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Lessons in diagnostic virology: expected and unexpected sources of error.

van Zyl G, Maritz J, Newman H, Preiser W.

Rev Med Virol. 2019 Jul;29(4):e2052. doi: 10.1002/rmv.2052. Epub 2019 May 30. Review.


Pooled PCR testing of dried blood spots for infant HIV diagnosis is cost efficient and accurate.

van Schalkwyk C, Maritz J, van Zyl GU, Preiser W, Welte A.

BMC Infect Dis. 2019 Feb 11;19(1):136. doi: 10.1186/s12879-019-3767-z.


Congenital Rubella Syndrome Surveillance in South Africa Using a Sentinel Site Approach: A Cross-sectional Study.

Motaze NV, Manamela J, Smit S, Rabie H, Harper K, duPlessis N, Reubenson G, Coetzee M, Ballot D, Moore D, Nuttall J, Linley L, Tooke L, Kriel J, Hallbauer U, Sutton C, Moodley P, Hardie D, Mazanderani AH, Goosen F, Kyaw T, Leroux D, Hussain A, Singh R, Kelly C, Ducasse G, Muller M, Blaauw M, Hamese M, Leeuw T, Mekgoe O, Rakgole P, Dungwa N, Maphosa T, Sanyane K, Preiser W, Cohen C, Suchard M.

Clin Infect Dis. 2019 May 2;68(10):1658-1664. doi: 10.1093/cid/ciy758.


HBV and HIV viral load but not microbial translocation or immune activation are associated with liver fibrosis among patients in South Africa.

Maponga TG, Andersson MI, van Rensburg CJ, Arends JE, Taljaard J, Preiser W, Glashoff RH.

BMC Infect Dis. 2018 May 8;18(1):214. doi: 10.1186/s12879-018-3115-8.


Is hepatitis B birth dose vaccine needed in Africa?

Tamandjou CR, Maponga TG, Chotun N, Preiser W, Andersson MI.

Pan Afr Med J. 2017 Jun 22;27(Suppl 3):18. doi: 10.11604/pamj.supp.2017.27.3.11546. eCollection 2017.


Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa.

Cronjé N, Schwartz IS, Retief L, Bastos ADS, Matthee S, Preiser W, Bennett NC, Maphanga T, Govender NP, Colebunders R, Kenyon C.

Med Mycol. 2018 Jun 1;56(4):510-513. doi: 10.1093/mmy/myx065.


Interpretation of indeterminate HIV-1 PCR results are influenced by changing vertical transmission prevention regimens.

Maritz J, Maharaj JN, Cotton MF, Preiser W.

J Clin Virol. 2017 Oct;95:86-89. doi: 10.1016/j.jcv.2017.08.013.


Moderate levels of pre-therapy drug resistance (PDR) in a generalised epidemic: time for better first-line ART?

van Zyl GU, Grobbelaar CJ, Claassen M, Bock P, Preiser W.

AIDS. 2017 Nov;31(17):2387-2391. doi: 10.1097/QAD.0000000000001629. Epub 2017 Aug 28.


Point-of-care screening for hepatitis B virus infection in pregnant women at an antenatal clinic: A South African experience.

Chotun N, Preiser W, van Rensburg CJ, Fernandez P, Theron GB, Glebe D, Andersson MI.

PLoS One. 2017 Jul 21;12(7):e0181267. doi: 10.1371/journal.pone.0181267. eCollection 2017.


Racial differences in seroprevalence of HAV and HEV in blood donors in the Western Cape, South Africa: a clue to the predominant HEV genotype?

Lopes T, Cable R, Pistorius C, Maponga T, Ijaz S, Preiser W, Tedder R, Andersson MI.

Epidemiol Infect. 2017 Jul;145(9):1910-1912. doi: 10.1017/S0950268817000565. Epub 2017 Mar 30.


Effects of Prednisolone on Disease Progression in Antiretroviral-Untreated HIV Infection: A 2-Year Randomized, Double-Blind Placebo-Controlled Clinical Trial.

Kasang C, Kalluvya S, Majinge C, Kongola G, Mlewa M, Massawe I, Kabyemera R, Magambo K, Ulmer A, Klinker H, Gschmack E, Horn A, Koutsilieri E, Preiser W, Hofmann D, Hain J, Müller A, Dölken L, Weissbrich B, Rethwilm A, Stich A, Scheller C.

PLoS One. 2016 Jan 26;11(1):e0146678. doi: 10.1371/journal.pone.0146678. eCollection 2016.


Mutational Heterogeneity in p6 Gag Late Assembly (L) Domains in HIV-1 Subtype C Viruses from South Africa.

Neogi U, Engelbrecht S, Claassen M, Jacobs GB, van Zyl G, Preiser W, Sonnerborg A.

AIDS Res Hum Retroviruses. 2016 Jan;32(1):80-4. doi: 10.1089/AID.2015.0266. Epub 2015 Oct 9.


Hepatitis E virus infection: An underdiagnosed infection in transplant patients in Southern Africa?

Andersson MI, Stead PA, Maponga T, van der Plas H, Preiser W.

J Clin Virol. 2015 Sep;70:23-25. doi: 10.1016/j.jcv.2015.06.081. Epub 2015 Jun 24. Review. No abstract available.


The HIV/HBV co-infected patient: Time for proactive management.

Andersson MI, Preiser W, Van Rensburg C, Taljaard J, Hoffmann CJ.

S Afr Med J. 2015 Apr;105(4):281-2. No abstract available.


Hepatitis B virus infection in HIV-exposed infants in the Western Cape, South Africa.

Chotun N, Nel E, Cotton MF, Preiser W, Andersson MI.

Vaccine. 2015 Aug 26;33(36):4618-22. doi: 10.1016/j.vaccine.2015.06.076. Epub 2015 Jul 9.


Mother-to-child transmission of hepatitis B virus in sub-Saharan Africa: time to act.

Andersson MI, Rajbhandari R, Kew MC, Vento S, Preiser W, Hoepelman AI, Theron G, Cotton M, Cohn J, Glebe D, Lesi O, Thursz M, Peters M, Chung R, Wiysonge C.

Lancet Glob Health. 2015 Jul;3(7):e358-9. doi: 10.1016/S2214-109X(15)00056-X. No abstract available.


Novel Arenavirus Isolates from Namaqua Rock Mice, Namibia, Southern Africa.

Witkowski PT, Kallies R, Hoveka J, Auste B, Ithete NL, Šoltys K, Szemes T, Drosten C, Preiser W, Klempa B, Mfune JK, Kruger DH.

Emerg Infect Dis. 2015 Jul;21(7):1213-6. doi: 10.3201/eid2107.141341.


Emerging antiretroviral drug resistance in sub-Saharan Africa: novel affordable technologies are needed to provide resistance testing for individual and public health benefits.

van Zyl GU, Frenkel LM, Chung MH, Preiser W, Mellors JW, Nachega JB.

AIDS. 2014 Nov 28;28(18):2643-8. doi: 10.1097/QAD.0000000000000502. No abstract available.


Rooting the phylogenetic tree of middle East respiratory syndrome coronavirus by characterization of a conspecific virus from an African bat.

Corman VM, Ithete NL, Richards LR, Schoeman MC, Preiser W, Drosten C, Drexler JF.

J Virol. 2014 Oct;88(19):11297-303. doi: 10.1128/JVI.01498-14. Epub 2014 Jul 16.


A qualitative PCR minipool strategy to screen for virologic failure and antiretroviral drug resistance in South African patients on first-line antiretroviral therapy.

Newman H, Breunig L, van Zyl G, Stich A, Preiser W.

J Clin Virol. 2014 Aug;60(4):387-91. doi: 10.1016/j.jcv.2014.05.011. Epub 2014 May 29.


Altered innate immune development in HIV-exposed uninfected infants.

Reikie BA, Adams RCM, Leligdowicz A, Ho K, Naidoo S, Rusk CE, de Beer C, Preiser W, Cotton MF, Speert DP, Esser M, Kollmann TR.

J Acquir Immune Defic Syndr. 2014 Jul 1;66(3):245-255. doi: 10.1097/QAI.0000000000000161.


Hantaviruses in Africa.

Witkowski PT, Klempa B, Ithete NL, Auste B, Mfune JK, Hoveka J, Matthee S, Preiser W, Kruger DH.

Virus Res. 2014 Jul 17;187:34-42. doi: 10.1016/j.virusres.2013.12.039. Epub 2014 Jan 7. Review.


Irreproducible positive results on the Cobas AmpliPrep/Cobas TaqMan HIV-1 Qual test are different qualitatively from confirmed positive results.

Maritz J, van Zyl GU, Preiser W.

J Med Virol. 2014 Jan;86(1):82-7. doi: 10.1002/jmv.23811. Epub 2013 Oct 17.


Close relative of human Middle East respiratory syndrome coronavirus in bat, South Africa.

Ithete NL, Stoffberg S, Corman VM, Cottontail VM, Richards LR, Schoeman MC, Drosten C, Drexler JF, Preiser W.

Emerg Infect Dis. 2013 Oct;19(10):1697-9. doi: 10.3201/eid1910.130946. No abstract available.


The epidemiology of hepatitis B virus infection in HIV-infected and HIV-uninfected pregnant women in the Western Cape, South Africa.

Andersson MI, Maponga TG, Ijaz S, Barnes J, Theron GB, Meredith SA, Preiser W, Tedder RS.

Vaccine. 2013 Nov 12;31(47):5579-84. doi: 10.1016/j.vaccine.2013.08.028. Epub 2013 Aug 21.


Pooled HIV-1 viral load testing using dried blood spots to reduce the cost of monitoring antiretroviral treatment in a resource-limited setting.

Pannus P, Fajardo E, Metcalf C, Coulborn RM, Durán LT, Bygrave H, Ellman T, Garone D, Murowa M, Mwenda R, Reid T, Preiser W.

J Acquir Immune Defic Syndr. 2013 Oct 1;64(2):134-7. doi: 10.1097/QAI.0b013e3182a61e63.


Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens.

Van Zyl GU, Liu TF, Claassen M, Engelbrecht S, de Oliveira T, Preiser W, Wood NT, Travers S, Shafer RW.

PLoS One. 2013 Jun 26;8(6):e67188. doi: 10.1371/journal.pone.0067188. Print 2013.


Immune reconstitution hepatitis E: a neglected complication of antiretroviral therapy in Africa?

Andersson MI, Preiser W, Maponga TG, Heys I, Taljaard JJ, van Rensburg C, Tedder RS, Ijaz S.

AIDS. 2013 Jan 28;27(3):487-9. doi: 10.1097/QAD.0b013e32835b1074. No abstract available.


Construction of a high titer infectious HIV-1 subtype C proviral clone from South Africa.

Jacobs GB, Bock S, Schuch A, Moschall R, Schrom EM, Zahn J, Reuter C, Preiser W, Rethwilm A, Engelbrecht S, Kerkau T, Bodem J.

Viruses. 2012 Sep;4(9):1830-43. doi: 10.3390/v4091830. Epub 2012 Sep 24.


Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life.

Reikie BA, Naidoo S, Ruck CE, Slogrove AL, de Beer C, la Grange H, Adams RC, Ho K, Smolen K, Speert DP, Cotton MF, Preiser W, Esser M, Kollmann TR.

Clin Vaccine Immunol. 2013 Jan;20(1):33-8. doi: 10.1128/CVI.00557-12. Epub 2012 Oct 31.


Optimising automation of a manual enzyme-linked immunosorbent assay.

de Beer C, Esser M, Preiser W.

Afr J Lab Med. 2012 Oct 15;1(1):15. doi: 10.4102/ajlm.v1i1.15. eCollection 2012.


Ontogeny of Toll-like receptor mediated cytokine responses of South African infants throughout the first year of life.

Reikie BA, Adams RC, Ruck CE, Ho K, Leligdowicz A, Pillay S, Naidoo S, Fortuno ES 3rd, de Beer C, Preiser W, Cotton MF, Speert DP, Esser M, Kollmann TR.

PLoS One. 2012;7(9):e44763. doi: 10.1371/journal.pone.0044763. Epub 2012 Sep 13.


High HBV viral loads in HIV-infected pregnant women at a tertiary hospital, South Africa.

Andersson MI, Maponga TG, Ijaz S, Theron G, Preiser W, Tedder RS.

J Acquir Immune Defic Syndr. 2012 Aug 1;60(4):e111-2. doi: 10.1097/QAI.0b013e31825aeee7. No abstract available.


HIV drug resistance (HIVDR) in antiretroviral therapy-naïve patients in Tanzania not eligible for WHO threshold HIVDR survey is dramatically high.

Kasang C, Kalluvya S, Majinge C, Stich A, Bodem J, Kongola G, Jacobs GB, Mlewa M, Mildner M, Hensel I, Horn A, Preiser W, van Zyl G, Klinker H, Koutsilieri E, Rethwilm A, Scheller C, Weissbrich B.

PLoS One. 2011;6(8):e23091. doi: 10.1371/journal.pone.0023091. Epub 2011 Aug 19.


Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the Western Cape, South Africa.

van Zyl GU, van der Merwe L, Claassen M, Zeier M, Preiser W.

J Med Virol. 2011 Oct;83(10):1764-9. doi: 10.1002/jmv.22189.


Cost-effectiveness of nucleic acid amplification tests for identifying acute HIV infections.

Maritz J, Preiser W.

J Clin Microbiol. 2011 Apr;49(4):1704. doi: 10.1128/JCM.02497-10. No abstract available.


HIV treatment adherence, drug resistance, virologic failure: evolving concepts.

Nachega JB, Marconi VC, van Zyl GU, Gardner EM, Preiser W, Hong SY, Mills EJ, Gross R.

Infect Disord Drug Targets. 2011 Apr;11(2):167-74. Review.


Pooling strategies to reduce the cost of HIV-1 RNA load monitoring in a resource-limited setting.

van Zyl GU, Preiser W, Potschka S, Lundershausen AT, Haubrich R, Smith D.

Clin Infect Dis. 2011 Jan 15;52(2):264-70. doi: 10.1093/cid/ciq084.


Young age a predictor of weak reactivity in a rapid antibody test in infants infected with HIV.

Maree L, van Zyl GU, Lotter SL, de Beer C, Esser MM, Preiser W.

J Med Virol. 2010 Aug;82(8):1314-7. doi: 10.1002/jmv.21832.


Prevalence- and gender-specific immune response to opportunistic infections in HIV-infected patients in Lesotho.

Rabenau HF, Lennemann T, Kircher C, Gürtler L, Staszewski S, Preiser W, McPherson P, Allwinn R, Doerr HW.

Sex Transm Dis. 2010 Jul;37(7):454-9. doi: 10.1097/OLQ.0b013e3181cfcc2b.


Pandemic flu (H1N1) 2009 and pregnancy.

Andersson MI, Van Zyl G, Preiser W, Langenegger E, Theron G.

S Afr Med J. 2010 Mar 29;100(4):192, 194. No abstract available.


Significantly diminished long-term specificity of the BED capture enzyme immunoassay among patients with HIV-1 with very low CD4 counts and those on antiretroviral therapy.

Marinda ET, Hargrove J, Preiser W, Slabbert H, van Zyl G, Levin J, Moulton LH, Welte A, Humphrey J.

J Acquir Immune Defic Syndr. 2010 Apr 1;53(4):496-9.


NucliSens EasyQ HIV-1 V1.2 system: Detection of human plasma-derived background signal.

van Zyl GU, Korsman SN, Maree L, Preiser W.

J Virol Methods. 2010 May;165(2):318-9. doi: 10.1016/j.jviromet.2010.02.023. Epub 2010 Feb 26.


[Tropical virus not only in the tropics. Treatment, epidemiology and diagnosis of tropical viral infections].

Preiser W.

Pharm Unserer Zeit. 2010;39(1):34-40. doi: 10.1002/pauz.201000350. Review. German. No abstract available.


Pandemic influenza A (H1N1) 2009: the experience of the first six months.

Maritz J, Maree L, Preiser W.

Clin Chem Lab Med. 2010;48(1):11-21. doi: 10.1515/CCLM.2010.023. Review.


Surveillance of transmitted resistance to antiretroviral drug classes among young children in the Western Cape Province of South Africa.

van Zyl GU, Cotton MF, Claassen M, Abrahams C, Preiser W.

Pediatr Infect Dis J. 2010 Apr;29(4):370-1. doi: 10.1097/INF.0b013e3181c4dada.


Protease inhibitor resistance in South African children with virologic failure.

van Zyl GU, van der Merwe L, Claassen M, Cotton MF, Rabie H, Prozesky HW, Preiser W.

Pediatr Infect Dis J. 2009 Dec;28(12):1125-7. doi: 10.1097/INF.0b013e3181af829d.


Reconstitution of cytomegalovirus specific T cells after pediatric allogeneic stem cell transplantation: results from a pilot study using a multi-allele CMV tetramer group.

Koehl U, Dirkwinkel E, Koenig M, Erben S, Soerensen J, Bader P, Doerr HW, Preiser W, Weissinger E, Klingebiel T, Martin H, Lehrnbecher T.

Klin Padiatr. 2008 Nov-Dec;220(6):348-52. doi: 10.1055/s-0028-1086029. Epub 2008 Oct 23.


Phylogenetic diversity and low level antiretroviral resistance mutations in HIV type 1 treatment-naive patients from Cape Town, South Africa.

Jacobs GB, Laten A, van Rensburg EJ, Bodem J, Weissbrich B, Rethwilm A, Preiser W, Engelbrecht S.

AIDS Res Hum Retroviruses. 2008 Jul;24(7):1009-12. doi: 10.1089/aid.2008.0028.


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