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Items: 1 to 50 of 98

1.

Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies.

Hoo R, Bruske E, Dimonte S, Zhu L, Mordmüller B, Sim BKL, Kremsner PG, Hoffman SL, Bozdech Z, Frank M, Preiser PR.

EBioMedicine. 2019 Oct;48:442-452. doi: 10.1016/j.ebiom.2019.09.001. Epub 2019 Sep 11.

2.

Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development.

Baumgarten S, Bryant JM, Sinha A, Reyser T, Preiser PR, Dedon PC, Scherf A.

Nat Microbiol. 2019 Aug 5. doi: 10.1038/s41564-019-0521-7. [Epub ahead of print]

PMID:
31384004
3.

Erratum for Subramanian et al., "Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules".

Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D, Chandramohanadas R.

mSphere. 2019 Mar 13;4(2). pii: e00159-19. doi: 10.1128/mSphere.00159-19. No abstract available.

4.

Enhancing the sensitivity of micro magnetic resonance relaxometry detection of low parasitemia Plasmodium falciparum in human blood.

Thamarath SS, Xiong A, Lin PH, Preiser PR, Han J.

Sci Rep. 2019 Feb 22;9(1):2555. doi: 10.1038/s41598-019-38805-2.

5.

One-step solid-oil-water emulsion for sustained bioactive ranibizumab release.

Chua HY, Lui YS, Bhuthalingam R, Agrawal R, Wong T, Preiser PR, Venkatraman S.

Expert Opin Drug Deliv. 2018 Dec;15(12):1143-1156. doi: 10.1080/17425247.2018.1538209. Epub 2018 Oct 25.

PMID:
30354700
6.

tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum.

Ng CS, Sinha A, Aniweh Y, Nah Q, Babu IR, Gu C, Chionh YH, Dedon PC, Preiser PR.

Mol Syst Biol. 2018 Oct 4;14(10):e8009. doi: 10.15252/msb.20178009.

7.

Comparative Heterochromatin Profiling Reveals Conserved and Unique Epigenome Signatures Linked to Adaptation and Development of Malaria Parasites.

Fraschka SA, Filarsky M, Hoo R, Niederwieser I, Yam XY, Brancucci NMB, Mohring F, Mushunje AT, Huang X, Christensen PR, Nosten F, Bozdech Z, Russell B, Moon RW, Marti M, Preiser PR, Bártfai R, Voss TS.

Cell Host Microbe. 2018 Mar 14;23(3):407-420.e8. doi: 10.1016/j.chom.2018.01.008. Epub 2018 Mar 1.

8.

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules.

Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D, Chandramohanadas R.

mSphere. 2018 Jan 17;3(1). pii: e00534-17. doi: 10.1128/mSphere.00534-17. eCollection 2018 Jan-Feb. Erratum in: mSphere. 2019 Mar 13;4(2):.

9.

Host immune evasion strategies of malaria blood stage parasite.

Yam XY, Preiser PR.

Mol Biosyst. 2017 Nov 21;13(12):2498-2508. doi: 10.1039/c7mb00502d. Review.

PMID:
29091093
10.

P. falciparum RH5-Basigin interaction induces changes in the cytoskeleton of the host RBC.

Aniweh Y, Gao X, Hao P, Meng W, Lai SK, Gunalan K, Chu TT, Sinha A, Lescar J, Chandramohanadas R, Li HY, Sze SK, Preiser PR.

Cell Microbiol. 2017 Sep;19(9). doi: 10.1111/cmi.12747. Epub 2017 May 9.

PMID:
28409866
11.

Three Is a Crowd - New Insights into Rosetting in Plasmodium falciparum.

Yam XY, Niang M, Madnani KG, Preiser PR.

Trends Parasitol. 2017 Apr;33(4):309-320. doi: 10.1016/j.pt.2016.12.012. Epub 2017 Jan 18. Review.

PMID:
28109696
12.

Expression dynamics and physiologically relevant functional study of STEVOR in asexual stages of Plasmodium falciparum infection.

Singh H, Madnani K, Lim YB, Cao J, Preiser PR, Lim CT.

Cell Microbiol. 2017 Jun;19(6). doi: 10.1111/cmi.12715. Epub 2017 Jan 24.

PMID:
28030753
13.

Corrigendum: Proteome mapping of Plasmodium: identification of the P. yoelii remodellome.

Siau A, Huang X, Weng M, Sze SK, Preiser PR.

Sci Rep. 2016 Nov 21;6:37202. doi: 10.1038/srep37202. No abstract available.

14.

PfRH2b specific monoclonal antibodies inhibit merozoite invasion.

Aniweh Y, Gao X, Gunalan K, Preiser PR.

Mol Microbiol. 2016 Nov;102(3):386-404. doi: 10.1111/mmi.13468. Epub 2016 Aug 18.

15.

Proteome mapping of Plasmodium: identification of the P. yoelii remodellome.

Siau A, Huang X, Weng M, Sze SK, Preiser PR.

Sci Rep. 2016 Aug 9;6:31055. doi: 10.1038/srep31055. Erratum in: Sci Rep. 2016 Nov 21;6:37202.

16.

Integrated analysis of the Plasmodium species transcriptome.

Hoo R, Zhu L, Amaladoss A, Mok S, Natalang O, Lapp SA, Hu G, Liew K, Galinski MR, Bozdech Z, Preiser PR.

EBioMedicine. 2016 May;7:255-66. doi: 10.1016/j.ebiom.2016.04.011. Epub 2016 Apr 22.

17.

Differential Spleen Remodeling Associated with Different Levels of Parasite Virulence Controls Disease Outcome in Malaria Parasite Infections.

Huang X, Huang S, Ong LC, Lim JC, Hurst RJ, Mushunje AT, Matsudaira PT, Han J, Preiser PR.

mSphere. 2015 Dec 9;1(1). pii: e00018-15. doi: 10.1128/mSphere.00018-15. eCollection 2016 Jan-Feb.

18.

Breadth of humoral response and antigenic targets of sporozoite-inhibitory antibodies associated with sterile protection induced by controlled human malaria infection.

Peng K, Goh YS, Siau A, Franetich JF, Chia WN, Ong AS, Malleret B, Wu YY, Snounou G, Hermsen CC, Adams JH, Mazier D, Preiser PR, Sauerwein RW, Grüner AC, Rénia L.

Cell Microbiol. 2016 Dec;18(12):1739-1750. doi: 10.1111/cmi.12608. Epub 2016 May 27.

19.

Characterization of the Plasmodium Interspersed Repeats (PIR) proteins of Plasmodium chabaudi indicates functional diversity.

Yam XY, Brugat T, Siau A, Lawton J, Wong DS, Farah A, Twang JS, Gao X, Langhorne J, Preiser PR.

Sci Rep. 2016 Mar 21;6:23449. doi: 10.1038/srep23449.

20.

New insights into the Plasmodium vivax transcriptome using RNA-Seq.

Zhu L, Mok S, Imwong M, Jaidee A, Russell B, Nosten F, Day NP, White NJ, Preiser PR, Bozdech Z.

Sci Rep. 2016 Feb 9;6:20498. doi: 10.1038/srep20498.

21.

Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human.

Chen Q, Ye W, Jian Tan W, Mei Yong KS, Liu M, Qi Tan S, Loh E, Te Chang K, Chye Tan T, Preiser PR, Chen J.

Sci Rep. 2015 Oct 12;5:15118. doi: 10.1038/srep15118.

22.

Synthesis, characterization and in vitro evaluation of novel enantiomerically-pure sulphonamide antimalarials.

Anusha S, Sinha A, Babu Rajeev CP, Chu TT, Mathai J, Ximei H, Fuchs JE, Shivananju N, Bender A, Preiser PR, Rangappa KS, Basappa, Chandramohanadas R.

Org Biomol Chem. 2015 Nov 21;13(43):10681-90. doi: 10.1039/c5ob01479d.

PMID:
26347024
23.

Basigin is a druggable target for host-oriented antimalarial interventions.

Zenonos ZA, Dummler SK, Müller-Sienerth N, Chen J, Preiser PR, Rayner JC, Wright GJ.

J Exp Med. 2015 Jul 27;212(8):1145-51. doi: 10.1084/jem.20150032. Epub 2015 Jul 20.

24.

De Novo Generated Human Red Blood Cells in Humanized Mice Support Plasmodium falciparum Infection.

Amaladoss A, Chen Q, Liu M, Dummler SK, Dao M, Suresh S, Chen J, Preiser PR.

PLoS One. 2015 Jun 22;10(6):e0129825. doi: 10.1371/journal.pone.0129825. eCollection 2015.

25.

Enhancing malaria diagnosis through microfluidic cell enrichment and magnetic resonance relaxometry detection.

Kong TF, Ye W, Peng WK, Hou HW, Marcos, Preiser PR, Nguyen NT, Han J.

Sci Rep. 2015 Jun 17;5:11425. doi: 10.1038/srep11425.

26.

Plasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures.

Lapp SA, Mok S, Zhu L, Wu H, Preiser PR, Bozdech Z, Galinski MR.

Malar J. 2015 Mar 13;14:110. doi: 10.1186/s12936-015-0612-8.

27.

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.

Mok S, Ashley EA, Ferreira PE, Zhu L, Lin Z, Yeo T, Chotivanich K, Imwong M, Pukrittayakamee S, Dhorda M, Nguon C, Lim P, Amaratunga C, Suon S, Hien TT, Htut Y, Faiz MA, Onyamboko MA, Mayxay M, Newton PN, Tripura R, Woodrow CJ, Miotto O, Kwiatkowski DP, Nosten F, Day NP, Preiser PR, White NJ, Dondorp AM, Fairhurst RM, Bozdech Z.

Science. 2015 Jan 23;347(6220):431-5. doi: 10.1126/science.1260403. Epub 2014 Dec 11.

28.

Micromagnetic resonance relaxometry for rapid label-free malaria diagnosis.

Peng WK, Kong TF, Ng CS, Chen L, Huang Y, Bhagat AA, Nguyen NT, Preiser PR, Han J.

Nat Med. 2014 Sep;20(9):1069-73. doi: 10.1038/nm.3622. Epub 2014 Aug 31.

PMID:
25173428
29.

STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosetting.

Niang M, Bei AK, Madnani KG, Pelly S, Dankwa S, Kanjee U, Gunalan K, Amaladoss A, Yeo KP, Bob NS, Malleret B, Duraisingh MT, Preiser PR.

Cell Host Microbe. 2014 Jul 9;16(1):81-93. doi: 10.1016/j.chom.2014.06.004.

30.

Adamantyl derivative as a potent inhibitor of Plasmodium FK506 binding protein 35.

Harikishore A, Leow ML, Niang M, Rajan S, Pasunooti KK, Preiser PR, Liu X, Yoon HS.

ACS Med Chem Lett. 2013 Sep 16;4(11):1097-101. doi: 10.1021/ml400306r. eCollection 2013 Nov 14.

31.

In vivo splenic clearance correlates with in vitro deformability of red blood cells from Plasmodium yoelii-infected mice.

Huang S, Amaladoss A, Liu M, Chen H, Zhang R, Preiser PR, Dao M, Han J.

Infect Immun. 2014 Jun;82(6):2532-41. doi: 10.1128/IAI.01525-13. Epub 2014 Mar 31.

32.

Identification of a new export signal in Plasmodium yoelii: identification of a new exportome.

Siau A, Huang X, Yam XY, Bob NS, Sun H, Rajapakse JC, Renia L, Preiser PR.

Cell Microbiol. 2014 May;16(5):673-86. doi: 10.1111/cmi.12293. Epub 2014 Apr 4.

PMID:
24636637
33.

Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells.

Chen Q, Amaladoss A, Ye W, Liu M, Dummler S, Kong F, Wong LH, Loo HL, Loh E, Tan SQ, Tan TC, Chang KT, Dao M, Suresh S, Preiser PR, Chen J.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1479-84. doi: 10.1073/pnas.1323318111. Epub 2014 Jan 13.

34.

Structural polymorphism in the promoter of pfmrp2 confers Plasmodium falciparum tolerance to quinoline drugs.

Mok S, Liong KY, Lim EH, Huang X, Zhu L, Preiser PR, Bozdech Z.

Mol Microbiol. 2014 Mar;91(5):918-34. doi: 10.1111/mmi.12505. Epub 2014 Jan 23.

35.

Triggers of key calcium signals during erythrocyte invasion by Plasmodium falciparum.

Gao X, Gunalan K, Yap SS, Preiser PR.

Nat Commun. 2013;4:2862. doi: 10.1038/ncomms3862.

36.

A high-content phenotypic screen reveals the disruptive potency of quinacrine and 3',4'-dichlorobenzamil on the digestive vacuole of Plasmodium falciparum.

Lee YQ, Goh AS, Ch'ng JH, Nosten FH, Preiser PR, Pervaiz S, Yadav SK, Tan KS.

Antimicrob Agents Chemother. 2014;58(1):550-8. doi: 10.1128/AAC.01441-13. Epub 2013 Nov 11.

37.

Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent.

Harikishore A, Niang M, Rajan S, Preiser PR, Yoon HS.

Sci Rep. 2013;3:2501. doi: 10.1038/srep02501.

38.

A multidimensional platform for the purification of non-coding RNA species.

Chionh YH, Ho CH, Pruksakorn D, Ramesh Babu I, Ng CS, Hia F, McBee ME, Su D, Pang YL, Gu C, Dong H, Prestwich EG, Shi PY, Preiser PR, Alonso S, Dedon PC.

Nucleic Acids Res. 2013 Sep;41(17):e168. doi: 10.1093/nar/gkt668. Epub 2013 Aug 1.

39.

The role of serine-type serine repeat antigen in Plasmodium yoelii blood stage development.

Huang X, Liew K, Natalang O, Siau A, Zhang N, Preiser PR.

PLoS One. 2013 Apr 25;8(4):e60723. doi: 10.1371/journal.pone.0060723. Print 2013.

40.

The role of the reticulocyte-binding-like protein homologues of Plasmodium in erythrocyte sensing and invasion.

Gunalan K, Gao X, Yap SS, Huang X, Preiser PR.

Cell Microbiol. 2013 Jan;15(1):35-44. doi: 10.1111/cmi.12038. Epub 2012 Nov 6. Review.

PMID:
23046317
41.

Structural architecture and interplay of the nucleotide- and erythrocyte binding domain of the reticulocyte binding protein Py235 from Plasmodium yoelii.

Grüber A, Manimekalai MS, Preiser PR, Grüber G.

Int J Parasitol. 2012 Nov;42(12):1083-9. doi: 10.1016/j.ijpara.2012.07.004. Epub 2012 Aug 3. Review.

PMID:
22878128
42.

A switch in infected erythrocyte deformability at the maturation and blood circulation of Plasmodium falciparum transmission stages.

Tibúrcio M, Niang M, Deplaine G, Perrot S, Bischoff E, Ndour PA, Silvestrini F, Khattab A, Milon G, David PH, Hardeman M, Vernick KD, Sauerwein RW, Preiser PR, Mercereau-Puijalon O, Buffet P, Alano P, Lavazec C.

Blood. 2012 Jun 14;119(24):e172-80. doi: 10.1182/blood-2012-03-414557. Epub 2012 Apr 18.

43.

Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling.

Witmer K, Schmid CD, Brancucci NM, Luah YH, Preiser PR, Bozdech Z, Voss TS.

Mol Microbiol. 2012 Apr;84(2):243-59. doi: 10.1111/j.1365-2958.2012.08019.x. Epub 2012 Mar 22.

44.

Transcriptional variation in the malaria parasite Plasmodium falciparum.

Rovira-Graells N, Gupta AP, Planet E, Crowley VM, Mok S, Ribas de Pouplana L, Preiser PR, Bozdech Z, Cortés A.

Genome Res. 2012 May;22(5):925-38. doi: 10.1101/gr.129692.111. Epub 2012 Mar 13.

45.

Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum.

Kuss C, Gan CS, Gunalan K, Bozdech Z, Sze SK, Preiser PR.

Mol Cell Proteomics. 2012 Feb;11(2):M111.010645. doi: 10.1074/mcp.M111.010645. Epub 2011 Oct 24.

46.

Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.

Mok S, Imwong M, Mackinnon MJ, Sim J, Ramadoss R, Yi P, Mayxay M, Chotivanich K, Liong KY, Russell B, Socheat D, Newton PN, Day NP, White NJ, Preiser PR, Nosten F, Dondorp AM, Bozdech Z.

BMC Genomics. 2011 Aug 3;12:391. doi: 10.1186/1471-2164-12-391.

47.

Biophysics of malarial parasite exit from infected erythrocytes.

Chandramohanadas R, Park Y, Lui L, Li A, Quinn D, Liew K, Diez-Silva M, Sung Y, Dao M, Lim CT, Preiser PR, Suresh S.

PLoS One. 2011;6(6):e20869. doi: 10.1371/journal.pone.0020869. Epub 2011 Jun 17.

48.

Differences in erythrocyte receptor specificity of different parts of the Plasmodium falciparum reticulocyte binding protein homologue 2a.

Gunalan K, Gao X, Liew KJ, Preiser PR.

Infect Immun. 2011 Aug;79(8):3421-30. doi: 10.1128/IAI.00201-11. Epub 2011 May 31.

49.

Changes in parasite virulence induced by the disruption of a single member of the 235 kDa rhoptry protein multigene family of Plasmodium yoelii.

Bapat D, Huang X, Gunalan K, Preiser PR.

PLoS One. 2011;6(5):e20170. doi: 10.1371/journal.pone.0020170. Epub 2011 May 20.

50.

Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum.

Foth BJ, Zhang N, Chaal BK, Sze SK, Preiser PR, Bozdech Z.

Mol Cell Proteomics. 2011 Aug;10(8):M110.006411. doi: 10.1074/mcp.M110.006411. Epub 2011 May 10.

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