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Items: 33


Human Tolerogenic Dendritic Cells Regulate Immune Responses through Lactate Synthesis.

Marin E, Bouchet-Delbos L, Renoult O, Louvet C, Nerriere-Daguin V, Managh AJ, Even A, Giraud M, Vu Manh TP, Aguesse A, Bériou G, Chiffoleau E, Alliot-Licht B, Prieur X, Croyal M, Hutchinson JA, Obermajer N, Geissler EK, Vanhove B, Blancho G, Dalod M, Josien R, Pecqueur C, Cuturi MC, Moreau A.

Cell Metab. 2019 Dec 3;30(6):1075-1090.e8. doi: 10.1016/j.cmet.2019.11.011.


Chronic O-GlcNAcylation and Diabetic Cardiomyopathy: The Bitterness of Glucose.

Ducheix S, Magré J, Cariou B, Prieur X.

Front Endocrinol (Lausanne). 2018 Oct 29;9:642. doi: 10.3389/fendo.2018.00642. eCollection 2018. Review.


In vivo evidence for transintestinal cholesterol efflux in patients with complete common bile duct obstruction.

Moreau F, Blanchard C, Perret C, Flet L, Douane F, Frampas E, Mirallie E, Croyal M, Aguesse A, Krempf M, Prieur X, Pichelin M, Cariou B, Le May C.

J Clin Lipidol. 2019 Jan - Feb;13(1):213-217.e1. doi: 10.1016/j.jacl.2018.09.010. Epub 2018 Sep 21.


Diabetes-related cardiomyopathy: The sweet story of glucose overload from epidemiology to cellular pathways.

Joubert M, Manrique A, Cariou B, Prieur X.

Diabetes Metab. 2019 Jun;45(3):238-247. doi: 10.1016/j.diabet.2018.07.003. Epub 2018 Jul 23. Review.


[At the heart of diabetic cardiomyopathy: Bscl2 knockout mice to investigate glucotoxicity].

Lugat A, Joubert M, Cariou B, Prieur X.

Med Sci (Paris). 2018 Jun-Jul;34(6-7):563-570. doi: 10.1051/medsci/20183406016. Epub 2018 Jul 31. Review. French.


P465L-PPARγ mutation confers partial resistance to the hypolipidaemic action of fibrates.

Rodriguez-Cuenca S, Carobbio S, Barceló-Coblijn G, Prieur X, Relat J, Amat R, Campbell M, Dias AR, Bahri M, Gray SL, Vidal-Puig A.

Diabetes Obes Metab. 2018 Oct;20(10):2339-2350. doi: 10.1111/dom.13370. Epub 2018 Jun 27.


Roux-en-Y gastric bypass reduces plasma cholesterol in diet-induced obese mice by affecting trans-intestinal cholesterol excretion and intestinal cholesterol absorption.

Blanchard C, Moreau F, Ayer A, Toque L, Garçon D, Arnaud L, Borel F, Aguesse A, Croyal M, Krempf M, Prieur X, Neunlist M, Cariou B, Le May C.

Int J Obes (Lond). 2018 Mar;42(3):552-560. doi: 10.1038/ijo.2017.232. Epub 2017 Sep 28.


Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis.

Carbone ML, Chadeuf G, Heurtebise-Chrétien S, Prieur X, Quillard T, Goueffic Y, Vaillant N, Rio M, Castan L, Durand M, Baron-Menguy C, Aureille J, Desfrançois J, Tesse A, Torres RM, Loirand G.

J Clin Invest. 2017 Dec 1;127(12):4516-4526. doi: 10.1172/JCI92702. Epub 2017 Nov 13.


Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice.

Ayer A, Borel F, Moreau F, Prieur X, Neunlist M, Cariou B, Blanchard C, Le May C.

J Vis Exp. 2017 Mar 20;(121). doi: 10.3791/54905.


The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model.

Joubert M, Jagu B, Montaigne D, Marechal X, Tesse A, Ayer A, Dollet L, Le May C, Toumaniantz G, Manrique A, Charpentier F, Staels B, Magré J, Cariou B, Prieur X.

Diabetes. 2017 Apr;66(4):1030-1040. doi: 10.2337/db16-0733. Epub 2017 Jan 4.


Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode.

Dollet L, Magré J, Joubert M, Le May C, Ayer A, Arnaud L, Pecqueur C, Blouin V, Cariou B, Prieur X.

Sci Rep. 2016 Oct 17;6:35487. doi: 10.1038/srep35487.


One-year metreleptin therapy decreases PCSK9 serum levels in diabetic patients with monogenic lipodystrophy syndromes.

Vatier C, Arnaud L, Prieur X, Guyomarch B, Le May C, Bigot E, Pichelin M, Daguenel A, Vantyghem MC, Gautier JF, Vigouroux C, Cariou B.

Diabetes Metab. 2017 Jun;43(3):275-279. doi: 10.1016/j.diabet.2016.08.004. Epub 2016 Sep 28. No abstract available.


FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency.

Dollet L, Levrel C, Coskun T, Le Lay S, Le May C, Ayer A, Venara Q, Adams AC, Gimeno RE, Magré J, Cariou B, Prieur X.

Diabetes. 2016 Nov;65(11):3410-3417. Epub 2016 Aug 23.


Indicators of iron status are correlated with adiponectin expression in adipose tissue of patients with morbid obesity.

Pihan-Le Bars F, Bonnet F, Loréal O, Le Loupp AG, Ropert M, Letessier E, Prieur X, Bach K, Deugnier Y, Fromenty B, Cariou B.

Diabetes Metab. 2016 Apr;42(2):105-11. doi: 10.1016/j.diabet.2015.10.007. Epub 2015 Dec 8.


PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.

Berger JM, Vaillant N, Le May C, Calderon C, Brégeon J, Prieur X, Hadchouel J, Loirand G, Cariou B.

Atherosclerosis. 2015 Mar;239(1):252-9. doi: 10.1016/j.atherosclerosis.2015.01.012. Epub 2015 Jan 19.


Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation.

Patel MN, Bernard WG, Milev NB, Cawthorn WP, Figg N, Hart D, Prieur X, Virtue S, Hegyi K, Bonnafous S, Bailly-Maitre B, Chu Y, Griffin JL, Mallat Z, Considine RV, Tran A, Gual P, Takeuchi O, Akira S, Vidal-Puig A, Bennett MR, Sethi JK.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):506-11. doi: 10.1073/pnas.1414536112. Epub 2014 Dec 24.


Congenital lipodystrophies and dyslipidemias.

Prieur X, Le May C, Magré J, Cariou B.

Curr Atheroscler Rep. 2014 Sep;16(9):437. doi: 10.1007/s11883-014-0437-x. Review.


Function of seipin: new insights from Bscl2/seipin knockout mouse models.

Dollet L, Magré J, Cariou B, Prieur X.

Biochimie. 2014 Jan;96:166-72. doi: 10.1016/j.biochi.2013.06.022. Epub 2013 Jul 2. Review.


Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice.

Prieur X, Dollet L, Takahashi M, Nemani M, Pillot B, Le May C, Mounier C, Takigawa-Imamura H, Zelenika D, Matsuda F, Fève B, Capeau J, Lathrop M, Costet P, Cariou B, Magré J.

Diabetologia. 2013 Aug;56(8):1813-25. doi: 10.1007/s00125-013-2926-9. Epub 2013 May 17.


Transintestinal cholesterol excretion is an active metabolic process modulated by PCSK9 and statin involving ABCB1.

Le May C, Berger JM, Lespine A, Pillot B, Prieur X, Letessier E, Hussain MM, Collet X, Cariou B, Costet P.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1484-93. doi: 10.1161/ATVBAHA.112.300263. Epub 2013 Apr 4.


Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response.

Camacho A, Rodriguez-Cuenca S, Blount M, Prieur X, Barbarroja N, Fuller M, Hardingham GE, Vidal-Puig A.

Exp Neurol. 2012 Oct;237(2):396-406. doi: 10.1016/j.expneurol.2012.06.031. Epub 2012 Jul 6. Erratum in: Exp Neurol. 2013 Jan;239:101.


n-3 PUFA prevent metabolic disturbances associated with obesity and improve endothelial function in golden Syrian hamsters fed with a high-fat diet.

Kasbi Chadli F, Andre A, Prieur X, Loirand G, Meynier A, Krempf M, Nguyen P, Ouguerram K.

Br J Nutr. 2012 May;107(9):1305-15. doi: 10.1017/S0007114511004387. Epub 2011 Sep 16.


Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice.

Prieur X, Mok CY, Velagapudi VR, Núñez V, Fuentes L, Montaner D, Ishikawa K, Camacho A, Barbarroja N, O'Rahilly S, Sethi JK, Dopazo J, Orešič M, Ricote M, Vidal-Puig A.

Diabetes. 2011 Mar;60(3):797-809. doi: 10.2337/db10-0705. Epub 2011 Jan 24.


Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome.

Prieur X, Roszer T, Ricote M.

Biochim Biophys Acta. 2010 Mar;1801(3):327-37. doi: 10.1016/j.bbalip.2009.09.017. Epub 2009 Sep 29. Review.


Differential regulation of the human versus the mouse apolipoprotein AV gene by PPARalpha. Implications for the study of pharmaceutical modifiers of hypertriglyceridemia in mice.

Prieur X, Lesnik P, Moreau M, Rodríguez JC, Doucet C, Chapman MJ, Huby T.

Biochim Biophys Acta. 2009 Aug;1791(8):764-71. doi: 10.1016/j.bbalip.2009.03.015. Epub 2009 Apr 9.


Functional characterization of naturally occurring pathogenic mutations in the human leptin receptor.

Kimber W, Peelman F, Prieur X, Wangensteen T, O'Rahilly S, Tavernier J, Farooqi IS.

Endocrinology. 2008 Dec;149(12):6043-52. doi: 10.1210/en.2008-0544. Epub 2008 Aug 14.


Leptin regulates peripheral lipid metabolism primarily through central effects on food intake.

Prieur X, Tung YC, Griffin JL, Farooqi IS, O'Rahilly S, Coll AP.

Endocrinology. 2008 Nov;149(11):5432-9. doi: 10.1210/en.2008-0498. Epub 2008 Jul 17.


The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.

Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, Ma M, Jovanovic Z, Farooqi IS, Sedgwick B, Barroso I, Lindahl T, Ponting CP, Ashcroft FM, O'Rahilly S, Schofield CJ.

Science. 2007 Nov 30;318(5855):1469-72. Epub 2007 Nov 8.


The lipoprotein lipase inhibitor ANGPTL3 is negatively regulated by thyroid hormone.

Fugier C, Tousaint JJ, Prieur X, Plateroti M, Samarut J, Delerive P.

J Biol Chem. 2006 Apr 28;281(17):11553-9. Epub 2006 Feb 27.


Thyroid hormone regulates the hypotriglyceridemic gene APOA5.

Prieur X, Huby T, Coste H, Schaap FG, Chapman MJ, Rodríguez JC.

J Biol Chem. 2005 Jul 29;280(30):27533-43. Epub 2005 Jun 7.


Identification of the LIM protein FHL2 as a coactivator of beta-catenin.

Wei Y, Renard CA, Labalette C, Wu Y, Lévy L, Neuveut C, Prieur X, Flajolet M, Prigent S, Buendia MA.

J Biol Chem. 2003 Feb 14;278(7):5188-94. Epub 2002 Dec 3.

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