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Items: 43

1.

Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus.

Reeve SM, Si D, Krucinska J, Yan Y, Viswanathan K, Wang S, Holt GT, Frenkel MS, Ojewole AA, Estrada A, Agabiti SS, Alverson JB, Gibson ND, Priestley ND, Wiemer AJ, Donald BR, Wright DL.

ACS Infect Dis. 2019 Oct 15. doi: 10.1021/acsinfecdis.9b00222. [Epub ahead of print]

PMID:
31565920
2.

Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates.

Lombardo MN, G-Dayanandan N, Keshipeddy S, Zhou W, Si D, Reeve SM, Alverson J, Barney P, Walker L, Hoody J, Priestley ND, Obach RS, Wright DL.

Drug Metab Dispos. 2019 Sep;47(9):995-1003. doi: 10.1124/dmd.119.086504. Epub 2019 Jun 14.

PMID:
31201212
3.

A Controlled Antibiotic Release System for the Development of Single-Application Otitis Externa Therapeutics.

Serban BA, Stipe KT, Alverson JB, Johnston ER, Priestley ND, Serban MA.

Gels. 2017 May 17;3(2). pii: E19. doi: 10.3390/gels3020019.

4.

The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture.

Stierle AA, Stierle DB, Decato D, Priestley ND, Alverson JB, Hoody J, McGrath K, Klepacki D.

J Nat Prod. 2017 Apr 28;80(4):1150-1160. doi: 10.1021/acs.jnatprod.7b00133. Epub 2017 Mar 22.

5.

Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse.

Hoody J, Alverson JB, Keshipeddy S, Barney PA, Walker L, Anderson AC, Wright DL, Priestley ND.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Apr 15;1051:54-59. doi: 10.1016/j.jchromb.2017.02.026. Epub 2017 Mar 6.

6.

Heterodyne mixing of millimetre electromagnetic waves and sub-THz sound in a semiconductor device.

Heywood SL, Glavin BA, Beardsley RP, Akimov AV, Carr MW, Norman J, Norton PC, Prime B, Priestley N, Kent AJ.

Sci Rep. 2016 Aug 1;6:30396. doi: 10.1038/srep30396.

7.

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.

Scocchera E, Reeve SM, Keshipeddy S, Lombardo MN, Hajian B, Sochia AE, Alverson JB, Priestley ND, Anderson AC, Wright DL.

ACS Med Chem Lett. 2016 May 5;7(7):692-6. doi: 10.1021/acsmedchemlett.6b00120. eCollection 2016 Jul 14.

8.

Crystal structures of Klebsiella pneumoniae dihydrofolate reductase bound to propargyl-linked antifolates reveal features for potency and selectivity.

Lamb KM, Lombardo MN, Alverson J, Priestley ND, Wright DL, Anderson AC.

Antimicrob Agents Chemother. 2014 Dec;58(12):7484-91. doi: 10.1128/AAC.03555-14. Epub 2014 Oct 6.

9.

De novo macrolide-glycolipid macrolactone hybrids: Synthesis, structure and antibiotic activity of carbohydrate-fused macrocycles.

Desmond RT, Magpusao AN, Lorenc C, Alverson JB, Priestley N, Peczuh MW.

Beilstein J Org Chem. 2014 Sep 17;10:2215-21. doi: 10.3762/bjoc.10.229. eCollection 2014.

10.

Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata.

G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC.

J Med Chem. 2014 Mar 27;57(6):2643-56. doi: 10.1021/jm401916j. Epub 2014 Mar 6.

11.

The furan route to tropolones: probing the antiproliferative effects of β-thujaplicin analogs.

Oblak EZ, Bolstad ES, Ononye SN, Priestley ND, Hadden MK, Wright DL.

Org Biomol Chem. 2012 Nov 21;10(43):8597-604. doi: 10.1039/c2ob26553b.

PMID:
23032214
12.

Toward new therapeutics for skin and soft tissue infections: propargyl-linked antifolates are potent inhibitors of MRSA and Streptococcus pyogenes.

Viswanathan K, Frey KM, Scocchera EW, Martin BD, Swain Iii PW, Alverson JB, Priestley ND, Anderson AC, Wright DL.

PLoS One. 2012;7(2):e29434. doi: 10.1371/journal.pone.0029434. Epub 2012 Feb 7.

13.

Synthesis of a functionalized oxabicyclo[2.2.1]-heptene-based chemical library.

Luesse SB, Wells G, Miller J, Bolstad E, Bergmeier SC, McMills MC, Priestley ND, Wright DL.

Comb Chem High Throughput Screen. 2012 Jan;15(1):81-9.

PMID:
21774767
14.

Nonactin biosynthesis: unexpected patterns of label incorporation from 4,6-dioxoheptanoate show evidence of a degradation pathway for levulinate through propionate in Streptomyces griseus.

Rong J, Nelson ME, Kusche B, Priestley ND.

J Nat Prod. 2010 Dec 27;73(12):2009-12. doi: 10.1021/np100421v. Epub 2010 Dec 7.

PMID:
21138242
15.

Natural product derivatives with bactericidal activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis.

Phillips JB, Smith AE, Kusche BR, Bessette BA Jr, Swain PW 3rd, Bergmeier SC, McMills MC, Wright DL, Priestley ND.

Bioorg Med Chem Lett. 2010 Oct 1;20(19):5936-8. doi: 10.1016/j.bmcl.2010.06.146. Epub 2010 Jul 7.

16.

Alternating pattern of stereochemistry in the nonactin macrocycle is required for antibacterial activity and efficient ion binding.

Kusche BR, Smith AE, McGuirl MA, Priestley ND.

J Am Chem Soc. 2009 Dec 2;131(47):17155-65. doi: 10.1021/ja9050235.

17.

In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.

Paulsen JL, Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC.

Bioorg Med Chem. 2009 Jul 15;17(14):4866-72. doi: 10.1016/j.bmc.2009.06.021. Epub 2009 Jun 17.

18.

Nonactin biosynthesis: setting limits on what can be achieved with precursor-directed biosynthesis.

Kusche BR, Phillips JB, Priestley ND.

Bioorg Med Chem Lett. 2009 Feb 15;19(4):1233-5. doi: 10.1016/j.bmcl.2008.12.096. Epub 2008 Dec 30.

19.

Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors.

Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC.

Chem Biol Drug Des. 2009 Jan;73(1):62-74. doi: 10.1111/j.1747-0285.2008.00745.x.

20.

Synthetic and crystallographic studies of a new inhibitor series targeting Bacillus anthracis dihydrofolate reductase.

Beierlein JM, Frey KM, Bolstad DB, Pelphrey PM, Joska TM, Smith AE, Priestley ND, Wright DL, Anderson AC.

J Med Chem. 2008 Dec 11;51(23):7532-40. doi: 10.1021/jm800776a.

21.

Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase.

Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC.

Chem Biol. 2008 Sep 22;15(9):990-6. doi: 10.1016/j.chembiol.2008.07.013.

22.

Natural products in parallel synthesis: triazole libraries of nonactic acid.

Luesse SB, Wells G, Nayek A, Smith AE, Kusche BR, Bergmeier SC, McMills MC, Priestley ND, Wright DL.

Bioorg Med Chem Lett. 2008 Jul 15;18(14):3946-9. doi: 10.1016/j.bmcl.2008.06.020. Epub 2008 Jun 10.

PMID:
18585037
23.

Spiroiminodihydantoin as an oxo-atom transfer product of 8-oxo-2'-deoxyguanosine oxidation by chromium(V).

Slade PG, Priestley ND, Sugden KD.

Org Lett. 2007 Oct 25;9(22):4411-4. Epub 2007 Oct 4.

PMID:
17915881
24.

Lipase-mediated purification of methyl nonactate, an important natural product building block for diversity-oriented synthesis.

Dinges JM, Bessette BA Jr, Cox JE, Redder CR, Priestley ND.

Biotechnol Prog. 2006 Sep-Oct;22(5):1354-7.

PMID:
17022674
25.
26.

Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions.

Nikodinovic J, Dinges JM, Bergmeier SC, McMills MC, Wright DL, Priestley ND.

Org Lett. 2006 Feb 2;8(3):443-5.

PMID:
16435855
27.
28.

The assessment of executive functions: coming out of the office.

Manchester D, Priestley N, Jackson H.

Brain Inj. 2004 Nov;18(11):1067-81. Review.

PMID:
15545205
29.

Nonactin biosynthesis: the initial committed step is the condensation of acetate (malonate) and succinate.

Nelson ME, Priestley ND.

J Am Chem Soc. 2002 Mar 27;124(12):2894-902.

PMID:
11902879
31.

Intellectual, mnemonic, and frontal functions in dementia with Lewy bodies: A comparison with early and advanced Parkinson's disease.

Downes JJ, Priestley NM, Doran M, Ferran J, Ghadiali E, Cooper P.

Behav Neurol. 1998;11(3):173-183.

PMID:
11568418
32.
33.
34.

Nonactin biosynthesis: the potential nonactin biosynthesis gene cluster contains type II polyketide synthase-like genes.

Walczak RJ, Woo AJ, Strohl WR, Priestley ND.

FEMS Microbiol Lett. 2000 Feb 1;183(1):171-5.

35.

Nonactin biosynthesis: the product of nonS catalyzes the formation of the furan ring of nonactic acid.

Woo AJ, Strohl WR, Priestley ND.

Antimicrob Agents Chemother. 1999 Jul;43(7):1662-8.

36.

A free energy calculation can be used to predict K(+)-binding constants for new macrotetrolide antibiotics.

Lee JW, Priestley ND.

Bioorg Med Chem Lett. 1998 Jul 7;8(13):1725-8.

PMID:
9873423
37.

Intellectual, mnemonic, and frontal functions in dementia with Lewy bodies: A comparison with early and advanced Parkinson's disease.

Downes JJ, Priestley NM, Doran M, Ferran J, Ghadiali E, Cooper P.

Behav Neurol. 1999 Jan 1;11(3):173-83.

PMID:
22387597
39.
40.
41.

Efficient synthesis of radiolabeled propionyl-coenzyme A and acetyl-coenzyme A.

Rajgarhia VB, Priestley ND, Strohl WR.

Anal Biochem. 1995 Jan 1;224(1):159-62.

PMID:
7710064
42.

Preservation of priming for interactive context in amnesics.

Priestley NM, Mayes AR.

Cortex. 1992 Dec;28(4):555-74.

PMID:
1478084
43.

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