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Items: 1 to 50 of 81

1.

Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells.

Sandrock I, Reinhardt A, Ravens S, Binz C, Wilharm A, Martins J, Oberdörfer L, Tan L, Lienenklaus S, Zhang B, Naumann R, Zhuang Y, Krueger A, Förster R, Prinz I.

J Exp Med. 2018 Dec 3;215(12):3006-3018. doi: 10.1084/jem.20181439. Epub 2018 Nov 19.

PMID:
30455268
2.

Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease.

Schultze-Florey RE, Tischer S, Kuhlmann L, Hundsdoerfer P, Koch A, Anagnostopoulos I, Ravens S, Goudeva L, Schultze-Florey C, Koenecke C, Blasczyk R, Koehl U, Heuft HG, Prinz I, Eiz-Vesper B, Maecker-Kolhoff B.

Front Immunol. 2018 Jun 27;9:1475. doi: 10.3389/fimmu.2018.01475. eCollection 2018.

3.

BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells.

Lessel D, Gehbauer C, Bramswig NC, Schluth-Bolard C, Venkataramanappa S, van Gassen KLI, Hempel M, Haack TB, Baresic A, Genetti CA, Funari MFA, Lessel I, Kuhlmann L, Simon R, Liu P, Denecke J, Kuechler A, de Kruijff I, Shoukier M, Lek M, Mullen T, Lüdecke HJ, Lerario AM, Kobbe R, Krieger T, Demeer B, Lebrun M, Keren B, Nava C, Buratti J, Afenjar A, Shinawi M, Guillen Sacoto MJ, Gauthier J, Hamdan FF, Laberge AM, Campeau PM, Louie RJ, Cathey SS, Prinz I, Jorge AAL, Terhal PA, Lenhard B, Wieczorek D, Strom TM, Agrawal PB, Britsch S, Tolosa E, Kubisch C.

Brain. 2018 Jul 9. doi: 10.1093/brain/awy173. [Epub ahead of print]

PMID:
29985992
4.
5.

[Mutual influence of immune system and bones].

Kamradt T, Amling M, Dankbar B, Dudeck A, Gunzer M, Ignatius A, Krönke G, Kubatzky K, Pap T, Prinz I, Schett G, Schinke T, Tuckermann J, Waisman A.

Z Rheumatol. 2018 May;77(Suppl 1):8-11. doi: 10.1007/s00393-018-0454-1. Review. German. No abstract available.

PMID:
29675686
6.

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.

Hammer Q, Rückert T, Borst EM, Dunst J, Haubner A, Durek P, Heinrich F, Gasparoni G, Babic M, Tomic A, Pietra G, Nienen M, Blau IW, Hofmann J, Na IK, Prinz I, Koenecke C, Hemmati P, Babel N, Arnold R, Walter J, Thurley K, Mashreghi MF, Messerle M, Romagnani C.

Nat Immunol. 2018 May;19(5):453-463. doi: 10.1038/s41590-018-0082-6. Epub 2018 Apr 9.

PMID:
29632329
7.

Human γδ T Cell Receptor Repertoires in Peripheral Blood Remain Stable Despite Clearance of Persistent Hepatitis C Virus Infection by Direct-Acting Antiviral Drug Therapy.

Ravens S, Hengst J, Schlapphoff V, Deterding K, Dhingra A, Schultze-Florey C, Koenecke C, Cornberg M, Wedemeyer H, Prinz I.

Front Immunol. 2018 Mar 16;9:510. doi: 10.3389/fimmu.2018.00510. eCollection 2018.

8.

IL-17-Mediated Immunity Controls Skin Infection and T Helper 1 Response during Experimental Microsporum canis Dermatophytosis.

Burstein VL, Guasconi L, Beccacece I, Theumer MG, Mena C, Prinz I, Cervi L, Herrero M, Masih DT, Chiapello LS.

J Invest Dermatol. 2018 Aug;138(8):1744-1753. doi: 10.1016/j.jid.2018.02.042. Epub 2018 Mar 20.

PMID:
29571944
9.

Publisher Correction: Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection.

Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdörfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Förster R, Koenecke C, Prinz I.

Nat Immunol. 2018 Sep;19(9):1037. doi: 10.1038/s41590-018-0054-x.

PMID:
29449629
10.

The neonatal window of opportunity-early priming for life.

Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J, Ghazal P, Hackam DJ, Marsland BJ, McCoy KD, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser JN, Wesemann DR, Hornef MW.

J Allergy Clin Immunol. 2018 Apr;141(4):1212-1214. doi: 10.1016/j.jaci.2017.11.019. Epub 2017 Dec 14. No abstract available.

11.

Innately versatile: γδ17 T cells in inflammatory and autoimmune diseases.

Papotto PH, Reinhardt A, Prinz I, Silva-Santos B.

J Autoimmun. 2018 Feb;87:26-37. doi: 10.1016/j.jaut.2017.11.006. Epub 2017 Dec 6. Review.

12.

IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation.

Alnahas S, Hagner S, Raifer H, Kilic A, Gasteiger G, Mutters R, Hellhund A, Prinz I, Pinkenburg O, Visekruna A, Garn H, Steinhoff U.

Front Immunol. 2017 Nov 14;8:1562. doi: 10.3389/fimmu.2017.01562. eCollection 2017.

13.

Pathogenic TH17 inflammation is sustained in the lungs by conventional dendritic cells and Toll-like receptor 4 signaling.

Shalaby KH, Lyons-Cohen MR, Whitehead GS, Thomas SY, Prinz I, Nakano H, Cook DN.

J Allergy Clin Immunol. 2018 Oct;142(4):1229-1242.e6. doi: 10.1016/j.jaci.2017.10.023. Epub 2017 Nov 14.

14.

Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7.

Vachharajani N, Joeris T, Luu M, Hartmann S, Pautz S, Jenike E, Pantazis G, Prinz I, Hofer MJ, Steinhoff U, Visekruna A.

Oncotarget. 2017 Jan 10;8(31):50447-50459. doi: 10.18632/oncotarget.14579. eCollection 2017 Aug 1.

15.

The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability.

Edelblum KL, Sharon G, Singh G, Odenwald MA, Sailer A, Cao S, Ravens S, Thomsen I, El Bissati K, McLeod R, Dong C, Gurbuxani S, Prinz I, Mazmanian SK, Turner JR.

Cell Mol Gastroenterol Hepatol. 2017 Jun 10;4(2):285-297. doi: 10.1016/j.jcmgh.2017.06.001. eCollection 2017 Sep.

16.

CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke.

Arunachalam P, Ludewig P, Melich P, Arumugam TV, Gerloff C, Prinz I, Magnus T, Gelderblom M.

Stroke. 2017 Jul;48(7):1957-1965. doi: 10.1161/STROKEAHA.117.016753. Epub 2017 Jun 13.

PMID:
28611085
17.

Eomes expression reports the progressive differentiation of IFN-γ-producing Th1-like γδ T cells.

Lino CNR, Barros-Martins J, Oberdörfer L, Walzer T, Prinz I.

Eur J Immunol. 2017 Jun;47(6):970-981. doi: 10.1002/eji.201646753. Epub 2017 Apr 24.

18.

Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection.

Pezoldt J, Pisano F, Heine W, Pasztoi M, Rosenheinrich M, Nuss AM, Pils MC, Prinz I, Förster R, Huehn J, Dersch P.

J Infect Dis. 2017 Sep 15;216(6):752-760. doi: 10.1093/infdis/jix037.

PMID:
28329174
19.

Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection.

Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdörfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Förster R, Koenecke C, Prinz I.

Nat Immunol. 2017 Apr;18(4):393-401. doi: 10.1038/ni.3686. Epub 2017 Feb 20. Erratum in: Nat Immunol. 2018 Feb 14;:.

PMID:
28218745
20.

Reply.

Reinhardt A, Prinz I.

Arthritis Rheumatol. 2017 Jun;69(6):1339-1341. doi: 10.1002/art.40050. No abstract available.

21.

Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections.

Hassane M, Demon D, Soulard D, Fontaine J, Keller LE, Patin EC, Porte R, Prinz I, Ryffel B, Kadioglu A, Veening JW, Sirard JC, Faveeuw C, Lamkanfi M, Trottein F, Paget C.

Mucosal Immunol. 2017 Jul;10(4):1056-1068. doi: 10.1038/mi.2016.113. Epub 2017 Jan 4.

PMID:
28051086
22.

Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease.

Raha S, Raud B, Oberdörfer L, Castro CN, Schreder A, Freitag J, Longerich T, Lochner M, Sparwasser T, Berod L, Koenecke C, Prinz I.

Eur J Immunol. 2016 Sep;46(9):2233-8. doi: 10.1002/eji.201546152. Epub 2016 Jul 18.

23.

Interleukin-23-Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice.

Reinhardt A, Yevsa T, Worbs T, Lienenklaus S, Sandrock I, Oberdörfer L, Korn T, Weiss S, Förster R, Prinz I.

Arthritis Rheumatol. 2016 Oct;68(10):2476-86. doi: 10.1002/art.39732.

24.

IL-17 is not essential for inflammation and chronic pelvic pain development in an experimental model of chronic prostatitis/chronic pelvic pain syndrome.

Motrich RD, Breser ML, Sánchez LR, Godoy GJ, Prinz I, Rivero VE.

Pain. 2016 Mar;157(3):585-97. doi: 10.1097/j.pain.0000000000000405.

PMID:
26882345
25.

Brief Report: Arthritis in KRN T Cell Receptor-Transgenic Mice Does Not Require Interleukin-17 or Th17 Cells.

Auger JL, Cowan HM, Engelson BJ, Kashem SW, Prinz I, Binstadt BA.

Arthritis Rheumatol. 2016 Aug;68(8):1849-55. doi: 10.1002/art.39646.

26.

Corrigendum: Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes Are More Innate Than Others.

Vermijlen D, Prinz I.

Front Immunol. 2015 Dec 14;6:624. doi: 10.3389/fimmu.2015.00624. eCollection 2015.

27.

MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development.

Sandrock I, Ziętara N, Łyszkiewicz M, Oberdörfer L, Witzlau K, Krueger A, Prinz I.

PLoS One. 2015 Dec 16;10(12):e0145010. doi: 10.1371/journal.pone.0145010. eCollection 2015.

28.

Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients.

Klemann C, Schröder A, Dreier A, Möhn N, Dippel S, Winterberg T, Wilde A, Yu Y, Thorenz A, Gueler F, Jörns A, Tolosa E, Leonhardt J, Haas JD, Prinz I, Vieten G, Petersen C, Kuebler JF.

Gastroenterology. 2016 Jan;150(1):229-241.e5. doi: 10.1053/j.gastro.2015.09.008. Epub 2015 Sep 25.

PMID:
26404950
29.

γδ T cells come to stay: Innate skin memory in the Aldara model.

Prinz I, Sandrock I.

Eur J Immunol. 2015 Nov;45(11):2994-7. doi: 10.1002/eji.201546033. Epub 2015 Oct 12.

30.

Multicongenic fate mapping quantification of dynamics of thymus colonization.

Ziętara N, Łyszkiewicz M, Puchałka J, Witzlau K, Reinhardt A, Förster R, Pabst O, Prinz I, Krueger A.

J Exp Med. 2015 Sep 21;212(10):1589-601. doi: 10.1084/jem.20142143. Epub 2015 Sep 7.

31.

Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.

Yang BH, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, Föhse L, Prinz I, Pezoldt J, Suerbaum S, Sparwasser T, Hamann A, Floess S, Huehn J, Lochner M.

Mucosal Immunol. 2016 Mar;9(2):444-57. doi: 10.1038/mi.2015.74. Epub 2015 Aug 26.

PMID:
26307665
32.

A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6⁺CD27⁻ subset.

Kashani E, Föhse L, Raha S, Sandrock I, Oberdörfer L, Koenecke C, Suerbaum S, Weiss S, Prinz I.

Nat Commun. 2015 Mar 13;6:6477. doi: 10.1038/ncomms7477.

PMID:
25765849
33.

Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis.

Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse AW, Herkel J, Schramm C.

J Immunol. 2015 Mar 15;194(6):2522-30. doi: 10.4049/jimmunol.1400076. Epub 2015 Feb 11.

34.

Limited niche availability suppresses murine intrathymic dendritic-cell development from noncommitted progenitors.

Łyszkiewicz M, Ziętara N, Föhse L, Puchałka J, Diestelhorst J, Witzlau K, Prinz I, Schambach A, Krueger A.

Blood. 2015 Jan 15;125(3):457-64. doi: 10.1182/blood-2014-07-592667. Epub 2014 Nov 19.

35.

Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes are More Innate than Others.

Vermijlen D, Prinz I.

Front Immunol. 2014 Oct 10;5:486. doi: 10.3389/fimmu.2014.00486. eCollection 2014. Review. Erratum in: Front Immunol. 2015;6:624.

36.

γδ T cell subsets play opposing roles in regulating experimental autoimmune encephalomyelitis.

Blink SE, Caldis MW, Goings GE, Harp CT, Malissen B, Prinz I, Xu D, Miller SD.

Cell Immunol. 2014 Jul;290(1):39-51. doi: 10.1016/j.cellimm.2014.04.013. Epub 2014 May 10.

37.

IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs.

Fleige H, Ravens S, Moschovakis GL, Bölter J, Willenzon S, Sutter G, Häussler S, Kalinke U, Prinz I, Förster R.

J Exp Med. 2014 Apr 7;211(4):643-51. doi: 10.1084/jem.20131737. Epub 2014 Mar 24.

38.

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow.

Daussy C, Faure F, Mayol K, Viel S, Gasteiger G, Charrier E, Bienvenu J, Henry T, Debien E, Hasan UA, Marvel J, Yoh K, Takahashi S, Prinz I, de Bernard S, Buffat L, Walzer T.

J Exp Med. 2014 Mar 10;211(3):563-77. doi: 10.1084/jem.20131560. Epub 2014 Feb 10.

39.

CCR7-mediated migration in the thymus controls γδ T-cell development.

Reinhardt A, Ravens S, Fleige H, Haas JD, Oberdörfer L, Łyszkiewicz M, Förster R, Prinz I.

Eur J Immunol. 2014 May;44(5):1320-9. doi: 10.1002/eji.201344330. Epub 2014 Mar 7.

40.

Visualization and quantification of monoallelic TCRα gene rearrangement in αβ T cells.

Winter M, Kashani E, Chennupati V, Föhse L, Prinz I.

Immunol Cell Biol. 2014 May-Jun;92(5):409-16. doi: 10.1038/icb.2013.105. Epub 2014 Jan 14.

PMID:
24418818
41.

Induced and thymus-derived Foxp3⁺ regulatory T cells share a common niche.

Huang YJ, Haist V, Baumgärtner W, Föhse L, Prinz I, Suerbaum S, Floess S, Huehn J.

Eur J Immunol. 2014 Feb;44(2):460-8. doi: 10.1002/eji.201343463. Epub 2013 Oct 30.

42.

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis.

Hammerich L, Bangen JM, Govaere O, Zimmermann HW, Gassler N, Huss S, Liedtke C, Prinz I, Lira SA, Luedde T, Roskams T, Trautwein C, Heymann F, Tacke F.

Hepatology. 2014 Feb;59(2):630-42. doi: 10.1002/hep.26697. Epub 2013 Dec 23.

43.

Functional development of γδ T cells.

Prinz I, Silva-Santos B, Pennington DJ.

Eur J Immunol. 2013 Aug;43(8):1988-94. doi: 10.1002/eji.201343759. Review.

44.

Differential postselection proliferation dynamics of αβ T cells, Foxp3+ regulatory T cells, and invariant NKT cells monitored by genetic pulse labeling.

Föhse L, Reinhardt A, Oberdörfer L, Schmitz S, Förster R, Malissen B, Prinz I.

J Immunol. 2013 Sep 1;191(5):2384-92. doi: 10.4049/jimmunol.1301359. Epub 2013 Jul 26.

45.

Donor Vδ1+ γδ T cells expand after allogeneic hematopoietic stem cell transplantation and show reactivity against CMV-infected cells but not against progressing B-CLL.

Prinz I, Thamm K, Port M, Weissinger EM, Stadler M, Gabaev I, Jacobs R, Ganser A, Koenecke C.

Exp Hematol Oncol. 2013 May 11;2(1):14. doi: 10.1186/2162-3619-2-14.

46.

Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells.

Ziętara N, Łyszkiewicz M, Witzlau K, Naumann R, Hurwitz R, Langemeier J, Bohne J, Sandrock I, Ballmaier M, Weiss S, Prinz I, Krueger A.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7407-12. doi: 10.1073/pnas.1221984110. Epub 2013 Apr 15.

47.

The natural and the inducible: interleukin (IL)-17-producing γδ T cells.

Chien YH, Zeng X, Prinz I.

Trends Immunol. 2013 Apr;34(4):151-4. doi: 10.1016/j.it.2012.11.004. Epub 2012 Dec 22. Review.

48.

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.

Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam TV, Leypoldt F, Simova O, Thom V, Friese MA, Prinz I, Hölscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T.

Blood. 2012 Nov 1;120(18):3793-802. doi: 10.1182/blood-2012-02-412726. Epub 2012 Sep 13.

49.

IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease.

Koenecke C, Lee CW, Thamm K, Föhse L, Schafferus M, Mittrücker HW, Floess S, Huehn J, Ganser A, Förster R, Prinz I.

J Immunol. 2012 Sep 15;189(6):2890-6. doi: 10.4049/jimmunol.1200413. Epub 2012 Aug 6.

50.

IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.

Turner JE, Krebs C, Tittel AP, Paust HJ, Meyer-Schwesinger C, Bennstein SB, Steinmetz OM, Prinz I, Magnus T, Korn T, Stahl RA, Kurts C, Panzer U.

J Am Soc Nephrol. 2012 Sep;23(9):1486-95. doi: 10.1681/ASN.2012010040. Epub 2012 Jul 12.

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