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Items: 1 to 50 of 67

1.

High Hydrostatic Pressure Induces a Lipid Phase Transition and Molecular Rearrangements in Low-Density Lipoprotein Nanoparticles.

Lehofer B, Golub M, Kornmueller K, Kriechbaum M, Martinez N, Nagy G, Kohlbrecher J, Amenitsch H, Peters J, Prassl R.

Part Part Syst Charact. 2018 Sep;35(9). pii: 1800149. doi: 10.1002/ppsc.201800149. Epub 2018 Jul 18.

2.

Comparative analysis of nanosystems' effects on human endothelial and monocytic cell functions.

Matuszak J, Dörfler P, Lyer S, Unterweger H, Juenet M, Chauvierre C, Alaarg A, Franke D, Almer G, Texier I, Metselaar JM, Prassl R, Alexiou C, Mangge H, Letourneur D, Cicha I.

Nanotoxicology. 2018 Nov;12(9):957-974. doi: 10.1080/17435390.2018.1502375. Epub 2018 Sep 28.

PMID:
30265172
3.

The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.

Leithner K, Triebl A, Trötzmüller M, Hinteregger B, Leko P, Wieser BI, Grasmann G, Bertsch AL, Züllig T, Stacher E, Valli A, Prassl R, Olschewski A, Harris AL, Köfeler HC, Olschewski H, Hrzenjak A.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6225-6230. doi: 10.1073/pnas.1719871115. Epub 2018 May 29.

4.

Peptide self-assembly into lamellar phases and the formation of lipid-peptide nanostructures.

Kornmueller K, Lehofer B, Leitinger G, Amenitsch H, Prassl R.

Nano Res. 2018 Feb;11(2):913-928. doi: 10.1007/s12274-017-1702-4. Epub 2017 Jul 25.

5.

Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein.

Augustin P, Toplak M, Fuchs K, Gerstmann EC, Prassl R, Winkler A, Macheroux P.

J Biol Chem. 2018 Feb 23;293(8):2829-2840. doi: 10.1074/jbc.RA117.000846. Epub 2018 Jan 4.

6.

Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.

Bischof H, Rehberg M, Stryeck S, Artinger K, Eroglu E, Waldeck-Weiermair M, Gottschalk B, Rost R, Deak AT, Niedrist T, Vujic N, Lindermuth H, Prassl R, Pelzmann B, Groschner K, Kratky D, Eller K, Rosenkranz AR, Madl T, Plesnila N, Graier WF, Malli R.

Nat Commun. 2017 Nov 10;8(1):1422. doi: 10.1038/s41467-017-01615-z.

7.

Low-density lipoproteins investigated under high hydrostatic pressure by elastic incoherent neutron scattering.

Peters J, Martinez N, Lehofer B, Prassl R.

Eur Phys J E Soft Matter. 2017 Jul;40(7):68. doi: 10.1140/epje/i2017-11558-8. Epub 2017 Jul 26.

8.

The effect of saliva on the fate of nanoparticles.

Teubl BJ, Stojkovic B, Docter D, Pritz E, Leitinger G, Poberaj I, Prassl R, Stauber RH, Fröhlich E, Khinast JG, Roblegg E.

Clin Oral Investig. 2018 Mar;22(2):929-940. doi: 10.1007/s00784-017-2172-5. Epub 2017 Jul 9.

9.

High hydrostatic pressure specifically affects molecular dynamics and shape of low-density lipoprotein particles.

Golub M, Lehofer B, Martinez N, Ollivier J, Kohlbrecher J, Prassl R, Peters J.

Sci Rep. 2017 Apr 6;7:46034. doi: 10.1038/srep46034.

10.

Peptides at the Interface: Self-Assembly of Amphiphilic Designer Peptides and Their Membrane Interaction Propensity.

Kornmueller K, Lehofer B, Meindl C, Fröhlich E, Leitinger G, Amenitsch H, Prassl R.

Biomacromolecules. 2016 Nov 14;17(11):3591-3601. Epub 2016 Oct 21.

11.

Nanoparticles for intravascular applications: physicochemical characterization and cytotoxicity testing.

Matuszak J, Baumgartner J, Zaloga J, Juenet M, da Silva AE, Franke D, Almer G, Texier I, Faivre D, Metselaar JM, Navarro FP, Chauvierre C, Prassl R, Dézsi L, Urbanics R, Alexiou C, Mangge H, Szebeni J, Letourneur D, Cicha I.

Nanomedicine (Lond). 2016 Mar;11(6):597-616. doi: 10.2217/nnm.15.216. Epub 2016 Mar 22.

12.

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.

Roier S, Zingl FG, Cakar F, Durakovic S, Kohl P, Eichmann TO, Klug L, Gadermaier B, Weinzerl K, Prassl R, Lass A, Daum G, Reidl J, Feldman MF, Schild S.

Nat Commun. 2016 Jan 25;7:10515. doi: 10.1038/ncomms10515.

13.

Tracking morphologies at the nanoscale: self-assembly of an amphiphilic designer peptide into a double helix superstructure.

Kornmueller K, Letofsky-Papst I, Gradauer K, Mikl C, Cacho-Nerin F, Leypold M, Keller W, Leitinger G, Amenitsch H, Prassl R.

Nano Res. 2015 Jun 1;8(6):1822-1833.

14.

Lipoprotein-Related and Apolipoprotein-Mediated Delivery Systems for Drug Targeting and Imaging.

Almer G, Mangge H, Zimmer A, Prassl R.

Curr Med Chem. 2015;22(31):3631-51. Review.

15.

A basis for vaccine development: Comparative characterization of Haemophilus influenzae outer membrane vesicles.

Roier S, Blume T, Klug L, Wagner GE, Elhenawy W, Zangger K, Prassl R, Reidl J, Daum G, Feldman MF, Schild S.

Int J Med Microbiol. 2015 May;305(3):298-309. doi: 10.1016/j.ijmm.2014.12.005. Epub 2014 Dec 18.

PMID:
25592265
16.

Antibacterial activity of silver and zinc nanoparticles against Vibrio cholerae and enterotoxic Escherichia coli.

Salem W, Leitner DR, Zingl FG, Schratter G, Prassl R, Goessler W, Reidl J, Schild S.

Int J Med Microbiol. 2015 Jan;305(1):85-95. doi: 10.1016/j.ijmm.2014.11.005. Epub 2014 Nov 11.

17.

Impact of atomization technique on the stability and transport efficiency of nebulized liposomes harboring different surface characteristics.

Lehofer B, Bloder F, Jain PP, Marsh LM, Leitinger G, Olschewski H, Leber R, Olschewski A, Prassl R.

Eur J Pharm Biopharm. 2014 Nov;88(3):1076-85.

PMID:
25460154
18.

Interleukin 10-coated nanoparticle systems compared for molecular imaging of atherosclerotic lesions.

Almer G, Summers KL, Scheicher B, Kellner J, Stelzer I, Leitinger G, Gries A, Prassl R, Zimmer A, Mangge H.

Int J Nanomedicine. 2014 Sep 3;9:4211-22. doi: 10.2147/IJN.S66830. eCollection 2014.

19.

Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries.

Jain PP, Leber R, Nagaraj C, Leitinger G, Lehofer B, Olschewski H, Olschewski A, Prassl R, Marsh LM.

Int J Nanomedicine. 2014 Jul 7;9:3249-61. doi: 10.2147/IJN.S63190. eCollection 2014.

20.

Laboratory medicine for molecular imaging of atherosclerosis.

Mangge H, Almer G, Stelzer I, Reininghaus E, Prassl R.

Clin Chim Acta. 2014 Nov 1;437:19-24. doi: 10.1016/j.cca.2014.06.029. Epub 2014 Jul 5. Review.

PMID:
25003647
21.

Biophysical analysis of the interaction of the serum protein human β2GPI with bacterial lipopolysaccharide.

Gries A, Prassl R, Fukuoka S, Rössle M, Kaconis Y, Heinbockel L, Gutsmann T, Brandenburg K.

FEBS Open Bio. 2014 May 2;4:432-40. doi: 10.1016/j.fob.2014.04.008. eCollection 2014.

22.

Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles.

Rangger C, Helbok A, Sosabowski J, Kremser C, Koehler G, Prassl R, Andreae F, Virgolini IJ, von Guggenberg E, Decristoforo C.

Int J Nanomedicine. 2013;8:4659-71. doi: 10.2147/IJN.S51927. Epub 2013 Dec 5.

23.

The Role of Vitamin D in Atherosclerosis Inflammation Revisited: More a Bystander than a Player?

Mangge H, Weghuber D, Prassl R, Haara A, Schnedl W, Postolache TT, Fuchs D.

Curr Vasc Pharmacol. 2015;13(3):392-8. Review.

PMID:
24329737
24.

Renewal of the air-water interface as a critical system parameter of protein stability: aggregation of the human growth hormone and its prevention by surface-active compounds.

Wiesbauer J, Prassl R, Nidetzky B.

Langmuir. 2013 Dec 10;29(49):15240-50. doi: 10.1021/la4028223. Epub 2013 Nov 25.

PMID:
24224491
25.

Liposomes coated with thiolated chitosan enhance oral peptide delivery to rats.

Gradauer K, Barthelmes J, Vonach C, Almer G, Mangge H, Teubl B, Roblegg E, Dünnhaupt S, Fröhlich E, Bernkop-Schnürch A, Prassl R.

J Control Release. 2013 Dec 28;172(3):872-8. doi: 10.1016/j.jconrel.2013.10.011. Epub 2013 Oct 16.

26.

Obesity-related dysregulation of the tryptophan-kynurenine metabolism: role of age and parameters of the metabolic syndrome.

Mangge H, Summers KL, Meinitzer A, Zelzer S, Almer G, Prassl R, Schnedl WJ, Reininghaus E, Paulmichl K, Weghuber D, Fuchs D.

Obesity (Silver Spring). 2014 Jan;22(1):195-201. doi: 10.1002/oby.20491. Epub 2013 Jul 5.

27.

Antioxidant food supplements and obesity-related inflammation.

Mangge H, Summers K, Almer G, Prassl R, Weghuber D, Schnedl W, Fuchs D.

Curr Med Chem. 2013;20(18):2330-7. Review.

PMID:
23531214
28.

Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties.

Gradauer K, Dünnhaupt S, Vonach C, Szöllösi H, Pali-Schöll I, Mangge H, Jensen-Jarolim E, Bernkop-Schnürch A, Prassl R.

J Control Release. 2013 Feb 10;165(3):207-15. doi: 10.1016/j.jconrel.2012.12.001. Epub 2012 Dec 8.

29.

Influence of PEGylation and RGD loading on the targeting properties of radiolabeled liposomal nanoparticles.

Rangger C, Helbok A, von Guggenberg E, Sosabowski J, Radolf T, Prassl R, Andreae F, Thurner GC, Haubner R, Decristoforo C.

Int J Nanomedicine. 2012;7:5889-900. doi: 10.2147/IJN.S36847. Epub 2012 Nov 27.

30.

Interleukin-10: an anti-inflammatory marker to target atherosclerotic lesions via PEGylated liposomes.

Almer G, Frascione D, Pali-Schöll I, Vonach C, Lukschal A, Stremnitzer C, Diesner SC, Jensen-Jarolim E, Prassl R, Mangge H.

Mol Pharm. 2013 Jan 7;10(1):175-86. doi: 10.1021/mp300316n. Epub 2012 Dec 4.

31.

Clinical potential of VIP by modified pharmaco-kinetics and delivery mechanisms.

Burian B, Ortner A, Prassl R, Zimmer A, Mosgoeller W.

Endocr Metab Immune Disord Drug Targets. 2012 Dec;12(4):344-50. Review.

PMID:
23094831
32.

Scattering techniques in biology--Marking the contributions to the field from Peter Laggner on the occasion of his 68th birthday.

Pabst G, Prassl R, Amenitsch H, Rappolt M, Lohner K.

Eur Biophys J. 2012 Oct;41(10):777-929. doi: 10.1007/s00249-012-0853-1. Epub 2012 Sep 27. No abstract available.

PMID:
23015062
33.

Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties.

Gradauer K, Vonach C, Leitinger G, Kolb D, Fröhlich E, Roblegg E, Bernkop-Schnürch A, Prassl R.

Int J Nanomedicine. 2012;7:2523-34. doi: 10.2147/IJN.S29980. Epub 2012 May 21.

34.

Ultrasmall superparamagnetic iron oxide (USPIO)-based liposomes as magnetic resonance imaging probes.

Frascione D, Diwoky C, Almer G, Opriessnig P, Vonach C, Gradauer K, Leitinger G, Mangge H, Stollberger R, Prassl R.

Int J Nanomedicine. 2012;7:2349-59. doi: 10.2147/IJN.S30617. Epub 2012 May 9.

35.

Use of X-ray scattering to aid the design and delivery of membrane-active drugs.

Pabst G, Zweytick D, Prassl R, Lohner K.

Eur Biophys J. 2012 Oct;41(10):915-29. doi: 10.1007/s00249-012-0821-9. Epub 2012 Jun 2. Review.

PMID:
22660649
36.

Nanoparticle-mediated treatment of pulmonary arterial hypertension.

Mosgoeller W, Prassl R, Zimmer A.

Methods Enzymol. 2012;508:325-54. doi: 10.1016/B978-0-12-391860-4.00017-3. Review.

PMID:
22449934
37.

Effect of protamine on the solubility and deamidation of human growth hormone.

Ablinger E, Wegscheider S, Keller W, Prassl R, Zimmer A.

Int J Pharm. 2012 May 10;427(2):209-16. doi: 10.1016/j.ijpharm.2012.01.061. Epub 2012 Feb 8.

PMID:
22342332
38.

Globular domain of adiponectin: promising target molecule for detection of atherosclerotic lesions.

Almer G, Saba-Lepek M, Haj-Yahya S, Rohde E, Strunk D, Fröhlich E, Prassl R, Mangge H.

Biologics. 2011;5:95-105. doi: 10.2147/BTT.S22863. Epub 2011 Sep 7.

39.

Softness of atherogenic lipoproteins: a comparison of very low density lipoprotein (VLDL) and low density lipoprotein (LDL) using elastic incoherent neutron scattering (EINS).

Mikl C, Peters J, Trapp M, Kornmueller K, Schneider WJ, Prassl R.

J Am Chem Soc. 2011 Aug 31;133(34):13213-5. doi: 10.1021/ja203679g. Epub 2011 Aug 3.

40.

Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques.

Almer G, Wernig K, Saba-Lepek M, Haj-Yahya S, Rattenberger J, Wagner J, Gradauer K, Frascione D, Pabst G, Leitinger G, Mangge H, Zimmer A, Prassl R.

Int J Nanomedicine. 2011;6:1279-90. doi: 10.2147/IJN.S18739. Epub 2011 Jun 21.

41.

Targeting properties of peptide-modified radiolabeled liposomal nanoparticles.

Helbok A, Rangger C, von Guggenberg E, Saba-Lepek M, Radolf T, Thurner G, Andreae F, Prassl R, Decristoforo C.

Nanomedicine. 2012 Jan;8(1):112-8. doi: 10.1016/j.nano.2011.04.012. Epub 2011 May 20.

PMID:
21645641
42.

Combined light and electron microscopy using diaminobenzidine photooxidation to monitor trafficking of lipids derived from lipoprotein particles.

Röhrl C, Meisslitzer-Ruppitsch C, Bittman R, Li Z, Pabst G, Prassl R, Strobl W, Neumüller J, Ellinger A, Pavelka M, Stangl H.

Curr Pharm Biotechnol. 2012 Feb;13(2):331-40.

43.

Human low density lipoprotein: the mystery of core lipid packing.

Prassl R.

J Lipid Res. 2011 Feb;52(2):187-8. doi: 10.1194/jlr.E013417. Epub 2010 Dec 3. No abstract available.

44.

Long-term stability of sterically stabilized liposomes by freezing and freeze-drying: Effects of cryoprotectants on structure.

Stark B, Pabst G, Prassl R.

Eur J Pharm Sci. 2010 Nov 20;41(3-4):546-55. doi: 10.1016/j.ejps.2010.08.010. Epub 2010 Aug 26.

PMID:
20800680
45.

Radiolabeling of lipid-based nanoparticles for diagnostics and therapeutic applications: a comparison using different radiometals.

Helbok A, Decristoforo C, Dobrozemsky G, Rangger C, Diederen E, Stark B, Prassl R, von Guggenberg E.

J Liposome Res. 2010 Sep;20(3):219-27. doi: 10.3109/08982100903311812.

PMID:
19863193
46.

Low density lipoproteins as circulating fast temperature sensors.

Prassl R, Pregetter M, Amenitsch H, Kriechbaum M, Schwarzenbacher R, Chapman JM, Laggner P.

PLoS One. 2008;3(12):e4079. doi: 10.1371/journal.pone.0004079. Epub 2008 Dec 30.

47.

Molecular structure of low density lipoprotein: current status and future challenges.

Prassl R, Laggner P.

Eur Biophys J. 2009 Feb;38(2):145-58. doi: 10.1007/s00249-008-0368-y. Epub 2008 Sep 17.

PMID:
18797861
48.

In vitro release of propofol and binding capacity with regard to plasma constituents.

Schicher M, Polsinger M, Hermetter A, Prassl R, Zimmer A.

Eur J Pharm Biopharm. 2008 Nov;70(3):882-8. doi: 10.1016/j.ejpb.2008.06.018. Epub 2008 Jul 2.

PMID:
18640268
49.

Liposomal vasoactive intestinal peptide for lung application: protection from proteolytic degradation.

Stark B, Andreae F, Mosgoeller W, Edetsberger M, Gaubitzer E, Koehler G, Prassl R.

Eur J Pharm Biopharm. 2008 Sep;70(1):153-64. doi: 10.1016/j.ejpb.2008.04.015. Epub 2008 Apr 27.

PMID:
18555674
50.

Inhalable liposomal formulation for vasoactive intestinal peptide.

Hajos F, Stark B, Hensler S, Prassl R, Mosgoeller W.

Int J Pharm. 2008 Jun 5;357(1-2):286-94. doi: 10.1016/j.ijpharm.2008.01.046. Epub 2008 Feb 3.

PMID:
18328650

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