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Items: 1 to 50 of 81

1.

Characterization of mouse sperm TMEM190, a small transmembrane protein with the trefoil domain: evidence for co-localization with IZUMO1 and complex formation with other sperm proteins.

Nishimura H, Gupta S, Myles DG, Primakoff P.

Reproduction. 2011 Apr;141(4):437-51. doi: 10.1530/REP-10-0391. Epub 2011 Jan 27.

PMID:
21273369
2.

Testase 1 (ADAM 24) a sperm surface metalloprotease is required for normal fertility in mice.

Zhu GZ, Gupta S, Myles DG, Primakoff P.

Mol Reprod Dev. 2009 Nov;76(11):1106-14. doi: 10.1002/mrd.21076.

PMID:
19670298
3.

Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm.

Ellerman DA, Pei J, Gupta S, Snell WJ, Myles D, Primakoff P.

Mol Reprod Dev. 2009 Dec;76(12):1188-99. doi: 10.1002/mrd.21092.

4.

Can the presence of wild-type oocytes during insemination rescue the fusion defect of CD9 null oocytes?

Gupta S, Primakoff P, Myles DG.

Mol Reprod Dev. 2009 Jul;76(7):602. doi: 10.1002/mrd.21040. No abstract available.

PMID:
19363789
5.

Loss of surface EWI-2 on CD9 null oocytes.

He ZY, Gupta S, Myles D, Primakoff P.

Mol Reprod Dev. 2009 Jul;76(7):629-36. doi: 10.1002/mrd.20991.

PMID:
19107828
6.

Identification of an ADAM2-ADAM3 complex on the surface of mouse testicular germ cells and cauda epididymal sperm.

Nishimura H, Myles DG, Primakoff P.

J Biol Chem. 2007 Jun 15;282(24):17900-7. Epub 2007 Apr 17.

7.

Cell-cell membrane fusion during mammalian fertilization.

Primakoff P, Myles DG.

FEBS Lett. 2007 May 22;581(11):2174-80. Epub 2007 Feb 20. Review.

8.

Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution.

Runge KE, Evans JE, He ZY, Gupta S, McDonald KL, Stahlberg H, Primakoff P, Myles DG.

Dev Biol. 2007 Apr 1;304(1):317-25. Epub 2006 Dec 23.

9.

Proteomic analysis of sperm regions that mediate sperm-egg interactions.

Stein KK, Go JC, Lane WS, Primakoff P, Myles DG.

Proteomics. 2006 Jun;6(12):3533-43.

PMID:
16758446
10.
11.

Defects in secretory pathway trafficking during sperm development in Adam2 knockout mice.

Stein KK, Go JC, Primakoff P, Myles DG.

Biol Reprod. 2005 Nov;73(5):1032-8. Epub 2005 Jul 13.

PMID:
16014818
12.

Sperm-egg fusion: events at the plasma membrane.

Stein KK, Primakoff P, Myles D.

J Cell Sci. 2004 Dec 15;117(Pt 26):6269-74.

13.

Direct binding of the ligand PSG17 to CD9 requires a CD9 site essential for sperm-egg fusion.

Ellerman DA, Ha C, Primakoff P, Myles DG, Dveksler GS.

Mol Biol Cell. 2003 Dec;14(12):5098-103. Epub 2003 Oct 3.

14.

Infertility in female mice with an oocyte-specific knockout of GPI-anchored proteins.

Alfieri JA, Martin AD, Takeda J, Kondoh G, Myles DG, Primakoff P.

J Cell Sci. 2003 Jun 1;116(Pt 11):2149-55. Epub 2003 Apr 8.

15.

None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion.

He ZY, Brakebusch C, Fässler R, Kreidberg JA, Primakoff P, Myles DG.

Dev Biol. 2003 Feb 15;254(2):226-37.

16.

Penetration, adhesion, and fusion in mammalian sperm-egg interaction.

Primakoff P, Myles DG.

Science. 2002 Jun 21;296(5576):2183-5. Review.

PMID:
12077404
17.
18.

Residues SFQ (173-175) in the large extracellular loop of CD9 are required for gamete fusion.

Zhu GZ, Miller BJ, Boucheix C, Rubinstein E, Liu CC, Hynes RO, Myles DG, Primakoff P.

Development. 2002 Apr;129(8):1995-2002.

19.

Immunological response of female macaques to the PH-20 sperm protein following injection of recombinant proteins or synthesized peptides.

Deng X, Meyers SA, Tollner TL, Yudin AI, Primakoff PD, He DN, Overstreet JW.

J Reprod Immunol. 2002 Mar;54(1-2):93-115.

PMID:
11839398
20.

Analysis of loss of adhesive function in sperm lacking cyritestin or fertilin beta.

Nishimura H, Cho C, Branciforte DR, Myles DG, Primakoff P.

Dev Biol. 2001 May 1;233(1):204-13.

22.

A role for a TIMP-3-sensitive, Zn(2+)-dependent metalloprotease in mammalian gamete membrane fusion.

Correa LM, Cho C, Myles DG, Primakoff P.

Dev Biol. 2000 Sep 1;225(1):124-34.

23.

Normal fertilization occurs with eggs lacking the integrin alpha6beta1 and is CD9-dependent.

Miller BJ, Georges-Labouesse E, Primakoff P, Myles DG.

J Cell Biol. 2000 Jun 12;149(6):1289-96.

25.

The ADAM gene family: surface proteins with adhesion and protease activity.

Primakoff P, Myles DG.

Trends Genet. 2000 Feb;16(2):83-7. Review.

PMID:
10652535
26.
27.

Identification of four novel ADAMs with potential roles in spermatogenesis and fertilization.

Zhu GZ, Lin Y, Myles DG, Primakoff P.

Gene. 1999 Jul 8;234(2):227-37.

PMID:
10395895
28.

Fertilization defects in sperm from mice lacking fertilin beta.

Cho C, Bunch DO, Faure JE, Goulding EH, Eddy EM, Primakoff P, Myles DG.

Science. 1998 Sep 18;281(5384):1857-9.

29.

Inhibition of monkey sperm hyaluronidase activity and heterologous cumulus penetration by flavonoids.

Li MW, Yudin AI, VandeVoort CA, Sabeur K, Primakoff P, Overstreet JW.

Biol Reprod. 1997 Jun;56(6):1383-9.

PMID:
9166689
30.

Reversible contraceptive effect of PH-20 immunization in male guinea pigs.

Primakoff P, Woolman-Gamer L, Tung KS, Myles DG.

Biol Reprod. 1997 May;56(5):1142-6.

PMID:
9160712
31.

Mechanism of infertility in male guinea pigs immunized with sperm PH-20.

Tung KS, Primakoff P, Woolman-Gamer L, Myles DG.

Biol Reprod. 1997 May;56(5):1133-41.

PMID:
9160711
33.

The PH-20 protein in human spermatozoa.

Sabeur K, Cherr GN, Yudin AI, Primakoff P, Li MW, Overstreet JW.

J Androl. 1997 Mar-Apr;18(2):151-8.

34.

Hyaluronidase activity of macaque sperm assessed by an in vitro cumulus penetration assay.

Meyers SA, Yudin AI, Cherr GN, VandeVoort CA, Myles DG, Primakoff P, Overstreet JW.

Mol Reprod Dev. 1997 Mar;46(3):392-400.

PMID:
9041143
36.

The mouse Spam1 maps to proximal chromosome 6 and is a candidate for the sperm dysfunction in Rb(6.16)24Lub and Rb(6.15)1Ald heterozygotes.

Deng X, Moran J, Copeland NG, Gilbert DJ, Jenkins NA, Primakoff P, Martin-DeLeon PA.

Mamm Genome. 1997 Feb;8(2):94-7.

PMID:
9060406
37.
40.

Structural relationship of sperm soluble hyaluronidase to the sperm membrane protein PH-20.

Hunnicutt GR, Mahan K, Lathrop WF, Ramarao CS, Myles DG, Primakoff P.

Biol Reprod. 1996 Jun;54(6):1343-9.

PMID:
8724363
41.

The PH-20 protein in cynomolgus macaque spermatozoa: identification of two different forms exhibiting hyaluronidase activity.

Cherr GN, Meyers SA, Yudin AI, VandeVoort CA, Myles DG, Primakoff P, Overstreet JW.

Dev Biol. 1996 Apr 10;175(1):142-53.

42.
43.
44.

Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor.

Almeida EA, Huovila AP, Sutherland AE, Stephens LE, Calarco PG, Shaw LM, Mercurio AM, Sonnenberg A, Primakoff P, Myles DG, White JM.

Cell. 1995 Jun 30;81(7):1095-104.

45.

ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain.

Wolfsberg TG, Straight PD, Gerena RL, Huovila AP, Primakoff P, Myles DG, White JM.

Dev Biol. 1995 May;169(1):378-83.

46.

Location of the PH-20 protein on acrosome-intact and acrosome-reacted spermatozoa of cynomolgus macaques.

Overstreet JW, Lin Y, Yudin AI, Meyers SA, Primakoff P, Myles DG, Katz DF, Vandevoort CA.

Biol Reprod. 1995 Jan;52(1):105-14.

PMID:
7711169
47.
48.

Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion.

Myles DG, Kimmel LH, Blobel CP, White JM, Primakoff P.

Proc Natl Acad Sci U S A. 1994 May 10;91(10):4195-8.

49.

Sperm proteins being studied for use in a contraceptive vaccine.

Primakoff P.

Am J Reprod Immunol. 1994 May;31(4):208-10. Review. No abstract available.

PMID:
8060505
50.

The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications.

Wolfsberg TG, Bazan JF, Blobel CP, Myles DG, Primakoff P, White JM.

Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10783-7.

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