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HJURP knockdown disrupts clonogenic capacity and increases radiation-induced cell death of glioblastoma cells.

Serafim RB, Cardoso C, Di Cristofaro LFM, Pienna Soares C, Araújo Silva W Jr, Espreafico EM, Paçó-Larson ML, Price BD, Valente V.

Cancer Gene Ther. 2019 May 29. doi: 10.1038/s41417-019-0103-0. [Epub ahead of print]


Multiple Roles for Mono- and Poly(ADP-Ribose) in Regulating Stress Responses.

Qi H, Price BD, Day TA.

Trends Genet. 2019 Feb;35(2):159-172. doi: 10.1016/j.tig.2018.12.002. Epub 2018 Dec 27. Review.


Human CHD1 is required for early DNA-damage signaling and is uniquely regulated by its N terminus.

Zhou J, Li J, Serafim RB, Ketchum S, Ferreira CG, Liu JC, Coe KA, Price BD, Yusufzai T.

Nucleic Acids Res. 2018 May 4;46(8):3891-3905. doi: 10.1093/nar/gky128.


Spatially restricted loading of BRD2 at DNA double-strand breaks protects H4 acetylation domains and promotes DNA repair.

Gursoy-Yuzugullu O, Carman C, Price BD.

Sci Rep. 2017 Oct 10;7(1):12921. doi: 10.1038/s41598-017-13036-5.


Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastoma.

Ströbel T, Madlener S, Tuna S, Vose S, Lagerweij T, Wurdinger T, Vierlinger K, Wöhrer A, Price BD, Demple B, Saydam O, Saydam N.

Sci Rep. 2017 Aug 29;7(1):9674. doi: 10.1038/s41598-017-10013-w.


The tale of a tail: histone H4 acetylation and the repair of DNA breaks.

Dhar S, Gursoy-Yuzugullu O, Parasuram R, Price BD.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731). pii: 20160284. doi: 10.1098/rstb.2016.0284. Review.


Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.

Day TA, Layer JV, Cleary JP, Guha S, Stevenson KE, Tivey T, Kim S, Schinzel AC, Izzo F, Doench J, Root DE, Hahn WC, Price BD, Weinstock DM.

Nat Commun. 2017 Jun 13;8:15918. doi: 10.1038/ncomms15918.


KDM5A demethylase: Erasing histone modifications to promote repair of DNA breaks.

Price BD.

J Cell Biol. 2017 Jul 3;216(7):1871-1873. doi: 10.1083/jcb.201705005. Epub 2017 Jun 1.


PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.

Day TA, Layer JV, Cleary JP, Guha S, Stevenson KE, Tivey T, Kim S, Schinzel AC, Izzo F, Doench J, Root DE, Hahn WC, Price BD, Weinstock DM.

Nat Commun. 2017 Apr 27;8:15110. doi: 10.1038/ncomms15110. Erratum in: Nat Commun. 2017 Jun 13;8:15918.


Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity.

Gursoy-Yuzugullu O, Carman C, Serafim RB, Myronakis M, Valente V, Price BD.

Oncotarget. 2017 Apr 11;8(15):24518-24532. doi: 10.18632/oncotarget.15543.


Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA Breaks.

Gursoy-Yuzugullu O, House N, Price BD.

J Mol Biol. 2016 May 8;428(9 Pt B):1846-60. doi: 10.1016/j.jmb.2015.11.021. Epub 2015 Nov 26. Review.


Histone chaperone Anp32e removes H2A.Z from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair.

Gursoy-Yuzugullu O, Ayrapetov MK, Price BD.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7507-12. doi: 10.1073/pnas.1504868112. Epub 2015 Jun 1. Erratum in: Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3750.


DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin.

Ayrapetov MK, Gursoy-Yuzugullu O, Xu C, Xu Y, Price BD.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9169-74. doi: 10.1073/pnas.1403565111. Epub 2014 Jun 9.


Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance.

Madlener S, Ströbel T, Vose S, Saydam O, Price BD, Demple B, Saydam N.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17844-9. doi: 10.1073/pnas.1304784110. Epub 2013 Oct 14.


FANCD2 activates transcription of TAp63 and suppresses tumorigenesis.

Park E, Kim H, Kim JM, Primack B, Vidal-Cardenas S, Xu Y, Price BD, Mills AA, D'Andrea AD.

Mol Cell. 2013 Jun 27;50(6):908-18. doi: 10.1016/j.molcel.2013.05.017.


Chromatin remodeling at DNA double-strand breaks.

Price BD, D'Andrea AD.

Cell. 2013 Mar 14;152(6):1344-54. doi: 10.1016/j.cell.2013.02.011. Review.


DNA damage enhancement from gold nanoparticles for clinical MV photon beams.

Berbeco RI, Korideck H, Ngwa W, Kumar R, Patel J, Sridhar S, Johnson S, Price BD, Kimmelman A, Makrigiorgos GM.

Radiat Res. 2012 Dec;178(6):604-8. doi: 10.1667/RR3001.1. Epub 2012 Nov 13.


Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair.

Xu Y, Ayrapetov MK, Xu C, Gursoy-Yuzugullu O, Hu Y, Price BD.

Mol Cell. 2012 Dec 14;48(5):723-33. doi: 10.1016/j.molcel.2012.09.026. Epub 2012 Oct 30.


The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1.

Xu C, Xu Y, Gursoy-Yuzugullu O, Price BD.

FEBS Lett. 2012 Nov 2;586(21):3920-5. doi: 10.1016/j.febslet.2012.09.030. Epub 2012 Sep 29.


Mechanistic links between ATM and histone methylation codes during DNA repair.

Xu Y, Xu C, Price BD.

Prog Mol Biol Transl Sci. 2012;110:263-88. doi: 10.1016/B978-0-12-387665-2.00010-9. Review.


The radioprotective agent WR1065 protects cells from radiation damage by regulating the activity of the Tip60 acetyltransferase.

Xu Y, Parmar K, Du F, Price BD, Sun Y.

Int J Biochem Mol Biol. 2011;2(4):295-302. Epub 2011 Oct 20.


Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity.

Ayrapetov MK, Xu C, Sun Y, Zhu K, Parmar K, D'Andrea AD, Price BD.

PLoS One. 2011;6(10):e26064. doi: 10.1371/journal.pone.0026064. Epub 2011 Oct 7.


Chromatin dynamics and the repair of DNA double strand breaks.

Xu Y, Price BD.

Cell Cycle. 2011 Jan 15;10(2):261-7. Epub 2011 Jan 15. Review.


Zyxin phosphorylation at serine 142 modulates the zyxin head-tail interaction to alter cell-cell adhesion.

Call GS, Chung JY, Davis JA, Price BD, Primavera TS, Thomson NC, Wagner MV, Hansen MD.

Biochem Biophys Res Commun. 2011 Jan 21;404(3):780-4. doi: 10.1016/j.bbrc.2010.12.058. Epub 2010 Dec 17.


Effects of high-oil corn on feedlot performance, carcass characteristics, fatty acid profiles, beef palatability, and retail case life traits of beef top loin steaks.

Price BD, Garmyn AJ, Derington HM, Galyean ML, Jackson SP, Smith SB, Miller MF.

J Anim Sci. 2011 Mar;89(3):809-16. doi: 10.2527/jas.2010-3187. Epub 2010 Nov 19.


Competitive enhancement of HGF-induced epithelial scattering by accessory growth factors.

Chung JY, Davis JA, Price BD, Staley DM, Wagner MV, Warner SL, Bearss DJ, Hansen MD.

Exp Cell Res. 2011 Feb 1;317(3):307-18. doi: 10.1016/j.yexcr.2010.11.002. Epub 2010 Nov 11.


The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair.

Xu Y, Sun Y, Jiang X, Ayrapetov MK, Moskwa P, Yang S, Weinstock DM, Price BD.

J Cell Biol. 2010 Oct 4;191(1):31-43. doi: 10.1083/jcb.201001160. Epub 2010 Sep 27.


Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment.

Weng D, Cunin MC, Song B, Price BD, Eller MS, Gilchrest BA, Calderwood SK, Gong J.

Breast Cancer Res. 2010;12(5):R71. doi: 10.1186/bcr2639. Epub 2010 Sep 16.


Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer.

Lin CI, Whang EE, Donner DB, Du J, Lorch J, He F, Jiang X, Price BD, Moore FD Jr, Ruan DT.

Mol Cancer Res. 2010 Sep;8(9):1217-26. doi: 10.1158/1541-7786.MCR-10-0162. Epub 2010 Aug 24.


Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway.

Jiang X, Xu Y, Price BD.

FEBS Lett. 2010 Jul 2;584(13):2926-30. doi: 10.1016/j.febslet.2010.05.017. Epub 2010 May 17.


Tip60: connecting chromatin to DNA damage signaling.

Sun Y, Jiang X, Price BD.

Cell Cycle. 2010 Mar 1;9(5):930-6. Epub 2010 Mar 11. Review.


An elastically compressible phantom material with mechanical and x-ray attenuation properties equivalent to breast tissue.

Price BD, Gibson AP, Tan LT, Royle GJ.

Phys Med Biol. 2010 Feb 21;55(4):1177-88. doi: 10.1088/0031-9155/55/4/018. Epub 2010 Jan 28.


Autophagy: a new target for advanced papillary thyroid cancer therapy.

Lin CI, Whang EE, Abramson MA, Jiang X, Price BD, Donner DB, Moore FD Jr, Ruan DT.

Surgery. 2009 Dec;146(6):1208-14. doi: 10.1016/j.surg.2009.09.019.


High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones.

Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH.

Clin Cancer Res. 2009 Dec 1;15(23):7238-45. doi: 10.1158/1078-0432.CCR-09-1964. Epub 2009 Nov 17.


Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer.

Lin CI, Whang EE, Donner DB, Jiang X, Price BD, Carothers AM, Delaine T, Leffler H, Nilsson UJ, Nose V, Moore FD Jr, Ruan DT.

Mol Cancer Res. 2009 Oct;7(10):1655-62. doi: 10.1158/1541-7786.MCR-09-0274. Epub 2009 Oct 13.


Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

Sun Y, Jiang X, Xu Y, Ayrapetov MK, Moreau LA, Whetstine JR, Price BD.

Nat Cell Biol. 2009 Nov;11(11):1376-82. doi: 10.1038/ncb1982. Epub 2009 Sep 27.


Assessing the validity of modulation transfer function evaluation techniques with application to small area and scanned digital detectors.

Price BD, Esbrand CJ, Olivo A, Gibson AP, Hebden JC, Speller RD, Royle GJ.

Rev Sci Instrum. 2008 Nov;79(11):113103. doi: 10.1063/1.3020696.


An electrically-activated dynamic tissue-equivalent phantom for assessment of diffuse optical imaging systems.

Hebden JC, Brunker J, Correia T, Price BD, Gibson AP, Everdell NL.

Phys Med Biol. 2008 Jan 21;53(2):329-37. doi: 10.1088/0031-9155/53/2/002. Epub 2007 Dec 28.


DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity.

Sun Y, Xu Y, Roy K, Price BD.

Mol Cell Biol. 2007 Dec;27(24):8502-9. Epub 2007 Oct 8.


Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells.

Fernandes ND, Sun Y, Price BD.

J Biol Chem. 2007 Jun 1;282(22):16577-84. Epub 2007 Apr 10.


A soft deformable tissue-equivalent phantom for diffuse optical tomography.

Hebden JC, Price BD, Gibson AP, Royle G.

Phys Med Biol. 2006 Nov 7;51(21):5581-90. Epub 2006 Oct 16.


Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation.

Sun Y, Jiang X, Chen S, Price BD.

FEBS Lett. 2006 Aug 7;580(18):4353-6. Epub 2006 Jul 10.


Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity.

Roy K, Wang L, Makrigiorgos GM, Price BD.

Biochem Biophys Res Commun. 2006 Jun 9;344(3):821-6. Epub 2006 Apr 19.


The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM.

Jiang X, Sun Y, Chen S, Roy K, Price BD.

J Biol Chem. 2006 Jun 9;281(23):15741-6. Epub 2006 Apr 9.


A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM.

Sun Y, Jiang X, Chen S, Fernandes N, Price BD.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13182-7. Epub 2005 Sep 2.


DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM.

Fernandes N, Sun Y, Chen S, Paul P, Shaw RJ, Cantley LC, Price BD.

J Biol Chem. 2005 Apr 15;280(15):15158-64. Epub 2005 Feb 15.


Stable siRNA-mediated silencing of ATM alters the transcriptional profile of HeLa cells.

Chen S, Wang G, Makrigiorgos GM, Price BD.

Biochem Biophys Res Commun. 2004 May 14;317(4):1037-44.


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