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A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis.

Alt JA, Lee WY, Davis BM, Savage JR, Kennedy TP, Prestwich GD, Pulsipher A.

PLoS One. 2018 Sep 25;13(9):e0204709. doi: 10.1371/journal.pone.0204709. eCollection 2018.


Unusual subunits are directly involved in binding substrates for natural rubber biosynthesis in multiple plant species.

Cornish K, Scott DJ, Xie W, Mau CJD, Zheng YF, Liu XH, Prestwich GD.

Phytochemistry. 2018 Dec;156:55-72. doi: 10.1016/j.phytochem.2018.08.014. Epub 2018 Sep 5.


IL-33 mast cell axis is central in LL-37 induced bladder inflammation and pain in a murine interstitial cystitis model.

Martin Jensen M, Jia W, Schults AJ, Ye X, Prestwich GD, Oottamasathien S.

Cytokine. 2018 Oct;110:420-427. doi: 10.1016/j.cyto.2018.05.012. Epub 2018 May 18.


Bladder pain in an LL-37 interstitial cystitis and painful bladder syndrome model.

Jia W, Schults AJ, Jensen MM, Ye X, Alt JA, Prestwich GD, Oottamasathien S.

Am J Clin Exp Urol. 2017 Sep 1;5(2):10-17. eCollection 2017.


Silk-elastinlike protein polymers enhance the efficacy of a therapeutic glycosaminoglycan for prophylactic treatment of radiation-induced proctitis.

Jensen MM, Jia W, Isaacson KJ, Schults A, Cappello J, Prestwich GD, Oottamasathien S, Ghandehari H.

J Control Release. 2017 Oct 10;263:46-56. doi: 10.1016/j.jconrel.2017.02.025. Epub 2017 Feb 21.


The Life of Pi Star: Exploring the Exciting and Forbidden Worlds of the Benzophenone Photophore.

Dormán G, Nakamura H, Pulsipher A, Prestwich GD.

Chem Rev. 2016 Dec 28;116(24):15284-15398. doi: 10.1021/acs.chemrev.6b00342. Epub 2016 Dec 16. Review.


Prevention of sinonasal inflammation by a synthetic glycosaminoglycan.

Pulsipher A, Qin X, Thomas AJ, Prestwich GD, Oottamasathien S, Alt JA.

Int Forum Allergy Rhinol. 2017 Feb;7(2):177-184. doi: 10.1002/alr.21865. Epub 2016 Nov 11.


The Role of Neutrophil Proteins on the Amyloid Beta-RAGE Axis.

Stock AJ, Kasus-Jacobi A, Wren JD, Sjoelund VH, Prestwich GD, Pereira HA.

PLoS One. 2016 Sep 27;11(9):e0163330. doi: 10.1371/journal.pone.0163330. eCollection 2016.


TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye.

Ryskamp DA, Frye AM, Phuong TT, Yarishkin O, Jo AO, Xu Y, Lakk M, Iuso A, Redmon SN, Ambati B, Hageman G, Prestwich GD, Torrejon KY, Križaj D.

Sci Rep. 2016 Aug 11;6:30583. doi: 10.1038/srep30583.


A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis.

Savage JR, Pulsipher A, Rao NV, Kennedy TP, Prestwich GD, Ryan ME, Lee WY.

PLoS One. 2016 Jun 16;11(6):e0157310. doi: 10.1371/journal.pone.0157310. eCollection 2016.


Recent advances in hyaluronic acid hydrogels for biomedical applications.

Highley CB, Prestwich GD, Burdick JA.

Curr Opin Biotechnol. 2016 Aug;40:35-40. doi: 10.1016/j.copbio.2016.02.008. Epub 2016 Feb 27. Review.


Correction: Dual Action of Lysophosphatidate-Functionalised Titanium: Interactions with Human (MG63) Osteoblasts and Methicillin Resistant Staphylococcus aureus.

Skindersoe ME, Krogfelt KA, Blom A, Zhang J, Jiang G, Prestwich GD, Mansell JP.

PLoS One. 2016 Jan 21;11(1):e0147276. doi: 10.1371/journal.pone.0147276. eCollection 2016. No abstract available.


Dual Action of Lysophosphatidate-Functionalised Titanium: Interactions with Human (MG63) Osteoblasts and Methicillin Resistant Staphylococcus aureus.

Skindersoe ME, Krogfelt KA, Blom A, Zhang J, Jiang G, Prestwich GD, Mansell JP.

PLoS One. 2015 Nov 25;10(11):e0143509. doi: 10.1371/journal.pone.0143509. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0147276. Zhang, Jianxing [added].


Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery.

Woodman JL, Suh MS, Zhang J, Kondaveeti Y, Burgess DJ, White BA, Prestwich GD, Kuhn LT.

Int J Cell Biol. 2015;2015:249573. doi: 10.1155/2015/249573. Epub 2015 Sep 10.


Topical cathelicidin (LL-37) an innate immune peptide induces acute olfactory epithelium inflammation in a mouse model.

Alt JA, Qin X, Pulsipher A, Orb Q, Orlandi RR, Zhang J, Schults A, Jia W, Presson AP, Prestwich GD, Oottamasathien S.

Int Forum Allergy Rhinol. 2015 Dec;5(12):1141-50. doi: 10.1002/alr.21634. Epub 2015 Sep 8.


Autotaxin and Endotoxin-Induced Acute Lung Injury.

Mouratis MA, Magkrioti C, Oikonomou N, Katsifa A, Prestwich GD, Kaffe E, Aidinis V.

PLoS One. 2015 Jul 21;10(7):e0133619. doi: 10.1371/journal.pone.0133619. eCollection 2015.


Vinyl sulfone analogs of lysophosphatidylcholine irreversibly inhibit autotaxin and prevent angiogenesis in melanoma.

Murph MM, Jiang GW, Altman MK, Jia W, Nguyen DT, Fambrough JM, Hardman WJ, Nguyen HT, Tran SK, Alshamrani AA, Madan D, Zhang J, Prestwich GD.

Bioorg Med Chem. 2015 Sep 1;23(17):5999-6013. doi: 10.1016/j.bmc.2015.06.054. Epub 2015 Jul 2.


'Erratum to "Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines" [Biomaterials 33 (2012) 4712-4721]'.

Astashkina AI, Mann BK, Prestwich GD, Grainger DW.

Biomaterials. 2015 Jan;38:108. doi: 10.1016/j.biomaterials.2014.10.072. Epub 2014 Nov 11. No abstract available.


Why regenerative medicine needs an extracellular matrix.

Prestwich GD, Healy KE.

Expert Opin Biol Ther. 2015 Jan;15(1):3-7. doi: 10.1517/14712598.2015.975200.


Ophthalmic Uses of a Thiol-Modified Hyaluronan-Based Hydrogel.

Wirostko B, Mann BK, Williams DL, Prestwich GD.

Adv Wound Care (New Rochelle). 2014 Nov 1;3(11):708-716. Review.


Targeting Glutathione S-transferase M4 in Ewing sarcoma.

Zhuo R, Kosak KM, Sankar S, Wiles ET, Sun Y, Zhang J, Ayello J, Prestwich GD, Shami PJ, Cairo MS, Lessnick SL, Luo W.

Front Pediatr. 2014 Aug 6;2:83. doi: 10.3389/fped.2014.00083. eCollection 2014.


LL-37 induced cystitis and the receptor for advanced glycation end-products (RAGE) pathway.

Roundy LM, Jia W, Zhang J, Ye X, Prestwich GD, Oottamasathien S.

Adv Biosci Biotechnol. 2013 Aug 1;4(8B):1-8.


Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate.

Madan D, Ferguson CG, Lee WY, Prestwich GD, Testa CA.

PLoS One. 2013 Nov 20;8(11):e79065. doi: 10.1371/journal.pone.0079065. eCollection 2013.


Prevention of anti-microbial peptide LL-37-induced apoptosis and ATP release in the urinary bladder by a modified glycosaminoglycan.

Lee WY, Savage JR, Zhang J, Jia W, Oottamasathien S, Prestwich GD.

PLoS One. 2013 Oct 30;8(10):e77854. doi: 10.1371/journal.pone.0077854. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/0b7d0567-2fbd-4d32-84f1-9a0a9c290e70.


Augmentation of integrin-mediated mechanotransduction by hyaluronic acid.

Chopra A, Murray ME, Byfield FJ, Mendez MG, Halleluyan R, Restle DJ, Raz-Ben Aroush D, Galie PA, Pogoda K, Bucki R, Marcinkiewicz C, Prestwich GD, Zarembinski TI, Chen CS, Puré E, Kresh JY, Janmey PA.

Biomaterials. 2014 Jan;35(1):71-82. doi: 10.1016/j.biomaterials.2013.09.066. Epub 2013 Oct 10.


Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation.

Park GY, Lee YG, Berdyshev E, Nyenhuis S, Du J, Fu P, Gorshkova IA, Li Y, Chung S, Karpurapu M, Deng J, Ranjan R, Xiao L, Jaffe HA, Corbridge SJ, Kelly EA, Jarjour NN, Chun J, Prestwich GD, Kaffe E, Ninou I, Aidinis V, Morris AJ, Smyth SS, Ackerman SJ, Natarajan V, Christman JW.

Am J Respir Crit Care Med. 2013 Oct 15;188(8):928-40. doi: 10.1164/rccm.201306-1014OC.


Exploiting differential surface display of chondroitin sulfate variants for directing neuronal outgrowth.

Swarup VP, Hsiao TW, Zhang J, Prestwich GD, Kuberan B, Hlady V.

J Am Chem Soc. 2013 Sep 11;135(36):13488-94. doi: 10.1021/ja4056728. Epub 2013 Aug 30.


A metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritis.

Nikitopoulou I, Kaffe E, Sevastou I, Sirioti I, Samiotaki M, Madan D, Prestwich GD, Aidinis V.

PLoS One. 2013 Jul 29;8(7):e70941. doi: 10.1371/journal.pone.0070941. Print 2013.


The influence of collagen and hyaluronan matrices on the delivery and bioactivity of bone morphogenetic protein-2 and ectopic bone formation.

Bhakta G, Lim ZX, Rai B, Lin T, Hui JH, Prestwich GD, van Wijnen AJ, Nurcombe V, Cool SM.

Acta Biomater. 2013 Nov;9(11):9098-106. doi: 10.1016/j.actbio.2013.07.008. Epub 2013 Jul 19.


Delivery, retention and engraftment of progenitor cells in cell therapy.

Prestwich GD.

Biomatter. 2013 Jan-Mar;3(1). pii: e24549. doi: 10.4161/biom.24549. Epub 2013 Jan 1. No abstract available.


Cross-linked hydrogel and polyester resorbable ventilation tubes in a Chinchilla model.

Park AH, Hoyt D, Britt D, Chase S, Tansavatdi K, Hunter L, McGill L, Sheng X, Skardal A, Prestwich GD.

Laryngoscope. 2013 Apr;123(4):1043-8. doi: 10.1002/lary.23712. Epub 2013 Mar 19.


Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA): metabolically stabilized LPA receptor agonists.

Jiang G, Inoue A, Aoki J, Prestwich GD.

Bioorg Med Chem Lett. 2013 Mar 15;23(6):1865-9. doi: 10.1016/j.bmcl.2013.01.002. Epub 2013 Jan 23.


Culture of impact: faculty as mentors for student entrepreneurs.

Prestwich GD.

Sci Transl Med. 2013 Jan 23;5(169):169ed2. doi: 10.1126/scitranslmed.3004488. No abstract available.


Physiological relevance of LL-37 induced bladder inflammation and mast cells.

Oottamasathien S, Jia W, Roundy LM, Zhang J, Wang L, Ye X, Hill AC, Savage J, Lee WY, Hannon AM, Milner S, Prestwich GD.

J Urol. 2013 Oct;190(4 Suppl):1596-1602. doi: 10.1016/j.juro.2013.01.002. Epub 2013 Jan 9.


What is the greatest regulatory challenge in the translation of biomaterials to the clinic?

Prestwich GD, Bhatia S, Breuer CK, Dahl SL, Mason C, McFarland R, McQuillan DJ, Sackner-Bernstein J, Schox J, Tente WE, Trounson A.

Sci Transl Med. 2012 Nov 14;4(160):160cm14. doi: 10.1126/scitranslmed.3004915.


The translational imperative: making cell therapy simple and effective.

Prestwich GD, Erickson IE, Zarembinski TI, West M, Tew WP.

Acta Biomater. 2012 Dec;8(12):4200-7. doi: 10.1016/j.actbio.2012.06.043. Epub 2012 Jul 7. Review.


Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis.

Oikonomou N, Mouratis MA, Tzouvelekis A, Kaffe E, Valavanis C, Vilaras G, Karameris A, Prestwich GD, Bouros D, Aidinis V.

Am J Respir Cell Mol Biol. 2012 Nov;47(5):566-74. doi: 10.1165/rcmb.2012-0004OC. Epub 2012 Jun 28.


Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2.

Bhakta G, Rai B, Lim ZX, Hui JH, Stein GS, van Wijnen AJ, Nurcombe V, Prestwich GD, Cool SM.

Biomaterials. 2012 Sep;33(26):6113-22. doi: 10.1016/j.biomaterials.2012.05.030. Epub 2012 Jun 9.


Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel.

Cheng K, Blusztajn A, Shen D, Li TS, Sun B, Galang G, Zarembinski TI, Prestwich GD, Marbán E, Smith RR, Marbán L.

Biomaterials. 2012 Jul;33(21):5317-24. doi: 10.1016/j.biomaterials.2012.04.006. Epub 2012 May 3.


Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines.

Astashkina AI, Mann BK, Prestwich GD, Grainger DW.

Biomaterials. 2012 Jun;33(18):4712-21. doi: 10.1016/j.biomaterials.2012.03.001. Epub 2012 Apr 2. Erratum in: Biomaterials. 2015 Jan;38:108.


Therapeutic potential of gel-based injectables for vocal fold regeneration.

Bartlett RS, Thibeault SL, Prestwich GD.

Biomed Mater. 2012 Apr;7(2):024103. doi: 10.1088/1748-6041/7/2/024103. Epub 2012 Mar 29.


A 3-D organoid kidney culture model engineered for high-throughput nephrotoxicity assays.

Astashkina AI, Mann BK, Prestwich GD, Grainger DW.

Biomaterials. 2012 Jun;33(18):4700-11. doi: 10.1016/j.biomaterials.2012.02.063. Epub 2012 Mar 22.


Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors.

Chopra A, Lin V, McCollough A, Atzet S, Prestwich GD, Wechsler AS, Murray ME, Oake SA, Kresh JY, Janmey PA.

J Biomech. 2012 Mar 15;45(5):824-31. doi: 10.1016/j.jbiomech.2011.11.023. Epub 2011 Dec 24.


Silk-hyaluronan-based composite hydrogels: a novel, securable vehicle for drug delivery.

Elia R, Newhide DR, Pedevillano PD, Reiss GR, Firpo MA, Hsu EW, Kaplan DL, Prestwich GD, Peattie RA.

J Biomater Appl. 2013 Feb;27(6):749-62. doi: 10.1177/0885328211424516. Epub 2011 Nov 15.


Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications.

He J, Gajewiak J, Scott JL, Gong D, Ali M, Best MD, Prestwich GD, Stahelin RV, Kutateladze TG.

Chem Biol. 2011 Oct 28;18(10):1312-9. doi: 10.1016/j.chembiol.2011.07.022.


LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling.

Inoue A, Arima N, Ishiguro J, Prestwich GD, Arai H, Aoki J.

EMBO J. 2011 Aug 19;30(20):4248-60. doi: 10.1038/emboj.2011.296.


A murine model of inflammatory bladder disease: cathelicidin peptide induced bladder inflammation and treatment with sulfated polysaccharides.

Oottamasathien S, Jia W, McCoard L, Slack S, Zhang J, Skardal A, Job K, Kennedy TP, Dull RO, Prestwich GD.

J Urol. 2011 Oct;186(4 Suppl):1684-92. doi: 10.1016/j.juro.2011.03.099. Epub 2011 Aug 19. Erratum in: J Urol. 2012 Feb;187(2):768.


The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (epsilon-caprolactone)/collagen fibers and hyaluronic acid hydrogel.

Ekaputra AK, Prestwich GD, Cool SM, Hutmacher DW.

Biomaterials. 2011 Nov;32(32):8108-17. doi: 10.1016/j.biomaterials.2011.07.022. Epub 2011 Jul 31.


Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche.

Lozoya OA, Wauthier E, Turner RA, Barbier C, Prestwich GD, Guilak F, Superfine R, Lubkin SR, Reid LM.

Biomaterials. 2011 Oct;32(30):7389-402. doi: 10.1016/j.biomaterials.2011.06.042. Epub 2011 Jul 23.


Bis (monoacylglycero) phosphate interfacial properties and lipolysis by pancreatic lipase-related protein 2, an enzyme present in THP-1 human monocytes.

Record M, Amara S, Subra C, Jiang G, Prestwich GD, Ferrato F, Carrière F.

Biochim Biophys Acta. 2011 Jul-Aug;1811(7-8):419-30. doi: 10.1016/j.bbalip.2011.04.008. Epub 2011 Apr 30.


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