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Items: 36


Inhibition of collagen production delays malignant mesothelioma tumor growth in a murine model.

Abayasiriwardana KS, Wood MK, Prêle CM, Birnie KA, Robinson BW, Laurent GJ, McAnulty RJ, Mutsaers SE.

Biochem Biophys Res Commun. 2019 Mar 5;510(2):198-204. doi: 10.1016/j.bbrc.2019.01.057. Epub 2019 Jan 23.


STAT3 Regulates the Onset of Oxidant-Induced Senescence in Lung Fibroblasts.

Waters DW, Blokland KEC, Pathinayake PS, Wei L, Schuliga M, Jaffar J, Westall GP, Hansbro PM, Prele CM, Mutsaers SE, Bartlett NW, Burgess JK, Grainge CL, Knight DA.

Am J Respir Cell Mol Biol. 2019 Jan 4. doi: 10.1165/rcmb.2018-0328OC. [Epub ahead of print]


Ephrin-A2 affects wound healing and scarring in a murine model of excisional injury.

Wijeratne D, Rodger J, Stevenson A, Wallace H, Prêle CM, Wood FM, Fear MW.

Burns. 2019 May;45(3):682-690. doi: 10.1016/j.burns.2018.10.002. Epub 2018 Oct 25.


PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.

Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaar8356. doi: 10.1126/scitranslmed.aar8356.


Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.

Schuliga M, Pechkovsky DV, Read J, Waters DW, Blokland KEC, Reid AT, Hogaboam CM, Khalil N, Burgess JK, Prêle CM, Mutsaers SE, Jaffar J, Westall G, Grainge C, Knight DA.

J Cell Mol Med. 2018 Dec;22(12):5847-5861. doi: 10.1111/jcmm.13855. Epub 2018 Sep 26.


Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF.

Hynds RE, Gowers KHC, Nigro E, Butler CR, Bonfanti P, Giangreco A, Prêle CM, Janes SM.

PLoS One. 2018 May 17;13(5):e0197129. doi: 10.1371/journal.pone.0197129. eCollection 2018.


Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis.

Waters DW, Blokland KEC, Pathinayake PS, Burgess JK, Mutsaers SE, Prele CM, Schuliga M, Grainge CL, Knight DA.

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L162-L172. doi: 10.1152/ajplung.00037.2018. Epub 2018 Apr 26.


Targeting microRNA to improve diagnostic and therapeutic approaches for malignant mesothelioma.

Birnie KA, Prêle CM, Thompson PJ, Badrian B, Mutsaers SE.

Oncotarget. 2017 Aug 24;8(44):78193-78207. doi: 10.18632/oncotarget.20409. eCollection 2017 Sep 29. Review.


Idiopathic pulmonary fibrosis and a role for autoimmunity.

Hoyne GF, Elliott H, Mutsaers SE, Prêle CM.

Immunol Cell Biol. 2017 Aug;95(7):577-583. doi: 10.1038/icb.2017.22. Epub 2017 Mar 30. Review.


A Subset of Malignant Mesothelioma Tumors Retain Osteogenic Potential.

Lansley SM, Pedersen B, Robinson C, Searles RG, Sterrett G, van Bruggen I, Lake RA, Mutsaers SE, Prêle CM.

Sci Rep. 2016 Nov 25;6:36349. doi: 10.1038/srep36349.


Mesothelial cells and peritoneal homeostasis.

Mutsaers SE, Prêle CM, Pengelly S, Herrick SE.

Fertil Steril. 2016 Oct;106(5):1018-1024. doi: 10.1016/j.fertnstert.2016.09.005. Review.


BARD1 mediates TGF-β signaling in pulmonary fibrosis.

André PA, Prêle CM, Vierkotten S, Carnesecchi S, Donati Y, Chambers RC, Pache JC, Crestani B, Barazzone-Argiroffo C, Königshoff M, Laurent GJ, Irminger-Finger I.

Respir Res. 2015 Sep 29;16:118. doi: 10.1186/s12931-015-0278-3.


Mesothelial cells in tissue repair and fibrosis.

Mutsaers SE, Birnie K, Lansley S, Herrick SE, Lim CB, Prêle CM.

Front Pharmacol. 2015 Jun 9;6:113. doi: 10.3389/fphar.2015.00113. eCollection 2015. Review.


Loss of miR-223 and JNK Signaling Contribute to Elevated Stathmin in Malignant Pleural Mesothelioma.

Birnie KA, Yip YY, Ng DC, Kirschner MB, Reid G, Prêle CM, Musk AW, Lee YC, Thompson PJ, Mutsaers SE, Badrian B.

Mol Cancer Res. 2015 Jul;13(7):1106-18. doi: 10.1158/1541-7786.MCR-14-0442. Epub 2015 Mar 30.


Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis.

Lim CB, Prêle CM, Baltic S, Arthur PG, Creaney J, Watkins DN, Thompson PJ, Mutsaers SE.

Oncotarget. 2015 Jan 30;6(3):1519-30.


Harnessing the potential of lung stem cells for regenerative medicine.

McQualter JL, Anthony D, Bozinovski S, Prêle CM, Laurent GJ.

Int J Biochem Cell Biol. 2014 Nov;56:82-91. doi: 10.1016/j.biocel.2014.10.012. Epub 2014 Oct 15. Review.


Fibulin-1 predicts disease progression in patients with idiopathic pulmonary fibrosis.

Jaffar J, Unger S, Corte TJ, Keller M, Wolters PJ, Richeldi L, Cerri S, Prêle CM, Hansbro PM, Argraves WS, Oliver RA, Oliver BG, Black JL, Burgess JK.

Chest. 2014 Oct;146(4):1055-1063. doi: 10.1378/chest.13-2688.


Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma.

Lim CB, Prêle CM, Cheah HM, Cheng YY, Klebe S, Reid G, Watkins DN, Baltic S, Thompson PJ, Mutsaers SE.

PLoS One. 2013 Jun 24;8(6):e66685. doi: 10.1371/journal.pone.0066685. Print 2013.


STAT3: a central mediator of pulmonary fibrosis?

Prêle CM, Yao E, O'Donoghue RJ, Mutsaers SE, Knight DA.

Proc Am Thorac Soc. 2012 Jul;9(3):177-82. doi: 10.1513/pats.201201-007AW. Review. Erratum in: Proc Am Thorac Soc. 2012 Oct;9(4):210.


Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis.

O'Donoghue RJ, Knight DA, Richards CD, Prêle CM, Lau HL, Jarnicki AG, Jones J, Bozinovski S, Vlahos R, Thiem S, McKenzie BS, Wang B, Stumbles P, Laurent GJ, McAnulty RJ, Rose-John S, Zhu HJ, Anderson GP, Ernst MR, Mutsaers SE.

EMBO Mol Med. 2012 Sep;4(9):939-51. doi: 10.1002/emmm.201100604. Epub 2012 Jun 8.


The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2.

Woodward EA, Kolesnik TB, Nicholson SE, Prêle CM, Hart PH.

Cytokine. 2012 Jun;58(3):415-23. doi: 10.1016/j.cyto.2012.03.009. Epub 2012 Apr 7.


STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF.

Pechkovsky DV, Prêle CM, Wong J, Hogaboam CM, McAnulty RJ, Laurent GJ, Zhang SS, Selman M, Mutsaers SE, Knight DA.

Am J Pathol. 2012 Apr;180(4):1398-412. doi: 10.1016/j.ajpath.2011.12.022. Epub 2012 Feb 7.


Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia.

Prêle CM, Reichelt ME, Mutsaers SE, Davies M, Delbridge LM, Headrick JP, Rosenthal N, Bogoyevitch MA, Grounds MD.

Cardiovasc Pathol. 2012 Jan-Feb;21(1):17-27. doi: 10.1016/j.carpath.2010.11.008. Epub 2011 Jan 26.


Mesothelial cell differentiation into osteoblast- and adipocyte-like cells.

Lansley SM, Searles RG, Hoi A, Thomas C, Moneta H, Herrick SE, Thompson PJ, Newman M, Sterrett GF, Prêle CM, Mutsaers SE.

J Cell Mol Med. 2011 Oct;15(10):2095-105. doi: 10.1111/j.1582-4934.2010.01212.x.


STAT3 in tissue fibrosis: is there a role in the lung?

Knight D, Mutsaers SE, Prêle CM.

Pulm Pharmacol Ther. 2011 Apr;24(2):193-8. doi: 10.1016/j.pupt.2010.10.005. Epub 2010 Oct 15. Review.


The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1).

Woodward EA, Prêle CM, Nicholson SE, Kolesnik TB, Hart PH.

Immunology. 2010 Sep;131(1):118-27. doi: 10.1111/j.1365-2567.2010.03281.x. Epub 2010 Apr 6.


SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages.

Prêle CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH.

J Immunol. 2008 Dec 1;181(11):8018-26.


The origin of regenerating mesothelium: a historical perspective.

Mutsaers SE, Prêle CM, Lansley SM, Herrick SE.

Int J Artif Organs. 2007 Jun;30(6):484-94. Review.


TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide.

Tulic MK, Hurrelbrink RJ, Prêle CM, Laing IA, Upham JW, Le Souef P, Sly PD, Holt PG.

J Immunol. 2007 Jul 1;179(1):132-40.


The receptor for cis-urocanic acid remains elusive.

Woodward EA, Prêle CM, Finlay-Jones JJ, Hart PH.

J Invest Dermatol. 2006 May;126(5):1191-3. No abstract available.


Pathogenesis of pleural fibrosis.

Mutsaers SE, Prele CM, Brody AR, Idell S.

Respirology. 2004 Nov;9(4):428-40. Review.


Aberrant p53 alters DNA damage checkpoints in response to cisplatin: downregulation of CDK expression and activity.

Wrighton KH, Prêle CM, Sunters A, Yeudall WA.

Int J Cancer. 2004 Dec 10;112(5):760-70.


Identification of the molecular mechanisms contributing to polarized trafficking in osteoblasts.

Prêle CM, Horton MA, Caterina P, Stenbeck G.

Exp Cell Res. 2003 Jan 1;282(1):24-34.


Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing.

Foley-Comer AJ, Herrick SE, Al-Mishlab T, Prêle CM, Laurent GJ, Mutsaers SE.

J Cell Sci. 2002 Apr 1;115(Pt 7):1383-9.

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