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Author Correction: Building a global alliance of biofoundries.

Hillson N, Caddick M, Cai Y, Carrasco JA, Chang MW, Curach NC, Bell DJ, Feuvre RL, Friedman DC, Fu X, Gold ND, Herrgård MJ, Holowko MB, Johnson JR, Johnson RA, Keasling JD, Kitney RI, Kondo A, Liu C, Martin VJJ, Menolascina F, Ogino C, Patron NJ, Pavan M, Poh CL, Pretorius IS, Rosser SJ, Scrutton NS, Storch M, Tekotte H, Travnik E, Vickers CE, Yew WS, Yuan Y, Zhao H, Freemont PS.

Nat Commun. 2019 Jul 11;10(1):3132. doi: 10.1038/s41467-019-10862-1.


Building a global alliance of biofoundries.

Hillson N, Caddick M, Cai Y, Carrasco JA, Chang MW, Curach NC, Bell DJ, Le Feuvre R, Friedman DC, Fu X, Gold ND, Herrgård MJ, Holowko MB, Johnson JR, Johnson RA, Keasling JD, Kitney RI, Kondo A, Liu C, Martin VJJ, Menolascina F, Ogino C, Patron NJ, Pavan M, Poh CL, Pretorius IS, Rosser SJ, Scrutton NS, Storch M, Tekotte H, Travnik E, Vickers CE, Yew WS, Yuan Y, Zhao H, Freemont PS.

Nat Commun. 2019 May 9;10(1):2040. doi: 10.1038/s41467-019-10079-2. No abstract available. Erratum in: Nat Commun. 2019 Jul 11;10(1):3132.


Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance.

Xu X, Williams TC, Divne C, Pretorius IS, Paulsen IT.

Biotechnol Biofuels. 2019 Apr 23;12:97. doi: 10.1186/s13068-019-1427-6. eCollection 2019.


Population sequencing reveals clonal diversity and ancestral inbreeding in the grapevine cultivar Chardonnay.

Roach MJ, Johnson DL, Bohlmann J, van Vuuren HJJ, Jones SJM, Pretorius IS, Schmidt SA, Borneman AR.

PLoS Genet. 2018 Nov 20;14(11):e1007807. doi: 10.1371/journal.pgen.1007807. eCollection 2018 Nov.


Systems-based approaches enable identification of gene targets which improve the flavour profile of low-ethanol wine yeast strains.

Varela C, Schmidt SA, Borneman AR, Pang CNI, Krömerx JO, Khan A, Song X, Hodson MP, Solomon M, Mayr CM, Hines W, Pretorius IS, Baker MS, Roessner U, Mercurio M, Henschke PA, Wilkins MR, Chambers PJ.

Metab Eng. 2018 Sep;49:178-191. doi: 10.1016/j.ymben.2018.08.006. Epub 2018 Aug 20.


Applications of Yeast Synthetic Biology Geared towards the Production of Biopharmaceuticals.

Walker RSK, Pretorius IS.

Genes (Basel). 2018 Jul 6;9(7). pii: E340. doi: 10.3390/genes9070340. Review.


Yeast 2.0-connecting the dots in the construction of the world's first functional synthetic eukaryotic genome.

Pretorius IS, Boeke JD.

FEMS Yeast Res. 2018 Jun 1;18(4). doi: 10.1093/femsyr/foy032. Review.


Solving yeast jigsaw puzzles over a glass of wine: Synthetic genome engineering pioneers new possibilities for wine yeast research.

Pretorius IS.

EMBO Rep. 2017 Nov;18(11):1875-1884. doi: 10.15252/embr.201745231. Epub 2017 Oct 23. No abstract available.


Synthetic biology stretching the realms of possibility in wine yeast research.

Jagtap UB, Jadhav JP, Bapat VA, Pretorius IS.

Int J Food Microbiol. 2017 Jul 3;252:24-34. doi: 10.1016/j.ijfoodmicro.2017.04.006. Epub 2017 Apr 20. Review.


Yeast's balancing act between ethanol and glycerol production in low-alcohol wines.

Goold HD, Kroukamp H, Williams TC, Paulsen IT, Varela C, Pretorius IS.

Microb Biotechnol. 2017 Mar;10(2):264-278. doi: 10.1111/1751-7915.12488. Epub 2017 Jan 13. Review.


Synthetic genome engineering forging new frontiers for wine yeast.

Pretorius IS.

Crit Rev Biotechnol. 2017 Feb;37(1):112-136. Epub 2016 Aug 18. Review.


Synthetic Evolution of Metabolic Productivity Using Biosensors.

Williams TC, Pretorius IS, Paulsen IT.

Trends Biotechnol. 2016 May;34(5):371-381. doi: 10.1016/j.tibtech.2016.02.002. Epub 2016 Mar 3. Review.


Heterologous production of raspberry ketone in the wine yeast Saccharomyces cerevisiae via pathway engineering and synthetic enzyme fusion.

Lee D, Lloyd ND, Pretorius IS, Borneman AR.

Microb Cell Fact. 2016 Mar 4;15:49. doi: 10.1186/s12934-016-0446-2.


Genomic insights into the Saccharomyces sensu stricto complex.

Borneman AR, Pretorius IS.

Genetics. 2015 Feb;199(2):281-91. doi: 10.1534/genetics.114.173633. Review.


Festive foods.

Pretorius IS.

FEMS Microbiol Lett. 2014 Nov;360(2):85-6. doi: 10.1111/1574-6968.12632. Epub 2014 Nov 10. No abstract available.


Genomic insights into the evolution of industrial yeast species Brettanomyces bruxellensis.

Curtin CD, Pretorius IS.

FEMS Yeast Res. 2014 Nov;14(7):997-1005. doi: 10.1111/1567-1364.12198. Epub 2014 Sep 15. Review.


Not your ordinary yeast: non-Saccharomyces yeasts in wine production uncovered.

Jolly NP, Varela C, Pretorius IS.

FEMS Yeast Res. 2014 Mar;14(2):215-37. doi: 10.1111/1567-1364.12111. Epub 2013 Nov 11. Review.


At the cutting-edge of grape and wine biotechnology.

Borneman AR, Schmidt SA, Pretorius IS.

Trends Genet. 2013 Apr;29(4):263-71. doi: 10.1016/j.tig.2012.10.014. Epub 2012 Dec 4. Review.


Novel wine yeast with mutations in YAP1 that produce less acetic acid during fermentation.

Cordente AG, Cordero-Bueso G, Pretorius IS, Curtin CD.

FEMS Yeast Res. 2013 Feb;13(1):62-73. doi: 10.1111/1567-1364.12010. Epub 2012 Nov 12.


Comparative genomics: a revolutionary tool for wine yeast strain development.

Borneman AR, Pretorius IS, Chambers PJ.

Curr Opin Biotechnol. 2013 Apr;24(2):192-9. doi: 10.1016/j.copbio.2012.08.006. Epub 2012 Sep 1. Review.


Flavour-active wine yeasts.

Cordente AG, Curtin CD, Varela C, Pretorius IS.

Appl Microbiol Biotechnol. 2012 Nov;96(3):601-18. doi: 10.1007/s00253-012-4370-z. Epub 2012 Sep 1. Review.


Evaluation of gene modification strategies for the development of low-alcohol-wine yeasts.

Varela C, Kutyna DR, Solomon MR, Black CA, Borneman A, Henschke PA, Pretorius IS, Chambers PJ.

Appl Environ Microbiol. 2012 Sep;78(17):6068-77. doi: 10.1128/AEM.01279-12. Epub 2012 Jun 22.


The winemaker's bug: From ancient wisdom to opening new vistas with frontier yeast science.

Pretorius IS, Curtin CD, Chambers PJ.

Bioeng Bugs. 2012 May-Jun;3(3):147-56. doi: 10.4161/bbug.19687. Epub 2012 May 1. Review.


De-novo assembly and analysis of the heterozygous triploid genome of the wine spoilage yeast Dekkera bruxellensis AWRI1499.

Curtin CD, Borneman AR, Chambers PJ, Pretorius IS.

PLoS One. 2012;7(3):e33840. doi: 10.1371/journal.pone.0033840. Epub 2012 Mar 28.


A breeding strategy to harness flavor diversity of Saccharomyces interspecific hybrids and minimize hydrogen sulfide production.

Bizaj E, Cordente AG, Bellon JR, Raspor P, Curtin CD, Pretorius IS.

FEMS Yeast Res. 2012 Jun;12(4):456-65. doi: 10.1111/j.1567-1364.2012.00797.x. Epub 2012 Apr 10.


The genome sequence of the wine yeast VIN7 reveals an allotriploid hybrid genome with Saccharomyces cerevisiae and Saccharomyces kudriavzevii origins.

Borneman AR, Desany BA, Riches D, Affourtit JP, Forgan AH, Pretorius IS, Egholm M, Chambers PJ.

FEMS Yeast Res. 2012 Feb;12(1):88-96. doi: 10.1111/j.1567-1364.2011.00773.x. Epub 2011 Dec 23.


Whole-genome comparison reveals novel genetic elements that characterize the genome of industrial strains of Saccharomyces cerevisiae.

Borneman AR, Desany BA, Riches D, Affourtit JP, Forgan AH, Pretorius IS, Egholm M, Chambers PJ.

PLoS Genet. 2011 Feb 3;7(2):e1001287. doi: 10.1371/journal.pgen.1001287.


Fermenting knowledge: the history of winemaking, science and yeast research.

Chambers PJ, Pretorius IS.

EMBO Rep. 2010 Dec;11(12):914-20. doi: 10.1038/embor.2010.179. Epub 2010 Nov 12. No abstract available.


Preliminary evaluation of infrared spectroscopy for the differentiation of Brettanomyces bruxellensis strains isolated from red wines.

Oelofse A, Malherbe S, Pretorius IS, Du Toit M.

Int J Food Microbiol. 2010 Oct 15;143(3):136-42. doi: 10.1016/j.ijfoodmicro.2010.08.004. Epub 2010 Aug 11.


Establishing a risk-assessment process for release of genetically modified wine yeast into the environment.

Schoeman H, Wolfaardt GM, Botha A, van Rensburg P, Pretorius IS.

Can J Microbiol. 2009 Aug;55(8):990-1002. doi: 10.1139/w09-039.


Isolation of sulfite reductase variants of a commercial wine yeast with significantly reduced hydrogen sulfide production.

Cordente AG, Heinrich A, Pretorius IS, Swiegers JH.

FEMS Yeast Res. 2009 May;9(3):446-59. doi: 10.1111/j.1567-1364.2009.00489.x. Epub 2009 Feb 19.


The influence of yeast on the aroma of Sauvignon Blanc wine.

Swiegers JH, Kievit RL, Siebert T, Lattey KA, Bramley BR, Francis IL, King ES, Pretorius IS.

Food Microbiol. 2009 Apr;26(2):204-11. doi: 10.1016/ Epub 2008 Nov 5.


Coinoculated fermentations using saccharomyces yeasts affect the volatile composition and sensory properties of Vitis vinifera L. cv. sauvignon blanc wines.

King ES, Swiegers JH, Travis B, Francis IL, Bastian SE, Pretorius IS.

J Agric Food Chem. 2008 Nov 26;56(22):10829-37. doi: 10.1021/jf801695h.


Comparative genome analysis of a Saccharomyces cerevisiae wine strain.

Borneman AR, Forgan AH, Pretorius IS, Chambers PJ.

FEMS Yeast Res. 2008 Nov;8(7):1185-95. doi: 10.1111/j.1567-1364.2008.00434.x. Epub 2008 Sep 4.


Controlled expression of the dominant flocculation genes FLO1, FLO5, and FLO11 in Saccharomyces cerevisiae.

Govender P, Domingo JL, Bester MC, Pretorius IS, Bauer FF.

Appl Environ Microbiol. 2008 Oct;74(19):6041-52. doi: 10.1128/AEM.00394-08. Epub 2008 Aug 15.


The Thr505 and Ser557 residues of the AGT1-encoded alpha-glucoside transporter are critical for maltotriose transport in Saccharomyces cerevisiae.

Smit A, Moses SG, Pretorius IS, Cordero Otero RR.

J Appl Microbiol. 2008 Apr;104(4):1103-11. doi: 10.1111/j.1365-2672.2007.03671.x. Epub 2007 Dec 20.


The heterologous expression of polysaccharidase-encoding genes with oenological relevance in Saccharomyces cerevisiae.

van Rensburg P, Strauss ML, Lambrechts MG, Cordero Otero RR, Pretorius IS.

J Appl Microbiol. 2007 Dec;103(6):2248-57.


Correlation between glucose/fructose discrepancy and hexokinase kinetic properties in different Saccharomyces cerevisiae wine yeast strains.

Berthels NJ, Cordero Otero RR, Bauer FF, Pretorius IS, Thevelein JM.

Appl Microbiol Biotechnol. 2008 Jan;77(5):1083-91. Epub 2007 Oct 23.


Influence of wine fermentation temperature on the synthesis of yeast-derived volatile aroma compounds.

Molina AM, Swiegers JH, Varela C, Pretorius IS, Agosin E.

Appl Microbiol Biotechnol. 2007 Dec;77(3):675-87. Epub 2007 Oct 16.


Assimilable nitrogen utilisation and production of volatile and non-volatile compounds in chemically defined medium by Saccharomyces cerevisiae wine yeasts.

Vilanova M, Ugliano M, Varela C, Siebert T, Pretorius IS, Henschke PA.

Appl Microbiol Biotechnol. 2007 Nov;77(1):145-57. Epub 2007 Sep 11.


Yeast systems biology: modelling the winemaker's art.

Borneman AR, Chambers PJ, Pretorius IS.

Trends Biotechnol. 2007 Aug;25(8):349-55. Epub 2007 Jun 27. Review.


Engineering volatile thiol release in Saccharomyces cerevisiae for improved wine aroma.

Swiegers JH, Capone DL, Pardon KH, Elsey GM, Sefton MA, Francis IL, Pretorius IS.

Yeast. 2007 Jul;24(7):561-74.


Effect of the cellulose-binding domain on the catalytic activity of a beta-glucosidase from Saccharomycopsis fibuligera.

Gundllapalli SB, Pretorius IS, Cordero Otero RR.

J Ind Microbiol Biotechnol. 2007 Jun;34(6):413-21. Epub 2007 Feb 27.


Modulation of volatile sulfur compounds by wine yeast.

Swiegers JH, Pretorius IS.

Appl Microbiol Biotechnol. 2007 Apr;74(5):954-60. Epub 2007 Jan 30. Review.


Modulating aroma compounds during wine fermentation by manipulating carnitine acetyltransferases in Saccharomyces cerevisiae.

Cordente AG, Swiegers JH, Hegardt FG, Pretorius IS.

FEMS Microbiol Lett. 2007 Feb;267(2):159-66. Epub 2006 Nov 29.


The grapevine polygalacturonase-inhibiting protein (VvPGIP1) reduces Botrytis cinerea susceptibility in transgenic tobacco and differentially inhibits fungal polygalacturonases.

Joubert DA, Slaughter AR, Kemp G, Becker JV, Krooshof GH, Bergmann C, Benen J, Pretorius IS, Vivier MA.

Transgenic Res. 2006 Dec;15(6):687-702. Epub 2006 Oct 27.


The effect of increased yeast alcohol acetyltransferase and esterase activity on the flavour profiles of wine and distillates.

Lilly M, Bauer FF, Lambrechts MG, Swiegers JH, Cozzolino D, Pretorius IS.

Yeast. 2006 Jul 15;23(9):641-59.


Regulation of respiratory growth by Ras: the glyoxylate cycle mutant, cit2Delta, is suppressed by RAS2.

Swiegers JH, Pretorius IS, Bauer FF.

Curr Genet. 2006 Sep;50(3):161-71. Epub 2006 Jul 11.


Rapid screening of the fermentation profiles of wine yeasts by Fourier transform infrared spectroscopy.

Nieuwoudt HH, Pretorius IS, Bauer FF, Nel DG, Prior BA.

J Microbiol Methods. 2006 Nov;67(2):248-56. Epub 2006 May 11.


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