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Items: 9

1.

Imaging of HIV-1 envelope-induced virological synapse and signaling on synthetic lipid bilayers.

Prins KC, Vasiliver-Shamis G, Cammer M, Depoil D, Dustin ML, Hioe CE.

J Vis Exp. 2012 Mar 8;(61). pii: 3757. doi: 10.3791/3757.

2.

HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA).

Hioe CE, Tuen M, Vasiliver-Shamis G, Alvarez Y, Prins KC, Banerjee S, Nádas A, Cho MW, Dustin ML, Kachlany SC.

PLoS One. 2011;6(8):e23202. doi: 10.1371/journal.pone.0023202. Epub 2011 Aug 5.

3.

Ebolavirus VP35 is a multifunctional virulence factor.

Leung DW, Prins KC, Basler CF, Amarasinghe GK.

Virulence. 2010 Nov-Dec;1(6):526-31. Epub 2010 Nov 1.

4.

Basic residues within the ebolavirus VP35 protein are required for its viral polymerase cofactor function.

Prins KC, Binning JM, Shabman RS, Leung DW, Amarasinghe GK, Basler CF.

J Virol. 2010 Oct;84(20):10581-91. doi: 10.1128/JVI.00925-10. Epub 2010 Aug 4.

5.

Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins.

Leung DW, Borek D, Farahbakhsh M, Ramanan P, Nix JC, Wang T, Prins KC, Otwinowski Z, Honzatko RB, Helgeson LA, Basler CF, Amarasinghe GK.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jun 1;66(Pt 6):689-92. doi: 10.1107/S1744309110013266. Epub 2010 May 27.

6.

Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain.

Leung DW, Shabman RS, Farahbakhsh M, Prins KC, Borek DM, Wang T, Mühlberger E, Basler CF, Amarasinghe GK.

J Mol Biol. 2010 Jun 11;399(3):347-57. doi: 10.1016/j.jmb.2010.04.022. Epub 2010 Apr 24.

7.

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.

Leung DW, Prins KC, Borek DM, Farahbakhsh M, Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski Z, Honzatko RB, Basler CF, Amarasinghe GK.

Nat Struct Mol Biol. 2010 Feb;17(2):165-72. doi: 10.1038/nsmb.1765. Epub 2010 Jan 17.

8.

Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs.

Prins KC, Delpeut S, Leung DW, Reynard O, Volchkova VA, Reid SP, Ramanan P, Cárdenas WB, Amarasinghe GK, Volchkov VE, Basler CF.

J Virol. 2010 Mar;84(6):3004-15. doi: 10.1128/JVI.02459-09. Epub 2010 Jan 13.

9.

Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1.

Prins KC, Cárdenas WB, Basler CF.

J Virol. 2009 Apr;83(7):3069-77. doi: 10.1128/JVI.01875-08. Epub 2009 Jan 19.

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