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Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG.

Iyer S, Sam FS, DiPrimio N, Preston G, Verheijen J, Murthy K, Parton Z, Tsang H, Lao J, Morava E, Perlstein EO.

Dis Model Mech. 2019 Nov 11;12(11). pii: dmm040584. doi: 10.1242/dmm.040584.


Moorfields AMD database report 2: fellow eye involvement with neovascular age-related macular degeneration.

Fasler K, Fu DJ, Moraes G, Wagner S, Gokhale E, Kortuem K, Chopra R, Faes L, Preston G, Pontikos N, Patel PJ, Tufail A, Lee AY, Balaskas K, Keane PA.

Br J Ophthalmol. 2019 Oct 14. pii: bjophthalmol-2019-314446. doi: 10.1136/bjophthalmol-2019-314446. [Epub ahead of print]


Relationships between airborne pollutants, serum albumin adducts and short-term health outcomes in an experimental crossover study.

Preston GW, Dagnino S, Ponzi E, Sozeri O, van Veldhoven K, Barratt B, Liu S, Grigoryan H, Lu SS, Rappaport SM, Chung KF, Cullinan P, Sinharay R, Kelly FJ, Chadeau-Hyam M, Vineis P, Phillips DH.

Chemosphere. 2020 Jan;239:124667. doi: 10.1016/j.chemosphere.2019.124667. Epub 2019 Aug 24.


Growing edible mushrooms: a conversation between bacteria and fungi.

Carrasco J, Preston GM.

Environ Microbiol. 2020 Mar;22(3):858-872. doi: 10.1111/1462-2920.14765. Epub 2019 Sep 9. Review.


Diagnosis and Management Strategies for Distal Biceps Rupture.

Holt J, Preston G, Heindel K, Preston H, Hill G.

Orthopedics. 2019 Nov 1;42(6):e492-e501. doi: 10.3928/01477447-20190723-05. Epub 2019 Jul 29. Review.


One- and two-year visual outcomes from the Moorfields age-related macular degeneration database: a retrospective cohort study and an open science resource.

Fasler K, Moraes G, Wagner S, Kortuem KU, Chopra R, Faes L, Preston G, Pontikos N, Fu DJ, Patel P, Tufail A, Lee AY, Balaskas K, Keane PA.

BMJ Open. 2019 Jun 21;9(6):e027441. doi: 10.1136/bmjopen-2018-027441.


Protein Adductomics: Analytical Developments and Applications in Human Biomonitoring.

Preston GW, Phillips DH.

Toxics. 2019 May 25;7(2). pii: E29. doi: 10.3390/toxics7020029. Review.


Exploring the Functional Consequences of Protein Backbone Alteration in Ubiquitin through Native Chemical Ligation.

Werner HM, Estabrooks SK, Preston GM, Brodsky JL, Horne WS.

Chembiochem. 2019 Sep 16;20(18):2346-2350. doi: 10.1002/cbic.201900225. Epub 2019 Aug 23.


Hsp104 facilitates the endoplasmic-reticulum-associated degradation of disease-associated and aggregation-prone substrates.

Doonan LM, Guerriero CJ, Preston GM, Buck TM, Khazanov N, Fisher EA, Senderowitz H, Brodsky JL.

Protein Sci. 2019 Jul;28(7):1290-1306. doi: 10.1002/pro.3636. Epub 2019 May 20.


Casing microbiome dynamics during button mushroom cultivation: implications for dry and wet bubble diseases.

Carrasco J, Tello ML, de Toro M, Tkacz A, Poole P, Pérez-Clavijo M, Preston G.

Microbiology. 2019 Jun;165(6):611-624. doi: 10.1099/mic.0.000792. Epub 2019 Apr 17.


Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides.

Buscaill P, Chandrasekar B, Sanguankiattichai N, Kourelis J, Kaschani F, Thomas EL, Morimoto K, Kaiser M, Preston GM, Ichinose Y, van der Hoorn RAL.

Science. 2019 Apr 12;364(6436). pii: eaav0748. doi: 10.1126/science.aav0748.


Variation in defence strategies in the metal hyperaccumulator plant Noccaea caerulescens is indicative of synergies and trade-offs between forms of defence.

Fones HN, Preston GM, Smith JAC.

R Soc Open Sci. 2019 Jan 23;6(1):172418. doi: 10.1098/rsos.172418. eCollection 2019 Jan.


Chronic Morbidity of a Pilot Hole Burr Technique for Anterior Iliac Crest Autograft in Cervical Fusion.

Heindel KJ, Preston GP, Tharp JS.

Orthopedics. 2019 Jan 1;42(1):e68-e73. doi: 10.3928/01477447-20181120-02. Epub 2018 Nov 28.


Pseudomonas syringae: enterprising epiphyte and stealthy parasite.

Arnold DL, Preston GM.

Microbiology. 2019 Mar;165(3):251-253. doi: 10.1099/mic.0.000715. Epub 2018 Nov 14.


Supplementation in mushroom crops and its impact on yield and quality.

Carrasco J, Zied DC, Pardo JE, Preston GM, Pardo-Giménez A.

AMB Express. 2018 Sep 18;8(1):146. doi: 10.1186/s13568-018-0678-0. Review.


Supercoiling of an excised genomic island represses effector gene expression to prevent activation of host resistance.

Neale HC, Jackson RW, Preston GM, Arnold DL.

Mol Microbiol. 2018 Nov;110(3):444-454. doi: 10.1111/mmi.14111. Epub 2018 Oct 3.


Drug induced thrombotic microangiopathy caused by levofloxacin.

Kazi S, Preston GC.

J R Coll Physicians Edinb. 2018 Jun;48(2):127-129. doi: 10.4997/JRCPE.2018.206.


Substrate Insolubility Dictates Hsp104-Dependent Endoplasmic-Reticulum-Associated Degradation.

Preston GM, Guerriero CJ, Metzger MB, Michaelis S, Brodsky JL.

Mol Cell. 2018 Apr 19;70(2):242-253.e6. doi: 10.1016/j.molcel.2018.03.016.


The role of suboptimal mitochondrial function in vulnerability to post-traumatic stress disorder.

Preston G, Kirdar F, Kozicz T.

J Inherit Metab Dis. 2018 Jul;41(4):585-596. doi: 10.1007/s10545-018-0168-1. Epub 2018 Mar 28. Review.


Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo.

Dickinson RS, Murphy F, Doherty C, Williams S, Mirchandani A, Willson J, Scotti JS, Preston G, Schofield CJ, Whyte MKB, Walmsley SR.

Wellcome Open Res. 2017 Oct 26;2:104. doi: 10.12688/wellcomeopenres.12871.1. eCollection 2017.


Methods to Quantify Biotic-Induced Stress in Plants.

Bach-Pages M, Preston GM.

Methods Mol Biol. 2018;1734:241-255. doi: 10.1007/978-1-4939-7604-1_19.


Expanding the phenotype of metabolic cutis laxa with an additional disorder of N-linked protein glycosylation.

Witters P, Breckpot J, Foulquier F, Preston G, Jaeken J, Morava E.

Eur J Hum Genet. 2018 May;26(5):618-621. doi: 10.1038/s41431-017-0044-8. Epub 2017 Nov 30. No abstract available.


Association of Osteopontin, Neopterin, and Myeloperoxidase With Stroke Risk in Patients With Prior Stroke or Transient Ischemic Attacks: Results of an Analysis of 13 Biomarkers From the Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trial.

Ganz P, Amarenco P, Goldstein LB, Sillesen H, Bao W, Preston GM, Welch KMA; SPARCL Steering Committee.

Stroke. 2017 Dec;48(12):3223-3231. doi: 10.1161/STROKEAHA.117.017965. Epub 2017 Nov 7.


Refinement of a Methodology for Untargeted Detection of Serum Albumin Adducts in Human Populations.

Preston GW, Plusquin M, Sozeri O, van Veldhoven K, Bastian L, Nawrot TS, Chadeau-Hyam M, Phillips DH.

Chem Res Toxicol. 2017 Dec 18;30(12):2120-2129. doi: 10.1021/acs.chemrestox.7b00186. Epub 2017 Nov 17.


Measurement of Oxygen Status in Arabidopsis Leaves Undergoing the Hypersensitive Response During Pseudomonas Infection.

Kumari A, Preston GM, Gupta KJ.

Methods Mol Biol. 2017;1670:71-76. doi: 10.1007/978-1-4939-7292-0_8.


T2 vertebrectomy with combined anterior and posterior arthrodesis for treatment of a solitary plasmacytoma.

Preston G, Anton T.

Surg Neurol Int. 2017 Aug 9;8:173. doi: 10.4103/sni.sni_209_17. eCollection 2017.


Targeting Anti-TGF-β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach.

McGaraughty S, Davis-Taber RA, Zhu CZ, Cole TB, Nikkel AL, Chhaya M, Doyle KJ, Olson LM, Preston GM, Grinnell CM, Salte KM, Giamis AM, Luo Y, Sun V, Goodearl AD, Gopalakrishnan M, Lacy SE.

J Am Soc Nephrol. 2017 Dec;28(12):3616-3626. doi: 10.1681/ASN.2017010013. Epub 2017 Aug 21.


Development of SimCells as a novel chassis for functional biosensors.

Rampley CPN, Davison PA, Qian P, Preston GM, Hunter CN, Thompson IP, Wu LJ, Huang WE.

Sci Rep. 2017 Aug 3;7(1):7261. doi: 10.1038/s41598-017-07391-6.


Oral D-galactose supplementation in PGM1-CDG.

Wong SY, Gadomski T, van Scherpenzeel M, Honzik T, Hansikova H, Holmefjord KSB, Mork M, Bowling F, Sykut-Cegielska J, Koch D, Hertecant J, Preston G, Jaeken J, Peeters N, Perez S, Nguyen DD, Crivelly K, Emmerzaal T, Gibson KM, Raymond K, Abu Bakar N, Foulquier F, Poschet G, Ackermann AM, He M, Lefeber DJ, Thiel C, Kozicz T, Morava E.

Genet Med. 2017 Nov;19(11):1226-1235. doi: 10.1038/gim.2017.41. Epub 2017 Jun 15.


Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates.

Guerriero CJ, Reutter KR, Augustine AA, Preston GM, Weiberth KF, Mackie TD, Cleveland-Rubeor HC, Bethel NP, Callenberg KM, Nakatsukasa K, Grabe M, Brodsky JL.

Mol Biol Cell. 2017 Jul 15;28(15):2076-2090. doi: 10.1091/mbc.E17-03-0184. Epub 2017 May 24.


Plant RNA Interactome Capture: Revealing the Plant RBPome.

Bach-Pages M, Castello A, Preston GM.

Trends Plant Sci. 2017 Jun;22(6):449-451. doi: 10.1016/j.tplants.2017.04.006. Epub 2017 May 3. Review.


Arabinosylation of recombinant human immunoglobulin-based protein therapeutics.

Hossler P, Chumsae C, Racicot C, Ouellette D, Ibraghimov A, Serna D, Mora A, McDermott S, Labkovsky B, Scesney S, Grinnell C, Preston G, Bose S, Carrillo R.

MAbs. 2017 May/Jun;9(4):715-734. doi: 10.1080/19420862.2017.1294295. Epub 2017 Feb 17.


The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation.

Preston GM, Brodsky JL.

Biochem J. 2017 Feb 15;474(4):445-469. doi: 10.1042/BCJ20160582. Review.


Profiling the extended phenotype of plant pathogens: Challenges in Bacterial Molecular Plant Pathology.

Preston GM.

Mol Plant Pathol. 2017 Apr;18(3):443-456. doi: 10.1111/mpp.12530. Epub 2017 Feb 16. Review.


GABA (γ-Aminobutyric Acid) Uptake Via the GABA Permease GabP Represses Virulence Gene Expression in Pseudomonas syringae pv. tomato DC3000.

McCraw SL, Park DH, Jones R, Bentley MA, Rico A, Ratcliffe RG, Kruger NJ, Collmer A, Preston GM.

Mol Plant Microbe Interact. 2016 Dec;29(12):938-949. doi: 10.1094/MPMI-08-16-0172-R. Epub 2016 Dec 21.


Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration.

Ding K, Eaton L, Bowley D, Rieser M, Chang Q, Harris MC, Clabbers A, Dong F, Shen J, Hackett SF, Touw DS, Bixby J, Zhong S, Benatuil L, Bose S, Grinnell C, Preston GM, Iyer R, Sadhukhan R, Marchie S, Overmeyer G, Ghayur T, van Riet DA, Tang S, Campochario PA, Gu J.

MAbs. 2017 Feb/Mar;9(2):269-284. doi: 10.1080/19420862.2016.1268305.


Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein.

Buck TM, Jordahl AS, Yates ME, Preston GM, Cook E, Kleyman TR, Brodsky JL.

Biochem J. 2017 Feb 1;474(3):357-376. doi: 10.1042/BCJ20160760. Epub 2016 Nov 30.


Single-cell genomics based on Raman sorting reveals novel carotenoid-containing bacteria in the Red Sea.

Song Y, Kaster AK, Vollmers J, Song Y, Davison PA, Frentrup M, Preston GM, Thompson IP, Murrell JC, Yin H, Hunter CN, Huang WE.

Microb Biotechnol. 2017 Jan;10(1):125-137. doi: 10.1111/1751-7915.12420. Epub 2016 Oct 17.


Erratum: Pseudomonas spp. diversity is negatively associated with suppression of the wheat take-all pathogen.

Mehrabi Z, McMillan VE, Clark IM, Canning G, Hammond-Kosack KE, Preston G, Hirsch PR, Mauchline TH.

Sci Rep. 2016 Oct 10;6:34681. doi: 10.1038/srep34681. No abstract available.


Reverse and Multiple Stable Isotope Probing to Study Bacterial Metabolism and Interactions at the Single Cell Level.

Wang Y, Song Y, Tao Y, Muhamadali H, Goodacre R, Zhou NY, Preston GM, Xu J, Huang WE.

Anal Chem. 2016 Oct 4;88(19):9443-9450. Epub 2016 Sep 16.


Validation of Reference Genes for Robust qRT-PCR Gene Expression Analysis in the Rice Blast Fungus Magnaporthe oryzae.

Che Omar S, Bentley MA, Morieri G, Preston GM, Gurr SJ.

PLoS One. 2016 Aug 25;11(8):e0160637. doi: 10.1371/journal.pone.0160637. eCollection 2016.


Pseudomonas spp. diversity is negatively associated with suppression of the wheat take-all pathogen.

Mehrabi Z, McMillan VE, Clark IM, Canning G, Hammond-Kosack KE, Preston G, Hirsch PR, Mauchline TH.

Sci Rep. 2016 Aug 23;6:29905. doi: 10.1038/srep29905. Erratum in: Sci Rep. 2016 Oct 10;6:34681.


A low frequency persistent reservoir of a genomic island in a pathogen population ensures island survival and improves pathogen fitness in a susceptible host.

Neale HC, Laister R, Payne J, Preston G, Jackson RW, Arnold DL.

Environ Microbiol. 2016 Nov;18(11):4144-4152. doi: 10.1111/1462-2920.13482. Epub 2016 Aug 26.


Early changes in apoplast composition associated with defence and disease in interactions between Phaseolus vulgaris and the halo blight pathogen Pseudomonas syringae Pv. phaseolicola.

O'Leary BM, Neale HC, Geilfus CM, Jackson RW, Arnold DL, Preston GM.

Plant Cell Environ. 2016 Oct;39(10):2172-84. doi: 10.1111/pce.12770. Epub 2016 Jul 25.


Local adaptation is associated with zinc tolerance in Pseudomonas endophytes of the metal-hyperaccumulator plant Noccaea caerulescens.

Fones HN, McCurrach H, Mithani A, Smith JA, Preston GM.

Proc Biol Sci. 2016 May 11;283(1830). pii: 20160648. doi: 10.1098/rspb.2016.0648.


Quantification of a peptide standard using the intrinsic fluorescence of tyrosine.

Preston GW, Phillips DH.

Anal Bioanal Chem. 2016 Mar;408(9):2187-93. doi: 10.1007/s00216-016-9334-1. Epub 2016 Feb 15.


The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa.

Qi Q, Toll-Riera M, Heilbron K, Preston GM, MacLean RC.

Proc Biol Sci. 2016 Jan 13;283(1822). pii: 20152452. doi: 10.1098/rspb.2015.2452.


Prorenin receptor is critical for nephron progenitors.

Song R, Preston G, Kidd L, Bushnell D, Sims-Lucas S, Bates CM, Yosypiv IV.

Dev Biol. 2016 Jan 15;409(2):382-91. doi: 10.1016/j.ydbio.2015.11.024. Epub 2015 Dec 3.


Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.

Preston GC, Sinclair LV, Kaskar A, Hukelmann JL, Navarro MN, Ferrero I, MacDonald HR, Cowling VH, Cantrell DA.

EMBO J. 2015 Aug 4;34(15):2008-24. doi: 10.15252/embj.201490252. Epub 2015 Jul 1.


Correction: phytomonas: trypanosomatids adapted to plant environments.

Jaskowska E, Butler C, Preston G, Kelly S.

PLoS Pathog. 2015 May 19;11(5):e1004927. doi: 10.1371/journal.ppat.1004927. eCollection 2015 May. No abstract available.

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