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Items: 25


Control of protein function through oxidation and reduction of persulfidated states.

Dóka É, Ida T, Dagnell M, Abiko Y, Luong NC, Balog N, Takata T, Espinosa B, Nishimura A, Cheng Q, Funato Y, Miki H, Fukuto JM, Prigge JR, Schmidt EE, Arnér ESJ, Kumagai Y, Akaike T, Nagy P.

Sci Adv. 2020 Jan 1;6(1):eaax8358. doi: 10.1126/sciadv.aax8358. eCollection 2020 Jan.


TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy.

McLoughlin MR, Orlicky DJ, Prigge JR, Krishna P, Talago EA, Cavigli IR, Eriksson S, Miller CG, Kundert JA, Sayin VI, Sabol RA, Heinemann J, Brandenberger LO, Iverson SV, Bothner B, Papagiannakopoulos T, Shearn CT, Arnér ESJ, Schmidt EE.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11408-11417. doi: 10.1073/pnas.1903244116. Epub 2019 May 16.


Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, Thomas CJ, Goparaju C, Davies A, Dolgalev I, Heguy A, Allaj V, Poirier JT, Moreira AL, Rudin CM, Pass HI, Vander Heiden MG, Jacks T, Papagiannakopoulos T.

Nat Med. 2017 Nov;23(11):1362-1368. doi: 10.1038/nm.4407. Epub 2017 Oct 2.


Nrf2 regulates cellular behaviors and Notch signaling in oral squamous cell carcinoma cells.

Fan H, Paiboonrungruan C, Zhang X, Prigge JR, Schmidt EE, Sun Z, Chen X.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):833-839. doi: 10.1016/j.bbrc.2017.08.049. Epub 2017 Aug 15.


Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase.

Prigge JR, Coppo L, Martin SS, Ogata F, Miller CG, Bruschwein MD, Orlicky DJ, Shearn CT, Kundert JA, Lytchier J, Herr AE, Mattsson Å, Taylor MP, Gustafsson TN, Arnér ESJ, Holmgren A, Schmidt EE.

Cell Rep. 2017 Jun 27;19(13):2771-2781. doi: 10.1016/j.celrep.2017.06.019.


Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety.

Lan A, Li W, Liu Y, Xiong Z, Zhang X, Zhou S, Palko O, Chen H, Kapita M, Prigge JR, Schmidt EE, Chen X, Sun Z, Chen XL.

Oncotarget. 2016 Aug 16;7(33):53502-53514. doi: 10.18632/oncotarget.10609.


Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection.

Shepardson KM, Larson K, Morton RV, Prigge JR, Schmidt EE, Huber VC, Rynda-Apple A.

mBio. 2016 May 3;7(3). pii: e00506-16. doi: 10.1128/mBio.00506-16.


A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.

Dóka É, Pader I, Bíró A, Johansson K, Cheng Q, Ballagó K, Prigge JR, Pastor-Flores D, Dick TP, Schmidt EE, Arnér ES, Nagy P.

Sci Adv. 2016 Jan 22;2(1):e1500968. doi: 10.1126/sciadv.1500968. eCollection 2016 Jan.


Type I IFNs Act upon Hematopoietic Progenitors To Protect and Maintain Hematopoiesis during Pneumocystis Lung Infection in Mice.

Prigge JR, Hoyt TR, Dobrinen E, Capecchi MR, Schmidt EE, Meissner N.

J Immunol. 2015 Dec 1;195(11):5347-57. doi: 10.4049/jimmunol.1501553. Epub 2015 Oct 30.


Non-Invasive Quantification of Cartilage Using a Novel In Vivo Bioluminescent Reporter Mouse.

Mailhiot SE, Zignego DL, Prigge JR, Wardwell ER, Schmidt EE, June RK.

PLoS One. 2015 Jul 7;10(7):e0130564. doi: 10.1371/journal.pone.0130564. eCollection 2015.


Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver.

Eriksson S, Prigge JR, Talago EA, Arnér ES, Schmidt EE.

Nat Commun. 2015 Mar 20;6:6479. doi: 10.1038/ncomms7479.


Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo.

Chen H, Fu J, Chen H, Hu Y, Soroka DN, Prigge JR, Schmidt EE, Yan F, Major MB, Chen X, Sang S.

Chem Res Toxicol. 2014 Sep 15;27(9):1575-85. doi: 10.1021/tx500211x. Epub 2014 Sep 2.


Hydrodynamic delivery of Cre protein to lineage-mark or time-stamp mouse hepatocytes in situ.

Sonsteng KM, Prigge JR, Talago EA, June RK, Schmidt EE.

PLoS One. 2014 Mar 13;9(3):e91219. doi: 10.1371/journal.pone.0091219. eCollection 2014.


Nuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei.

Prigge JR, Wiley JA, Talago EA, Young EM, Johns LL, Kundert JA, Sonsteng KM, Halford WP, Capecchi MR, Schmidt EE.

Mamm Genome. 2013 Sep 11. [Epub ahead of print]


A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification.

Iverson SV, Eriksson S, Xu J, Prigge JR, Talago EA, Meade TA, Meade ES, Capecchi MR, Arnér ES, Schmidt EE.

Free Radic Biol Med. 2013 Oct;63:369-80. doi: 10.1016/j.freeradbiomed.2013.05.028. Epub 2013 Jun 3.


Thioredoxin reductase inhibition elicits Nrf2-mediated responses in Clara cells: implications for oxidant-induced lung injury.

Locy ML, Rogers LK, Prigge JR, Schmidt EE, Arnér ES, Tipple TE.

Antioxid Redox Signal. 2012 Nov 15;17(10):1407-16. doi: 10.1089/ars.2011.4377. Epub 2012 Jun 25.


Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1.

Prigge JR, Eriksson S, Iverson SV, Meade TA, Capecchi MR, Arnér ES, Schmidt EE.

Free Radic Biol Med. 2012 Feb 15;52(4):803-10. doi: 10.1016/j.freeradbiomed.2011.11.025. Epub 2011 Dec 8.


Cre activity in fetal albCre mouse hepatocytes: Utility for developmental studies.

Weisend CM, Kundert JA, Suvorova ES, Prigge JR, Schmidt EE.

Genesis. 2009 Dec;47(12):789-92. doi: 10.1002/dvg.20568.


Interactome for auxiliary splicing factor U2AF(65) suggests diverse roles.

Prigge JR, Iverson SV, Siders AM, Schmidt EE.

Biochim Biophys Acta. 2009 Jun-Aug;1789(6-8):487-92. doi: 10.1016/j.bbagrm.2009.06.002. Epub 2009 Jun 18.


Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome.

Bondareva AA, Capecchi MR, Iverson SV, Li Y, Lopez NI, Lucas O, Merrill GF, Prigge JR, Siders AM, Wakamiya M, Wallin SL, Schmidt EE.

Free Radic Biol Med. 2007 Sep 15;43(6):911-23. Epub 2007 May 31.


Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP.

Prigge JR, Schmidt EE.

J Biol Chem. 2006 May 5;281(18):12260-9. Epub 2006 Mar 6.


Molecular analysis of the bison phagocyte NADPH oxidase: cloning and sequencing of five NADPH oxidase cDNAs.

Gauss KA, Bunger PL, Siemsen DW, Young CJ, Nelson-Overton L, Prigge JR, Swain SD, Quinn MT.

Comp Biochem Physiol B Biochem Mol Biol. 2002 Sep;133(1):1-12.


Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids.

Schmidt EE, Taylor DS, Prigge JR, Barnett S, Capecchi MR.

Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13702-7.


Phage display epitope mapping of human neutrophil flavocytochrome b558. Identification of two juxtaposed extracellular domains.

Burritt JB, DeLeo FR, McDonald CL, Prigge JR, Dinauer MC, Nakamura M, Nauseef WM, Jesaitis AJ.

J Biol Chem. 2001 Jan 19;276(3):2053-61. Epub 2000 Oct 10.

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