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Items: 1 to 50 of 94

1.

Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy.

Soon CF, Zhang S, Suneetha PV, Antunes DA, Manns MP, Raha S, Schultze-Florey C, Prinz I, Wedemeyer H, Sällberg Chen M, Cornberg M.

Front Immunol. 2019 Sep 4;10:2076. doi: 10.3389/fimmu.2019.02076. eCollection 2019.

2.

Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies.

Sebestyen Z, Prinz I, Déchanet-Merville J, Silva-Santos B, Kuball J.

Nat Rev Drug Discov. 2019 Sep 6. doi: 10.1038/s41573-019-0038-z. [Epub ahead of print] Review.

PMID:
31492944
3.

Dangerous γδ T cells in aged mice.

Prinz I, Sandrock I.

EMBO Rep. 2019 Aug;20(8):e48678. doi: 10.15252/embr.201948678. Epub 2019 Jul 9.

PMID:
31286651
4.

Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells.

Tan L, Sandrock I, Odak I, Aizenbud Y, Wilharm A, Barros-Martins J, Tabib Y, Borchers A, Amado T, Gangoda L, Herold MJ, Schmidt-Supprian M, Kisielow J, Silva-Santos B, Koenecke C, Hovav AH, Krebs C, Prinz I, Ravens S.

Cell Rep. 2019 Jun 18;27(12):3657-3671.e4. doi: 10.1016/j.celrep.2019.05.064.

5.

Focusing of the regulatory T cell repertoire after allogeneic stem cell transplantation indicates protection from graft-versus-host disease.

Odak I, Raha S, Schultze-Florey C, Tavil S, Ravens S, Ganser A, Förster R, Prinz I, Koenecke C.

Haematologica. 2019 Apr 24. pii: haematol.2019.218206. doi: 10.3324/haematol.2019.218206. [Epub ahead of print]

6.

Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads.

Mangare C, Tischer-Zimmermann S, Riese SB, Dragon AC, Prinz I, Blasczyk R, Maecker-Kolhoff B, Eiz-Vesper B.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1415. doi: 10.3390/ijms20061415.

7.

Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells.

Di Lorenzo B, Simões AE, Caiado F, Tieppo P, Correia DV, Carvalho T, da Silva MG, Déchanet-Merville J, Schumacher TN, Prinz I, Norell H, Ravens S, Vermijlen D, Silva-Santos B.

Cancer Immunol Res. 2019 Apr;7(4):552-558. doi: 10.1158/2326-6066.CIR-18-0647. Epub 2019 Mar 20.

PMID:
30894378
8.

The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation.

Sparber F, De Gregorio C, Steckholzer S, Ferreira FM, Dolowschiak T, Ruchti F, Kirchner FR, Mertens S, Prinz I, Joller N, Buch T, Glatz M, Sallusto F, LeibundGut-Landmann S.

Cell Host Microbe. 2019 Mar 13;25(3):389-403.e6. doi: 10.1016/j.chom.2019.02.002.

PMID:
30870621
9.

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.

Łyszkiewicz M, Winter SJ, Witzlau K, Föhse L, Brownlie R, Puchałka J, Verheyden NA, Kunze-Schumacher H, Imelmann E, Blume J, Raha S, Sekiya T, Yoshimura A, Frueh JT, Ullrich E, Huehn J, Weiss S, Gutierrez MG, Prinz I, Zamoyska R, Ziętara N, Krueger A.

PLoS Biol. 2019 Mar 11;17(3):e2006716. doi: 10.1371/journal.pbio.2006716. eCollection 2019 Mar.

10.

Styk1 is specifically expressed in NK1.1+ lymphocytes including NK, γδ T, and iNKT cells in mice, but is dispensable for their ontogeny and function.

Wilharm A, Sandrock I, Marotel M, Demera A, Naumann R, Walzer T, Prinz I.

Eur J Immunol. 2019 May;49(5):686-693. doi: 10.1002/eji.201848033. Epub 2019 Feb 18.

PMID:
30758858
11.

A Fast and Simple Contact Printing Approach to Generate 2D Protein Nanopatterns.

Lindner M, Tresztenyak A, Fülöp G, Jahr W, Prinz A, Prinz I, Danzl JG, Schütz GJ, Sevcsik E.

Front Chem. 2019 Jan 24;6:655. doi: 10.3389/fchem.2018.00655. eCollection 2018.

12.

Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis.

Wilharm A, Tabib Y, Nassar M, Reinhardt A, Mizraji G, Sandrock I, Heyman O, Barros-Martins J, Aizenbud Y, Khalaileh A, Eli-Berchoer L, Elinav E, Wilensky A, Förster R, Bercovier H, Prinz I, Hovav AH.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2652-2661. doi: 10.1073/pnas.1818812116. Epub 2019 Jan 28.

13.

Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3.

Ronkina N, Schuster-Gossler K, Hansmann F, Kunze-Schumacher H, Sandrock I, Yakovleva T, Lafera J, Baumgärtner W, Krueger A, Prinz I, Gossler A, Kotlyarov A, Gaestel M.

Mol Cell Biol. 2019 Mar 1;39(6). pii: e00516-18. doi: 10.1128/MCB.00516-18. Print 2019 Mar 15.

14.

Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells.

Sandrock I, Reinhardt A, Ravens S, Binz C, Wilharm A, Martins J, Oberdörfer L, Tan L, Lienenklaus S, Zhang B, Naumann R, Zhuang Y, Krueger A, Förster R, Prinz I.

J Exp Med. 2018 Dec 3;215(12):3006-3018. doi: 10.1084/jem.20181439. Epub 2018 Nov 19.

15.

Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease.

Schultze-Florey RE, Tischer S, Kuhlmann L, Hundsdoerfer P, Koch A, Anagnostopoulos I, Ravens S, Goudeva L, Schultze-Florey C, Koenecke C, Blasczyk R, Koehl U, Heuft HG, Prinz I, Eiz-Vesper B, Maecker-Kolhoff B.

Front Immunol. 2018 Jun 27;9:1475. doi: 10.3389/fimmu.2018.01475. eCollection 2018.

16.

BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells.

Lessel D, Gehbauer C, Bramswig NC, Schluth-Bolard C, Venkataramanappa S, van Gassen KLI, Hempel M, Haack TB, Baresic A, Genetti CA, Funari MFA, Lessel I, Kuhlmann L, Simon R, Liu P, Denecke J, Kuechler A, de Kruijff I, Shoukier M, Lek M, Mullen T, Lüdecke HJ, Lerario AM, Kobbe R, Krieger T, Demeer B, Lebrun M, Keren B, Nava C, Buratti J, Afenjar A, Shinawi M, Guillen Sacoto MJ, Gauthier J, Hamdan FF, Laberge AM, Campeau PM, Louie RJ, Cathey SS, Prinz I, Jorge AAL, Terhal PA, Lenhard B, Wieczorek D, Strom TM, Agrawal PB, Britsch S, Tolosa E, Kubisch C.

Brain. 2018 Aug 1;141(8):2299-2311. doi: 10.1093/brain/awy173.

17.
18.

[Mutual influence of immune system and bones].

Kamradt T, Amling M, Dankbar B, Dudeck A, Gunzer M, Ignatius A, Krönke G, Kubatzky K, Pap T, Prinz I, Schett G, Schinke T, Tuckermann J, Waisman A.

Z Rheumatol. 2018 May;77(Suppl 1):8-11. doi: 10.1007/s00393-018-0454-1. Review. German. No abstract available.

PMID:
29675686
19.

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.

Hammer Q, Rückert T, Borst EM, Dunst J, Haubner A, Durek P, Heinrich F, Gasparoni G, Babic M, Tomic A, Pietra G, Nienen M, Blau IW, Hofmann J, Na IK, Prinz I, Koenecke C, Hemmati P, Babel N, Arnold R, Walter J, Thurley K, Mashreghi MF, Messerle M, Romagnani C.

Nat Immunol. 2018 May;19(5):453-463. doi: 10.1038/s41590-018-0082-6. Epub 2018 Apr 9.

PMID:
29632329
20.

Human γδ T Cell Receptor Repertoires in Peripheral Blood Remain Stable Despite Clearance of Persistent Hepatitis C Virus Infection by Direct-Acting Antiviral Drug Therapy.

Ravens S, Hengst J, Schlapphoff V, Deterding K, Dhingra A, Schultze-Florey C, Koenecke C, Cornberg M, Wedemeyer H, Prinz I.

Front Immunol. 2018 Mar 16;9:510. doi: 10.3389/fimmu.2018.00510. eCollection 2018.

21.

IL-17-Mediated Immunity Controls Skin Infection and T Helper 1 Response during Experimental Microsporum canis Dermatophytosis.

Burstein VL, Guasconi L, Beccacece I, Theumer MG, Mena C, Prinz I, Cervi L, Herrero M, Masih DT, Chiapello LS.

J Invest Dermatol. 2018 Aug;138(8):1744-1753. doi: 10.1016/j.jid.2018.02.042. Epub 2018 Mar 20.

22.

Publisher Correction: Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection.

Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdörfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Förster R, Koenecke C, Prinz I.

Nat Immunol. 2018 Sep;19(9):1037. doi: 10.1038/s41590-018-0054-x.

PMID:
29449629
23.

The neonatal window of opportunity-early priming for life.

Renz H, Adkins BD, Bartfeld S, Blumberg RS, Farber DL, Garssen J, Ghazal P, Hackam DJ, Marsland BJ, McCoy KD, Penders J, Prinz I, Verhasselt V, von Mutius E, Weiser JN, Wesemann DR, Hornef MW.

J Allergy Clin Immunol. 2018 Apr;141(4):1212-1214. doi: 10.1016/j.jaci.2017.11.019. Epub 2017 Dec 14. No abstract available.

24.

Innately versatile: γδ17 T cells in inflammatory and autoimmune diseases.

Papotto PH, Reinhardt A, Prinz I, Silva-Santos B.

J Autoimmun. 2018 Feb;87:26-37. doi: 10.1016/j.jaut.2017.11.006. Epub 2017 Dec 6. Review.

25.

IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation.

Alnahas S, Hagner S, Raifer H, Kilic A, Gasteiger G, Mutters R, Hellhund A, Prinz I, Pinkenburg O, Visekruna A, Garn H, Steinhoff U.

Front Immunol. 2017 Nov 14;8:1562. doi: 10.3389/fimmu.2017.01562. eCollection 2017.

26.

Pathogenic TH17 inflammation is sustained in the lungs by conventional dendritic cells and Toll-like receptor 4 signaling.

Shalaby KH, Lyons-Cohen MR, Whitehead GS, Thomas SY, Prinz I, Nakano H, Cook DN.

J Allergy Clin Immunol. 2018 Oct;142(4):1229-1242.e6. doi: 10.1016/j.jaci.2017.10.023. Epub 2017 Nov 14.

27.

Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7.

Vachharajani N, Joeris T, Luu M, Hartmann S, Pautz S, Jenike E, Pantazis G, Prinz I, Hofer MJ, Steinhoff U, Visekruna A.

Oncotarget. 2017 Jan 10;8(31):50447-50459. doi: 10.18632/oncotarget.14579. eCollection 2017 Aug 1.

28.

The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability.

Edelblum KL, Sharon G, Singh G, Odenwald MA, Sailer A, Cao S, Ravens S, Thomsen I, El Bissati K, McLeod R, Dong C, Gurbuxani S, Prinz I, Mazmanian SK, Turner JR.

Cell Mol Gastroenterol Hepatol. 2017 Jun 10;4(2):285-297. doi: 10.1016/j.jcmgh.2017.06.001. eCollection 2017 Sep.

29.

CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke.

Arunachalam P, Ludewig P, Melich P, Arumugam TV, Gerloff C, Prinz I, Magnus T, Gelderblom M.

Stroke. 2017 Jul;48(7):1957-1965. doi: 10.1161/STROKEAHA.117.016753. Epub 2017 Jun 13.

PMID:
28611085
30.

Eomes expression reports the progressive differentiation of IFN-γ-producing Th1-like γδ T cells.

Lino CNR, Barros-Martins J, Oberdörfer L, Walzer T, Prinz I.

Eur J Immunol. 2017 Jun;47(6):970-981. doi: 10.1002/eji.201646753. Epub 2017 Apr 24.

31.

Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection.

Pezoldt J, Pisano F, Heine W, Pasztoi M, Rosenheinrich M, Nuss AM, Pils MC, Prinz I, Förster R, Huehn J, Dersch P.

J Infect Dis. 2017 Sep 15;216(6):752-760. doi: 10.1093/infdis/jix037.

PMID:
28329174
32.

Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection.

Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdörfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Förster R, Koenecke C, Prinz I.

Nat Immunol. 2017 Apr;18(4):393-401. doi: 10.1038/ni.3686. Epub 2017 Feb 20. Erratum in: Nat Immunol. 2018 Feb 14;:.

PMID:
28218745
33.

Reply.

Reinhardt A, Prinz I.

Arthritis Rheumatol. 2017 Jun;69(6):1339-1341. doi: 10.1002/art.40050. No abstract available.

34.

Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections.

Hassane M, Demon D, Soulard D, Fontaine J, Keller LE, Patin EC, Porte R, Prinz I, Ryffel B, Kadioglu A, Veening JW, Sirard JC, Faveeuw C, Lamkanfi M, Trottein F, Paget C.

Mucosal Immunol. 2017 Jul;10(4):1056-1068. doi: 10.1038/mi.2016.113. Epub 2017 Jan 4.

PMID:
28051086
35.

Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease.

Raha S, Raud B, Oberdörfer L, Castro CN, Schreder A, Freitag J, Longerich T, Lochner M, Sparwasser T, Berod L, Koenecke C, Prinz I.

Eur J Immunol. 2016 Sep;46(9):2233-8. doi: 10.1002/eji.201546152. Epub 2016 Jul 18.

36.

Interleukin-23-Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice.

Reinhardt A, Yevsa T, Worbs T, Lienenklaus S, Sandrock I, Oberdörfer L, Korn T, Weiss S, Förster R, Prinz I.

Arthritis Rheumatol. 2016 Oct;68(10):2476-86. doi: 10.1002/art.39732.

37.

IL-17 is not essential for inflammation and chronic pelvic pain development in an experimental model of chronic prostatitis/chronic pelvic pain syndrome.

Motrich RD, Breser ML, Sánchez LR, Godoy GJ, Prinz I, Rivero VE.

Pain. 2016 Mar;157(3):585-97. doi: 10.1097/j.pain.0000000000000405.

PMID:
26882345
38.

Brief Report: Arthritis in KRN T Cell Receptor-Transgenic Mice Does Not Require Interleukin-17 or Th17 Cells.

Auger JL, Cowan HM, Engelson BJ, Kashem SW, Prinz I, Binstadt BA.

Arthritis Rheumatol. 2016 Aug;68(8):1849-55. doi: 10.1002/art.39646.

39.

Corrigendum: Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes Are More Innate Than Others.

Vermijlen D, Prinz I.

Front Immunol. 2015 Dec 14;6:624. doi: 10.3389/fimmu.2015.00624. eCollection 2015.

40.

MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development.

Sandrock I, Ziętara N, Łyszkiewicz M, Oberdörfer L, Witzlau K, Krueger A, Prinz I.

PLoS One. 2015 Dec 16;10(12):e0145010. doi: 10.1371/journal.pone.0145010. eCollection 2015.

41.

Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients.

Klemann C, Schröder A, Dreier A, Möhn N, Dippel S, Winterberg T, Wilde A, Yu Y, Thorenz A, Gueler F, Jörns A, Tolosa E, Leonhardt J, Haas JD, Prinz I, Vieten G, Petersen C, Kuebler JF.

Gastroenterology. 2016 Jan;150(1):229-241.e5. doi: 10.1053/j.gastro.2015.09.008. Epub 2015 Sep 25.

PMID:
26404950
42.

γδ T cells come to stay: Innate skin memory in the Aldara model.

Prinz I, Sandrock I.

Eur J Immunol. 2015 Nov;45(11):2994-7. doi: 10.1002/eji.201546033. Epub 2015 Oct 12.

43.

Multicongenic fate mapping quantification of dynamics of thymus colonization.

Ziętara N, Łyszkiewicz M, Puchałka J, Witzlau K, Reinhardt A, Förster R, Pabst O, Prinz I, Krueger A.

J Exp Med. 2015 Sep 21;212(10):1589-601. doi: 10.1084/jem.20142143. Epub 2015 Sep 7.

44.

Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.

Yang BH, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, Föhse L, Prinz I, Pezoldt J, Suerbaum S, Sparwasser T, Hamann A, Floess S, Huehn J, Lochner M.

Mucosal Immunol. 2016 Mar;9(2):444-57. doi: 10.1038/mi.2015.74. Epub 2015 Aug 26.

PMID:
26307665
45.

A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6⁺CD27⁻ subset.

Kashani E, Föhse L, Raha S, Sandrock I, Oberdörfer L, Koenecke C, Suerbaum S, Weiss S, Prinz I.

Nat Commun. 2015 Mar 13;6:6477. doi: 10.1038/ncomms7477.

PMID:
25765849
46.

Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis.

Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse AW, Herkel J, Schramm C.

J Immunol. 2015 Mar 15;194(6):2522-30. doi: 10.4049/jimmunol.1400076. Epub 2015 Feb 11.

47.

Limited niche availability suppresses murine intrathymic dendritic-cell development from noncommitted progenitors.

Łyszkiewicz M, Ziętara N, Föhse L, Puchałka J, Diestelhorst J, Witzlau K, Prinz I, Schambach A, Krueger A.

Blood. 2015 Jan 15;125(3):457-64. doi: 10.1182/blood-2014-07-592667. Epub 2014 Nov 19.

PMID:
25411428
48.

Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes are More Innate than Others.

Vermijlen D, Prinz I.

Front Immunol. 2014 Oct 10;5:486. doi: 10.3389/fimmu.2014.00486. eCollection 2014. Review. Erratum in: Front Immunol. 2015;6:624.

49.

γδ T cell subsets play opposing roles in regulating experimental autoimmune encephalomyelitis.

Blink SE, Caldis MW, Goings GE, Harp CT, Malissen B, Prinz I, Xu D, Miller SD.

Cell Immunol. 2014 Jul;290(1):39-51. doi: 10.1016/j.cellimm.2014.04.013. Epub 2014 May 10.

50.

IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs.

Fleige H, Ravens S, Moschovakis GL, Bölter J, Willenzon S, Sutter G, Häussler S, Kalinke U, Prinz I, Förster R.

J Exp Med. 2014 Apr 7;211(4):643-51. doi: 10.1084/jem.20131737. Epub 2014 Mar 24.

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