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Items: 34

1.

Transcutaneous immunization with CD40 ligation boosts cytotoxic T lymphocyte mediated antitumor immunity independent of CD4 helper cells in mice.

Bialojan A, Sohl J, Rausch J, Aranda Lopez P, Denny M, Langguth P, Hartmann AK, Yagita H, Probst HC, Schild H, Radsak MP.

Eur J Immunol. 2019 Nov;49(11):2083-2094. doi: 10.1002/eji.201848039. Epub 2019 Aug 19.

PMID:
31393597
2.

Intervention of Inflammatory Monocyte Activity Limits Dermal Fibrosis.

Haub J, Roehrig N, Uhrin P, Schabbauer G, Eulberg D, Melchior F, Shahneh F, Probst HC, Becker C, Steinbrink K, Raker VK.

J Invest Dermatol. 2019 Oct;139(10):2144-2153. doi: 10.1016/j.jid.2019.04.006. Epub 2019 Apr 27.

PMID:
31039360
3.

Transcriptome 3'end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma.

Ogorodnikov A, Levin M, Tattikota S, Tokalov S, Hoque M, Scherzinger D, Marini F, Poetsch A, Binder H, Macher-Göppinger S, Probst HC, Tian B, Schaefer M, Lackner KJ, Westermann F, Danckwardt S.

Nat Commun. 2018 Dec 14;9(1):5331. doi: 10.1038/s41467-018-07580-5.

4.

Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages.

Bohn T, Rapp S, Luther N, Klein M, Bruehl TJ, Kojima N, Aranda Lopez P, Hahlbrock J, Muth S, Endo S, Pektor S, Brand A, Renner K, Popp V, Gerlach K, Vogel D, Lueckel C, Arnold-Schild D, Pouyssegur J, Kreutz M, Huber M, Koenig J, Weigmann B, Probst HC, von Stebut E, Becker C, Schild H, Schmitt E, Bopp T.

Nat Immunol. 2018 Dec;19(12):1319-1329. doi: 10.1038/s41590-018-0226-8. Epub 2018 Nov 5.

PMID:
30397348
5.

Production of Extracellular Adenosine by CD73+ Dendritic Cells Is Crucial for Induction of Tolerance in Contact Hypersensitivity Reactions.

Silva-Vilches C, Ring S, Schrader J, Clausen BE, Probst HC, Melchior F, Schild H, Enk A, Mahnke K.

J Invest Dermatol. 2019 Mar;139(3):541-551. doi: 10.1016/j.jid.2018.10.016. Epub 2018 Oct 28.

PMID:
30393085
6.

Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses.

Hain T, Melchior F, Kamenjarin N, Muth S, Weslati H, Clausen BE, Mahnke K, Silva-Vilches C, Schütze K, Sohl J, Radsak MP, Bündgen G, Bopp T, Danckwardt S, Schild H, Probst HC.

J Invest Dermatol. 2019 Feb;139(2):422-429. doi: 10.1016/j.jid.2018.08.022. Epub 2018 Oct 6.

PMID:
30296420
7.

Combined immunotherapy: CTLA-4 blockade potentiates anti-tumor response induced by transcutaneous immunization.

Rausch J, Lopez PA, Bialojan A, Denny M, Langguth P, Probst HC, Schild H, Radsak MP.

J Dermatol Sci. 2017 Sep;87(3):300-306. doi: 10.1016/j.jdermsci.2017.06.013. Epub 2017 Jun 16.

PMID:
28666747
8.

Transcutaneous immunization with a novel imiquimod nanoemulsion induces superior T cell responses and virus protection.

Lopez PA, Denny M, Hartmann AK, Alflen A, Probst HC, von Stebut E, Tenzer S, Schild H, Stassen M, Langguth P, Radsak MP.

J Dermatol Sci. 2017 Sep;87(3):252-259. doi: 10.1016/j.jdermsci.2017.06.012. Epub 2017 Jun 16.

PMID:
28655469
9.

Innate Effector-Memory T-Cell Activation Regulates Post-Thrombotic Vein Wall Inflammation and Thrombus Resolution.

Luther N, Shahneh F, Brähler M, Krebs F, Jäckel S, Subramaniam S, Stanger C, Schönfelder T, Kleis-Fischer B, Reinhardt C, Probst HC, Wenzel P, Schäfer K, Becker C.

Circ Res. 2016 Dec 9;119(12):1286-1295. Epub 2016 Oct 5.

PMID:
27707800
10.

IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo.

Scheibe K, Backert I, Wirtz S, Hueber A, Schett G, Vieth M, Probst HC, Bopp T, Neurath MF, Neufert C.

Gut. 2017 May;66(5):823-838. doi: 10.1136/gutjnl-2015-310374. Epub 2016 Jan 18.

PMID:
26783184
11.

Regulatory T cell-derived adenosine induces dendritic cell migration through the Epac-Rap1 pathway.

Ring S, Pushkarevskaya A, Schild H, Probst HC, Jendrossek V, Wirsdörfer F, Ledent C, Robson SC, Enk AH, Mahnke K.

J Immunol. 2015 Apr 15;194(8):3735-44. doi: 10.4049/jimmunol.1401434. Epub 2015 Mar 16.

12.

Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.

Ulges A, Klein M, Reuter S, Gerlitzki B, Hoffmann M, Grebe N, Staudt V, Stergiou N, Bohn T, Brühl TJ, Muth S, Yurugi H, Rajalingam K, Bellinghausen I, Tuettenberg A, Hahn S, Reißig S, Haben I, Zipp F, Waisman A, Probst HC, Beilhack A, Buchou T, Filhol-Cochet O, Boldyreff B, Breloer M, Jonuleit H, Schild H, Schmitt E, Bopp T.

Nat Immunol. 2015 Mar;16(3):267-75. doi: 10.1038/ni.3083. Epub 2015 Jan 19.

PMID:
25599562
13.

Superior in vitro stimulation of human CD8+ T-cells by whole virus versus split virus influenza vaccines.

Halbroth BR, Heil A, Distler E, Dass M, Wagner EM, Plachter B, Probst HC, Strand D, Hartwig UF, Karner A, Aichinger G, Kistner O, Landfester K, Herr W.

PLoS One. 2014 Jul 29;9(7):e103392. doi: 10.1371/journal.pone.0103392. eCollection 2014.

14.

Regulation of the tolerogenic function of steady-state DCs.

Probst HC, Muth S, Schild H.

Eur J Immunol. 2014 Apr;44(4):927-33. doi: 10.1002/eji.201343862. Epub 2014 Mar 20. Review.

15.

A CD40/CD40L feedback loop drives the breakdown of CD8(+) T-cell tolerance following depletion of suppressive CD4(+) T cells.

Muth S, Schütze K, Hain T, Yagita H, Schild H, Probst HC.

Eur J Immunol. 2014 Apr;44(4):1099-107. doi: 10.1002/eji.201343738. Epub 2014 Jan 20.

16.

Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells.

Yogev N, Frommer F, Lukas D, Kautz-Neu K, Karram K, Ielo D, von Stebut E, Probst HC, van den Broek M, Riethmacher D, Birnberg T, Blank T, Reizis B, Korn T, Wiendl H, Jung S, Prinz M, Kurschus FC, Waisman A.

Immunity. 2012 Aug 24;37(2):264-75. doi: 10.1016/j.immuni.2012.05.025. Epub 2012 Aug 16.

17.

Radiotherapy promotes tumor-specific effector CD8+ T cells via dendritic cell activation.

Gupta A, Probst HC, Vuong V, Landshammer A, Muth S, Yagita H, Schwendener R, Pruschy M, Knuth A, van den Broek M.

J Immunol. 2012 Jul 15;189(2):558-66. doi: 10.4049/jimmunol.1200563. Epub 2012 Jun 8.

18.

Release of dendritic cells from cognate CD4+ T-cell recognition results in impaired peripheral tolerance and fatal cytotoxic T-cell mediated autoimmunity.

Muth S, Schütze K, Schild H, Probst HC.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9059-64. doi: 10.1073/pnas.1110620109. Epub 2012 May 21.

19.

Regulatory T cells and IL-10 independently counterregulate cytotoxic T lymphocyte responses induced by transcutaneous immunization.

Stein P, Weber M, Prüfer S, Schmid B, Schmitt E, Probst HC, Waisman A, Langguth P, Schild H, Radsak MP.

PLoS One. 2011;6(11):e27911. doi: 10.1371/journal.pone.0027911. Epub 2011 Nov 16.

20.

p38 MAPK controls prothrombin expression by regulated RNA 3' end processing.

Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Gröne HJ, Schirmacher P, Hentze MW, Kulozik AE.

Mol Cell. 2011 Feb 4;41(3):298-310. doi: 10.1016/j.molcel.2010.12.032.

21.

Tonic T cell signalling and T cell tolerance as opposite effects of self-recognition on dendritic cells.

Garbi N, Hämmerling GJ, Probst HC, van den Broek M.

Curr Opin Immunol. 2010 Oct;22(5):601-8. doi: 10.1016/j.coi.2010.08.007. Epub 2010 Sep 27. Review.

PMID:
20880686
22.

UV exposure boosts transcutaneous immunization and improves tumor immunity: cytotoxic T-cell priming through the skin.

Stein P, Rechtsteiner G, Warger T, Bopp T, Fuhr T, Prüfer S, Probst HC, Stassen M, Langguth P, Schild H, Radsak MP.

J Invest Dermatol. 2011 Jan;131(1):211-9. doi: 10.1038/jid.2010.254. Epub 2010 Aug 26.

23.

Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy.

Krummen M, Balkow S, Shen L, Heinz S, Loquai C, Probst HC, Grabbe S.

J Leukoc Biol. 2010 Jul;88(1):189-99. doi: 10.1189/jlb.0408228. Epub 2010 Apr 1.

PMID:
20360404
24.

Deficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy.

Sato Y, Probst HC, Tatsumi R, Ikeuchi Y, Neuberger MS, Rada C.

J Biol Chem. 2010 Mar 5;285(10):7111-8. doi: 10.1074/jbc.M109.052977. Epub 2009 Dec 17.

25.

FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells.

Schildknecht A, Brauer S, Brenner C, Lahl K, Schild H, Sparwasser T, Probst HC, van den Broek M.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):199-203. doi: 10.1073/pnas.0910620107. Epub 2009 Dec 15.

26.

Antigens expressed by myelinating glia cells induce peripheral cross-tolerance of endogenous CD8+ T cells.

Schildknecht A, Probst HC, McCoy KD, Miescher I, Brenner C, Leone DP, Suter U, Ohashi PS, van den Broek M.

Eur J Immunol. 2009 Jun;39(6):1505-15. doi: 10.1002/eji.200839019.

27.

Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells.

Probst HC, Tschannen K, Odermatt B, Schwendener R, Zinkernagel RM, Van Den Broek M.

Clin Exp Immunol. 2005 Sep;141(3):398-404.

28.

Priming of CTLs by lymphocytic choriomeningitis virus depends on dendritic cells.

Probst HC, van den Broek M.

J Immunol. 2005 Apr 1;174(7):3920-4.

29.

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation.

Lang KS, Recher M, Navarini AA, Harris NL, Löhning M, Junt T, Probst HC, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2005 Mar;35(3):738-45.

30.

Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

Probst HC, McCoy K, Okazaki T, Honjo T, van den Broek M.

Nat Immunol. 2005 Mar;6(3):280-6. Epub 2005 Jan 30.

PMID:
15685176
31.

DC infection promotes antiviral CTL priming: the 'Winkelried' strategy.

Freigang S, Probst HC, van den Broek M.

Trends Immunol. 2005 Jan;26(1):13-8. Review.

PMID:
15629404
32.

Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression.

Probst HC, Tschannen K, Gallimore A, Martinic M, Basler M, Dumrese T, Jones E, van den Broek MF.

J Immunol. 2003 Nov 15;171(10):5415-22.

33.

Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance.

Probst HC, Lagnel J, Kollias G, van den Broek M.

Immunity. 2003 May;18(5):713-20.

34.

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