, Steiner L, Przybilla J, Rohlf T, Prohaska S, Galle J.

Phys Biol. 2013 Apr;10(2):026006. doi: 10.1088/1478-3975/10/2/026006. Epub 2013 Mar 12.

PMID:
23481318
40.

Surveillance of bovine tuberculosis and risk estimation of a future reservoir formation in wildlife in Switzerland and Liechtenstein.

Schöning JM, Cerny N, Prohaska S, Wittenbrink MM, Smith NH, Bloemberg G, Pewsner M, Schiller I, Origgi FC, Ryser-Degiorgis MP.

PLoS One. 2013;8(1):e54253. doi: 10.1371/journal.pone.0054253. Epub 2013 Jan 21.

41.

A global genome segmentation method for exploration of epigenetic patterns.

Steiner L, Hopp L, Wirth H, Galle J, Binder H, Prohaska SJ, Rohlf T.

PLoS One. 2012;7(10):e46811. doi: 10.1371/journal.pone.0046811. Epub 2012 Oct 12.

42.

[Infection related fertility disorders in Swiss pig breeding farms at the end of the postweaning multisystemic wasting syndrome (PMWS) epizooty].

Handke M, Engels M, Prohaska S, Keller Ch, Brugnera E, Sydler T, Sidler X.

Schweiz Arch Tierheilkd. 2012 Oct;154(10):437-44. doi: 10.1024/0036-7281/a000380. German.

43.

Modeling the dynamic epigenome: from histone modifications towards self-organizing chromatin.

Rohlf T, Steiner L, Przybilla J, Prohaska S, Binder H, Galle J.

Epigenomics. 2012 Apr;4(2):205-19. doi: 10.2217/epi.11.117.

PMID:
22449191
44.

"Hypothesis for the modern RNA world": a pervasive non-coding RNA-based genetic regulation is a prerequisite for the emergence of multicellular complexity.

Lozada-Chávez I, Stadler PF, Prohaska SJ.

Orig Life Evol Biosph. 2011 Dec;41(6):587-607. doi: 10.1007/s11084-011-9262-1. Epub 2012 Feb 10.

PMID:
22322874
45.

Automated tracing of microtubules in electron tomograms of plastic embedded samples of Caenorhabditis elegans embryos.

Weber B, Greenan G, Prohaska S, Baum D, Hege HC, Müller-Reichert T, Hyman AA, Verbavatz JM.

J Struct Biol. 2012 May;178(2):129-38. doi: 10.1016/j.jsb.2011.12.004. Epub 2011 Dec 13.

PMID:
22182731
46.

Large-scale automated histology in the pursuit of connectomes.

Kleinfeld D, Bharioke A, Blinder P, Bock DD, Briggman KL, Chklovskii DB, Denk W, Helmstaedter M, Kaufhold JP, Lee WC, Meyer HS, Micheva KD, Oberlaender M, Prohaska S, Reid RC, Smith SJ, Takemura S, Tsai PS, Sakmann B.

J Neurosci. 2011 Nov 9;31(45):16125-38. doi: 10.1523/JNEUROSCI.4077-11.2011. Review.

47.

Automated segmentation of electron tomograms for a quantitative description of actin filament networks.

Rigort A, Günther D, Hegerl R, Baum D, Weber B, Prohaska S, Medalia O, Baumeister W, Hege HC.

J Struct Biol. 2012 Jan;177(1):135-44. doi: 10.1016/j.jsb.2011.08.012. Epub 2011 Sep 1.

PMID:
21907807
48.

Protein-coding structured RNAs: A computational survey of conserved RNA secondary structures overlapping coding regions in drosophilids.

Findeiss S, Engelhardt J, Prohaska SJ, Stadler PF.

Biochimie. 2011 Nov;93(11):2019-23. doi: 10.1016/j.biochi.2011.07.023. Epub 2011 Jul 31.

PMID:
21835221
49.

Hox clusters of the bichir (Actinopterygii, Polypterus senegalus) highlight unique patterns of sequence evolution in gnathostome phylogeny.

Raincrow JD, Dewar K, Stocsits C, Prohaska SJ, Amemiya CT, Stadler PF, Chiu CH.

J Exp Zool B Mol Dev Evol. 2011 Sep 15;316(6):451-64. doi: 10.1002/jez.b.21420. Epub 2011 Jun 17.

PMID:
21688387
50.

Proteinortho: detection of (co-)orthologs in large-scale analysis.

Lechner M, Findeiss S, Steiner L, Marz M, Stadler PF, Prohaska SJ.

BMC Bioinformatics. 2011 Apr 28;12:124. doi: 10.1186/1471-2105-12-124.

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