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Items: 1 to 50 of 89

1.

The WASH Benefits and SHINE trials: interpretation of WASH intervention effects on linear growth and diarrhoea.

Pickering AJ, Null C, Winch PJ, Mangwadu G, Arnold BF, Prendergast AJ, Njenga SM, Rahman M, Ntozini R, Benjamin-Chung J, Stewart CP, Huda TMN, Moulton LH, Colford JM Jr, Luby SP, Humphrey JH.

Lancet Glob Health. 2019 Aug;7(8):e1139-e1146. doi: 10.1016/S2214-109X(19)30268-2.

2.

Inflammatory biomarkers in HIV-infected children hospitalized for severe malnutrition in Uganda and Zimbabwe.

Prendergast AJ, Berejena C, Pimundu G, Shonhai A, Bwakura-Dangarembizi M, Musiime V, Szubert AJ, Cook AD, Spyer MJ, Nahirya-Ntege P, Kekitiinwa A, Gibb DM, Klein N, Walker AS.

AIDS. 2019 Jul 15;33(9):1485-1490. doi: 10.1097/QAD.0000000000002231.

PMID:
31008797
3.

Impact of water quality, sanitation, handwashing, and nutritional interventions on enteric infections in rural Zimbabwe: the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial.

Rogawski McQuade ET, Platts-Mills JA, Gratz J, Zhang J, Moulton LH, Mutasa K, Majo FD, Tavengwa N, Ntozini R, Prendergast AJ, Humphrey JH, Liu J, Houpt ER.

J Infect Dis. 2019 Apr 20. pii: jiz179. doi: 10.1093/infdis/jiz179. [Epub ahead of print]

PMID:
31004129
4.

Children With Noncritical Infections Have Increased Intestinal Permeability, Endotoxemia and Altered Innate Immune Responses.

Sturgeon JP, Bourke CD, Prendergast AJ.

Pediatr Infect Dis J. 2019 Jul;38(7):741-748. doi: 10.1097/INF.0000000000002311.

PMID:
30985520
5.

Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation.

Bourke CD, Gough EK, Pimundu G, Shonhai A, Berejena C, Terry L, Baumard L, Choudhry N, Karmali Y, Bwakura-Dangarembizi M, Musiime V, Lutaakome J, Kekitiinwa A, Mutasa K, Szubert AJ, Spyer MJ, Deayton JR, Glass M, Geum HM, Pardieu C, Gibb DM, Klein N, Edens TJ, Walker AS, Manges AR, Prendergast AJ.

Sci Transl Med. 2019 Apr 3;11(486). pii: eaav0537. doi: 10.1126/scitranslmed.aav0537.

PMID:
30944164
6.

Early Initiation and Exclusivity of Breastfeeding in Rural Zimbabwe: Impact of a Breastfeeding Intervention Delivered by Village Health Workers.

Mbuya MNN, Matare CR, Tavengwa NV, Chasekwa B, Ntozini R, Majo FD, Chigumira A, Chasokela CMZ, Prendergast AJ, Moulton LH, Stoltzfus RJ, Humphrey JH; SHINE Trial Team.

Curr Dev Nutr. 2019 Feb 28;3(4):nzy092. doi: 10.1093/cdn/nzy092. eCollection 2019 Apr.

7.

Independent and combined effects of improved water, sanitation, and hygiene (WASH) and improved complementary feeding on early neurodevelopment among children born to HIV-negative mothers in rural Zimbabwe: Substudy of a cluster-randomized trial.

Gladstone MJ, Chandna J, Kandawasvika G, Ntozini R, Majo FD, Tavengwa NV, Mbuya MNN, Mangwadu GT, Chigumira A, Chasokela CM, Moulton LH, Stoltzfus RJ, Humphrey JH, Prendergast AJ; SHINE Trial Team.

PLoS Med. 2019 Mar 21;16(3):e1002766. doi: 10.1371/journal.pmed.1002766. eCollection 2019 Mar.

8.

Transmission of CMV, HTLV-1, and HIV through breastmilk.

Prendergast AJ, Goga AE, Waitt C, Gessain A, Taylor GP, Rollins N, Abrams EJ, Lyall EH, de Perre PV.

Lancet Child Adolesc Health. 2019 Apr;3(4):264-273. doi: 10.1016/S2352-4642(19)30024-0. Review.

PMID:
30878119
9.

Health Outcomes, Pathogenesis and Epidemiology of Severe Acute Malnutrition (HOPE-SAM): rationale and methods of a longitudinal observational study.

Bwakura-Dangarembizi M, Amadi B, Bourke CD, Robertson RC, Mwapenya B, Chandwe K, Kapoma C, Chifunda K, Majo F, Ngosa D, Chakara P, Chulu N, Masimba F, Mapurisa I, Besa E, Mutasa K, Mwakamui S, Runodamoto T, Humphrey JH, Ntozini R, Wells JCK, Manges AR, Swann JR, Walker AS, Nathoo KJ, Kelly P, Prendergast AJ; HOPE-SAM study team.

BMJ Open. 2019 Feb 1;9(1):e023077. doi: 10.1136/bmjopen-2018-023077.

10.

The impact of improved water, sanitation and hygiene on oral rotavirus vaccine immunogenicity in Zimbabwean infants: sub-study of a cluster-randomized trial.

Church JA, Rukobo S, Govha M, Lee B, Carmolli MP, Chasekwa B, Ntozini R, Mutasa K, McNeal MM, Majo FD, Tavengwa NV, Moulton LH, Humphrey JH, Kirkpatrick BD, Prendergast AJ.

Clin Infect Dis. 2019 Feb 16. pii: ciz140. doi: 10.1093/cid/ciz140. [Epub ahead of print]

PMID:
30770931
11.

Interventions to improve oral vaccine performance: a systematic review and meta-analysis.

Church JA, Parker EP, Kirkpatrick BD, Grassly NC, Prendergast AJ.

Lancet Infect Dis. 2019 Feb;19(2):203-214. doi: 10.1016/S1473-3099(18)30602-9. Epub 2019 Jan 30.

12.

Neonatal vitamin A supplementation and immune responses to oral polio vaccine in Zimbabwean infants.

Church JA, Rukobo S, Govha M, Carmolli MP, Diehl SA, Chasekwa B, Ntozini R, Mutasa K, Humphrey JH, Kirkpatrick BD, Prendergast AJ.

Trans R Soc Trop Med Hyg. 2019 Mar 1;113(3):110-115. doi: 10.1093/trstmh/try126.

13.

Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on stunting and anaemia among HIV-exposed children in rural Zimbabwe: a cluster-randomised controlled trial.

Prendergast AJ, Chasekwa B, Evans C, Mutasa K, Mbuya MNN, Stoltzfus RJ, Smith LE, Majo FD, Tavengwa NV, Mutasa B, Mangwadu GT, Chasokela CM, Chigumira A, Moulton LH, Ntozini R, Humphrey JH; SHINE Trial Team.

Lancet Child Adolesc Health. 2019 Feb;3(2):77-90. doi: 10.1016/S2352-4642(18)30340-7. Epub 2018 Dec 18.

14.

Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe: a cluster-randomised trial.

Humphrey JH, Mbuya MNN, Ntozini R, Moulton LH, Stoltzfus RJ, Tavengwa NV, Mutasa K, Majo F, Mutasa B, Mangwadu G, Chasokela CM, Chigumira A, Chasekwa B, Smith LE, Tielsch JM, Jones AD, Manges AR, Maluccio JA, Prendergast AJ; Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial Team.

Lancet Glob Health. 2019 Jan;7(1):e132-e147. doi: 10.1016/S2214-109X(18)30374-7.

15.

The Human Microbiome and Child Growth - First 1000 Days and Beyond.

Robertson RC, Manges AR, Finlay BB, Prendergast AJ.

Trends Microbiol. 2019 Feb;27(2):131-147. doi: 10.1016/j.tim.2018.09.008. Epub 2018 Oct 24. Review.

16.

Microbial Translocation Does Not Drive Immune Activation in Ugandan Children Infected With HIV.

Fitzgerald FC, Lhomme E, Harris K, Kenny J, Doyle R, Kityo C, Shaw LP, Abongomera G, Musiime V, Cook A, Brown JR, Brooks A, Owen-Powell E, Gibb DM, Prendergast AJ, Sarah Walker A, Thiebaut R, Klein N; CHAPAS-3 Trial Team .

J Infect Dis. 2019 Jan 1;219(1):89-100. doi: 10.1093/infdis/jiy495.

17.

Exploring the relationship between environmental enteric dysfunction and oral vaccine responses.

Church JA, Parker EP, Kosek MN, Kang G, Grassly NC, Kelly P, Prendergast AJ.

Future Microbiol. 2018 Jul;13:1055-1070. doi: 10.2217/fmb-2018-0016. Epub 2018 Jun 21. Review.

18.

Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial.

Mallewa J, Szubert AJ, Mugyenyi P, Chidziva E, Thomason MJ, Chepkorir P, Abongomera G, Baleeta K, Etyang A, Warambwa C, Melly B, Mudzingwa S, Kelly C, Agutu C, Wilkes H, Nkomani S, Musiime V, Lugemwa A, Pett SL, Bwakura-Dangarembizi M, Prendergast AJ, Gibb DM, Walker AS, Berkley JA; REALITY trial team.

Lancet HIV. 2018 May;5(5):e231-e240. doi: 10.1016/S2352-3018(18)30038-9. Epub 2018 Apr 10. Erratum in: Lancet HIV. 2018 Jul;5(7):e340.

19.

Clinical characteristics and complications of rotavirus gastroenteritis in children in east London: A retrospective case-control study.

Karampatsas K, Osborne L, Seah ML, Tong CYW, Prendergast AJ.

PLoS One. 2018 Mar 22;13(3):e0194009. doi: 10.1371/journal.pone.0194009. eCollection 2018.

20.

Late Presentation With HIV in Africa: Phenotypes, Risk, and Risk Stratification in the REALITY Trial.

Siika A, McCabe L, Bwakura-Dangarembizi M, Kityo C, Mallewa J, Berkley J, Maitland K, Griffiths A, Baleeta K, Mudzingwa S, Abach J, Nathoo K, Thomason MJ, Prendergast AJ, Walker AS, Gibb DM; REALITY Trial Team .

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S140-S146. doi: 10.1093/cid/cix1142.

21.

Causes and Timing of Mortality and Morbidity Among Late Presenters Starting Antiretroviral Therapy in the REALITY Trial.

Post FA, Szubert AJ, Prendergast AJ, Johnston V, Lyall H, Fitzgerald F, Musiime V, Musoro G, Chepkorir P, Agutu C, Mallewa J, Rajapakse C, Wilkes H, Hakim J, Mugyenyi P, Walker AS, Gibb DM, Pett SL; Reduction of EArly mortaLITY in HIV-infected adults and children starting antiretroviral therapy (REALITY) Trial Team .

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S132-S139. doi: 10.1093/cid/cix1141.

22.

Two Cases of BCG Osteomyelitis Diagnosed Through Polymerase Chain Reaction/Electrospray Ionization-Mass Spectrometry Technology.

Spyridou C, Ragab H, Murphy RA, Riddell A, Wilks M, Millar MR, Prendergast AJ.

Clin Infect Dis. 2019 Jan 7;68(2):350. doi: 10.1093/cid/ciy105. No abstract available.

23.

Environmental enteric dysfunction pathways and child stunting: A systematic review.

Harper KM, Mutasa M, Prendergast AJ, Humphrey J, Manges AR.

PLoS Negl Trop Dis. 2018 Jan 19;12(1):e0006205. doi: 10.1371/journal.pntd.0006205. eCollection 2018 Jan. Review.

24.

Causes of impaired oral vaccine efficacy in developing countries.

Parker EP, Ramani S, Lopman BA, Church JA, Iturriza-Gómara M, Prendergast AJ, Grassly NC.

Future Microbiol. 2018 Jan;13:97-118. doi: 10.2217/fmb-2017-0128. Epub 2017 Dec 8. Review.

25.

Schistosomiasis in the first 1000 days.

Freer JB, Bourke CD, Durhuus GH, Kjetland EF, Prendergast AJ.

Lancet Infect Dis. 2018 Jun;18(6):e193-e203. doi: 10.1016/S1473-3099(17)30490-5. Epub 2017 Nov 20. Review. Erratum in: Lancet Infect Dis. 2018 Feb 1;:.

PMID:
29170089
26.

Timing of antiretroviral therapy in children with advanced HIV.

Prendergast AJ, Penazzato M.

Lancet HIV. 2018 Jan;5(1):e2-e3. doi: 10.1016/S2352-3018(17)30193-5. Epub 2017 Nov 14. No abstract available.

PMID:
29150376
27.

Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial.

Szubert AJ, Prendergast AJ, Spyer MJ, Musiime V, Musoke P, Bwakura-Dangarembizi M, Nahirya-Ntege P, Thomason MJ, Ndashimye E, Nkanya I, Senfuma O, Mudenge B, Klein N, Gibb DM, Walker AS; ARROW Trial Team.

PLoS Med. 2017 Nov 14;14(11):e1002432. doi: 10.1371/journal.pmed.1002432. eCollection 2017 Nov.

28.

Population-level linear growth faltering in low-income and middle-income countries.

Humphrey JH, Prendergast AJ.

Lancet Glob Health. 2017 Dec;5(12):e1168-e1169. doi: 10.1016/S2214-109X(17)30425-4. No abstract available.

29.

Role of HIV-specific CD8+ T cells in pediatric HIV cure strategies after widespread early viral escape.

Leitman EM, Thobakgale CF, Adland E, Ansari MA, Raghwani J, Prendergast AJ, Tudor-Williams G, Kiepiela P, Hemelaar J, Brener J, Tsai MH, Mori M, Riddell L, Luzzi G, Jooste P, Ndung'u T, Walker BD, Pybus OG, Kellam P, Naranbhai V, Matthews PC, Gall A, Goulder PJR.

J Exp Med. 2017 Nov 6;214(11):3239-3261. doi: 10.1084/jem.20162123. Epub 2017 Oct 5.

30.

Intestinal Damage and Inflammatory Biomarkers in Human Immunodeficiency Virus (HIV)-Exposed and HIV-Infected Zimbabwean Infants.

Prendergast AJ, Chasekwa B, Rukobo S, Govha M, Mutasa K, Ntozini R, Humphrey JH.

J Infect Dis. 2017 Sep 15;216(6):651-661. doi: 10.1093/infdis/jix367.

31.

Immune responses to oral poliovirus vaccine in HIV-exposed uninfected Zimbabwean infants.

Church JA, Rukobo S, Govha M, Carmolli MP, Diehl SA, Chasekwa B, Ntozini R, Mutasa K, Humphrey JH, Kirkpatrick BD, Prendergast AJ.

Hum Vaccin Immunother. 2017 Nov 2;13(11):2543-2547. doi: 10.1080/21645515.2017.1359454. Epub 2017 Aug 31.

32.

Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia.

Amadi B, Besa E, Zyambo K, Kaonga P, Louis-Auguste J, Chandwe K, Tarr PI, Denno DM, Nataro JP, Faubion W, Sailer A, Yeruva S, Brantner T, Murray J, Prendergast AJ, Turner JR, Kelly P.

EBioMedicine. 2017 Aug;22:191-199. doi: 10.1016/j.ebiom.2017.07.017. Epub 2017 Jul 19.

33.

Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.

Hakim J, Musiime V, Szubert AJ, Mallewa J, Siika A, Agutu C, Walker S, Pett SL, Bwakura-Dangarembizi M, Lugemwa A, Kaunda S, Karoney M, Musoro G, Kabahenda S, Nathoo K, Maitland K, Griffiths A, Thomason MJ, Kityo C, Mugyenyi P, Prendergast AJ, Walker AS, Gibb DM; REALITY Trial Team.

N Engl J Med. 2017 Jul 20;377(3):233-245. doi: 10.1056/NEJMoa1615822.

34.

Universal antiretroviral therapy for HIV-infected children: a review of the benefits and risks to consider during implementation.

Barlow-Mosha L, Musiime V, Davies MA, Prendergast AJ, Musoke P, Siberry G, Penazzato M.

J Int AIDS Soc. 2017 Jun 27;20(1):21552. doi: 10.7448/IAS.20.1.21552. Review.

35.

Determinants of recent aflatoxin exposure among pregnant women in rural Zimbabwe.

Smith LE, Mbuya MNN, Prendergast AJ, Turner PC, Ruboko S, Humphrey JH, Nelson RJ, Chigumira A, Kembo G, Stoltzfus RJ.

Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201601049. Epub 2017 Jul 19.

PMID:
28544789
36.

Aflatoxin Exposure During Pregnancy, Maternal Anemia, and Adverse Birth Outcomes.

Smith LE, Prendergast AJ, Turner PC, Humphrey JH, Stoltzfus RJ.

Am J Trop Med Hyg. 2017 Apr;96(4):770-776. doi: 10.4269/ajtmh.16-0730. Review.

37.

Co-trimoxazole for HIV-exposed uninfected infants.

Evans C, Prendergast AJ.

Lancet Glob Health. 2017 May;5(5):e468-e469. doi: 10.1016/S2214-109X(17)30147-X. No abstract available.

38.

Child Growth According to Maternal and Child HIV Status in Zimbabwe.

Omoni AO, Ntozini R, Evans C, Prendergast AJ, Moulton LH, Christian PS, Humphrey JH.

Pediatr Infect Dis J. 2017 Sep;36(9):869-876. doi: 10.1097/INF.0000000000001574.

39.

The impact of HIV and antiretroviral therapy on TB risk in children: a systematic review and meta-analysis.

Dodd PJ, Prendergast AJ, Beecroft C, Kampmann B, Seddon JA.

Thorax. 2017 Jun;72(6):559-575. doi: 10.1136/thoraxjnl-2016-209421. Epub 2017 Jan 23. Review.

40.

Cytomegalovirus Acquisition and Inflammation in Human Immunodeficiency Virus-Exposed Uninfected Zimbabwean Infants.

Evans C, Chasekwa B, Rukobo S, Govha M, Mutasa K, Ntozini R, Humphrey JH, Prendergast AJ.

J Infect Dis. 2017 Mar 1;215(5):698-702. doi: 10.1093/infdis/jiw630.

41.

Linear growth trajectories in Zimbabwean infants.

Gough EK, Moodie EE, Prendergast AJ, Ntozini R, Moulton LH, Humphrey JH, Manges AR.

Am J Clin Nutr. 2016 Dec;104(6):1616-1627. Epub 2016 Nov 2.

42.

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection.

Muenchhoff M, Adland E, Karimanzira O, Crowther C, Pace M, Csala A, Leitman E, Moonsamy A, McGregor C, Hurst J, Groll A, Mori M, Sinmyee S, Thobakgale C, Tudor-Williams G, Prendergast AJ, Kloverpris H, Roider J, Leslie A, Shingadia D, Brits T, Daniels S, Frater J, Willberg CB, Walker BD, Ndung'u T, Jooste P, Moore PL, Morris L, Goulder P.

Sci Transl Med. 2016 Sep 28;8(358):358ra125. doi: 10.1126/scitranslmed.aag1048.

43.

Reduced bacterial skin infections in HIV-infected African children randomized to long-term cotrimoxazole prophylaxis.

Prendergast AJ, Bwakura-Dangarembizi M, Mugyenyi P, Lutaakome J, Kekitiinwa A, Thomason MJ, Gibb DM, Walker AS; ARROW Trial Team.

AIDS. 2016 Nov 28;30(18):2823-2829.

44.

Head circumferences of children born to HIV-infected and HIV-uninfected mothers in Zimbabwe during the preantiretroviral therapy era.

Evans C, Chasekwa B, Ntozini R, Humphrey JH, Prendergast AJ.

AIDS. 2016 Sep 24;30(15):2323-8. doi: 10.1097/QAD.0000000000001196.

45.

HIV-Exposed Uninfected Infants in Zimbabwe: Insights into Health Outcomes in the Pre-Antiretroviral Therapy Era.

Evans C, Humphrey JH, Ntozini R, Prendergast AJ.

Front Immunol. 2016 Jun 6;7:190. doi: 10.3389/fimmu.2016.00190. eCollection 2016.

46.

Immune Dysfunction as a Cause and Consequence of Malnutrition.

Bourke CD, Berkley JA, Prendergast AJ.

Trends Immunol. 2016 Jun;37(6):386-398. doi: 10.1016/j.it.2016.04.003. Epub 2016 May 26. Review.

47.

Baseline Inflammatory Biomarkers Identify Subgroups of HIV-Infected African Children With Differing Responses to Antiretroviral Therapy.

Prendergast AJ, Szubert AJ, Berejena C, Pimundu G, Pala P, Shonhai A, Musiime V, Bwakura-Dangarembizi M, Poulsom H, Hunter P, Musoke P, Kihembo M, Munderi P, Gibb DM, Spyer M, Walker AS, Klein N; ARROW Trial Team.

J Infect Dis. 2016 Jul 15;214(2):226-36. doi: 10.1093/infdis/jiw148. Epub 2016 May 18.

48.

HIV-exposed, uninfected infants: new global challenges in the era of paediatric HIV elimination.

Evans C, Jones CE, Prendergast AJ.

Lancet Infect Dis. 2016 Jun;16(6):e92-e107. doi: 10.1016/S1473-3099(16)00055-4. Epub 2016 Mar 31. Review.

PMID:
27049574
49.

Tuberculosis incidence is high in HIV-infected African children but is reduced by co-trimoxazole and time on antiretroviral therapy.

Crook AM, Turkova A, Musiime V, Bwakura-Dangarembizi M, Bakeera-Kitaka S, Nahirya-Ntege P, Thomason M, Mugyenyi P, Musoke P, Kekitiinwa A, Munderi P, Nathoo K, Prendergast AJ, Walker AS, Gibb DM; ARROW Trial Team.

BMC Med. 2016 Mar 23;14:50. doi: 10.1186/s12916-016-0593-7.

50.

Interactions between intestinal pathogens, enteropathy and malnutrition in developing countries.

Prendergast AJ, Kelly P.

Curr Opin Infect Dis. 2016 Jun;29(3):229-36. doi: 10.1097/QCO.0000000000000261. Review.

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