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Items: 30


Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis.

Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold KC; Immune Tolerance Network.

Diabetologia. 2019 Apr;62(4):655-664. doi: 10.1007/s00125-018-4786-9. Epub 2018 Dec 19.


Identification and Analysis of Islet Antigen-Specific CD8+ T Cells with T Cell Libraries.

Ogura H, Preston-Hurlburt P, Perdigoto AL, Amodio M, Krishnaswamy S, Clark P, Yu H, Egli D, Fouts A, Steck AK, Herold KC.

J Immunol. 2018 Sep 15;201(6):1662-1670. doi: 10.4049/jimmunol.1800267. Epub 2018 Aug 6.


Microbiota control immune regulation in humanized mice.

Gülden E, Vudattu NK, Deng S, Preston-Hurlburt P, Mamula M, Reed JC, Mohandas S, Herold BC, Torres R, Vieira SM, Lim B, Herazo-Maya JD, Kriegel M, Goodman AL, Cotsapas C, Herold KC.

JCI Insight. 2017 Nov 2;2(21). pii: 91709. doi: 10.1172/jci.insight.91709.


Oral treatment with foralumab, a fully human anti-CD3 monoclonal antibody, prevents skin xenograft rejection in humanized mice.

Ogura M, Deng S, Preston-Hurlburt P, Ogura H, Shailubhai K, Kuhn C, Weiner HL, Herold KC.

Clin Immunol. 2017 Oct;183:240-246. doi: 10.1016/j.clim.2017.07.005. Epub 2017 Jul 21.


Role of Interleukin 32 in Human Immunodeficiency Virus Reactivation and Its Link to Human Immunodeficiency Virus-Herpes Simplex Virus Coinfection.

Mesquita PMM, Preston-Hurlburt P, Keller MJ, Vudattu N, Espinoza L, Altrich M, Anastos K, Herold KC, Herold BC.

J Infect Dis. 2017 Feb 15;215(4):614-622. doi: 10.1093/infdis/jiw612.


The Receptor for Advanced Glycation Endproducts Drives T Cell Survival and Inflammation in Type 1 Diabetes Mellitus.

Durning SP, Preston-Hurlburt P, Clark PR, Xu D, Herold KC; Type 1 Diabetes TrialNet Study Group.

J Immunol. 2016 Oct 15;197(8):3076-3085. Epub 2016 Sep 21.


Pillars Article: Sequence Analysis of Peptides Bound to MHC Class II Molecules. Nature. 1991. 353: 622-627.

Rudensky AY, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA Jr.

J Immunol. 2016 Feb 1;196(3):941-6. No abstract available.


Humanized mice as a model for aberrant responses in human T cell immunotherapy.

Vudattu NK, Waldron-Lynch F, Truman LA, Deng S, Preston-Hurlburt P, Torres R, Raycroft MT, Mamula MJ, Herold KC.

J Immunol. 2014 Jul 15;193(2):587-96. doi: 10.4049/jimmunol.1302455. Epub 2014 Jun 18.


The receptor for advanced glycation end products (RAGE) affects T cell differentiation in OVA induced asthma.

Akirav EM, Henegariu O, Preston-Hurlburt P, Schmidt AM, Clynes R, Herold KC.

PLoS One. 2014 Apr 23;9(4):e95678. doi: 10.1371/journal.pone.0095678. eCollection 2014.


Specific peripheral B cell tolerance defects in patients with multiple sclerosis.

Kinnunen T, Chamberlain N, Morbach H, Cantaert T, Lynch M, Preston-Hurlburt P, Herold KC, Hafler DA, O'Connor KC, Meffre E.

J Clin Invest. 2013 Jun;123(6):2737-41. doi: 10.1172/JCI68775. Epub 2013 May 15.


Relapsing and remitting severe hypoglycemia due to a monoclonal anti-insulin antibody heralding a case of multiple myeloma.

Waldron-Lynch F, Inzucchi SE, Menard L, Tai N, Preston-Hurlburt P, Hui P, McClaskey J, Hagopian WA, Meffre E, Marks PW, Wen L, Herold KC.

J Clin Endocrinol Metab. 2012 Dec;97(12):4317-23. doi: 10.1210/jc.2012-2388. Epub 2012 Oct 16.


Analysis of human biologics with a mouse skin transplant model in humanized mice.

Waldron-Lynch F, Deng S, Preston-Hurlburt P, Henegariu O, Herold KC.

Am J Transplant. 2012 Oct;12(10):2652-62. doi: 10.1111/j.1600-6143.2012.04178.x. Epub 2012 Aug 17.


Enhanced anti-serpin antibody activity inhibits autoimmune inflammation in type 1 diabetes.

Czyzyk J, Henegariu O, Preston-Hurlburt P, Baldzizhar R, Fedorchuk C, Esplugues E, Bottomly K, Gorus FK, Herold K, Flavell RA.

J Immunol. 2012 Jun 15;188(12):6319-27. doi: 10.4049/jimmunol.1200467. Epub 2012 May 16.


RAGE expression in human T cells: a link between environmental factors and adaptive immune responses.

Akirav EM, Preston-Hurlburt P, Garyu J, Henegariu O, Clynes R, Schmidt AM, Herold KC.

PLoS One. 2012;7(4):e34698. doi: 10.1371/journal.pone.0034698. Epub 2012 Apr 11.


Teplizumab induces human gut-tropic regulatory cells in humanized mice and patients.

Waldron-Lynch F, Henegariu O, Deng S, Preston-Hurlburt P, Tooley J, Flavell R, Herold KC.

Sci Transl Med. 2012 Jan 25;4(118):118ra12. doi: 10.1126/scitranslmed.3003401.


Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation.

Ablamunits V, Henegariu O, Hansen JB, Opare-Addo L, Preston-Hurlburt P, Santamaria P, Mandrup-Poulsen T, Herold KC.

Diabetes. 2012 Jan;61(1):145-54. doi: 10.2337/db11-1033. Epub 2011 Oct 31.


NKG2A is a marker for acquisition of regulatory function by human CD8+ T cells activated with anti-CD3 antibody.

Ablamunits V, Henegariu O, Preston-Hurlburt P, Herold KC.

Eur J Immunol. 2011 Jul;41(7):1832-42. doi: 10.1002/eji.201041258. Epub 2011 Jun 6.


T(H)17 cells mediate pulmonary collateral priming.

Albrecht M, Chen HC, Preston-Hurlburt P, Ranney P, Hoymann HG, Maxeiner J, Staudt V, Taube C, Bottomly HK, Dittrich AM.

J Allergy Clin Immunol. 2011 Jul;128(1):168-177.e8. doi: 10.1016/j.jaci.2011.01.067. Epub 2011 Apr 2.


Induction of TLR4-target genes entails calcium/calmodulin-dependent regulation of chromatin remodeling.

Lai D, Wan M, Wu J, Preston-Hurlburt P, Kushwaha R, Grundström T, Imbalzano AN, Chi T.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1169-74. doi: 10.1073/pnas.0811274106. Epub 2009 Jan 21.


A novel genetic strategy reveals unexpected roles of the Swi-Snf-like chromatin-remodeling BAF complex in thymocyte development.

Jani A, Wan M, Zhang J, Cui K, Wu J, Preston-Hurlburt P, Khatri R, Zhao K, Chi T.

J Exp Med. 2008 Nov 24;205(12):2813-25. doi: 10.1084/jem.20080938. Epub 2008 Oct 27.


Activation of CD4 T cells by Raf-independent effectors of Ras.

Czyzyk J, Brogdon JL, Badou A, Henegariu O, Preston Hurlburt P, Flavell R, Bottomly K.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):6003-8. Epub 2003 Apr 29.


Dual receptor T cells extend the immune repertoire for foreign antigens.

He X, Janeway CA Jr, Levine M, Robinson E, Preston-Hurlburt P, Viret C, Bottomly K.

Nat Immunol. 2002 Feb;3(2):127-34. Epub 2002 Jan 7.


MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

Medzhitov R, Preston-Hurlburt P, Kopp E, Stadlen A, Chen C, Ghosh S, Janeway CA Jr.

Mol Cell. 1998 Aug;2(2):253-8.


A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.

Medzhitov R, Preston-Hurlburt P, Janeway CA Jr.

Nature. 1997 Jul 24;388(6640):394-7.


The specificity and orientation of a TCR to its peptide-MHC class II ligands.

Sant'Angelo DB, Waterbury G, Preston-Hurlburt P, Yoon ST, Medzhitov R, Hong SC, Janeway CA Jr.

Immunity. 1996 Apr;4(4):367-76.


Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs.

Rudensky AYu, Preston-Hurlburt P, al-Ramadi BK, Rothbard J, Janeway CA Jr.

Nature. 1992 Oct 1;359(6394):429-31.


On the complexity of self.

Rudensky AYu, Rath S, Preston-Hurlburt P, Murphy DB, Janeway CA Jr.

Nature. 1991 Oct 17;353(6345):660-2.


Sequence analysis of peptides bound to MHC class II molecules.

Rudensky AYu, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA Jr.

Nature. 1991 Oct 17;353(6345):622-7.


The role of tyrosine at the ligand-binding site of the nicotinic acetylcholine receptor.

Pearce SF, Preston-Hurlburt P, Hawrot E.

Proc Biol Sci. 1990 Sep 22;241(1302):207-13.


Monoclonal antibodies directed against a synthetic peptide corresponding to the alpha-bungarotoxin binding region of the acetylcholine receptor.

Preston-Hurlburt P, Wilson PT, Dowding AJ, Hawrot E.

Biochim Biophys Acta. 1990 Mar 26;1033(3):324-8.


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