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Items: 1 to 50 of 71

1.

HESI/FDA workshop on immunomodulators and cancer risk assessment: Building blocks for a weight-of-evidence approach.

Lebrec H, Brennan FR, Haggerty H, Herzyk D, Kamperschroer C, Maier CC, Ponce R, Preston BD, Weinstock D, Mellon RD.

Regul Toxicol Pharmacol. 2016 Mar;75:72-80. doi: 10.1016/j.yrtph.2015.12.018. Epub 2015 Dec 29.

2.

Tumor necrosis factor, tumor necrosis factor inhibition, and cancer risk.

Lebrec H, Ponce R, Preston BD, Iles J, Born TL, Hooper M.

Curr Med Res Opin. 2015 Mar;31(3):557-74. doi: 10.1185/03007995.2015.1011778. Epub 2015 Feb 16. Review.

PMID:
25651481
3.

DNA replication error-induced extinction of diploid yeast.

Herr AJ, Kennedy SR, Knowels GM, Schultz EM, Preston BD.

Genetics. 2014 Mar;196(3):677-91. doi: 10.1534/genetics.113.160960. Epub 2014 Jan 3.

4.

Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast.

Williams LN, Herr AJ, Preston BD.

Genetics. 2013 Mar;193(3):751-70. doi: 10.1534/genetics.112.146910. Epub 2013 Jan 10.

5.

Decoding cell lineage from acquired mutations using arbitrary deep sequencing.

Carlson CA, Kas A, Kirkwood R, Hays LE, Preston BD, Salipante SJ, Horwitz MS.

Nat Methods. 2011 Nov 27;9(1):78-80. doi: 10.1038/nmeth.1781.

6.

Mutator suppression and escape from replication error-induced extinction in yeast.

Herr AJ, Ogawa M, Lawrence NA, Williams LN, Eggington JM, Singh M, Smith RA, Preston BD.

PLoS Genet. 2011 Oct;7(10):e1002282. doi: 10.1371/journal.pgen.1002282. Epub 2011 Oct 6. Erratum in: PLoS Genet. 2011 Nov;7(11). doi:10.1371/annotation/db1d9553-4ebd-4015-a1cd-c483dbc0d7e5.

7.

Antimutator variants of DNA polymerases.

Herr AJ, Williams LN, Preston BD.

Crit Rev Biochem Mol Biol. 2011 Dec;46(6):548-70. doi: 10.3109/10409238.2011.620941. Epub 2011 Oct 6. Review.

8.

A random mutation capture assay to detect genomic point mutations in mouse tissue.

Wright JH, Modjeski KL, Bielas JH, Preston BD, Fausto N, Loeb LA, Campbell JS.

Nucleic Acids Res. 2011 Jun;39(11):e73. doi: 10.1093/nar/gkr142. Epub 2011 Apr 1.

9.

DNA replication fidelity and cancer.

Preston BD, Albertson TM, Herr AJ.

Semin Cancer Biol. 2010 Oct;20(5):281-93. doi: 10.1016/j.semcancer.2010.10.009. Epub 2010 Oct 15. Review.

10.

Case series: acute tumor lysis syndrome in mutator mice with disseminated lymphoblastic lymphoma.

Treuting PM, Albertson TM, Preston BD.

Toxicol Pathol. 2010 Apr;38(3):476-85. doi: 10.1177/0192623310362249. Epub 2010 Feb 26.

PMID:
20190201
11.

Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase.

Dhillon KK, Sidorova JM, Albertson TM, Anderson JB, Ladiges WC, Rabinovitch PS, Preston BD, Monnat RJ Jr.

DNA Repair (Amst). 2010 Jan 2;9(1):11-22. doi: 10.1016/j.dnarep.2009.09.013. Epub 2009 Nov 5.

12.

DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.

Albertson TM, Ogawa M, Bugni JM, Hays LE, Chen Y, Wang Y, Treuting PM, Heddle JA, Goldsby RE, Preston BD.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17101-4. doi: 10.1073/pnas.0907147106. Epub 2009 Sep 24.

13.

Antiretroviral drug resistance in HIV-2: three amino acid changes are sufficient for classwide nucleoside analogue resistance.

Smith RA, Anderson DJ, Pyrak CL, Preston BD, Gottlieb GS.

J Infect Dis. 2009 May 1;199(9):1323-6. doi: 10.1086/597802.

14.

Human immunodeficiency virus types 1 and 2 exhibit comparable sensitivities to Zidovudine and other nucleoside analog inhibitors in vitro.

Smith RA, Gottlieb GS, Anderson DJ, Pyrak CL, Preston BD.

Antimicrob Agents Chemother. 2008 Jan;52(1):329-32. Epub 2007 Oct 29.

15.

Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis.

Venkatesan RN, Treuting PM, Fuller ED, Goldsby RE, Norwood TH, Gooley TA, Ladiges WC, Preston BD, Loeb LA.

Mol Cell Biol. 2007 Nov;27(21):7669-82. Epub 2007 Sep 4.

16.

DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions.

Parsons JL, Preston BD, O'Connor TR, Dianov GL.

Nucleic Acids Res. 2007;35(4):1054-63. Epub 2007 Jan 30.

17.
18.

DNA replication fidelity: proofreading in trans.

Albertson TM, Preston BD.

Curr Biol. 2006 Mar 21;16(6):R209-11.

19.

Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase.

Hamburgh ME, Curr KA, Monaghan M, Rao VR, Tripathi S, Preston BD, Sarafianos S, Arnold E, Darden T, Prasad VR.

J Biol Chem. 2006 Mar 17;281(11):7421-8. Epub 2006 Jan 18.

20.

Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta.

Venkatesan RN, Hsu JJ, Lawrence NA, Preston BD, Loeb LA.

J Biol Chem. 2006 Feb 17;281(7):4486-94. Epub 2005 Dec 12.

21.
22.

Lethal mutagenesis of HIV.

Smith RA, Loeb LA, Preston BD.

Virus Res. 2005 Feb;107(2):215-28. Review.

PMID:
15649567
23.

Purifying selection masks the mutational flexibility of HIV-1 reverse transcriptase.

Smith RA, Anderson DJ, Preston BD.

J Biol Chem. 2004 Jun 18;279(25):26726-34. Epub 2004 Mar 9.

24.

Ig gene somatic hypermutation in mice defective for DNA polymerase delta proofreading.

Longacre A, Sun T, Goldsby RE, Preston BD, Storb U.

Int Immunol. 2003 Apr;15(4):477-81.

PMID:
12663677
25.
26.

High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading.

Goldsby RE, Hays LE, Chen X, Olmsted EA, Slayton WB, Spangrude GJ, Preston BD.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15560-5. Epub 2002 Nov 12.

27.

Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots.

Zhuang J, Jetzt AE, Sun G, Yu H, Klarmann G, Ron Y, Preston BD, Dougherty JP.

J Virol. 2002 Nov;76(22):11273-82.

28.

Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines.

Mohindra A, Hays LE, Phillips EN, Preston BD, Helleday T, Meuth M.

Hum Mol Genet. 2002 Sep 1;11(18):2189-200.

PMID:
12189171
29.

Mutational analysis of HIV-1 long terminal repeats to explore the relative contribution of reverse transcriptase and RNA polymerase II to viral mutagenesis.

O'Neil PK, Sun G, Yu H, Ron Y, Dougherty JP, Preston BD.

J Biol Chem. 2002 Oct 11;277(41):38053-61. Epub 2002 Jul 31.

30.
31.

Transduction of cellular sequence by a human immunodeficiency virus type 1-derived vector.

Sun G, O'Neil PK, Yu H, Ron Y, Preston BD, Dougherty JP.

J Virol. 2001 Dec;75(23):11902-6.

32.

Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice.

Goldsby RE, Lawrence NA, Hays LE, Olmsted EA, Chen X, Singh M, Preston BD.

Nat Med. 2001 Jun;7(6):638-9. No abstract available.

PMID:
11385474
33.

High rate of recombination throughout the human immunodeficiency virus type 1 genome.

Jetzt AE, Yu H, Klarmann GJ, Ron Y, Preston BD, Dougherty JP.

J Virol. 2000 Feb;74(3):1234-40.

35.

A new point mutation (P157S) in the reverse transcriptase of human immunodeficiency virus type 1 confers low-level resistance to (-)-beta-2',3'-dideoxy-3'-thiacytidine.

Smith RA, Klarmann GJ, Stray KM, von Schwedler UK, Schinazi RF, Preston BD, North TW.

Antimicrob Agents Chemother. 1999 Aug;43(8):2077-80.

36.

The nature of human immunodeficiency virus type 1 strand transfers.

Yu H, Jetzt AE, Ron Y, Preston BD, Dougherty JP.

J Biol Chem. 1998 Oct 23;273(43):28384-91.

38.

Mouse DNA polymerase delta gene (Pold1) maps to chromosome 7.

Goldsby RE, Singh M, Preston BD.

Mamm Genome. 1998 Jan;9(1):92-3. No abstract available.

PMID:
9434960
39.

Mouse DNA polymerase epsilon gene (Pole) maps to chromosome 5.

Goldsby RE, Singh M, Preston BD.

Mamm Genome. 1998 Jan;9(1):91-2. No abstract available.

PMID:
9434959
40.
41.

Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA.

Chagovetz AM, Sweasy JB, Preston BD.

J Biol Chem. 1997 Oct 31;272(44):27501-4.

42.

A genetic system to identify DNA polymerase beta mutator mutants.

Washington SL, Yoon MS, Chagovetz AM, Li SX, Clairmont CA, Preston BD, Eckert KA, Sweasy JB.

Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1321-6.

43.

Reverse transcriptase fidelity and HIV-1 variation.

Preston BD.

Science. 1997 Jan 10;275(5297):228-9; author reply 230-1. No abstract available.

44.
45.

Error-prone retrotransposition: rime of the ancient mutators.

Preston BD.

Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7427-31. Review. No abstract available.

46.
47.

Mechanisms of retroviral mutation.

Preston BD, Dougherty JP.

Trends Microbiol. 1996 Jan;4(1):16-21. Review.

PMID:
8824790
48.

Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications.

Parthasarathi S, Varela-Echavarría A, Ron Y, Preston BD, Dougherty JP.

J Virol. 1995 Dec;69(12):7991-8000.

49.
50.

Template-directed pausing of DNA synthesis by HIV-1 reverse transcriptase during polymerization of HIV-1 sequences in vitro.

Klarmann GJ, Schauber CA, Preston BD.

J Biol Chem. 1993 May 5;268(13):9793-802. Erratum in: J Biol Chem 1993 Jun 25;268(18):13764.

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