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Items: 1 to 50 of 169

1.

Moving towards transformational WASH - Authors' reply.

Pickering AJ, Arnold BF, Prendergast AJ, Null C, Winch PJ, Njenga SM, Rahman M, Ntozini R, Benjamin-Chung J, Stewart CP, Colford JM Jr, Luby S, Humphrey JH.

Lancet Glob Health. 2019 Nov;7(11):e1494-e1495. doi: 10.1016/S2214-109X(19)30401-2. No abstract available.

2.

Seeking interventions to reduce post-discharge mortality among children in sub-Saharan Africa.

Prendergast AJ, Walson JL.

Lancet Glob Health. 2019 Oct;7(10):e1306-e1307. doi: 10.1016/S2214-109X(19)30373-0. No abstract available.

3.

Glia: A Gate Controlling Animal Behavior?

Wyart C, Prendergast A.

Curr Biol. 2019 Sep 9;29(17):R847-R850. doi: 10.1016/j.cub.2019.07.058.

PMID:
31505186
4.

Fulvestrant Plus Vistusertib vs Fulvestrant Plus Everolimus vs Fulvestrant Alone for Women With Hormone Receptor-Positive Metastatic Breast Cancer: The MANTA Phase 2 Randomized Clinical Trial.

Schmid P, Zaiss M, Harper-Wynne C, Ferreira M, Dubey S, Chan S, Makris A, Nemsadze G, Brunt AM, Kuemmel S, Ruiz I, Perelló A, Kendall A, Brown J, Kristeleit H, Conibear J, Saura C, Grenier J, Máhr K, Schenker M, Sohn J, Lee KS, Shepherd CJ, Oelmann E, Sarker SJ, Prendergast A, Marosics P, Moosa A, Lawrence C, Coetzee C, Mousa K, Cortés J.

JAMA Oncol. 2019 Aug 29. doi: 10.1001/jamaoncol.2019.2526. [Epub ahead of print]

PMID:
31465093
5.

The implications of three major new trials for the effect of water, sanitation and hygiene on childhood diarrhea and stunting: a consensus statement.

Cumming O, Arnold BF, Ban R, Clasen T, Esteves Mills J, Freeman MC, Gordon B, Guiteras R, Howard G, Hunter PR, Johnston RB, Pickering AJ, Prendergast AJ, Prüss-Ustün A, Rosenboom JW, Spears D, Sundberg S, Wolf J, Null C, Luby SP, Humphrey JH, Colford JM Jr.

BMC Med. 2019 Aug 28;17(1):173. doi: 10.1186/s12916-019-1410-x.

6.

Putting the "A" into WaSH: a call for integrated management of water, animals, sanitation, and hygiene.

Prendergast AJ, Gharpure R, Mor S, Viney M, Dube K, Lello J, Berger C, Siwila J, Joyeux M, Hodobo T, Hurt L, Brown T, Hoto P, Tavengwa N, Mutasa K, Craddock S, Chasekwa B, Robertson RC, Evans C, Chidhanguro D, Mutasa B, Majo F, Smith LE, Hirai M, Ntozini R, Humphrey JH, Berendes D.

Lancet Planet Health. 2019 Aug;3(8):e336-e337. doi: 10.1016/S2542-5196(19)30129-9. No abstract available.

7.

Current Understanding of Innate Immune Cell Dysfunction in Childhood Undernutrition.

Bourke CD, Jones KDJ, Prendergast AJ.

Front Immunol. 2019 Jul 29;10:1728. doi: 10.3389/fimmu.2019.01728. eCollection 2019. Review.

8.

The WASH Benefits and SHINE trials: interpretation of WASH intervention effects on linear growth and diarrhoea.

Pickering AJ, Null C, Winch PJ, Mangwadu G, Arnold BF, Prendergast AJ, Njenga SM, Rahman M, Ntozini R, Benjamin-Chung J, Stewart CP, Huda TMN, Moulton LH, Colford JM Jr, Luby SP, Humphrey JH.

Lancet Glob Health. 2019 Aug;7(8):e1139-e1146. doi: 10.1016/S2214-109X(19)30268-2.

9.

Inflammatory biomarkers in HIV-infected children hospitalized for severe malnutrition in Uganda and Zimbabwe.

Prendergast AJ, Berejena C, Pimundu G, Shonhai A, Bwakura-Dangarembizi M, Musiime V, Szubert AJ, Cook AD, Spyer MJ, Nahirya-Ntege P, Kekitiinwa A, Gibb DM, Klein N, Walker AS.

AIDS. 2019 Jul 15;33(9):1485-1490. doi: 10.1097/QAD.0000000000002231.

PMID:
31008797
10.

Impact of water quality, sanitation, handwashing, and nutritional interventions on enteric infections in rural Zimbabwe: the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial.

Rogawski McQuade ET, Platts-Mills JA, Gratz J, Zhang J, Moulton LH, Mutasa K, Majo FD, Tavengwa N, Ntozini R, Prendergast AJ, Humphrey JH, Liu J, Houpt ER.

J Infect Dis. 2019 Apr 20. pii: jiz179. doi: 10.1093/infdis/jiz179. [Epub ahead of print]

PMID:
31004129
11.

Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neurons.

Desban L, Prendergast A, Roussel J, Rosello M, Geny D, Wyart C, Bardet PL.

PLoS Biol. 2019 Apr 19;17(4):e3000235. doi: 10.1371/journal.pbio.3000235. eCollection 2019 Apr.

12.

Children With Noncritical Infections Have Increased Intestinal Permeability, Endotoxemia and Altered Innate Immune Responses.

Sturgeon JP, Bourke CD, Prendergast AJ.

Pediatr Infect Dis J. 2019 Jul;38(7):741-748. doi: 10.1097/INF.0000000000002311.

PMID:
30985520
13.

Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation.

Bourke CD, Gough EK, Pimundu G, Shonhai A, Berejena C, Terry L, Baumard L, Choudhry N, Karmali Y, Bwakura-Dangarembizi M, Musiime V, Lutaakome J, Kekitiinwa A, Mutasa K, Szubert AJ, Spyer MJ, Deayton JR, Glass M, Geum HM, Pardieu C, Gibb DM, Klein N, Edens TJ, Walker AS, Manges AR, Prendergast AJ.

Sci Transl Med. 2019 Apr 3;11(486). pii: eaav0537. doi: 10.1126/scitranslmed.aav0537.

14.

Early Initiation and Exclusivity of Breastfeeding in Rural Zimbabwe: Impact of a Breastfeeding Intervention Delivered by Village Health Workers.

Mbuya MNN, Matare CR, Tavengwa NV, Chasekwa B, Ntozini R, Majo FD, Chigumira A, Chasokela CMZ, Prendergast AJ, Moulton LH, Stoltzfus RJ, Humphrey JH; SHINE Trial Team.

Curr Dev Nutr. 2019 Feb 28;3(4):nzy092. doi: 10.1093/cdn/nzy092. eCollection 2019 Apr.

15.

Independent and combined effects of improved water, sanitation, and hygiene (WASH) and improved complementary feeding on early neurodevelopment among children born to HIV-negative mothers in rural Zimbabwe: Substudy of a cluster-randomized trial.

Gladstone MJ, Chandna J, Kandawasvika G, Ntozini R, Majo FD, Tavengwa NV, Mbuya MNN, Mangwadu GT, Chigumira A, Chasokela CM, Moulton LH, Stoltzfus RJ, Humphrey JH, Prendergast AJ; SHINE Trial Team.

PLoS Med. 2019 Mar 21;16(3):e1002766. doi: 10.1371/journal.pmed.1002766. eCollection 2019 Mar.

16.

Transmission of CMV, HTLV-1, and HIV through breastmilk.

Prendergast AJ, Goga AE, Waitt C, Gessain A, Taylor GP, Rollins N, Abrams EJ, Lyall EH, de Perre PV.

Lancet Child Adolesc Health. 2019 Apr;3(4):264-273. doi: 10.1016/S2352-4642(19)30024-0. Review.

17.

Extensive elemental mapping unlocks Mg/Ca ratios as climate proxy in seasonal records of Mediterranean limpets.

Hausmann N, Prendergast AL, Lemonis A, Zech J, Roberts P, Siozos P, Anglos D.

Sci Rep. 2019 Mar 6;9(1):3698. doi: 10.1038/s41598-019-39959-9.

18.

Health Outcomes, Pathogenesis and Epidemiology of Severe Acute Malnutrition (HOPE-SAM): rationale and methods of a longitudinal observational study.

Bwakura-Dangarembizi M, Amadi B, Bourke CD, Robertson RC, Mwapenya B, Chandwe K, Kapoma C, Chifunda K, Majo F, Ngosa D, Chakara P, Chulu N, Masimba F, Mapurisa I, Besa E, Mutasa K, Mwakamui S, Runodamoto T, Humphrey JH, Ntozini R, Wells JCK, Manges AR, Swann JR, Walker AS, Nathoo KJ, Kelly P, Prendergast AJ; HOPE-SAM study team.

BMJ Open. 2019 Feb 1;9(1):e023077. doi: 10.1136/bmjopen-2018-023077.

19.

The impact of improved water, sanitation and hygiene on oral rotavirus vaccine immunogenicity in Zimbabwean infants: sub-study of a cluster-randomized trial.

Church JA, Rukobo S, Govha M, Lee B, Carmolli MP, Chasekwa B, Ntozini R, Mutasa K, McNeal MM, Majo FD, Tavengwa NV, Moulton LH, Humphrey JH, Kirkpatrick BD, Prendergast AJ.

Clin Infect Dis. 2019 Feb 16. pii: ciz140. doi: 10.1093/cid/ciz140. [Epub ahead of print]

PMID:
30770931
20.

Interventions to improve oral vaccine performance: a systematic review and meta-analysis.

Church JA, Parker EP, Kirkpatrick BD, Grassly NC, Prendergast AJ.

Lancet Infect Dis. 2019 Feb;19(2):203-214. doi: 10.1016/S1473-3099(18)30602-9. Epub 2019 Jan 30.

21.

Faecal immunochemical tests versus colonoscopy for post-polypectomy surveillance: an accuracy, acceptability and economic study.

Atkin W, Cross AJ, Kralj-Hans I, MacRae E, Piggott C, Pearson S, Wooldrage K, Brown J, Lucas F, Prendergast A, Marchevsky N, Patel B, Pack K, Howe R, Skrobanski H, Kerrison R, Swart N, Snowball J, Duffy SW, Morris S, von Wagner C, Halloran S.

Health Technol Assess. 2019 Jan;23(1):1-84. doi: 10.3310/hta23010.

22.

Neonatal vitamin A supplementation and immune responses to oral polio vaccine in Zimbabwean infants.

Church JA, Rukobo S, Govha M, Carmolli MP, Diehl SA, Chasekwa B, Ntozini R, Mutasa K, Humphrey JH, Kirkpatrick BD, Prendergast AJ.

Trans R Soc Trop Med Hyg. 2019 Mar 1;113(3):110-115. doi: 10.1093/trstmh/try126.

23.

Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on stunting and anaemia among HIV-exposed children in rural Zimbabwe: a cluster-randomised controlled trial.

Prendergast AJ, Chasekwa B, Evans C, Mutasa K, Mbuya MNN, Stoltzfus RJ, Smith LE, Majo FD, Tavengwa NV, Mutasa B, Mangwadu GT, Chasokela CM, Chigumira A, Moulton LH, Ntozini R, Humphrey JH; SHINE Trial Team.

Lancet Child Adolesc Health. 2019 Feb;3(2):77-90. doi: 10.1016/S2352-4642(18)30340-7. Epub 2018 Dec 18.

24.

Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe: a cluster-randomised trial.

Humphrey JH, Mbuya MNN, Ntozini R, Moulton LH, Stoltzfus RJ, Tavengwa NV, Mutasa K, Majo F, Mutasa B, Mangwadu G, Chasokela CM, Chigumira A, Chasekwa B, Smith LE, Tielsch JM, Jones AD, Manges AR, Maluccio JA, Prendergast AJ; Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial Team.

Lancet Glob Health. 2019 Jan;7(1):e132-e147. doi: 10.1016/S2214-109X(18)30374-7.

25.

Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.

Chaudhury S, O'Connor C, Cañete A, Bittencourt-Silvestre J, Sarrou E, Prendergast Á, Choi J, Johnston P, Wells CA, Gibson B, Keeshan K.

Nat Commun. 2018 Dec 11;9(1):5280. doi: 10.1038/s41467-018-07584-1.

26.

Faecal immunochemical tests (FIT) versus colonoscopy for surveillance after screening and polypectomy: a diagnostic accuracy and cost-effectiveness study.

Cross AJ, Wooldrage K, Robbins EC, Kralj-Hans I, MacRae E, Piggott C, Stenson I, Prendergast A, Patel B, Pack K, Howe R, Swart N, Snowball J, Duffy SW, Morris S, von Wagner C, Halloran SP, Atkin WS.

Gut. 2019 Sep;68(9):1642-1652. doi: 10.1136/gutjnl-2018-317297. Epub 2018 Dec 11.

27.

The Human Microbiome and Child Growth - First 1000 Days and Beyond.

Robertson RC, Manges AR, Finlay BB, Prendergast AJ.

Trends Microbiol. 2019 Feb;27(2):131-147. doi: 10.1016/j.tim.2018.09.008. Epub 2018 Oct 24. Review.

28.

New evidence of megafaunal bone damage indicates late colonization of Madagascar.

Anderson A, Clark G, Haberle S, Higham T, Nowak-Kemp M, Prendergast A, Radimilahy C, Rakotozafy LM, Ramilisonina, Schwenninger JL, Virah-Sawmy M, Camens A.

PLoS One. 2018 Oct 10;13(10):e0204368. doi: 10.1371/journal.pone.0204368. eCollection 2018.

29.

Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature.

Sternberg JR, Prendergast AE, Brosse L, Cantaut-Belarif Y, Thouvenin O, Orts-Del'Immagine A, Castillo L, Djenoune L, Kurisu S, McDearmid JR, Bardet PL, Boccara C, Okamoto H, Delmas P, Wyart C.

Nat Commun. 2018 Sep 18;9(1):3804. doi: 10.1038/s41467-018-06225-x.

30.

Microbial Translocation Does Not Drive Immune Activation in Ugandan Children Infected With HIV.

Fitzgerald FC, Lhomme E, Harris K, Kenny J, Doyle R, Kityo C, Shaw LP, Abongomera G, Musiime V, Cook A, Brown JR, Brooks A, Owen-Powell E, Gibb DM, Prendergast AJ, Sarah Walker A, Thiebaut R, Klein N; CHAPAS-3 Trial Team .

J Infect Dis. 2019 Jan 1;219(1):89-100. doi: 10.1093/infdis/jiy495.

31.

Exploring the relationship between environmental enteric dysfunction and oral vaccine responses.

Church JA, Parker EP, Kosek MN, Kang G, Grassly NC, Kelly P, Prendergast AJ.

Future Microbiol. 2018 Jul;13:1055-1070. doi: 10.2217/fmb-2018-0016. Epub 2018 Jun 21. Review.

32.

Cardiac auscultation poorly predicts the presence of valvular heart disease in asymptomatic primary care patients.

Gardezi SKM, Myerson SG, Chambers J, Coffey S, d'Arcy J, Hobbs FDR, Holt J, Kennedy A, Loudon M, Prendergast A, Prothero A, Wilson J, Prendergast BD.

Heart. 2018 Nov;104(22):1832-1835. doi: 10.1136/heartjnl-2018-313082. Epub 2018 May 24.

PMID:
29794244
33.

Mechanistic studies on the palladium-catalyzed cross-dehydrogenative coupling of 4-phenoxy-2-coumarins: experimental and computational insights.

Prendergast AM, Zhang Z, Lin Z, McGlacken GP.

Dalton Trans. 2018 May 1;47(17):6049-6053. doi: 10.1039/c8dt00842f.

PMID:
29658021
34.

Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial.

Mallewa J, Szubert AJ, Mugyenyi P, Chidziva E, Thomason MJ, Chepkorir P, Abongomera G, Baleeta K, Etyang A, Warambwa C, Melly B, Mudzingwa S, Kelly C, Agutu C, Wilkes H, Nkomani S, Musiime V, Lugemwa A, Pett SL, Bwakura-Dangarembizi M, Prendergast AJ, Gibb DM, Walker AS, Berkley JA; REALITY trial team.

Lancet HIV. 2018 May;5(5):e231-e240. doi: 10.1016/S2352-3018(18)30038-9. Epub 2018 Apr 10. Erratum in: Lancet HIV. 2018 Jul;5(7):e340.

35.

Clinical characteristics and complications of rotavirus gastroenteritis in children in east London: A retrospective case-control study.

Karampatsas K, Osborne L, Seah ML, Tong CYW, Prendergast AJ.

PLoS One. 2018 Mar 22;13(3):e0194009. doi: 10.1371/journal.pone.0194009. eCollection 2018.

36.

Late Presentation With HIV in Africa: Phenotypes, Risk, and Risk Stratification in the REALITY Trial.

Siika A, McCabe L, Bwakura-Dangarembizi M, Kityo C, Mallewa J, Berkley J, Maitland K, Griffiths A, Baleeta K, Mudzingwa S, Abach J, Nathoo K, Thomason MJ, Prendergast AJ, Walker AS, Gibb DM; REALITY Trial Team.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S140-S146. doi: 10.1093/cid/cix1142.

37.

Causes and Timing of Mortality and Morbidity Among Late Presenters Starting Antiretroviral Therapy in the REALITY Trial.

Post FA, Szubert AJ, Prendergast AJ, Johnston V, Lyall H, Fitzgerald F, Musiime V, Musoro G, Chepkorir P, Agutu C, Mallewa J, Rajapakse C, Wilkes H, Hakim J, Mugyenyi P, Walker AS, Gibb DM, Pett SL; Reduction of EArly mortaLITY in HIV-infected adults and children starting antiretroviral therapy (REALITY) Trial Team.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S132-S139. doi: 10.1093/cid/cix1141.

38.

Two Cases of BCG Osteomyelitis Diagnosed Through Polymerase Chain Reaction/Electrospray Ionization-Mass Spectrometry Technology.

Spyridou C, Ragab H, Murphy RA, Riddell A, Wilks M, Millar MR, Prendergast AJ.

Clin Infect Dis. 2019 Jan 7;68(2):350. doi: 10.1093/cid/ciy105. No abstract available.

39.

Environmental enteric dysfunction pathways and child stunting: A systematic review.

Harper KM, Mutasa M, Prendergast AJ, Humphrey J, Manges AR.

PLoS Negl Trop Dis. 2018 Jan 19;12(1):e0006205. doi: 10.1371/journal.pntd.0006205. eCollection 2018 Jan. Review.

40.

Causes of impaired oral vaccine efficacy in developing countries.

Parker EP, Ramani S, Lopman BA, Church JA, Iturriza-Gómara M, Prendergast AJ, Grassly NC.

Future Microbiol. 2018 Jan;13:97-118. doi: 10.2217/fmb-2017-0128. Epub 2017 Dec 8. Review.

41.

Schistosomiasis in the first 1000 days.

Freer JB, Bourke CD, Durhuus GH, Kjetland EF, Prendergast AJ.

Lancet Infect Dis. 2018 Jun;18(6):e193-e203. doi: 10.1016/S1473-3099(17)30490-5. Epub 2017 Nov 20. Review. Erratum in: Lancet Infect Dis. 2018 Feb 1;:.

PMID:
29170089
42.

Timing of antiretroviral therapy in children with advanced HIV.

Prendergast AJ, Penazzato M.

Lancet HIV. 2018 Jan;5(1):e2-e3. doi: 10.1016/S2352-3018(17)30193-5. Epub 2017 Nov 14. No abstract available.

PMID:
29150376
43.

Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial.

Szubert AJ, Prendergast AJ, Spyer MJ, Musiime V, Musoke P, Bwakura-Dangarembizi M, Nahirya-Ntege P, Thomason MJ, Ndashimye E, Nkanya I, Senfuma O, Mudenge B, Klein N, Gibb DM, Walker AS; ARROW Trial Team.

PLoS Med. 2017 Nov 14;14(11):e1002432. doi: 10.1371/journal.pmed.1002432. eCollection 2017 Nov.

44.

Population-level linear growth faltering in low-income and middle-income countries.

Humphrey JH, Prendergast AJ.

Lancet Glob Health. 2017 Dec;5(12):e1168-e1169. doi: 10.1016/S2214-109X(17)30425-4. No abstract available.

45.

Bioluminescence Monitoring of Neuronal Activity in Freely Moving Zebrafish Larvae.

Knafo S, Prendergast A, Thouvenin O, Figueiredo SN, Wyart C.

Bio Protoc. 2017 Sep 20;7(18):e2550. doi: 10.21769/BioProtoc.2550.

46.

Role of HIV-specific CD8+ T cells in pediatric HIV cure strategies after widespread early viral escape.

Leitman EM, Thobakgale CF, Adland E, Ansari MA, Raghwani J, Prendergast AJ, Tudor-Williams G, Kiepiela P, Hemelaar J, Brener J, Tsai MH, Mori M, Riddell L, Luzzi G, Jooste P, Ndung'u T, Walker BD, Pybus OG, Kellam P, Naranbhai V, Matthews PC, Gall A, Goulder PJR.

J Exp Med. 2017 Nov 6;214(11):3239-3261. doi: 10.1084/jem.20162123. Epub 2017 Oct 5.

47.

Intestinal Damage and Inflammatory Biomarkers in Human Immunodeficiency Virus (HIV)-Exposed and HIV-Infected Zimbabwean Infants.

Prendergast AJ, Chasekwa B, Rukobo S, Govha M, Mutasa K, Ntozini R, Humphrey JH.

J Infect Dis. 2017 Sep 15;216(6):651-661. doi: 10.1093/infdis/jix367.

48.

Immune responses to oral poliovirus vaccine in HIV-exposed uninfected Zimbabwean infants.

Church JA, Rukobo S, Govha M, Carmolli MP, Diehl SA, Chasekwa B, Ntozini R, Mutasa K, Humphrey JH, Kirkpatrick BD, Prendergast AJ.

Hum Vaccin Immunother. 2017 Nov 2;13(11):2543-2547. doi: 10.1080/21645515.2017.1359454. Epub 2017 Aug 31.

49.

Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia.

Amadi B, Besa E, Zyambo K, Kaonga P, Louis-Auguste J, Chandwe K, Tarr PI, Denno DM, Nataro JP, Faubion W, Sailer A, Yeruva S, Brantner T, Murray J, Prendergast AJ, Turner JR, Kelly P.

EBioMedicine. 2017 Aug;22:191-199. doi: 10.1016/j.ebiom.2017.07.017. Epub 2017 Jul 19.

50.

Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.

Hakim J, Musiime V, Szubert AJ, Mallewa J, Siika A, Agutu C, Walker S, Pett SL, Bwakura-Dangarembizi M, Lugemwa A, Kaunda S, Karoney M, Musoro G, Kabahenda S, Nathoo K, Maitland K, Griffiths A, Thomason MJ, Kityo C, Mugyenyi P, Prendergast AJ, Walker AS, Gibb DM; REALITY Trial Team.

N Engl J Med. 2017 Jul 20;377(3):233-245. doi: 10.1056/NEJMoa1615822.

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