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Items: 32


Erratum for DeMarco et al., "Determination of [11C]Rifampin Pharmacokinetics within Mycobacterium tuberculosis-Infected Mice by Using Dynamic Positron Emission Tomography Bioimaging".

DeMarco VP, Ordonez AA, Klunk M, Prideaux B, Wang H, Zhang Z, Tonge PJ, Dannals RF, Holt DP, Lee CKK, Weinstein EA, Dartois V, Dooley KE, Jain SK.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e01368-19. doi: 10.1128/AAC.01368-19. Print 2019 Sep. No abstract available.


Tissue Distribution and Penetration of Isavuconazole at the Site of Infection in Experimental Invasive Aspergillosis in Mice with Underlying Chronic Granulomatous Disease.

Lee A, Prideaux B, Lee MH, Zimmerman M, Dolgov E, Perlin DS, Zhao Y.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00524-19. doi: 10.1128/AAC.00524-19. Print 2019 Jun.


Beyond tissue concentrations: antifungal penetration at the site of infection.

Zhao Y, Prideaux B, Baistrocchi S, Sheppard DC, Perlin DS.

Med Mycol. 2019 Apr 1;57(Supplement_2):S161-S167. doi: 10.1093/mmy/myy067. Review.


Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations.

Sarathy J, Blanc L, Alvarez-Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Zimmerman M, Kaya F, Ho Liang HP, Prideaux B, Dietzold J, Salgame P, Savic RM, Linderman J, Kirschner D, Pienaar E, Dartois V.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02516-18. doi: 10.1128/AAC.02516-18. Print 2019 May.


High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types.

Blanc L, Daudelin IB, Podell BK, Chen PY, Zimmerman M, Martinot AJ, Savic RM, Prideaux B, Dartois V.

Elife. 2018 Nov 14;7. pii: e41115. doi: 10.7554/eLife.41115.


Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific.

Guerrini V, Prideaux B, Blanc L, Bruiners N, Arrigucci R, Singh S, Ho-Liang HP, Salamon H, Chen PY, Lakehal K, Subbian S, O'Brien P, Via LE, Barry CE 3rd, Dartois V, Gennaro ML.

PLoS Pathog. 2018 Aug 30;14(8):e1007223. doi: 10.1371/journal.ppat.1007223. eCollection 2018 Aug.


Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle.

Bartelink IH, Jones EF, Shahidi-Latham SK, Lee PRE, Zheng Y, Vicini P, van 't Veer L, Wolf D, Iagaru A, Kroetz DL, Prideaux B, Cilliers C, Thurber GM, Wimana Z, Gebhart G.

Clin Pharmacol Ther. 2019 Jul;106(1):148-163. doi: 10.1002/cpt.1211. Epub 2018 Oct 6. Review.


Impact of immunopathology on the antituberculous activity of pyrazinamide.

Blanc L, Sarathy JP, Alvarez Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Sacchettini J, Savic RM, Gengenbacher M, Podell BK, Prideaux B, Ioerger T, Dick T, Dartois V.

J Exp Med. 2018 Aug 6;215(8):1975-1986. doi: 10.1084/jem.20180518. Epub 2018 Jul 17.


Imaging and spatially resolved quantification of drug distribution in tissues by mass spectrometry.

Prideaux B, Lenaerts A, Dartois V.

Curr Opin Chem Biol. 2018 Jun;44:93-100. doi: 10.1016/j.cbpa.2018.05.007. Epub 2018 Jun 27. Review.


Visualization of Mycobacterial Biomarkers and Tuberculosis Drugs in Infected Tissue by MALDI-MS Imaging.

Blanc L, Lenaerts A, Dartois V, Prideaux B.

Anal Chem. 2018 May 15;90(10):6275-6282. doi: 10.1021/acs.analchem.8b00985. Epub 2018 Apr 26.


Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data.

Rifat D, Prideaux B, Savic RM, Urbanowski ME, Parsons TL, Luna B, Marzinke MA, Ordonez AA, DeMarco VP, Jain SK, Dartois V, Bishai WR, Dooley KE.

Sci Transl Med. 2018 Apr 4;10(435). pii: eaai7786. doi: 10.1126/scitranslmed.aai7786.


Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.

Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, Pawlowska N, Thomas S, Dhawan M, Aggarwal R, Munster PN, Esserman LJ, Ruan W, Wu AHB, Yee D, Dartois V, Savic RM, Wolf DM, van 't Veer L.

Breast Cancer Res. 2017 Sep 11;19(1):107. doi: 10.1186/s13058-017-0896-4.


Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.

Pienaar E, Sarathy J, Prideaux B, Dietzold J, Dartois V, Kirschner DE, Linderman JJ.

PLoS Comput Biol. 2017 Aug 17;13(8):e1005650. doi: 10.1371/journal.pcbi.1005650. eCollection 2017 Aug.


Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-abdominal Abscess Model.

Zhao Y, Prideaux B, Nagasaki Y, Lee MH, Chen PY, Blanc L, Ho H, Clancy CJ, Nguyen MH, Dartois V, Perlin DS.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e01009-17. doi: 10.1128/AAC.01009-17. Print 2017 Oct.


Ethambutol Partitioning in Tuberculous Pulmonary Lesions Explains Its Clinical Efficacy.

Zimmerman M, Lestner J, Prideaux B, O'Brien P, Dias-Freedman I, Chen C, Dietzold J, Daudelin I, Kaya F, Blanc L, Chen PY, Park S, Salgame P, Sarathy J, Dartois V.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00924-17. doi: 10.1128/AAC.00924-17. Print 2017 Sep.


Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice.

Irwin SM, Prideaux B, Lyon ER, Zimmerman MD, Brooks EJ, Schrupp CA, Chen C, Reichlen MJ, Asay BC, Voskuil MI, Nuermberger EL, Andries K, Lyons MA, Dartois V, Lenaerts AJ.

ACS Infect Dis. 2016 Apr 8;2(4):251-267. Epub 2016 Feb 24.


Inflammatory signaling in human tuberculosis granulomas is spatially organized.

Marakalala MJ, Raju RM, Sharma K, Zhang YJ, Eugenin EA, Prideaux B, Daudelin IB, Chen PY, Booty MG, Kim JH, Eum SY, Via LE, Behar SM, Barry CE 3rd, Mann M, Dartois V, Rubin EJ.

Nat Med. 2016 May;22(5):531-8. doi: 10.1038/nm.4073. Epub 2016 Apr 4.


Statin adjunctive therapy shortens the duration of TB treatment in mice.

Dutta NK, Bruiners N, Pinn ML, Zimmerman MD, Prideaux B, Dartois V, Gennaro ML, Karakousis PC.

J Antimicrob Chemother. 2016 Jun;71(6):1570-7. doi: 10.1093/jac/dkw014. Epub 2016 Feb 21.


The association between sterilizing activity and drug distribution into tuberculosis lesions.

Prideaux B, Via LE, Zimmerman MD, Eum S, Sarathy J, O'Brien P, Chen C, Kaya F, Weiner DM, Chen PY, Song T, Lee M, Shim TS, Cho JS, Kim W, Cho SN, Olivier KN, Barry CE 3rd, Dartois V.

Nat Med. 2015 Oct;21(10):1223-7. doi: 10.1038/nm.3937. Epub 2015 Sep 7.


Can the KG1 cell line be used as a model of dendritic cells and discriminate the sensitising potential of chemicals?

Curtis A, Morton J, Fraser S, Harding AH, Prideaux B, Clench M, Warren ND, Evans GS.

Toxicol Lett. 2015 Nov 19;239(1):32-40. doi: 10.1016/j.toxlet.2015.08.006. Epub 2015 Aug 7.


Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling.

Prideaux B, ElNaggar MS, Zimmerman M, Wiseman JM, Li X, Dartois V.

Int J Mass Spectrom. 2015 Feb 1;377:699-708.


Determination of [11C]rifampin pharmacokinetics within Mycobacterium tuberculosis-infected mice by using dynamic positron emission tomography bioimaging.

DeMarco VP, Ordonez AA, Klunk M, Prideaux B, Wang H, Zhuo Z, Tonge PJ, Dannals RF, Holt DP, Lee CK, Weinstein EA, Dartois V, Dooley KE, Jain SK.

Antimicrob Agents Chemother. 2015 Sep;59(9):5768-74. doi: 10.1128/AAC.01146-15. Epub 2015 Jul 13. Erratum in: Antimicrob Agents Chemother. 2019 Aug 23;63(9):.


Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives.

Via LE, Savic R, Weiner DM, Zimmerman MD, Prideaux B, Irwin SM, Lyon E, O'Brien P, Gopal P, Eum S, Lee M, Lanoix JP, Dutta NK, Shim T, Cho JS, Kim W, Karakousis PC, Lenaerts A, Nuermberger E, Barry CE 3rd, Dartois V.

ACS Infect Dis. 2015 May 8;1(5):203-214.


Software tools of the Computis European project to process mass spectrometry images.

Robbe MF, Both JP, Prideaux B, Klinkert I, Picaud V, Schramm T, Hester A, Guevara V, Stoeckli M, Roempp A, Heeren RM, Spengler B, Gala O, Haan S.

Eur J Mass Spectrom (Chichester). 2014;20(5):351-60. Erratum in: Eur J Mass Spectrom (Chichester). 2014;20(6):487.


Mass spectrometry imaging of biological tissue: an approach for multicenter studies.

Römpp A, Both JP, Brunelle A, Heeren RM, Laprévote O, Prideaux B, Seyer A, Spengler B, Stoeckli M, Smith DF.

Anal Bioanal Chem. 2015 Mar;407(8):2329-35. doi: 10.1007/s00216-014-8410-7. Epub 2015 Jan 10.


Evaluation of sparfloxacin distribution by mass spectrometry imaging in a phototoxicity model.

Boudon SM, Morandi G, Prideaux B, Staab D, Junker U, Odermatt A, Stoeckli M, Bauer D.

J Am Soc Mass Spectrom. 2014 Oct;25(10):1803-9. doi: 10.1007/s13361-014-0947-3. Epub 2014 Jul 8.


Corrigendum to "Software tools of the Computis European project to process mass spectrometry images an experimental and theoretical study" [Eur. J. Mass Spectrom. 20(5), 351-360 (2014)].

Robbe MF, Both JP, Prideaux B, Klinkert I, Picaud V, Schramm T, Hester A, Guevara V, Stoeckli M, Roempp A, Heeren RM, Spengler B, Gal O, Haan S.

Eur J Mass Spectrom (Chichester). 2014;20(6):487. doi: 10.1255/ejms.1315. No abstract available.


Mass spectrometry imaging for drug distribution studies.

Prideaux B, Stoeckli M.

J Proteomics. 2012 Aug 30;75(16):4999-5013. doi: 10.1016/j.jprot.2012.07.028. Epub 2012 Jul 25. Review.


High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions.

Prideaux B, Dartois V, Staab D, Weiner DM, Goh A, Via LE, Barry CE 3rd, Stoeckli M.

Anal Chem. 2011 Mar 15;83(6):2112-8. doi: 10.1021/ac1029049. Epub 2011 Feb 18.


Applications of MALDI-MSI to pharmaceutical research.

Prideaux B, Staab D, Stoeckli M.

Methods Mol Biol. 2010;656:405-13. doi: 10.1007/978-1-60761-746-4_23.


Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development.

Solon EG, Schweitzer A, Stoeckli M, Prideaux B.

AAPS J. 2010 Mar;12(1):11-26. doi: 10.1208/s12248-009-9158-4. Epub 2009 Nov 17. Review. Erratum in: AAPS J. 2010 Mar;12(1):107.

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