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Items: 1 to 50 of 143


Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories.

Criglar JM, Anish R, Hu L, Crawford SE, Sankaran B, Prasad BVV, Estes MK.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E12015-E12023. doi: 10.1073/pnas.1717944115. Epub 2018 Dec 3.


Differential active site requirements for NDM-1 β-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics.

Sun Z, Hu L, Sankaran B, Prasad BVV, Palzkill T.

Nat Commun. 2018 Oct 30;9(1):4524. doi: 10.1038/s41467-018-06839-1.


Immunodiagnostic potential of Wuchereria bancrofti L1 antigen-based filarial immunoglobulin G4 detection assay.

Prasad BVS, Khatri V, Yadav PS, Chandra MS, Lakshmi DV, Goswami K.

Trans R Soc Trop Med Hyg. 2019 Jan 1;113(1):36-43. doi: 10.1093/trstmh/try110.


Synergistic effects of functionally distinct substitutions in β-lactamase variants shed light on the evolution of bacterial drug resistance.

Patel MP, Hu L, Brown CA, Sun Z, Adamski CJ, Stojanoski V, Sankaran B, Prasad BVV, Palzkill T.

J Biol Chem. 2018 Nov 16;293(46):17971-17984. doi: 10.1074/jbc.RA118.003792. Epub 2018 Oct 1.


Glycan recognition in globally dominant human rotaviruses.

Hu L, Sankaran B, Laucirica DR, Patil K, Salmen W, Ferreon ACM, Tsoi PS, Lasanajak Y, Smith DF, Ramani S, Atmar RL, Estes MK, Ferreon JC, Prasad BVV.

Nat Commun. 2018 Jul 6;9(1):2631. doi: 10.1038/s41467-018-05098-4.


Reovirus Nonstructural Protein σNS Acts as an RNA Stability Factor Promoting Viral Genome Replication.

Zamora PF, Hu L, Knowlton JJ, Lahr RM, Moreno RA, Berman AJ, Prasad BVV, Dermody TS.

J Virol. 2018 Jul 17;92(15). pii: e00563-18. doi: 10.1128/JVI.00563-18. Print 2018 Aug 1.


RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution.

Venkataraman S, Prasad BVLS, Selvarajan R.

Viruses. 2018 Feb 10;10(2). pii: E76. doi: 10.3390/v10020076. Review.


The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.

Patel MP, Hu L, Stojanoski V, Sankaran B, Prasad BVV, Palzkill T.

Biochemistry. 2017 Jul 11;56(27):3443-3453. doi: 10.1021/acs.biochem.7b00176. Epub 2017 Jun 27.


A Case-control Study for the Assessment of Correlation of Denture-related Sores and Oral Cancer Risk.

Jain P, Jain M, Prasad BV, Kakatkar GS, Patel M, Khan J.

J Contemp Dent Pract. 2016 Nov 1;17(11):930-933.


Expression of Myofibroblasts in Oral Squamous Cell Carcinoma: An Immunohistochemical Study.

Prasad BV, Kakatkar GS, Jain P, Jain M, Patel M, Khan J.

J Contemp Dent Pract. 2016 Oct 1;17(10):857-860.


Bundle branch reentry: A rare mechanism of ventricular tachycardia in endomyocardial fibrosis, without ventricular dilation.

Prabhu MA, Prasad BV, Thajudeen A, Namboodiri N.

Indian Heart J. 2016 Sep;68 Suppl 2:S198-S201. doi: 10.1016/j.ihj.2016.02.005. Epub 2016 Apr 14.


Structure of the catalytic domain of the colistin resistance enzyme MCR-1.

Stojanoski V, Sankaran B, Prasad BV, Poirel L, Nordmann P, Palzkill T.

BMC Biol. 2016 Sep 21;14(1):81.


Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody.

Shanker S, Czakó R, Sapparapu G, Alvarado G, Viskovska M, Sankaran B, Atmar RL, Crowe JE Jr, Estes MK, Prasad BV.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5830-E5837. Epub 2016 Sep 19.


Correction for Hesse et al., Serological Responses to a Norovirus Nonstructural Fusion Protein after Vaccination and Infection.

Hesse S, Neill FH, Estes MK, Shanker S, Prasad BV, Ferreira J, Atmar RL.

Clin Vaccine Immunol. 2016 Aug 5;23(8):735. doi: 10.1128/CVI.00260-16. Print 2016 Aug. No abstract available.


Acute outcome of treating patients admitted with electrical storm in a tertiary care centre.

Prabhu MA, Namboodiri N, Prasad Bv S, Abhilash SP, Thajudeen A, Ajith KV.

Indian Pacing Electrophysiol J. 2016 Mar 29;15(6):286-90. doi: 10.1016/j.ipej.2016.03.002. eCollection 2015 Nov-Dec.


Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding.

Sapparapu G, Czakó R, Alvarado G, Shanker S, Prasad BV, Atmar RL, Estes MK, Crowe JE Jr.

PLoS Pathog. 2016 Jun 29;12(6):e1005719. doi: 10.1371/journal.ppat.1005719. eCollection 2016 Jun.


Strain-Specific Virolysis Patterns of Human Noroviruses in Response to Alcohols.

Park GW, Collins N, Barclay L, Hu L, Prasad BV, Lopman BA, Vinjé J.

PLoS One. 2016 Jun 23;11(6):e0157787. doi: 10.1371/journal.pone.0157787. eCollection 2016.


Antiviral targets of human noroviruses.

Prasad BV, Shanker S, Muhaxhiri Z, Deng L, Choi JM, Estes MK, Song Y, Palzkill T, Atmar RL.

Curr Opin Virol. 2016 Jun;18:117-25. doi: 10.1016/j.coviro.2016.06.002. Epub 2016 Jun 17. Review.


Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine β-Lactamases by Relieving Steric Strain.

Stojanoski V, Adamski CJ, Hu L, Mehta SC, Sankaran B, Zwart P, Prasad BV, Palzkill T.

Biochemistry. 2016 May 3;55(17):2479-90. doi: 10.1021/acs.biochem.6b00056. Epub 2016 Apr 22.


Multiple oligomeric structures of a bacterial small heat shock protein.

Mani N, Bhandari S, Moreno R, Hu L, Prasad BVV, Suguna K.

Sci Rep. 2016 Apr 7;6:24019. doi: 10.1038/srep24019.


Serological Responses to a Norovirus Nonstructural Fusion Protein after Vaccination and Infection.

Hesse S, Neill FH, Estes MK, Shanker S, Prasad BV, Ferreira J, Atmar RL.

Clin Vaccine Immunol. 2015 Dec 9;23(2):181-3. doi: 10.1128/CVI.00595-15. Print 2016 Feb. Erratum in: Clin Vaccine Immunol. 2016 Aug;23(8):735.


Quelling an innate response to dsRNA.

Ogden KM, Prasad BV.

Oncotarget. 2015 Oct 6;6(30):28535-6. doi: 10.18632/oncotarget.5110. No abstract available.


Structural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by Halogens.

Stojanoski V, Chow DC, Fryszczyn B, Hu L, Nordmann P, Poirel L, Sankaran B, Prasad BV, Palzkill T.

Biochemistry. 2015 Jun 2;54(21):3370-80. doi: 10.1021/acs.biochem.5b00298. Epub 2015 May 14.


Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist.

Ogden KM, Hu L, Jha BK, Sankaran B, Weiss SR, Silverman RH, Patton JT, Prasad BV.

J Virol. 2015 Jul;89(13):6633-45.


A triple mutant in the Ω-loop of TEM-1 β-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis.

Stojanoski V, Chow DC, Hu L, Sankaran B, Gilbert HF, Prasad BV, Palzkill T.

J Biol Chem. 2015 Apr 17;290(16):10382-94. doi: 10.1074/jbc.M114.633438. Epub 2015 Feb 20.


Molecular basis for the catalytic specificity of the CTX-M extended-spectrum β-lactamases.

Adamski CJ, Cardenas AM, Brown NG, Horton LB, Sankaran B, Prasad BV, Gilbert HF, Palzkill T.

Biochemistry. 2015 Jan 20;54(2):447-57. doi: 10.1021/bi501195g. Epub 2014 Dec 24.


Structural plasticity of the coiled-coil domain of rotavirus NSP4.

Sastri NP, Viskovska M, Hyser JM, Tanner MR, Horton LB, Sankaran B, Prasad BV, Estes MK.

J Virol. 2014 Dec;88(23):13602-12. doi: 10.1128/JVI.02227-14. Epub 2014 Sep 17.


Probing the sites of interactions of rotaviral proteins involved in replication.

Viskovska M, Anish R, Hu L, Chow DC, Hurwitz AM, Brown NG, Palzkill T, Estes MK, Prasad BV.

J Virol. 2014 Nov;88(21):12866-81. doi: 10.1128/JVI.02251-14. Epub 2014 Aug 27.


Human milk contains novel glycans that are potential decoy receptors for neonatal rotaviruses.

Yu Y, Lasanajak Y, Song X, Hu L, Ramani S, Mickum ML, Ashline DJ, Prasad BV, Estes MK, Reinhold VN, Cummings RD, Smith DF.

Mol Cell Proteomics. 2014 Nov;13(11):2944-60. doi: 10.1074/mcp.M114.039875. Epub 2014 Jul 21.


Development of a Gaussia luciferase-based human norovirus protease reporter system: cell type-specific profile of Norwalk virus protease precursors and evaluation of inhibitors.

Qu L, Vongpunsawad S, Atmar RL, Prasad BV, Estes MK.

J Virol. 2014 Sep;88(18):10312-26. doi: 10.1128/JVI.01111-14. Epub 2014 Jul 9.


Structural analysis of determinants of histo-blood group antigen binding specificity in genogroup I noroviruses.

Shanker S, Czako R, Sankaran B, Atmar RL, Estes MK, Prasad BV.

J Virol. 2014 Jun;88(11):6168-80. doi: 10.1128/JVI.00201-14. Epub 2014 Mar 19.


The influenza A virus protein NS1 displays structural polymorphism.

Carrillo B, Choi JM, Bornholdt ZA, Sankaran B, Rice AP, Prasad BV.

J Virol. 2014 Apr;88(8):4113-22. doi: 10.1128/JVI.03692-13. Epub 2014 Jan 29.


Synthesis, Activity and Structure-Activity Relationship of Noroviral Protease Inhibitors.

Deng L, Muhaxhiri Z, Estes MK, Palzkill T, Prasad BV, Song Y.

Medchemcomm. 2013 Oct;4(10). doi: 10.1039/C3MD00219E.


A novel form of rotavirus NSP2 and phosphorylation-dependent NSP2-NSP5 interactions are associated with viroplasm assembly.

Criglar JM, Hu L, Crawford SE, Hyser JM, Broughman JR, Prasad BV, Estes MK.

J Virol. 2014 Jan;88(2):786-98. doi: 10.1128/JVI.03022-13. Epub 2013 Nov 6.


A study on interleukin -1β and lipid profile as markers of cardiovascular risk in rheumatoid arthritis.

Kumar D V, Prasad BV, Vishwanth HL, Kamath V.

J Clin Diagn Res. 2013 Jul;7(7):1298-302. doi: 10.7860/JCDR/2013/6110.3122. Epub 2013 May 31.


Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase.

Zheng B, Yao Y, Liu Z, Deng L, Anglin JL, Jiang H, Prasad BV, Song Y.

ACS Med Chem Lett. 2013 Jun 13;4(6):542-546.


The VP8* domain of neonatal rotavirus strain G10P[11] binds to type II precursor glycans.

Ramani S, Cortes-Penfield NW, Hu L, Crawford SE, Czako R, Smith DF, Kang G, Ramig RF, Le Pendu J, Prasad BV, Estes MK.

J Virol. 2013 Jul;87(13):7255-64. doi: 10.1128/JVI.03518-12. Epub 2013 Apr 24.


The computational analysis of human testis transcriptome reveals closer ties to pluripotency.

Anand M, Prasad BV.

J Hum Reprod Sci. 2012 Sep;5(3):266-73. doi: 10.4103/0974-1208.106339.


Structural basis of substrate specificity and protease inhibition in Norwalk virus.

Muhaxhiri Z, Deng L, Shanker S, Sankaran B, Estes MK, Palzkill T, Song Y, Prasad BV.

J Virol. 2013 Apr;87(8):4281-92. doi: 10.1128/JVI.02869-12. Epub 2013 Jan 30.


Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ).

Rahman GM, Shanker S, Lewin NE, Kedei N, Hill CS, Prasad BV, Blumberg PM, Das J.

Biochem J. 2013 Apr 1;451(1):33-44. doi: 10.1042/BJ20121307. Erratum in: Biochem J. 2013 Jul 1;453(1):153.


Antibody responses to norovirus genogroup GI.1 and GII.4 proteases in volunteers administered Norwalk virus.

Ajami NJ, Barry MA, Carrillo B, Muhaxhiri Z, Neill FH, Prasad BV, Opekun AR, Gilger MA, Graham DY, Atmar RL, Estes MK.

Clin Vaccine Immunol. 2012 Dec;19(12):1980-3. doi: 10.1128/CVI.00411-12. Epub 2012 Oct 3.


Menopause versus aging: The predictor of obesity and metabolic aberrations among menopausal women of Karnataka, South India.

Dasgupta S, Salman M, Lokesh S, Xaviour D, Saheb SY, Prasad BV, Sarkar B.

J Midlife Health. 2012 Jan;3(1):24-30. doi: 10.4103/0976-7800.98814.


Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.

Hu L, Chow DC, Patton JT, Palzkill T, Estes MK, Prasad BV.

J Virol. 2012 Oct;86(19):10547-57. doi: 10.1128/JVI.01201-12. Epub 2012 Jul 18.


Rotavirus non-structural proteins: structure and function.

Hu L, Crawford SE, Hyser JM, Estes MK, Prasad BV.

Curr Opin Virol. 2012 Aug;2(4):380-8. doi: 10.1016/j.coviro.2012.06.003. Epub 2012 Jul 11. Review.


Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen.

Hu L, Crawford SE, Czako R, Cortes-Penfield NW, Smith DF, Le Pendu J, Estes MK, Prasad BV.

Nature. 2012 Apr 15;485(7397):256-9. doi: 10.1038/nature10996.


Principles of virus structural organization.

Prasad BV, Schmid MF.

Adv Exp Med Biol. 2012;726:17-47. doi: 10.1007/978-1-4614-0980-9_3. Review.


Prestress strengthens the shell of Norwalk virus nanoparticles.

Baclayon M, Shoemaker GK, Uetrecht C, Crawford SE, Estes MK, Prasad BV, Heck AJ, Wuite GJ, Roos WH.

Nano Lett. 2011 Nov 9;11(11):4865-9. doi: 10.1021/nl202699r. Epub 2011 Oct 10.


Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies.

Yao Y, Chen P, Diao J, Cheng G, Deng L, Anglin JL, Prasad BV, Song Y.

J Am Chem Soc. 2011 Oct 26;133(42):16746-9. doi: 10.1021/ja206312b. Epub 2011 Oct 4. Erratum in: J Am Chem Soc. 2012 Oct 24;134(42):17834.


Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases.

Brown NG, Chow DC, Sankaran B, Zwart P, Prasad BV, Palzkill T.

J Biol Chem. 2011 Sep 16;286(37):32723-35. doi: 10.1074/jbc.M111.265058. Epub 2011 Jul 20.


Structural analysis of histo-blood group antigen binding specificity in a norovirus GII.4 epidemic variant: implications for epochal evolution.

Shanker S, Choi JM, Sankaran B, Atmar RL, Estes MK, Prasad BV.

J Virol. 2011 Sep;85(17):8635-45. doi: 10.1128/JVI.00848-11. Epub 2011 Jun 29.

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