Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41

1.

Mitochondrial dysfunction RAD51, and Ku80 proteolysis promote apoptotic effects of Dinaciclib in Bcl-xL silenced cells.

Premkumar DR, Jane EP, Thambireddy S, Sutera PA, Cavaleri JM, Pollack IF.

Mol Carcinog. 2018 Apr;57(4):469-482. doi: 10.1002/mc.22771. Epub 2017 Dec 30.

PMID:
29240261
2.

Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in Bcl-xL silenced glioma cell lines.

Jane EP, Premkumar DR, Sutera PA, Cavaleri JM, Pollack IF.

Mol Carcinog. 2017 Apr;56(4):1251-1265. doi: 10.1002/mc.22587. Epub 2016 Nov 22.

PMID:
27805285
3.

Dinaciclib, a Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation of Mcl-1 and Enhances ABT-737-Mediated Cell Death in Malignant Human Glioma Cell Lines.

Jane EP, Premkumar DR, Cavaleri JM, Sutera PA, Rajasekar T, Pollack IF.

J Pharmacol Exp Ther. 2016 Feb;356(2):354-65. doi: 10.1124/jpet.115.230052. Epub 2015 Nov 19.

4.

NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5.

Foster KA, Jane EP, Premkumar DR, Morales A, Pollack IF.

Int J Oncol. 2015 Aug;47(2):506-16. doi: 10.3892/ijo.2015.3035. Epub 2015 Jun 5.

6.

Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines.

Foster KA, Jane EP, Premkumar DR, Morales A, Pollack IF.

J Neurooncol. 2014 Dec;120(3):459-72. doi: 10.1007/s11060-014-1575-2. Epub 2014 Aug 20.

PMID:
25139025
8.
9.

YM-155 potentiates the effect of ABT-737 in malignant human glioma cells via survivin and Mcl-1 downregulation in an EGFR-dependent context.

Jane EP, Premkumar DR, DiDomenico JD, Hu B, Cheng SY, Pollack IF.

Mol Cancer Ther. 2013 Mar;12(3):326-38. doi: 10.1158/1535-7163.MCT-12-0901. Epub 2013 Jan 16.

10.

ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines.

Premkumar DR, Jane EP, DiDomenico JD, Vukmer NA, Agostino NR, Pollack IF.

J Pharmacol Exp Ther. 2012 Jun;341(3):859-72. doi: 10.1124/jpet.112.191536. Epub 2012 Mar 5.

11.
12.

Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway.

Jane EP, Premkumar DR, Pollack IF.

Mol Cancer Ther. 2011 Jan;10(1):198-208. doi: 10.1158/1535-7163.MCT-10-0725.

13.

Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells.

Premkumar DR, Jane EP, Agostino NR, Scialabba JL, Pollack IF.

J Carcinog. 2010 Jul 14;9. pii: 7. doi: 10.4103/1477-3163.65448.

15.

Abrogation of mitogen-activated protein kinase and Akt signaling by vandetanib synergistically potentiates histone deacetylase inhibitor-induced apoptosis in human glioma cells.

Jane EP, Premkumar DR, Addo-Yobo SO, Pollack IF.

J Pharmacol Exp Ther. 2009 Oct;331(1):327-37. doi: 10.1124/jpet.109.155705. Epub 2009 Jul 21.

16.

Cellular systems biology profiling applied to cellular models of disease.

Giuliano KA, Premkumar DR, Strock CJ, Johnston P, Taylor L.

Comb Chem High Throughput Screen. 2009 Nov;12(9):838-48.

PMID:
19531002
18.

Coadministration of sorafenib with rottlerin potently inhibits cell proliferation and migration in human malignant glioma cells.

Jane EP, Premkumar DR, Pollack IF.

J Pharmacol Exp Ther. 2006 Dec;319(3):1070-80. Epub 2006 Sep 7.

19.

Cooperative inhibitory effect of ZD1839 (Iressa) in combination with 17-AAG on glioma cell growth.

Premkumar DR, Arnold B, Pollack IF.

Mol Carcinog. 2006 May;45(5):288-301.

PMID:
16550610
20.

Effect of trichostatin A, a histone deacetylase inhibitor, on glioma proliferation in vitro by inducing cell cycle arrest and apoptosis.

Wetzel M, Premkumar DR, Arnold B, Pollack IF.

J Neurosurg. 2005 Dec;103(6 Suppl):549-56.

PMID:
16383255
21.

Synergistic interaction between 17-AAG and phosphatidylinositol 3-kinase inhibition in human malignant glioma cells.

Premkumar DR, Arnold B, Jane EP, Pollack IF.

Mol Carcinog. 2006 Jan;45(1):47-59.

PMID:
16267832
22.

Properties of exogenously added GPI-anchored proteins following their incorporation into cells.

Premkumar DR, Fukuoka Y, Sevlever D, Brunschwig E, Rosenberry TL, Tykocinski ML, Medof ME.

J Cell Biochem. 2001;82(2):234-45.

PMID:
11527149
23.

Dual influence of nitric oxide on gene regulation during hypoxia.

Adhikary G, Premkumar DR, Prabhakar NR.

Adv Exp Med Biol. 2000;475:285-92.

PMID:
10849669
24.

Intracellular pathways linking hypoxia to activation of c-fos and AP-1.

Premkumar DR, Adhikary G, Overholt JL, Simonson MS, Cherniack NS, Prabhakar NR.

Adv Exp Med Biol. 2000;475:101-9.

PMID:
10849652
25.

L-type Ca(2+) channel activation regulates induction of c-fos transcription by hypoxia.

Premkumar DR, Mishra RR, Overholt JL, Simonson MS, Cherniack NS, Prabhakar NR.

J Appl Physiol (1985). 2000 May;88(5):1898-906.

26.

Blunted respiratory responses to hypoxia in mutant mice deficient in nitric oxide synthase-3.

Kline DD, Yang T, Premkumar DR, Thomas AJ, Prabhakar NR.

J Appl Physiol (1985). 2000 Apr;88(4):1496-508.

27.

Vascular endothelial growth factor in Alzheimer's disease and experimental cerebral ischemia.

Kalaria RN, Cohen DL, Premkumar DR, Nag S, LaManna JC, Lust WD.

Brain Res Mol Brain Res. 1998 Nov 12;62(1):101-5.

PMID:
9795165
28.

Identification and expression of the Na+/H+ exchanger in mammalian cerebrovascular and choroidal tissues: characterization by amiloride-sensitive [3H]MIA binding and RT-PCR analysis.

Kalaria RN, Premkumar DR, Lin CW, Kroon SN, Bae JY, Sayre LM, LaManna JC.

Brain Res Mol Brain Res. 1998 Jul 15;58(1-2):178-87.

PMID:
9685633
29.

Apolipoprotein E polymorphism in elderly east Africans.

Sayi JG, Patel NB, Premkumar DR, Adem A, Winblad B, Matuja WB, Mtui EP, Gatere S, Friedland RP, Koss E, Kalaria RN.

East Afr Med J. 1997 Oct;74(10):668-70.

PMID:
9529753
30.

Amyloid-beta protein angiopathies masquerading as Alzheimer's disease?

Cohen DL, Hedera P, Premkumar DR, Friedland RP, Kalaria RN.

Ann N Y Acad Sci. 1997 Sep 26;826:390-5.

PMID:
9329710
31.

Evaluation of risk factors for Alzheimer's disease in elderly east Africans.

Kalaria RN, Ogeng'o JA, Patel NB, Sayi JG, Kitinya JN, Chande HM, Matuja WB, Mtui EP, Kimani JK, Premkumar DR, Koss E, Gatere S, Friedland RP.

Brain Res Bull. 1997;44(5):573-7. Review.

PMID:
9365800
32.

Activation of nitric oxide synthase gene expression by hypoxia in central and peripheral neurons.

Prabhakar NR, Pieramici SF, Premkumar DR, Kumar GK, Kalaria RN.

Brain Res Mol Brain Res. 1996 Dec 31;43(1-2):341-6.

PMID:
9037552
33.

Cellular aspects of the inflammatory response in Alzheimer's disease.

Kalaria RN, Cohen DL, Premkumar DR.

Neurodegeneration. 1996 Dec;5(4):497-503. Review.

PMID:
9117569
34.

Molecular aspects of inflammatory and immune responses in Alzheimer's disease.

Kalaria RN, Harshbarger-Kelly M, Cohen DL, Premkumar DR.

Neurobiol Aging. 1996 Sep-Oct;17(5):687-93. Review.

PMID:
8892341
35.

Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease.

Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN.

Am J Pathol. 1996 Jun;148(6):2083-95.

36.

The nef gene from a long-term HIV type 1 nonprogressor.

Premkumar DR, Ma XZ, Maitra RK, Chakrabarti BK, Salkowitz J, Yen-Lieberman B, Hirsch MS, Kestler HW.

AIDS Res Hum Retroviruses. 1996 Mar 1;12(4):337-45.

PMID:
8906995
37.
38.

Apolipoprotein E alleles and brain vascular pathology in Alzheimer's disease.

Kalaria RN, Cohen DL, Premkumar DR.

Ann N Y Acad Sci. 1996 Jan 17;777:266-70.

PMID:
8624096
39.
40.

Apolipoprotein E genotype and cerebral amyloid angiopathy.

Kalaria RN, Premkumar DR.

Lancet. 1995 Nov 25;346(8987):1424. No abstract available.

PMID:
7475834
41.

Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease.

Premkumar DR, Smith MA, Richey PL, Petersen RB, Castellani R, Kutty RK, Wiggert B, Perry G, Kalaria RN.

J Neurochem. 1995 Sep;65(3):1399-402.

PMID:
7543935

Supplemental Content

Loading ...
Support Center