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Items: 1 to 50 of 129

1.

Immunization with Low Doses of Recombinant Postfusion or Prefusion Respiratory Syncytial Virus F Primes for Vaccine-Enhanced Disease in the Cotton Rat Model Independently of the Presence of a Th1-Biasing (GLA-SE) or Th2-Biasing (Alum) Adjuvant.

Schneider-Ohrum K, Cayatte C, Bennett AS, Rajani GM, McTamney P, Nacel K, Hostetler L, Cheng L, Ren K, O'Day T, Prince GA, McCarthy MP.

J Virol. 2017 Mar 29;91(8). pii: e02180-16. doi: 10.1128/JVI.02180-16. Print 2017 Apr 15.

2.

New insights for development of a safe and protective RSV vaccine.

Blanco JC, Boukhvalova MS, Shirey KA, Prince GA, Vogel SN.

Hum Vaccin. 2010 Jun;6(6):482-92. Epub 2010 Jun 1. Review.

3.

Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model.

Hamelin ME, Gagnon C, Prince GA, Kiener P, Suzich J, Ulbrandt N, Boivin G.

Antiviral Res. 2010 Oct;88(1):31-7. doi: 10.1016/j.antiviral.2010.07.001. Epub 2010 Jul 7.

PMID:
20619294
4.

Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent.

Shirey KA, Pletneva LM, Puche AC, Keegan AD, Prince GA, Blanco JC, Vogel SN.

Mucosal Immunol. 2010 May;3(3):291-300. doi: 10.1038/mi.2010.6. Epub 2010 Mar 10.

5.

Methods for monitoring dynamics of pulmonary RSV replication by viral culture and by real-time reverse transcription-PCR in vivo: Detection of abortive viral replication.

Boukhvalova MS, Yim KC, Prince GA, Blanco JC.

Curr Protoc Cell Biol. 2010 Mar;Chapter 26:Unit26.6. doi: 10.1002/0471143030.cb2606s46.

6.

Inactivation of respiratory syncytial virus by zinc finger reactive compounds.

Boukhvalova MS, Prince GA, Blanco JC.

Virol J. 2010 Jan 26;7:20. doi: 10.1186/1743-422X-7-20.

7.
8.

Comparison of airway measurements during influenza-induced tachypnea in infant and adult cotton rats.

Trias EL, Hassantoufighi A, Prince GA, Eichelberger MC.

BMC Pulm Med. 2009 Jun 10;9:28. doi: 10.1186/1471-2466-9-28.

9.

Expression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection.

Blanco JC, Pletneva LM, Wieczorek L, Khetawat D, Stantchev TS, Broder CC, Polonis VR, Prince GA.

Virol J. 2009 May 14;6:57. doi: 10.1186/1743-422X-6-57.

10.

The cotton rat model of respiratory viral infections.

Boukhvalova MS, Prince GA, Blanco JC.

Biologicals. 2009 Jun;37(3):152-9. doi: 10.1016/j.biologicals.2009.02.017. Epub 2009 Apr 25.

11.

Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia.

Kukavica-Ibrulj I, Hamelin ME, Prince GA, Gagnon C, Bergeron Y, Bergeron MG, Boivin G.

J Virol. 2009 Feb;83(3):1341-9. doi: 10.1128/JVI.01123-08. Epub 2008 Nov 19.

12.

Antibody contributes to heterosubtypic protection against influenza A-induced tachypnea in cotton rats.

Straight TM, Ottolini MG, Prince GA, Eichelberger MC.

Virol J. 2008 Mar 20;5:44. doi: 10.1186/1743-422X-5-44.

13.
14.

Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus.

Deffrasnes C, Hamelin ME, Prince GA, Boivin G.

Antimicrob Agents Chemother. 2008 Jan;52(1):279-87. Epub 2007 Oct 29.

15.

Immunocompetent syngeneic cotton rat tumor models for the assessment of replication-competent oncolytic adenovirus.

Steel JC, Morrison BJ, Mannan P, Abu-Asab MS, Wildner O, Miles BK, Yim KC, Ramanan V, Prince GA, Morris JC.

Virology. 2007 Dec 5;369(1):131-42. Epub 2007 Aug 28.

16.

Co-infection of the cotton rat (Sigmodon hispidus) with Staphylococcus aureus and influenza A virus results in synergistic disease.

Braun LE, Sutter DE, Eichelberger MC, Pletneva L, Kokai-Kun JF, Blanco JC, Prince GA, Ottolini MG.

Microb Pathog. 2007 Nov-Dec;43(5-6):208-16. Epub 2007 Aug 3.

PMID:
17689046
17.

Respiratory syncytial virus infects and abortively replicates in the lungs in spite of preexisting immunity.

Boukhvalova MS, Prince GA, Blanco JC.

J Virol. 2007 Sep;81(17):9443-50. Epub 2007 Jun 27.

18.

Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.

Yim KC, Cragin RP, Boukhvalova MS, Blanco JC, Hamlin ME, Boivin G, Porter DD, Prince GA.

Vaccine. 2007 Jun 28;25(27):5034-40. Epub 2007 May 15.

19.

Respiratory syncytial virus replication is prolonged by a concomitant allergic response.

Hassantoufighi A, Oglesbee M, Richter BW, Prince GA, Hemming V, Niewiesk S, Eichelberger MC.

Clin Exp Immunol. 2007 May;148(2):218-29. Epub 2007 Mar 5.

20.

Distinct cellular immune responses following primary and secondary influenza virus challenge in cotton rats.

Eichelberger MC, Bauchiero S, Point D, Richter BW, Prince GA, Schuman R.

Cell Immunol. 2006 Oct;243(2):67-74. Epub 2007 Feb 15.

PMID:
17306242
21.

Interferon-inducible Mx gene expression in cotton rats: cloning, characterization, and expression during influenza viral infection.

Pletneva LM, Haller O, Porter DD, Prince GA, Blanco JC.

J Interferon Cytokine Res. 2006 Dec;26(12):914-21.

PMID:
17238834
22.

Age-related differences in pulmonary cytokine response to respiratory syncytial virus infection: modulation by anti-inflammatory and antiviral treatment.

Boukhvalova MS, Yim KC, Kuhn KH, Hemming JP, Prince GA, Porter DD, Blanco JC.

J Infect Dis. 2007 Feb 15;195(4):511-8. Epub 2007 Jan 4.

PMID:
17230410
23.

Evidence of a cross-protective immune response to influenza A in the cotton rat model.

Straight TM, Ottolini MG, Prince GA, Eichelberger MC.

Vaccine. 2006 Sep 11;24(37-39):6264-71. Epub 2006 Jun 13.

PMID:
16860444
24.

Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.

Hamelin ME, Prince GA, Gomez AM, Kinkead R, Boivin G.

J Infect Dis. 2006 Jun 15;193(12):1634-42. Epub 2006 May 11.

PMID:
16703506
25.

The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease.

Boukhvalova MS, Prince GA, Soroush L, Harrigan DC, Vogel SN, Blanco JC.

Vaccine. 2006 Jun 5;24(23):5027-35. Epub 2006 Apr 18.

PMID:
16675071
26.

Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection.

Hamelin ME, Prince GA, Boivin G.

Antimicrob Agents Chemother. 2006 Feb;50(2):774-7.

27.

Prospects of antiviral and anti-inflammatory therapy for respiratory syncytial virus infection.

Blanco JC, Boukhvalova MS, Hemming P, Ottolini MG, Prince GA.

Expert Rev Anti Infect Ther. 2005 Dec;3(6):945-55. Review.

PMID:
16307507
28.

The cotton rat provides a novel model to study genital herpes infection and to evaluate preventive strategies.

Yim KC, Carroll CJ, Tuyama A, Cheshenko N, Carlucci MJ, Porter DD, Prince GA, Herold BC.

J Virol. 2005 Dec;79(23):14632-9.

29.

The cotton rat provides a useful small-animal model for the study of influenza virus pathogenesis.

Ottolini MG, Blanco JC, Eichelberger MC, Porter DD, Pletneva L, Richardson JY, Prince GA.

J Gen Virol. 2005 Oct;86(Pt 10):2823-30.

PMID:
16186238
31.

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats.

Hamelin ME, Yim K, Kuhn KH, Cragin RP, Boukhvalova M, Blanco JC, Prince GA, Boivin G.

J Virol. 2005 Jul;79(14):8894-903.

32.
33.

Respiratory syncytial virus (RSV) infection induces cyclooxygenase 2: a potential target for RSV therapy.

Richardson JY, Ottolini MG, Pletneva L, Boukhvalova M, Zhang S, Vogel SN, Prince GA, Blanco JC.

J Immunol. 2005 Apr 1;174(7):4356-64.

34.

Cotton rat tumor model for the evaluation of oncolytic adenoviruses.

Toth K, Spencer JF, Tollefson AE, Kuppuswamy M, Doronin K, Lichtenstein DL, La Regina MC, Prince GA, Wold WS.

Hum Gene Ther. 2005 Jan;16(1):139-46.

PMID:
15703497
35.

Respiratory syncytial virus and other pneumoviruses: a review of the international symposium--RSV 2003.

Schmidt AC, Johnson TR, Openshaw PJ, Braciale TJ, Falsey AR, Anderson LJ, Wertz GW, Groothuis JR, Prince GA, Melero JA, Graham BS.

Virus Res. 2004 Nov;106(1):1-13. Review.

PMID:
15522442
37.

The cotton rat: an underutilized animal model for human infectious diseases can now be exploited using specific reagents to cytokines, chemokines, and interferons.

Blanco JC, Pletneva L, Boukhvalova M, Richardson JY, Harris KA, Prince GA.

J Interferon Cytokine Res. 2004 Jan;24(1):21-8.

PMID:
14980081
38.
39.

A cotton rat model of human parainfluenza 3 laryngotracheitis: virus growth, pathology, and therapy.

Ottolini MG, Porter DD, Blanco JC, Prince GA.

J Infect Dis. 2002 Dec 15;186(12):1713-7. Epub 2002 Nov 14.

PMID:
12447755
40.

Age-dependent replication of respiratory syncytial virus in the cotton rat.

Curtis SJ, Ottolini MG, Porter DD, Prince GA.

Exp Biol Med (Maywood). 2002 Oct;227(9):799-802.

PMID:
12324660
41.

A role for immune complexes in enhanced respiratory syncytial virus disease.

Polack FP, Teng MN, Collins PL, Prince GA, Exner M, Regele H, Lirman DD, Rabold R, Hoffman SJ, Karp CL, Kleeberger SR, Wills-Karp M, Karron RA.

J Exp Med. 2002 Sep 16;196(6):859-65.

42.

Cytokine and chemokine gene expression after primary and secondary respiratory syncytial virus infection in cotton rats.

Blanco JC, Richardson JY, Darnell ME, Rowzee A, Pletneva L, Porter DD, Prince GA.

J Infect Dis. 2002 Jun 15;185(12):1780-5. Epub 2002 May 31.

PMID:
12085325
43.

Comparison of corticosteroids for treatment of respiratory syncytial virus bronchiolitis and pneumonia in cotton rats.

Ottolini MG, Curtis SJ, Porter DD, Mathews A, Richardson JY, Hemming VG, Prince GA.

Antimicrob Agents Chemother. 2002 Jul;46(7):2299-302.

44.

Insertion of HIV-1 genes into Ad4DeltaE3 vector abrogates increased pathogenesis in cotton rats due to E3 deletion.

Patterson LJ, Prince GA, Richardson E, Alvord WG, Kalyan N, Robert-Guroff M.

Virology. 2002 Jan 5;292(1):107-13.

45.
46.

Palivizumab is highly effective in suppressing respiratory syncytial virus in an immunosuppressed animal model.

Ottolini MG, Curtis SR, Mathews A, Ottolini SR, Prince GA.

Bone Marrow Transplant. 2002 Jan;29(2):117-20.

47.
48.
49.

Monophosphoryl lipid A adjuvant reverses a principal histologic parameter of formalin-inactivated respiratory syncytial virus vaccine-induced disease.

Prince GA, Denamur F, Deschamps M, Garçon N, Prieels JP, Slaoui M, Thiriart C, Porter DD.

Vaccine. 2001 Feb 28;19(15-16):2048-54.

PMID:
11228376
50.

An update on respiratory syncytial virus antiviral agents.

Prince GA.

Expert Opin Investig Drugs. 2001 Feb;10(2):297-308. Review.

PMID:
11178342

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