Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 85


Burkholderia thailandensis strain E555 is a surrogate for the investigation of Burkholderia pseudomallei replication and survival in macrophages.

Kovacs-Simon A, Hemsley CM, Scott AE, Prior JL, Titball RW.

BMC Microbiol. 2019 May 15;19(1):97. doi: 10.1186/s12866-019-1469-8.


Genome Resequencing of Laboratory Stocks of Burkholderia pseudomallei K96243.

Wagley S, Scott AE, Ireland PM, Prior JL, Atkins TP, Bancroft GJ, Studholme DJ, Titball RW.

Microbiol Resour Announc. 2019 Feb 28;8(9). pii: e01529-18. doi: 10.1128/MRA.01529-18. eCollection 2019 Feb.


Calcium carbonate nanoparticles stimulate tumor metabolic reprogramming and modulate tumor metastasis.

Som A, Raliya R, Paranandi K, High RA, Reed N, Beeman SC, Brandenburg M, Sudlow G, Prior JL, Akers W, Mah-Som AY, Habimana-Griffin L, Garbow J, Ippolito JE, Pagel MD, Biswas P, Achilefu S.

Nanomedicine (Lond). 2019 Jan;14(2):169-182. doi: 10.2217/nnm-2018-0302. Epub 2018 Dec 6.


An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia.

Marshall LE, Nelson M, Davies CH, Whelan AO, Jenner DC, Moule MG, Denman C, Cuccui J, Atkins TP, Wren BW, Prior JL.

J Immunol Res. 2018 Nov 29;2018:8087916. doi: 10.1155/2018/8087916. eCollection 2018.


Zoonoses under our noses.

Cross AR, Baldwin VM, Roy S, Essex-Lopresti AE, Prior JL, Harmer NJ.

Microbes Infect. 2019 Jan - Feb;21(1):10-19. doi: 10.1016/j.micinf.2018.06.001. Epub 2018 Jun 18. Review.


An "off-the-shelf" fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies.

Cooper ML, Choi J, Staser K, Ritchey JK, Devenport JM, Eckardt K, Rettig MP, Wang B, Eissenberg LG, Ghobadi A, Gehrs LN, Prior JL, Achilefu S, Miller CA, Fronick CC, O'Neal J, Gao F, Weinstock DM, Gutierrez A, Fulton RS, DiPersio JF.

Leukemia. 2018 Sep;32(9):1970-1983. doi: 10.1038/s41375-018-0065-5. Epub 2018 Feb 20.


Structural characterisation of the capsular polysaccharide expressed by Burkholderia thailandensis strain E555:: wbiI (pKnock-KmR) and assessment of the significance of the 2-O-acetyl group in immune protection.

Bayliss M, Donaldson MI, Nepogodiev SA, Pergolizzi G, Scott AE, Harmer NJ, Field RA, Prior JL.

Carbohydr Res. 2017 Nov 27;452:17-24. doi: 10.1016/j.carres.2017.09.011. Epub 2017 Sep 21.


A new model of multi-visceral and bone metastatic prostate cancer with perivascular niche targeting by a novel endothelial specific adenoviral vector.

Lu ZH, Kaliberov S, Sohn RE, Kaliberova L, Du Y, Prior JL, Leib DJ, Chauchereau A, Sehn JK, Curiel DT, Arbeit JM.

Oncotarget. 2017 Feb 14;8(7):12272-12289. doi: 10.18632/oncotarget.14699.


Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease.

Sundaram GS, Dhavale DD, Prior JL, Yan P, Cirrito J, Rath NP, Laforest R, Cairns NJ, Lee JM, Kotzbauer PT, Sharma V.

Sci Rep. 2016 Nov 2;6:35636. doi: 10.1038/srep35636.


Mapping epigenetic changes to the host cell genome induced by Burkholderia pseudomallei reveals pathogen-specific and pathogen-generic signatures of infection.

Cizmeci D, Dempster EL, Champion OL, Wagley S, Akman OE, Prior JL, Soyer OS, Mill J, Titball RW.

Sci Rep. 2016 Aug 3;6:30861. doi: 10.1038/srep30861.


Gradient-Based Algorithm for Determining Tumor Volumes in Small Animals Using Planar Fluorescence Imaging Platform.

Miller JP, Egbulefu C, Prior JL, Zhou M, Achilefu S.

Tomography. 2016 Mar;2(1):17-25.


Protection against Experimental Melioidosis with a Synthetic manno-Heptopyranose Hexasaccharide Glycoconjugate.

Scott AE, Christ WJ, George AJ, Stokes MG, Lohman GJ, Guo Y, Jones M, Titball RW, Atkins TP, Campbell AS, Prior JL.

Bioconjug Chem. 2016 Jun 15;27(6):1435-46. doi: 10.1021/acs.bioconjchem.5b00525. Epub 2016 May 17.


(67/68)Galmydar: A metalloprobe for monitoring breast cancer resistance protein (BCRP)-mediated functional transport activity.

Sivapackiam J, Harpstrite SE, Prior JL, Mattingly S, Sharma V.

Nucl Med Biol. 2016 Mar;43(3):191-7. doi: 10.1016/j.nucmedbio.2015.12.001. Epub 2015 Dec 8.


Differential Toll-Like Receptor-Signalling of Burkholderia pseudomallei Lipopolysaccharide in Murine and Human Models.

Weehuizen TA, Prior JL, van der Vaart TW, Ngugi SA, Nepogodiev SA, Field RA, Kager LM, van 't Veer C, de Vos AF, Wiersinga WJ.

PLoS One. 2015 Dec 21;10(12):e0145397. doi: 10.1371/journal.pone.0145397. eCollection 2015.


Unraveling the B. pseudomallei Heptokinase WcbL: From Structure to Drug Discovery.

Vivoli M, Isupov MN, Nicholas R, Hill A, Scott AE, Kosma P, Prior JL, Harmer NJ.

Chem Biol. 2015 Dec 17;22(12):1622-32. doi: 10.1016/j.chembiol.2015.10.015.


Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer's disease.

Sundaram GS, Dhavale D, Prior JL, Sivapackiam J, Laforest R, Kotzbauer P, Sharma V.

EJNMMI Res. 2015 Dec;5(1):112. doi: 10.1186/s13550-015-0112-4. Epub 2015 May 24.


Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice, net intracellular replication and a novel protein conferring serum resistance.

Lazar Adler NR, Stevens MP, Dean RE, Saint RJ, Pankhania D, Prior JL, Atkins TP, Kessler B, Nithichanon A, Lertmemongkolchai G, Galyov EE.

PLoS One. 2015 Apr 1;10(4):e0121271. doi: 10.1371/journal.pone.0121271. eCollection 2015.


Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat.

Schwarz JM, Noworolski SM, Wen MJ, Dyachenko A, Prior JL, Weinberg ME, Herraiz LA, Tai VW, Bergeron N, Bersot TP, Rao MN, Schambelan M, Mulligan K.

J Clin Endocrinol Metab. 2015 Jun;100(6):2434-42. doi: 10.1210/jc.2014-3678. Epub 2015 Mar 31.


[(18)F]FHBG PET/CT Imaging of CD34-TK75 Transduced Donor T Cells in Relapsed Allogeneic Stem Cell Transplant Patients: Safety and Feasibility.

Eissenberg LG, Rettig MP, Ritchey JK, Prior JL, Schwarz SW, Frye J, White BS, Fulton RS, Ghobadi A, Cooper ML, Couriel DR, Seegulam ME, Piwnica-Worms D, Dehdashti F, Cornetta K, DiPersio JF.

Mol Ther. 2015 Jun;23(6):1110-1122. doi: 10.1038/mt.2015.48. Epub 2015 Mar 25.


A generator-produced gallium-68 radiopharmaceutical for PET imaging of myocardial perfusion.

Sharma V, Sivapackiam J, Harpstrite SE, Prior JL, Gu H, Rath NP, Piwnica-Worms D.

PLoS One. 2014 Oct 29;9(10):e109361. doi: 10.1371/journal.pone.0109361. eCollection 2014.


Protection against experimental melioidosis following immunisation with a lipopolysaccharide-protein conjugate.

Scott AE, Ngugi SA, Laws TR, Corser D, Lonsdale CL, D'Elia RV, Titball RW, Williamson ED, Atkins TP, Prior JL.

J Immunol Res. 2014;2014:392170. doi: 10.1155/2014/392170. Epub 2014 May 7.


Burkholderia pseudomallei capsular polysaccharide conjugates provide protection against acute melioidosis.

Scott AE, Burtnick MN, Stokes MG, Whelan AO, Williamson ED, Atkins TP, Prior JL, Brett PJ.

Infect Immun. 2014 Aug;82(8):3206-13. doi: 10.1128/IAI.01847-14. Epub 2014 May 27.


Correction: Identification of a Predicted Trimeric Autotransporter Adhesin Required for Biofilm Formation of Burkholderia pseudomallei.

Lazar Adler NR, Dean RE, Saint RJ, Stevens MP, Prior JL, Atkins TP, Galyov EE.

PLoS One. 2014 Jan 9;9(1). doi: 10.1371/annotation/f016476b-5b84-4c9a-899f-fe8b8bc927b5. eCollection 2014.


Identification of a predicted trimeric autotransporter adhesin required for biofilm formation of Burkholderia pseudomallei.

Lazar Adler NR, Dean RE, Saint RJ, Stevens MP, Prior JL, Atkins TP, Galyov EE.

PLoS One. 2013 Nov 5;8(11):e79461. doi: 10.1371/journal.pone.0079461. eCollection 2013. Erratum in: PLoS One. 2014 Jan 9;9(1):.


Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis.

Cuccui J, Thomas RM, Moule MG, D'Elia RV, Laws TR, Mills DC, Williamson D, Atkins TP, Prior JL, Wren BW.

Open Biol. 2013 May 22;3(5):130002. doi: 10.1098/rsob.130002.


Protection against experimental melioidosis following immunization with live Burkholderia thailandensis expressing a manno-heptose capsule.

Scott AE, Laws TR, D'Elia RV, Stokes MG, Nandi T, Williamson ED, Tan P, Prior JL, Atkins TP.

Clin Vaccine Immunol. 2013 Jul;20(7):1041-7. doi: 10.1128/CVI.00113-13. Epub 2013 May 15.


The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis.

Zhang K, Corsa CA, Ponik SM, Prior JL, Piwnica-Worms D, Eliceiri KW, Keely PJ, Longmore GD.

Nat Cell Biol. 2013 Jun;15(6):677-87. doi: 10.1038/ncb2743. Epub 2013 May 5.


Conjugation of Y. pestis F1-antigen to gold nanoparticles improves immunogenicity.

Gregory AE, Williamson ED, Prior JL, Butcher WA, Thompson IJ, Shaw AM, Titball RW.

Vaccine. 2012 Nov 6;30(48):6777-82. doi: 10.1016/j.vaccine.2012.09.021. Epub 2012 Sep 18.


IFNγR signaling mediates alloreactive T-cell trafficking and GVHD.

Choi J, Ziga ED, Ritchey J, Collins L, Prior JL, Cooper ML, Piwnica-Worms D, DiPersio JF.

Blood. 2012 Nov 8;120(19):4093-103. doi: 10.1182/blood-2012-01-403196. Epub 2012 Sep 12.


Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.

Chinault SL, Prior JL, Kaltenbronn KM, Penly A, Weilbaecher KN, Piwnica-Worms D, Blumer KJ.

Clin Cancer Res. 2012 Aug 1;18(15):4136-44. doi: 10.1158/1078-0432.CCR-12-0642. Epub 2012 Jun 12.


Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region.

Cuccui J, Milne TS, Harmer N, George AJ, Harding SV, Dean RE, Scott AE, Sarkar-Tyson M, Wren BW, Titball RW, Prior JL.

Infect Immun. 2012 Mar;80(3):1209-21. doi: 10.1128/IAI.05805-11. Epub 2012 Jan 17.


Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.

Heller E, Hurchla MA, Xiang J, Su X, Chen S, Schneider J, Joeng KS, Vidal M, Goldberg L, Deng H, Hornick MC, Prior JL, Piwnica-Worms D, Long F, Cagan R, Weilbaecher KN.

Cancer Res. 2012 Feb 15;72(4):897-907. doi: 10.1158/0008-5472.CAN-11-2681. Epub 2011 Dec 20.


O-linked glycosylation of the PilA pilin protein of Francisella tularensis: identification of the endogenous protein-targeting oligosaccharyltransferase and characterization of the native oligosaccharide.

Egge-Jacobsen W, Salomonsson EN, Aas FE, Forslund AL, Winther-Larsen HC, Maier J, Macellaro A, Kuoppa K, Oyston PC, Titball RW, Thomas RM, Forsberg Å, Prior JL, Koomey M.

J Bacteriol. 2011 Oct;193(19):5487-97. doi: 10.1128/JB.00383-11. Epub 2011 Jul 29.


Glycosylation of DsbA in Francisella tularensis subsp. tularensis.

Thomas RM, Twine SM, Fulton KM, Tessier L, Kilmury SL, Ding W, Harmer N, Michell SL, Oyston PC, Titball RW, Prior JL.

J Bacteriol. 2011 Oct;193(19):5498-509. doi: 10.1128/JB.00438-11. Epub 2011 Jul 29.


Flagellar glycosylation in Burkholderia pseudomallei and Burkholderia thailandensis.

Scott AE, Twine SM, Fulton KM, Titball RW, Essex-Lopresti AE, Atkins TP, Prior JL.

J Bacteriol. 2011 Jul;193(14):3577-87. doi: 10.1128/JB.01385-10. Epub 2011 May 20.


Development of reagents and assays for the detection of pathogenic Burkholderia species.

Qazi O, Rani M, Gnanam AJ, Cullen TW, Stead CM, Kensing H, McCaul K, Ngugi S, Prior JL, Lipka A, Nagy JM, Gregory CW, Judy BM, Harding SV, Titball RW, Sidhu SS, Trent MS, Kitto GB, Torres A, Estes DM, Iverson B, Georgiou G, Brown KA.

Faraday Discuss. 2011;149:23-36; discussion 63-77.


The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei.

Burtnick MN, Brett PJ, Harding SV, Ngugi SA, Ribot WJ, Chantratita N, Scorpio A, Milne TS, Dean RE, Fritz DL, Peacock SJ, Prior JL, Atkins TP, Deshazer D.

Infect Immun. 2011 Apr;79(4):1512-25. doi: 10.1128/IAI.01218-10. Epub 2011 Feb 7.


Monitoring molecular-specific pharmacodynamics of rapamycin in vivo with inducible Gal4->Fluc transgenic reporter mice.

Pan MH, Lin J, Prior JL, Piwnica-Worms D.

Mol Cancer Ther. 2010 Oct;9(10):2752-60. doi: 10.1158/1535-7163.MCT-10-0265. Epub 2010 Sep 21.


Synthesis, characterization, and molecular structure of a novel zinc (II) complex: assessment of impact of MDR1Pgp expression on its cytotoxic activity.

Harpstrite SE, Prior JL, Sivapackiam J, Collins SD, Rath NP, Sharma V.

Med Chem. 2010 Jul;6(4):191-9.


Lipopolysaccharide from Burkholderia thailandensis E264 provides protection in a murine model of melioidosis.

Ngugi SA, Ventura VV, Qazi O, Harding SV, Kitto GB, Estes DM, Dell A, Titball RW, Atkins TP, Brown KA, Hitchen PG, Prior JL.

Vaccine. 2010 Nov 3;28(47):7551-5. doi: 10.1016/j.vaccine.2010.08.058. Epub 2010 Sep 15.


Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.

Lennerz JK, Hurov JB, White LS, Lewandowski KT, Prior JL, Planer GJ, Gereau RW 4th, Piwnica-Worms D, Schmidt RE, Piwnica-Worms H.

Mol Cell Biol. 2010 Nov;30(21):5043-56. doi: 10.1128/MCB.01472-09. Epub 2010 Aug 23.


Deletion of the Bacillus anthracis capB homologue in Francisella tularensis subspecies tularensis generates an attenuated strain that protects mice against virulent tularaemia.

Michell SL, Dean RE, Eyles JE, Hartley MG, Waters E, Prior JL, Titball RW, Oyston PC.

J Med Microbiol. 2010 Nov;59(Pt 11):1275-84. doi: 10.1099/jmm.0.018911-0. Epub 2010 Jul 22.


Synthesis, molecular structure, and validation of metalloprobes for assessment of MDR1 P-glycoprotein-mediated functional transport.

Sivapackiam J, Harpstrite SE, Prior JL, Gu H, Rath NP, Sharma V.

Dalton Trans. 2010 Jul 7;39(25):5842-50. doi: 10.1039/c002361b. Epub 2010 May 27.


In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.

Choi J, Ritchey J, Prior JL, Holt M, Shannon WD, Deych E, Piwnica-Worms DR, DiPersio JF.

Blood. 2010 Jul 8;116(1):129-39. doi: 10.1182/blood-2009-12-257253. Epub 2010 Apr 27.


Dissection of platelet and myeloid cell defects by conditional targeting of the beta3-integrin subunit.

Morgan EA, Schneider JG, Baroni TE, Uluçkan O, Heller E, Hurchla MA, Deng H, Floyd D, Berdy A, Prior JL, Piwnica-Worms D, Teitelbaum SL, Ross FP, Weilbaecher KN.

FASEB J. 2010 Apr;24(4):1117-27. doi: 10.1096/fj.09-138420. Epub 2009 Nov 20.


The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts.

Hirbe AC, Roelofs AJ, Floyd DH, Deng H, Becker SN, Lanigan LG, Apicelli AJ, Xu Z, Prior JL, Eagleton MC, Piwnica-Worms D, Rogers MJ, Weilbaecher K.

Bone. 2009 May;44(5):908-16. doi: 10.1016/j.bone.2009.01.010. Epub 2009 Jan 23.


CD47 regulates bone mass and tumor metastasis to bone.

Uluçkan O, Becker SN, Deng H, Zou W, Prior JL, Piwnica-Worms D, Frazier WA, Weilbaecher KN.

Cancer Res. 2009 Apr 1;69(7):3196-204. doi: 10.1158/0008-5472.CAN-08-3358. Epub 2009 Mar 10.


Senescent stromal-derived osteopontin promotes preneoplastic cell growth.

Pazolli E, Luo X, Brehm S, Carbery K, Chung JJ, Prior JL, Doherty J, Demehri S, Salavaggione L, Piwnica-Worms D, Stewart SA.

Cancer Res. 2009 Feb 1;69(3):1230-9. doi: 10.1158/0008-5472.CAN-08-2970. Epub 2009 Jan 20.


Sero-characterization of lipopolysaccharide from Burkholderia thailandensis.

Qazi O, Prior JL, Judy BM, Whitlock GC, Kitto GB, Torres AG, Estes DM, Brown KA.

Trans R Soc Trop Med Hyg. 2008 Dec;102 Suppl 1:S58-60. doi: 10.1016/S0035-9203(08)70016-6.


Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

Nervi B, Ramirez P, Rettig MP, Uy GL, Holt MS, Ritchey JK, Prior JL, Piwnica-Worms D, Bridger G, Ley TJ, DiPersio JF.

Blood. 2009 Jun 11;113(24):6206-14. doi: 10.1182/blood-2008-06-162123. Epub 2008 Dec 2.

Supplemental Content

Loading ...
Support Center