Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 742

1.

An unusual cause of adrenal insufficiency and bilateral adrenal masses.

Tee SA, Gan EH, Kanaan MZ, Price DA, Hoare T, Pearce SHS.

Endocrinol Diabetes Metab Case Rep. 2018 Jul 6;2018. pii: 18-0030. doi: 10.1530/EDM-18-0030. eCollection 2018.

2.

Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness.

Costa Del Amo P, Lahoz-Beneytez J, Boelen L, Ahmed R, Miners KL, Zhang Y, Roger L, Jones RE, Marraco SAF, Speiser DE, Baird DM, Price DA, Ladell K, Macallan D, Asquith B.

PLoS Biol. 2018 Jun 22;16(6):e2005523. doi: 10.1371/journal.pbio.2005523. eCollection 2018 Jun.

3.

Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes.

Powell WE, Hanna SJ, Hocter CN, Robinson E, Davies J, Dunseath GJ, Luzio S, Farewell D, Wen L, Dayan CM, Price DA, Ladell K, Wong FS.

Diabetologia. 2018 Jun 7. doi: 10.1007/s00125-018-4651-x. [Epub ahead of print]

PMID:
29881878
4.

Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue.

Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR.

Sci Immunol. 2018 Jun 1;3(24). pii: eaar4526. doi: 10.1126/sciimmunol.aar4526.

PMID:
29858286
5.

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity.

Edwards ESJ, Bier J, Cole TS, Wong M, Hsu P, Berglund LJ, Boztug K, Lau A, Gostick E, Price DA, O'Sullivan M, Meyts I, Choo S, Gray P, Holland SM, Deenick EK, Uzel G, Tangye SG.

J Allergy Clin Immunol. 2018 May 22. pii: S0091-6749(18)30702-4. doi: 10.1016/j.jaci.2018.04.030. [Epub ahead of print]

PMID:
29800648
6.

Five-Year Graft Survival of Descemet Membrane Endothelial Keratoplasty (EK) versus Descemet Stripping EK and the Effect of Donor Sex Matching.

Price DA, Kelley M, Price FW Jr, Price MO.

Ophthalmology. 2018 May 3. pii: S0161-6420(17)33820-4. doi: 10.1016/j.ophtha.2018.03.050. [Epub ahead of print]

PMID:
29731147
7.

Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a Treatment for Cardiac Fibrosis.

Menhaji-Klotz E, Hesp KD, Londregan AT, Kalgutkar AS, Piotrowski DW, Boehm M, Song K, Ryder T, Beaumont K, Jones RM, Atkinson K, Brown JA, Litchfield J, Xiao J, Canterbury DP, Burford K, Thuma BA, Limberakis C, Jiao W, Bagley SW, Agarwal S, Crowell D, Pazdziorko S, Ward J, Price DA, Clerin V.

J Med Chem. 2018 Apr 26;61(8):3685-3696. doi: 10.1021/acs.jmedchem.8b00190. Epub 2018 Apr 17.

PMID:
29627981
8.

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

Wun KS, Reijneveld JF, Cheng TY, Ladell K, Uldrich AP, Le Nours J, Miners KL, McLaren JE, Grant EJ, Haigh OL, Watkins TS, Suliman S, Iwany S, Jimenez J, Calderon R, Tamara KL, Leon SR, Murray MB, Mayfield JA, Altman JD, Purcell AW, Miles JJ, Godfrey DI, Gras S, Price DA, Van Rhijn I, Moody DB, Rossjohn J.

Nat Immunol. 2018 Apr;19(4):397-406. doi: 10.1038/s41590-018-0065-7. Epub 2018 Mar 12.

PMID:
29531339
9.

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.

Miles JJ, Tan MP, Dolton G, Edwards ES, Galloway SA, Laugel B, Clement M, Makinde J, Ladell K, Matthews KK, Watkins TS, Tungatt K, Wong Y, Lee HS, Clark RJ, Pentier JM, Attaf M, Lissina A, Ager A, Gallimore A, Rizkallah PJ, Gras S, Rossjohn J, Burrows SR, Cole DK, Price DA, Sewell AK.

J Clin Invest. 2018 Apr 2;128(4):1569-1580. doi: 10.1172/JCI91512. Epub 2018 Mar 12.

10.

Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.

Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M.

J Clin Invest. 2018 May 1;128(5):1903-1912. doi: 10.1172/JCI98463. Epub 2018 Apr 3.

11.

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.

Culina S, Lalanne AI, Afonso G, Cerosaletti K, Pinto S, Sebastiani G, Kuranda K, Nigi L, Eugster A, Østerbye T, Maugein A, McLaren JE, Ladell K, Larger E, Beressi JP, Lissina A, Appay V, Davidson HW, Buus S, Price DA, Kuhn M, Bonifacio E, Battaglia M, Caillat-Zucman S, Dotta F, Scharfmann R, Kyewski B, Mallone R; ImMaDiab Study Group, Carel JC, Tubiana-Rufi N, Martinerie L, Poidvin A, JacqzAigrain E, Corvez L, Berruer V, Gautier JF, Baz B, Haddadi N, Andreelli F, Amouyal C, Jaqueminet S, Bourron O, Dasque E, Hartemann A, Lemoine-Yazigi A, Dubois-Laforgue D, Travert F, Feron M, Rolland P, Vignali V, Marre M, Chanson P, Briet C, Guillausseau PJ, Ait-Bachir L, Collet C, Beziaud F, Desforges-Bullet V, Petit-Aubert G, Christin-Maitre S, Fève B, Vatier C, Bourcigaux N, Lautridou C, Lahlou N, Bakouboula P, Elie C, Morel H, Treluyer JM, Gagnerault MC, Maillard C, Jones A.

Sci Immunol. 2018 Feb 2;3(20). pii: eaao4013. doi: 10.1126/sciimmunol.aao4013.

PMID:
29429978
12.

CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin.

McCully ML, Ladell K, Andrews R, Jones RE, Miners KL, Roger L, Baird DM, Cameron MJ, Jessop ZM, Whitaker IS, Davies EL, Price DA, Moser B.

J Immunol. 2018 Mar 1;200(5):1639-1650. doi: 10.4049/jimmunol.1701377. Epub 2018 Feb 2.

13.

Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions.

Lissina A, McLaren JE, Ilander M, Andersson EI, Lewis CS, Clement M, Herman A, Ladell K, Llewellyn-Lacey S, Miners KL, Gostick E, Melenhorst JJ, Barrett AJ, Price DA, Mustjoki S, Wooldridge L.

Sci Rep. 2018 Feb 7;8(1):2534. doi: 10.1038/s41598-017-18062-x.

14.

The unholy trinity of human herpesvirus 8-associated malignancy in a person living with HIV-1.

Duncan CJA, Charlton FG, Bower M, Price DA.

AIDS. 2018 Jan 28;32(3):404-406. doi: 10.1097/QAD.0000000000001719. No abstract available.

PMID:
29309348
15.

HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue.

Reuter MA, Del Rio Estrada PM, Buggert M, Petrovas C, Ferrando-Martinez S, Nguyen S, Sada Japp A, Ablanedo-Terrazas Y, Rivero-Arrieta A, Kuri-Cervantes L, Gunzelman HM, Gostick E, Price DA, Koup RA, Naji A, Canaday DH, Reyes-Terán G, Betts MR.

Cell Rep. 2017 Dec 19;21(12):3458-3470. doi: 10.1016/j.celrep.2017.11.075.

16.

Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial.

Thwaites GE, Scarborough M, Szubert A, Nsutebu E, Tilley R, Greig J, Wyllie SA, Wilson P, Auckland C, Cairns J, Ward D, Lal P, Guleri A, Jenkins N, Sutton J, Wiselka M, Armando GR, Graham C, Chadwick PR, Barlow G, Gordon NC, Young B, Meisner S, McWhinney P, Price DA, Harvey D, Nayar D, Jeyaratnam D, Planche T, Minton J, Hudson F, Hopkins S, Williams J, Török ME, Llewelyn MJ, Edgeworth JD, Walker AS; United Kingdom Clinical Infection Research Group (UKCIRG).

Lancet. 2018 Feb 17;391(10121):668-678. doi: 10.1016/S0140-6736(17)32456-X. Epub 2017 Dec 14.

17.

Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop.

James EA, Abreu JRF, McGinty JW, Odegard JM, Fillié YE, Hocter CN, Culina S, Ladell K, Price DA, Alkanani A, Rihanek M, Fitzgerald-Miller L, Skowera A, Speake C, Gottlieb P, Davidson HW, Wong FS, Roep B, Mallone R; Immunology of Diabetes Society T Cell Workshop Committee.

Diabetologia. 2018 Mar;61(3):658-670. doi: 10.1007/s00125-017-4508-8. Epub 2017 Dec 1.

PMID:
29196783
18.

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.

Van Braeckel-Budimir N, Gras S, Ladell K, Josephs TM, Pewe L, Urban SL, Miners KL, Farenc C, Price DA, Rossjohn J, Harty JT.

Immunity. 2017 Nov 21;47(5):835-847.e4. doi: 10.1016/j.immuni.2017.10.013. Epub 2017 Nov 14.

PMID:
29150238
19.

Discovery of Potent and Orally Bioavailable Macrocyclic Peptide-Peptoid Hybrid CXCR7 Modulators.

Boehm M, Beaumont K, Jones R, Kalgutkar AS, Zhang L, Atkinson K, Bai G, Brown JA, Eng H, Goetz GH, Holder BR, Khunte B, Lazzaro S, Limberakis C, Ryu S, Shapiro MJ, Tylaska L, Yan J, Turner R, Leung SSF, Ramaseshan M, Price DA, Liras S, Jacobson MP, Earp DJ, Lokey RS, Mathiowetz AM, Menhaji-Klotz E.

J Med Chem. 2017 Dec 14;60(23):9653-9663. doi: 10.1021/acs.jmedchem.7b01028. Epub 2017 Oct 30.

20.

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity.

Shugay M, Bagaev DV, Zvyagin IV, Vroomans RM, Crawford JC, Dolton G, Komech EA, Sycheva AL, Koneva AE, Egorov ES, Eliseev AV, Van Dyk E, Dash P, Attaf M, Rius C, Ladell K, McLaren JE, Matthews KK, Clemens EB, Douek DC, Luciani F, van Baarle D, Kedzierska K, Kesmir C, Thomas PG, Price DA, Sewell AK, Chudakov DM.

Nucleic Acids Res. 2018 Jan 4;46(D1):D419-D427. doi: 10.1093/nar/gkx760.

21.

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response.

Culshaw A, Ladell K, Gras S, McLaren JE, Miners KL, Farenc C, van den Heuvel H, Gostick E, Dejnirattisai W, Wangteeraprasert A, Duangchinda T, Chotiyarnwong P, Limpitikul W, Vasanawathana S, Malasit P, Dong T, Rossjohn J, Mongkolsapaya J, Price DA, Screaton GR.

Nat Immunol. 2017 Nov;18(11):1228-1237. doi: 10.1038/ni.3850. Epub 2017 Sep 25.

22.

Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK).

Huard K, Ahn K, Amor P, Beebe DA, Borzilleri KA, Chrunyk BA, Coffey SB, Cong Y, Conn EL, Culp JS, Dowling MS, Gorgoglione MF, Gutierrez JA, Knafels JD, Lachapelle EA, Pandit J, Parris KD, Perez S, Pfefferkorn JA, Price DA, Raymer B, Ross TT, Shavnya A, Smith AC, Subashi TA, Tesz GJ, Thuma BA, Tu M, Weaver JD, Weng Y, Withka JM, Xing G, Magee TV.

J Med Chem. 2017 Sep 28;60(18):7835-7849. doi: 10.1021/acs.jmedchem.7b00947. Epub 2017 Sep 11.

PMID:
28853885
23.

Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia.

Anguille S, Van de Velde AL, Smits EL, Van Tendeloo VF, Juliusson G, Cools N, Nijs G, Stein B, Lion E, Van Driessche A, Vandenbosch I, Verlinden A, Gadisseur AP, Schroyens WA, Muylle L, Vermeulen K, Maes MB, Deiteren K, Malfait R, Gostick E, Lammens M, Couttenye MM, Jorens P, Goossens H, Price DA, Ladell K, Oka Y, Fujiki F, Oji Y, Sugiyama H, Berneman ZN.

Blood. 2017 Oct 12;130(15):1713-1721. doi: 10.1182/blood-2017-04-780155. Epub 2017 Aug 22.

24.

Missed opportunities to diagnose syphilis prior to the development of sight-losing uveitis.

Widdrington J, Ashfaq I, Puvaneswaran B, Ong EL, Schwab U, Price DA, Schmid ML, Pandit R.

J R Coll Physicians Edinb. 2017 Jun;47(2):129-134. doi: 10.4997/JRCPE.2017.204.

PMID:
28675181
25.

Curtailed T-cell activation curbs effector differentiation and generates CD8+ T cells with a naturally-occurring memory stem cell phenotype.

Zanon V, Pilipow K, Scamardella E, De Paoli F, De Simone G, Price DA, Martinez Usatorre A, Romero P, Mavilio D, Roberto A, Lugli E.

Eur J Immunol. 2017 Sep;47(9):1468-1476. doi: 10.1002/eji.201646732. Epub 2017 Jul 28.

26.

Optimizing the combination insulin bolus split for a high-fat, high-protein meal in children and adolescents using insulin pump therapy.

Lopez PE, Smart CE, McElduff P, Foskett DC, Price DA, Paterson MA, King BR.

Diabet Med. 2017 Oct;34(10):1380-1384. doi: 10.1111/dme.13392. Epub 2017 Jul 25.

PMID:
28574182
27.

Diagnostic accuracy and cost analysis of the Alere™ i Influenza A&B near-patient test using throat swabs.

Davis S, Allen AJ, O'Leary R, Power M, Price DA, Simpson AJ, Tunbridge A, Vale L, Whiteside M, Evans C, Raza M.

J Hosp Infect. 2017 Nov;97(3):301-309. doi: 10.1016/j.jhin.2017.05.017. Epub 2017 May 27.

PMID:
28558954
28.

The pentameric complex drives immunologically covert cell-cell transmission of wild-type human cytomegalovirus.

Murrell I, Bedford C, Ladell K, Miners KL, Price DA, Tomasec P, Wilkinson GWG, Stanton RJ.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6104-6109. doi: 10.1073/pnas.1704809114. Epub 2017 May 22.

29.

Using perimetric data to estimate ganglion cell loss for detecting progression of glaucoma: a comparison of models.

Price DA, Swanson WH, Horner DG.

Ophthalmic Physiol Opt. 2017 Jul;37(4):409-419. doi: 10.1111/opo.12378. Epub 2017 Apr 25.

30.

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses.

Gutjahr A, Papagno L, Nicoli F, Lamoureux A, Vernejoul F, Lioux T, Gostick E, Price DA, Tiraby G, Perouzel E, Appay V, Verrier B, Paul S.

J Immunol. 2017 Jun 1;198(11):4205-4209. doi: 10.4049/jimmunol.1602131. Epub 2017 Apr 21.

31.

Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.

Chen HC, Joalland N, Bridgeman JS, Alchami FS, Jarry U, Khan MWA, Piggott L, Shanneik Y, Li J, Herold MJ, Herrmann T, Price DA, Gallimore AM, Clarkson RW, Scotet E, Moser B, Eberl M.

Immunol Cell Biol. 2017 Aug;95(7):620-629. doi: 10.1038/icb.2017.21. Epub 2017 Mar 30.

32.

Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response.

Smith C, Lee V, Schuessler A, Beagley L, Rehan S, Tsang J, Li V, Tiu R, Smith D, Neller MA, Matthews KK, Gostick E, Price DA, Burrows J, Boyle GM, Chua D, Panizza B, Porceddu SV, Nicholls J, Kwong D, Khanna R.

Oncoimmunology. 2017 Jan 4;6(2):e1273311. doi: 10.1080/2162402X.2016.1273311. eCollection 2017.

33.

Tenofovir disoproxil fumarate-associated renal tubular dysfunction: noninvasive assessment of mitochondrial injury.

Samuels R, Bayerri CR, Sayer JA, Price DA, Payne BAI.

AIDS. 2017 Jun 1;31(9):1297-1301. doi: 10.1097/QAD.0000000000001466.

34.

Comparative pharmacokinetic profile of cyclosporine (CsA) with a decapeptide and a linear analogue.

Price DA, Eng H, Farley KA, Goetz GH, Huang Y, Jiao Z, Kalgutkar AS, Kablaoui NM, Khunte B, Liras S, Limberakis C, Mathiowetz AM, Ruggeri RB, Quan JM, Yang Z.

Org Biomol Chem. 2017 Mar 28;15(12):2501-2506. doi: 10.1039/c7ob00096k. Epub 2017 Mar 7.

PMID:
28266673
35.

Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance.

Davey MS, Willcox CR, Joyce SP, Ladell K, Kasatskaya SA, McLaren JE, Hunter S, Salim M, Mohammed F, Price DA, Chudakov DM, Willcox BE.

Nat Commun. 2017 Mar 1;8:14760. doi: 10.1038/ncomms14760.

36.

Does efavirenz replacement improve neurological function in treated HIV infection?

Payne B, Chadwick TJ, Blamire A, Anderson KN, Parikh J, Qian J, Hynes AM, Wilkinson J, Price DA; Efficacy of Switch to Lopinavir/Ritonavir in Improving Cognitive Function in Efavirenz-treated Patients (SLICE) study team.

HIV Med. 2017 Oct;18(9):690-695. doi: 10.1111/hiv.12503. Epub 2017 Mar 1.

37.

Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor.

Sanhueza CA, Baksh MM, Thuma B, Roy MD, Dutta S, Préville C, Chrunyk BA, Beaumont K, Dullea R, Ammirati M, Liu S, Gebhard D, Finley JE, Salatto CT, King-Ahmad A, Stock I, Atkinson K, Reidich B, Lin W, Kumar R, Tu M, Menhaji-Klotz E, Price DA, Liras S, Finn MG, Mascitti V.

J Am Chem Soc. 2017 Mar 8;139(9):3528-3536. doi: 10.1021/jacs.6b12964. Epub 2017 Feb 23.

PMID:
28230359
38.

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP.

Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20.

PMID:
28218747
39.

Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules.

Pye CR, Hewitt WM, Schwochert J, Haddad TD, Townsend CE, Etienne L, Lao Y, Limberakis C, Furukawa A, Mathiowetz AM, Price DA, Liras S, Lokey RS.

J Med Chem. 2017 Mar 9;60(5):1665-1672. doi: 10.1021/acs.jmedchem.6b01483. Epub 2017 Jan 25.

40.

Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency.

Abolhassani H, Edwards ES, Ikinciogullari A, Jing H, Borte S, Buggert M, Du L, Matsuda-Lennikov M, Romano R, Caridha R, Bade S, Zhang Y, Frederiksen J, Fang M, Bal SK, Haskologlu S, Dogu F, Tacyildiz N, Matthews HF, McElwee JJ, Gostick E, Price DA, Palendira U, Aghamohammadi A, Boisson B, Rezaei N, Karlsson AC, Lenardo MJ, Casanova JL, Hammarström L, Tangye SG, Su HC, Pan-Hammarström Q.

J Exp Med. 2017 Jan;214(1):91-106. doi: 10.1084/jem.20160849. Epub 2016 Dec 23.

41.

Amine promiscuity and toxicology analysis.

Lee EC, Steeno G, Wassermann AM, Zhang L, Shah F, Price DA.

Bioorg Med Chem Lett. 2017 Feb 1;27(3):653-657. doi: 10.1016/j.bmcl.2016.11.085. Epub 2016 Nov 29.

PMID:
28011216
42.

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux.

Ahmed R, Roger L, Costa Del Amo P, Miners KL, Jones RE, Boelen L, Fali T, Elemans M, Zhang Y, Appay V, Baird DM, Asquith B, Price DA, Macallan DC, Ladell K.

Cell Rep. 2016 Dec 13;17(11):2811-2818. doi: 10.1016/j.celrep.2016.11.037.

43.

Chiral Sulfoxide-Induced Single Turn Peptide α-Helicity.

Zhang Q, Jiang F, Zhao B, Lin H, Tian Y, Xie M, Bai G, Gilbert AM, Goetz GH, Liras S, Mathiowetz AA, Price DA, Song K, Tu M, Wu Y, Wang T, Flanagan ME, Wu YD, Li Z.

Sci Rep. 2016 Dec 9;6:38573. doi: 10.1038/srep38573.

44.

Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.

Plisson F, Hill TA, Mitchell JM, Hoang HN, de Araujo AD, Xu W, Cotterell A, Edmonds DJ, Stanton RV, Derksen DR, Loria PM, Griffith DA, Price DA, Liras S, Fairlie DP.

Eur J Med Chem. 2017 Feb 15;127:703-714. doi: 10.1016/j.ejmech.2016.10.044. Epub 2016 Oct 21.

PMID:
27823886
45.

Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies.

Clement M, Pearson JA, Gras S, van den Berg HA, Lissina A, Llewellyn-Lacey S, Willis MD, Dockree T, McLaren JE, Ekeruche-Makinde J, Gostick E, Robertson NP, Rossjohn J, Burrows SR, Price DA, Wong FS, Peakman M, Skowera A, Wooldridge L.

Sci Rep. 2016 Oct 17;6:35332. doi: 10.1038/srep35332.

46.

CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.

Dockree T, Holland CJ, Clement M, Ladell K, McLaren JE, van den Berg HA, Gostick E, L Miners K, Llewellyn-Lacey S, Bridgeman JS, Man S, Bailey M, Burrows SR, Price DA, Wooldridge L.

Immunol Cell Biol. 2017 Jan;95(1):68-76. doi: 10.1038/icb.2016.85. Epub 2016 Nov 8.

47.

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination.

Pageon SV, Tabarin T, Yamamoto Y, Ma Y, Nicovich PR, Bridgeman JS, Cohnen A, Benzing C, Gao Y, Crowther MD, Tungatt K, Dolton G, Sewell AK, Price DA, Acuto O, Parton RG, Gooding JJ, Rossy J, Rossjohn J, Gaus K.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5454-63. doi: 10.1073/pnas.1607436113. Epub 2016 Aug 29. Erratum in: Proc Natl Acad Sci U S A. 2016 Oct 17;:.

48.

Intrathecal T-cell clonal expansions in patients with multiple sclerosis.

de Paula Alves Sousa A, Johnson KR, Nicholas R, Darko S, Price DA, Douek DC, Jacobson S, Muraro PA.

Ann Clin Transl Neurol. 2016 Apr 20;3(6):422-33. doi: 10.1002/acn3.310. eCollection 2016 Jun.

49.

Purity of transferred CD8(+) T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1.

Watson HA, Dolton G, Ohme J, Ladell K, Vigar M, Wehenkel S, Hindley J, Mohammed RN, Miners K, Luckwell RA, Price DA, Matthews RJ, Ager A.

Immunol Cell Biol. 2016 Sep;94(8):802-8. doi: 10.1038/icb.2016.45. Epub 2016 Jul 19.

50.

Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.

Swedberg JE, Schroeder CI, Mitchell JM, Fairlie DP, Edmonds DJ, Griffith DA, Ruggeri RB, Derksen DR, Loria PM, Price DA, Liras S, Craik DJ.

J Biol Chem. 2016 Jul 22;291(30):15778-87. doi: 10.1074/jbc.M116.724542. Epub 2016 May 10.

Supplemental Content

Loading ...
Support Center