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Items: 1 to 50 of 85

1.

Successful cancer vaccine therapy for carcinoembryonic antigen (CEA)-expressing colon cancer using genetically modified dendritic cells that express CEA and T helper-type 1 cytokines in CEA transgenic mice.

Ojima T, Iwahashi M, Nakamura M, Matsuda K, Nakamori M, Ueda K, Naka T, Ishida K, Primus FJ, Yamaue H.

Int J Cancer. 2007 Feb 1;120(3):585-93.

2.

Adenovirus fiber shaft contains a trimerization element that supports peptide fusion for targeted gene delivery.

Li J, Lad S, Yang G, Luo Y, Iacobelli-Martinez M, Primus FJ, Reisfeld RA, Li E.

J Virol. 2006 Dec;80(24):12324-31. Epub 2006 Oct 4.

3.

CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice.

Saha A, Baral RN, Chatterjee SK, Mohanty K, Pal S, Foon KA, Primus FJ, Krieg AM, Weiner GJ, Bhattacharya-Chatterjee M.

Cancer Immunol Immunother. 2006 May;55(5):515-27. Epub 2005 Jul 26.

PMID:
16044253
4.

DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the NKG2D receptor.

Zhou H, Luo Y, Lo JF, Kaplan CD, Mizutani M, Mizutani N, Lee JD, Primus FJ, Becker JC, Xiang R, Reisfeld RA.

Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10846-51. Epub 2005 Jul 22.

5.

Rationale for antiangiogenic cancer therapy with vaccination using epitope peptides derived from human vascular endothelial growth factor receptor 2.

Wada S, Tsunoda T, Baba T, Primus FJ, Kuwano H, Shibuya M, Tahara H.

Cancer Res. 2005 Jun 1;65(11):4939-46.

6.

Dendritic cells pulsed with an anti-idiotype antibody mimicking carcinoembryonic antigen (CEA) can reverse immunological tolerance to CEA and induce antitumor immunity in CEA transgenic mice.

Saha A, Chatterjee SK, Foon KA, Primus FJ, Sreedharan S, Mohanty K, Bhattacharya-Chatterjee M.

Cancer Res. 2004 Jul 15;64(14):4995-5003.

7.

A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen-based DNA minigene vaccines.

Zhou H, Luo Y, Mizutani M, Mizutani N, Becker JC, Primus FJ, Xiang R, Reisfeld RA.

J Clin Invest. 2004 Jun;113(12):1792-8.

9.

Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunity.

Saha A, Chatterjee SK, Foon KA, Primus FJ, Bhattacharya-Chatterjee M.

Cancer Res. 2003 Jun 1;63(11):2844-54.

10.

An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice.

Niethammer AG, Primus FJ, Xiang R, Dolman CS, Ruehlmann JM, Ba Y, Gillies SD, Reisfeld RA.

Vaccine. 2001 Nov 12;20(3-4):421-9.

PMID:
11672905
11.

A dual-function DNA vaccine encoding carcinoembryonic antigen and CD40 ligand trimer induces T cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice.

Xiang R, Primus FJ, Ruehlmann JM, Niethammer AG, Silletti S, Lode HN, Dolman CS, Gillies SD, Reisfeld RA.

J Immunol. 2001 Oct 15;167(8):4560-5.

12.

Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice.

Xiang R, Silletti S, Lode HN, Dolman CS, Ruehlmann JM, Niethammer AG, Pertl U, Gillies SD, Primus FJ, Reisfeld RA.

Clin Cancer Res. 2001 Mar;7(3 Suppl):856s-864s.

PMID:
11300483
13.

Targeting and therapy of carcinoembryonic antigen-expressing tumors in transgenic mice with an antibody-interleukin 2 fusion protein.

Xu X, Clarke P, Szalai G, Shively JE, Williams LE, Shyr Y, Shi E, Primus FJ.

Cancer Res. 2000 Aug 15;60(16):4475-84.

14.

Induction of cytotoxic T cells and their antitumor activity in mice transgenic for carcinoembryonic antigen.

Mizobata S, Tompkins K, Simpson JF, Shyr Y, Primus FJ.

Cancer Immunol Immunother. 2000 Aug;49(6):285-95.

PMID:
10946810
15.
16.

Dose escalation trial of indium-111-labeled anti-carcinoembryonic antigen chimeric monoclonal antibody (chimeric T84.66) in presurgical colorectal cancer patients.

Wong JY, Chu DZ, Yamauchi D, Odom-Maryon TL, Williams LE, Liu A, Esteban JM, Wu AM, Primus FJ, Beatty JD, Shively JE, Raubitschek AA.

J Nucl Med. 1998 Dec;39(12):2097-104.

17.

A murine model system for detection of neoplasia of the head and neck using transfectomas and carcinoembryonic antigen transgenic mice.

Szalai G, Williams LE, Clarke PE, Primus FJ.

Eur Arch Otorhinolaryngol. 1998;255(5):271-4. No abstract available.

PMID:
9638472
18.

Mice transgenic for human carcinoembryonic antigen as a model for immunotherapy.

Clarke P, Mann J, Simpson JF, Rickard-Dickson K, Primus FJ.

Cancer Res. 1998 Apr 1;58(7):1469-77.

19.

Clinical evaluation of indium-111-labeled chimeric anti-CEA monoclonal antibody.

Wong JY, Thomas GE, Yamauchi D, Williams LE, Odom-Maryon TL, Liu A, Esteban JM, Neumaier M, Dresse S, Wu AM, Primus FJ, Shively JE, Raubitschek AA.

J Nucl Med. 1997 Dec;38(12):1951-9.

20.

Bispecific antibody mediated targeting of nido-carboranes to human colon carcinoma cells.

Primus FJ, Pak RH, Richard-Dickson KJ, Szalai G, Bolen JL Jr, Kane RR, Hawthorne MF.

Bioconjug Chem. 1996 Sep-Oct;7(5):532-5.

PMID:
8889012
21.

Initial experience evaluating 90yttrium-radiolabeled anti-carcinoembryonic antigen chimeric T84.66 in a phase I radioimmunotherapy trial.

Wong JY, Williams LE, Yamauchi DM, Odom-Maryon T, Esteban JM, Neumaier M, Wu AM, Johnson DK, Primus FJ, Shively JE, et al.

Cancer Res. 1995 Dec 1;55(23 Suppl):5929s-5934s.

22.

Preparation and properties of nido-carborane-specific monoclonal antibodies for potential use in boron neutron capture therapy for cancer.

Pak RH, Primus FJ, Rickard-Dickson KJ, Ng LL, Kane RR, Hawthorne MF.

Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6986-90.

23.
24.

Monoclonal antibody gene transfer. Implications for tumor-specific cell-mediated cytotoxicity.

Primus FJ, Finch MD, Wetzel SA, Masci AM, Schlom J, Kashmiri SV.

Ann N Y Acad Sci. 1994 May 31;716:154-65; discussion 165-6. No abstract available.

PMID:
8024192
25.

Self-reactive antibody expression by human carcinoma cells engineered with monoclonal antibody genes.

Primus FJ, Finch MD, Masci AM, Schlom J, Kashmiri SV.

Cancer Res. 1993 Jul 15;53(14):3355-61.

26.

Transfer of the IL-6 gene into a human colorectal carcinoma cell line and consequent enhancement of tumor antigen expression.

Tsang KY, Kashmiri SV, Qi CF, Nieroda C, Calvo B, De Filippi R, Greiner JW, Primus FJ, Schlom J.

Immunol Lett. 1993 May;36(2):179-85.

PMID:
8102353
27.
28.
29.

Characterization of the colorectal carcinoma-associated antigen defined by monoclonal antibody D612.

Fernsten PD, Primus FJ, Greiner JW, Simpson JF, Schlom J.

Cancer Res. 1991 Feb 1;51(3):926-34.

30.

Generation and characterization of a recombinant/chimeric B72.3 (human gamma 1).

Hutzell P, Kashmiri S, Colcher D, Primus FJ, Hand PH, Roselli M, Finch M, Yarranton G, Bodmer M, Whittle N, et al.

Cancer Res. 1991 Jan 1;51(1):181-9.

31.
32.

Lymphokine-activated killer cell cytotoxicity against human colon carcinomas enhanced by monoclonal antibody D612.

Pendurthi TK, Parker R, Schlom J, Primus FJ.

Int J Cancer. 1990 Dec 15;46(6):1021-8.

PMID:
2123477
33.

Chimeric B72.3 mouse/human (IgG1) antibody directs the lysis of tumor cells by lymphokine-activated killer cells.

Primus FJ, Pendurthi TK, Hutzell P, Kashmiri S, Slavin DC, Callahan R, Schlom J.

Cancer Immunol Immunother. 1990;31(6):349-57.

PMID:
2386980
34.

Serologic mapping and biochemical characterization of the carcinoembryonic antigen epitopes using fourteen distinct monoclonal antibodies.

Kuroki M, Greiner JW, Simpson JF, Primus FJ, Guadagni F, Schlom J.

Int J Cancer. 1989 Aug 15;44(2):208-18.

PMID:
2474516
35.

A monoclonal antibody (D612) with selective reactivity for malignant and normal gastro-intestinal epithelium.

Muraro R, Nuti M, Natali PG, Bigotti A, Simpson JF, Primus FJ, Colcher D, Greiner JW, Schlom J.

Int J Cancer. 1989 Apr 15;43(4):598-607.

PMID:
2649441
36.

Antiidiotype antibodies in cancer patients receiving monoclonal antibody to carcinoembryonic antigen.

Traub UC, DeJager RL, Primus FJ, Losman M, Goldenberg DM.

Cancer Res. 1988 Jul 15;48(14):4002-6.

37.

Site-specific linkage of methotrexate to monoclonal antibodies using an intermediate carrier.

Shih LB, Sharkey RM, Primus FJ, Goldenberg DM.

Int J Cancer. 1988 Jun 15;41(6):832-9.

PMID:
2453476
38.

Temperature affects binding of murine monoclonal IgG antibodies to protein A.

Tu YY, Primus FJ, Goldenberg DM.

J Immunol Methods. 1988 Apr 22;109(1):43-7.

PMID:
3356911
39.
40.
41.

Purification and characterization of carcinoembryonic antigen from GW-39, a xenografted human colonic tumor system.

Tu YY, Primus FJ, Shochat D, Goldenberg DM.

Tumour Biol. 1988;9(4):212-20.

PMID:
3420377
42.

Radioimmunotherapy of the GW-39 human colonic tumor xenograft with 131I-labeled murine monoclonal antibody to carcinoembryonic antigen.

Sharkey RM, Pykett MJ, Siegel JA, Alger EA, Primus FJ, Goldenberg DM.

Cancer Res. 1987 Nov 1;47(21):5672-7.

43.

Representation of epitopes on colon-specific antigen-p defined by monoclonal antibodies.

Nocera MA, Shochat D, Primus FJ, Krupey J, Jespersen DL, Goldenberg DM.

J Natl Cancer Inst. 1987 Nov;79(5):943-8.

PMID:
2446045
44.

[Production of monoclonal anti-Mallory body antibody].

Yoshioka K, Kakumu S, Fuji A, Tahara H, Murase K, Unoura M, Primus FJ, Leevy CM.

Nihon Shokakibyo Gakkai Zasshi. 1987 Jun;84(6):1251-7. Japanese. No abstract available.

PMID:
3312729
45.

Antibody protein dose and radioimmunodetection of GW-39 human colon tumor xenografts.

Sharkey RM, Primus FJ, Goldenberg DM.

Int J Cancer. 1987 May 15;39(5):611-7.

PMID:
3570553
46.
47.

ABH and Lewis blood group expression in colorectal carcinoma.

Schoentag R, Primus FJ, Kuhns W.

Cancer Res. 1987 Mar 15;47(6):1695-700.

48.

A human colon cancer metastasis model for radioimmunodetection.

Sharkey RM, Filion D, Fand I, Primus FJ, Goldenberg DM.

Cancer Res. 1986 Jul;46(7):3677-83.

49.

Quantitative whole-body autoradiography of radiolabeled antibody distribution in a xenografted human cancer model.

Fand I, Sharkey RM, McNally WP, Brill AB, Som P, Yamamoto K, Primus FJ, Goldenberg DM.

Cancer Res. 1986 Jan;46(1):271-7.

50.

Second antibody clearance of radiolabeled antibody in cancer radioimmunodetection.

Sharkey RM, Primus FJ, Goldenberg DM.

Proc Natl Acad Sci U S A. 1984 May;81(9):2843-6.

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