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Items: 1 to 50 of 101

1.

Loss of MafA and MafB expression promotes islet inflammation.

Singh T, Colberg JK, Sarmiento L, Chaves P, Hansen L, Bsharat S, Cataldo LR, Dudenhöffer-Pfeifer M, Fex M, Bryder D, Holmberg D, Sitnicka E, Cilio C, Prasad RB, Artner I.

Sci Rep. 2019 Jun 24;9(1):9074. doi: 10.1038/s41598-019-45528-x.

2.

Mutations in FGFR3 gene associated with maxillary retrognathism.

Subrahmanya RM, Prasad SV, Prasad RB, Mogra S, Shetty V, Rao V.

Indian J Dent Res. 2019 Mar-Apr;30(2):185-190. doi: 10.4103/ijdr.IJDR_113_18.

3.

Genome editing of human pancreatic beta cell models: problems, possibilities and outlook.

Balboa D, Prasad RB, Groop L, Otonkoski T.

Diabetologia. 2019 Aug;62(8):1329-1336. doi: 10.1007/s00125-019-4908-z. Epub 2019 Jun 3. Review.

4.

Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus.

Arora GP, Åkerlund M, Brøns C, Moen GH, Wasenius NS, Sommer C, Jenum AK, Almgren P, Thaman RG, Orho-Melander M, Eriksson J, Qvigstad E, Birkeland K, Berntorp K, Vaag AA, Groop L, Prasad RB.

J Intern Med. 2019 Aug;286(2):192-206. doi: 10.1111/joim.12903. Epub 2019 Apr 29.

PMID:
30919529
5.

RORB and RORC associate with human islet dysfunction and inhibit insulin secretion in INS-1 cells.

Taneera J, Mohammed AK, Dhaiban S, Hamad M, Prasad RB, Sulaiman N, Salehi A.

Islets. 2019;11(1):10-20. doi: 10.1080/19382014.2019.1566684. Epub 2019 Feb 14.

PMID:
30762474
6.

MafA Expression Preserves Immune Homeostasis in Human and Mouse Islets.

Singh T, Sarmiento L, Luan C, Prasad RB, Johansson J, Cataldo LR, Renström E, Soneji S, Cilio C, Artner I.

Genes (Basel). 2018 Dec 18;9(12). pii: E644. doi: 10.3390/genes9120644.

7.

Precision medicine in type 2 diabetes.

Prasad RB, Groop L.

J Intern Med. 2019 Jan;285(1):40-48. doi: 10.1111/joim.12859. Epub 2018 Dec 7. Review.

PMID:
30403316
8.

Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort.

Moen GH, LeBlanc M, Sommer C, Prasad RB, Lekva T, Normann KR, Qvigstad E, Groop L, Birkeland KI, Evans DM, Frøslie KF.

Eur J Endocrinol. 2018 Dec 1;179(6):363-372. doi: 10.1530/EJE-18-0478.

PMID:
30324795
9.

Turning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets.

Mafessoni F, Prasad RB, Groop L, Hansson O, Prüfer K.

Genome Biol Evol. 2018 Oct 1;10(10):2697-2708. doi: 10.1093/gbe/evy199.

10.

Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women.

Arora GP, Almgren P, Brøns C, Thaman RG, Vaag AA, Groop L, Prasad RB.

BMC Med Genomics. 2018 Aug 8;11(1):64. doi: 10.1186/s12920-018-0380-8.

11.

Heterogeneity of diabetes - An Indian perspective.

Prasad RB, Ahlqvist E, Groop L.

Diabetes Metab Syndr. 2018 Jul 11. pii: S1871-4021(18)30299-6. doi: 10.1016/j.dsx.2018.07.001. [Epub ahead of print] No abstract available.

PMID:
30030161
12.

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.

Sharma A, Halu A, Decano JL, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J, Weiss ST, Vidal M, Silverman EK, Aikawa M, Barabási AL, Groop L, Loscalzo J.

NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018.

13.

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

Gusarova V, O'Dushlaine C, Teslovich TM, Benotti PN, Mirshahi T, Gottesman O, Van Hout CV, Murray MF, Mahajan A, Nielsen JB, Fritsche L, Wulff AB, Gudbjartsson DF, Sjögren M, Emdin CA, Scott RA, Lee WJ, Small A, Kwee LC, Dwivedi OP, Prasad RB, Bruse S, Lopez AE, Penn J, Marcketta A, Leader JB, Still CD, Kirchner HL, Mirshahi UL, Wardeh AH, Hartle CM, Habegger L, Fetterolf SN, Tusie-Luna T, Morris AP, Holm H, Steinthorsdottir V, Sulem P, Thorsteinsdottir U, Rotter JI, Chuang LM, Damrauer S, Birtwell D, Brummett CM, Khera AV, Natarajan P, Orho-Melander M, Flannick J, Lotta LA, Willer CJ, Holmen OL, Ritchie MD, Ledbetter DH, Murphy AJ, Borecki IB, Reid JG, Overton JD, Hansson O, Groop L, Shah SH, Kraus WE, Rader DJ, Chen YI, Hveem K, Wareham NJ, Kathiresan S, Melander O, Stefansson K, Nordestgaard BG, Tybjærg-Hansen A, Abecasis GR, Altshuler D, Florez JC, Boehnke M, McCarthy MI, Yancopoulos GD, Carey DJ, Shuldiner AR, Baras A, Dewey FE, Gromada J.

Nat Commun. 2018 Jun 13;9(1):2252. doi: 10.1038/s41467-018-04611-z.

14.

Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells.

Taneera J, Prasad RB, Dhaiban S, Mohammed AK, Haataja L, Arvan P, Hamad M, Groop L, Wollheim CB.

Mol Cell Endocrinol. 2018 Sep 5;472:10-17. doi: 10.1016/j.mce.2018.06.003. Epub 2018 Jun 8.

15.

Novel diabetes subgroups - Authors' reply.

Ahlqvist E, Prasad RB, Tuomi T, Rosengren A, Groop L.

Lancet Diabetes Endocrinol. 2018 Jun;6(6):440-441. doi: 10.1016/S2213-8587(18)30139-6. No abstract available.

PMID:
29803264
16.

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland.

Martin AR, Karczewski KJ, Kerminen S, Kurki MI, Sarin AP, Artomov M, Eriksson JG, Esko T, Genovese G, Havulinna AS, Kaprio J, Konradi A, Korányi L, Kostareva A, Männikkö M, Metspalu A, Perola M, Prasad RB, Raitakari O, Rotar O, Salomaa V, Groop L, Palotie A, Neale BM, Ripatti S, Pirinen M, Daly MJ.

Am J Hum Genet. 2018 May 3;102(5):760-775. doi: 10.1016/j.ajhg.2018.03.003. Epub 2018 Apr 26.

17.

Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables.

Ahlqvist E, Storm P, Käräjämäki A, Martinell M, Dorkhan M, Carlsson A, Vikman P, Prasad RB, Aly DM, Almgren P, Wessman Y, Shaat N, Spégel P, Mulder H, Lindholm E, Melander O, Hansson O, Malmqvist U, Lernmark Å, Lahti K, Forsén T, Tuomi T, Rosengren AH, Groop L.

Lancet Diabetes Endocrinol. 2018 May;6(5):361-369. doi: 10.1016/S2213-8587(18)30051-2. Epub 2018 Mar 5.

PMID:
29503172
18.

Nutritionally enriched 1,3-diacylglycerol-rich oil: Low calorie fat with hypolipidemic effects in rats.

Prabhavathi Devi BLA, Gangadhar KN, Prasad RBN, Sugasini D, Rao YPC, Lokesh BR.

Food Chem. 2018 May 15;248:210-216. doi: 10.1016/j.foodchem.2017.12.066. Epub 2017 Dec 19.

PMID:
29329846
19.

Role of Brachial Artery Ligation in Management of Prosthetic Arteriovenous Graft Infections.

Chandrashekar AR, Hoskatti CR, Desai SC, Prasad RB.

Ann Vasc Surg. 2018 Apr;48:75-78. doi: 10.1016/j.avsg.2017.10.013. Epub 2017 Dec 5.

PMID:
29217449
20.

Role of osteopontin and its regulation in pancreatic islet.

Cai M, Bompada P, Salehi A, Acosta JR, Prasad RB, Atac D, Laakso M, Groop L, De Marinis Y.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1426-1431. doi: 10.1016/j.bbrc.2017.11.147. Epub 2017 Nov 24.

PMID:
29180017
21.

Genetic determinants of circulating GIP and GLP-1 concentrations.

Almgren P, Lindqvist A, Krus U, Hakaste L, Ottosson-Laakso E, Asplund O, Sonestedt E, Prasad RB, Laurila E, Orho-Melander M, Melander O, Tuomi T, Holst JJ, Nilsson PM, Wierup N, Groop L, Ahlqvist E.

JCI Insight. 2017 Nov 2;2(21). pii: 93306. doi: 10.1172/jci.insight.93306.

22.

Glucose-Induced Changes in Gene Expression in Human Pancreatic Islets: Causes or Consequences of Chronic Hyperglycemia.

Ottosson-Laakso E, Krus U, Storm P, Prasad RB, Oskolkov N, Ahlqvist E, Fadista J, Hansson O, Groop L, Vikman P.

Diabetes. 2017 Dec;66(12):3013-3028. doi: 10.2337/db17-0311. Epub 2017 Sep 7.

23.

Insulin secretion and action in North Indian women during pregnancy.

Arora GP, Almgren P, Thaman RG, Pal A, Groop L, Vaag A, Prasad RB, Brøns C.

Diabet Med. 2017 Oct;34(10):1477-1482. doi: 10.1111/dme.13428. Epub 2017 Aug 17.

PMID:
28731584
24.

Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides.

Vudhgiri S, Koude D, Veeragoni DK, Misra S, Prasad RBN, Jala RCR.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3370-3373. doi: 10.1016/j.bmcl.2017.06.004. Epub 2017 Jun 3.

PMID:
28615134
25.

Comparative Evaluation of the Lipid Profile in the Serum of Patients with Type II Diabetes Mellitus and Healthy Individuals with Periodontitis.

Thomas B, Prasad RB, Shetty S, Vishakh R.

Contemp Clin Dent. 2017 Jan-Mar;8(1):96-101. doi: 10.4103/ccd.ccd_1160_16.

26.

MECHANISMS IN ENDOCRINOLOGY: Epigenetic modifications and gestational diabetes: a systematic review of published literature.

Moen GH, Sommer C, Prasad RB, Sletner L, Groop L, Qvigstad E, Birkeland KI.

Eur J Endocrinol. 2017 May;176(5):R247-R267. doi: 10.1530/EJE-16-1017. Epub 2017 Feb 23. Review.

PMID:
28232369
27.

Synthesis and evaluation of anti-oxidant and cytotoxic activities of novel 10-undecenoic acid methyl ester based lipoconjugates of phenolic acids.

Narra N, Kaki SS, Prasad RB, Misra S, Dhevendar K, Kontham V, Korlipara PV.

Beilstein J Org Chem. 2017 Jan 4;13:26-32. doi: 10.3762/bjoc.13.4. eCollection 2017.

28.

An anti-oxidant, α-lipoic acid conjugated oleoyl-sn-phosphatidylcholineas a helper lipid in cationic liposomal formulations.

Dharmalingam P, Marrapu B, Voshavar C, Nadella R, Rangasami VK, Shaji RV, Abbas S, Prasad RBN, Kaki SS, Marepally S.

Colloids Surf B Biointerfaces. 2017 Apr 1;152:133-142. doi: 10.1016/j.colsurfb.2017.01.013. Epub 2017 Jan 10.

PMID:
28103530
29.

Synthesis and in vitro antioxidant and antimicrobial studies of novel structured phosphatidylcholines with phenolic acids.

Balakrishna M, Kaki SS, Karuna MSL, Sarada S, Kumar CG, Prasad RBN.

Food Chem. 2017 Apr 15;221:664-672. doi: 10.1016/j.foodchem.2016.11.121. Epub 2016 Nov 25.

PMID:
27979256
30.

Effects of boiling and roasting on proximate composition, lipid oxidation, fatty acid profile and mineral content of two sesame varieties commercialized and consumed in Far-North Region of Cameroon.

Tenyang N, Ponka R, Tiencheu B, Djikeng FT, Azmeera T, Karuna MSL, Prasad RBN, Womeni HM.

Food Chem. 2017 Apr 15;221:1308-1316. doi: 10.1016/j.foodchem.2016.11.025. Epub 2016 Nov 8.

PMID:
27979094
31.

Synthesis of Novel Fatty Substituted 4-methyl-2HChromen-2-one via Cross Metathesis: Potential Antioxidants and Chemotherapeutic Agents.

Yelchuri V, Prasad RB, Karuna MS, Poornachandra Y, Kumar CG.

J Oleo Sci. 2016 Dec 1;65(12):1023-1031. Epub 2016 Nov 9.

32.

Valorization of soursop flowers (Annona muricata L.) as potent source of natural antioxidants for stabilization of palm olein during accelerated storage.

Womeni HM, Tonfack Djikeng F, Iruku NS, Karuna MS, Prasad RB, Linder M.

Food Sci Nutr. 2016 Feb 16;4(6):802-810. eCollection 2016 Nov.

33.

Synthesis and biological evaluation of ricinoleic acid-based lipoamino acid derivatives.

Mohini Y, Prasad RB, Karuna MS, Poornachandra Y, Ganesh Kumar C.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5198-5202. doi: 10.1016/j.bmcl.2016.09.063. Epub 2016 Sep 28.

PMID:
27707604
34.

Single-Cell Sequencing of Human Pancreatic Islets-New Kids on the Block.

Prasad RB, Groop L.

Cell Metab. 2016 Oct 11;24(4):523-524. doi: 10.1016/j.cmet.2016.09.012.

35.

Total synthesis and in vitro bioevaluation of clavaminols A, C, H & deacetyl clavaminol H as potential chemotherapeutic and antibiofilm agents.

Vijai Kumar Reddy T, Jyotsna A, Prabhavathi Devi BL, Prasad RB, Poornachandra Y, Ganesh Kumar C.

Eur J Med Chem. 2016 Sep 14;120:86-96. doi: 10.1016/j.ejmech.2016.04.073. Epub 2016 May 6.

PMID:
27187861
36.

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.

Prasad RB, Lessmark A, Almgren P, Kovacs G, Hansson O, Oskolkov N, Vitai M, Ladenvall C, Kovacs P, Fadista J, Lachmann M, Zhou Y, Sonestedt E, Poon W, Wollheim CB, Orho-Melander M, Stumvoll M, Tuomi T, Pääbo S, Koranyi L, Groop L.

Diabetologia. 2016 Aug;59(8):1702-13. doi: 10.1007/s00125-016-3973-9. Epub 2016 May 7.

PMID:
27155871
37.

Design, synthesis and in vitro biological evaluation of short-chain C12-sphinganine and its 1,2,3-triazole analogs as potential antimicrobial and anti-biofilm agents.

Vijai Kumar Reddy T, Jyotsna A, Prabhavathi Devi BL, Prasad RB, Poornachandra Y, Ganesh Kumar C.

Eur J Med Chem. 2016 Aug 8;118:98-106. doi: 10.1016/j.ejmech.2016.04.020. Epub 2016 Apr 9.

PMID:
27128176
38.

Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk.

Lyssenko V, Groop L, Prasad RB.

Rev Diabet Stud. 2015 Fall-Winter;12(3-4):233-42. doi: 10.1900/RDS.2015.12.233. Epub 2016 Feb 10. Review.

39.

PE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulence.

Singh P, Rao RN, Reddy JR, Prasad RB, Kotturu SK, Ghosh S, Mukhopadhyay S.

Sci Rep. 2016 Feb 23;6:21624. doi: 10.1038/srep21624.

40.

Synthesis of dihydrosterculic acid-based monoglucosyl diacylglycerol and its analogues and their biological evaluation.

Srikanth V, Prasad RB, Poornachandra Y, Phani Babu VS, Ganesh Kumar C, Jagadeesh B, Jala RC.

Eur J Med Chem. 2016 Feb 15;109:134-45. doi: 10.1016/j.ejmech.2015.12.048. Epub 2015 Dec 31.

PMID:
26774921
41.

Synthesis of novel ethyl 1-ethyl-6-fluoro-7-(fatty amido)-1,4-dihydro-4-oxoquinoline-3-carboxylate derivatives and their biological evaluation.

Venepally V, Prasad RBN, Poornachandra Y, Kumar CG, Jala RCR.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):613-617. doi: 10.1016/j.bmcl.2015.11.063. Epub 2015 Nov 29.

PMID:
26646219
42.

Stage-Specific Fatty Acid Fluxes Play a Regulatory Role in Glycerolipid Metabolism during Seed Development in Jatropha curcas L.

Chaitanya BS, Kumar S, Kaki SS, Balakrishna M, Karuna MS, Prasad RB, Sastry PS, Reddy AR.

J Agric Food Chem. 2015 Dec 23;63(50):10811-21. doi: 10.1021/acs.jafc.5b04824. Epub 2015 Dec 15.

PMID:
26628196
43.

Synthesis and biological evaluation of novel lipoamino acid derivatives.

Kaki SS, Arukali S, Korlipara PV, Prasad RB, Yedla P, Ganesh Kumar C.

Bioorg Med Chem Lett. 2016 Jan 1;26(1):209-12. doi: 10.1016/j.bmcl.2015.10.086. Epub 2015 Nov 2.

PMID:
26586599
44.

A Novel Methodology for the Synthesis of Acyloxy Castor Polyol Esters: Low Pour Point Lubricant Base Stocks.

Kamalakar K, Mahesh G, Prasad RB, Karuna MS.

J Oleo Sci. 2015;64(12):1283-95. doi: 10.5650/jos.ess15133. Epub 2015 Nov 19.

45.

Lipase catalyzed interesterification of rice bran oil with hydrogenated cottonseed oil to produce trans free fat.

Neeharika TS, Rallabandi R, Ragini Y, Kaki SS, Rani KN, Prasad RB.

J Food Sci Technol. 2015 Aug;52(8):4905-14. doi: 10.1007/s13197-014-1563-8. Epub 2014 Sep 23.

46.

Prevalence and risk factors of gestational diabetes in Punjab, North India: results from a population screening program.

Arora GP, Thaman RG, Prasad RB, Almgren P, Brøns C, Groop LC, Vaag AA.

Eur J Endocrinol. 2015 Aug;173(2):257-67. doi: 10.1530/EJE-14-0428. Epub 2015 May 26.

PMID:
26012589
47.

Synthesis and Anti-microbial Activity of Novel Phosphatidylethanolamine-N-amino Acid Derivatives.

Vijeetha T, Balakrishna M, Karuna MS, Surya Koppeswara Rao BV, Prasad RB, Kumar KP, Surya Narayana Murthy U.

J Oleo Sci. 2015;64(7):705-12. doi: 10.5650/jos.ess15063. Epub 2015 May 21.

48.

Hydrolysis of biomass using a reusable solid carbon acid catalyst and fermentation of the catalytic hydrolysate to ethanol.

Goswami M, Meena S, Navatha S, Prasanna Rani KN, Pandey A, Sukumaran RK, Prasad RB, Prabhavathi Devi BL.

Bioresour Technol. 2015;188:99-102. doi: 10.1016/j.biortech.2015.03.012. Epub 2015 Mar 7.

PMID:
25777067
49.

Genetics of type 2 diabetes-pitfalls and possibilities.

Prasad RB, Groop L.

Genes (Basel). 2015 Mar 12;6(1):87-123. doi: 10.3390/genes6010087. Review.

50.

Novel acyloxy derivatives of branched mono- and polyol esters of sal fat: multiviscosity grade lubricant base stocks.

Kamalakar K, Sai Manoj GN, Prasad RB, Karuna MS.

J Agric Food Chem. 2014 Dec 10;62(49):11980-7. doi: 10.1021/jf504700m. Epub 2014 Nov 26.

PMID:
25416127

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