Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 112

1.

How a four-year-old boy connects healthcare, biomedical research and undergraduate education.

Drost RH, Dictus WJAG, Prakken BJ, Bovenschen N.

Nat Biotechnol. 2019 Sep;37(9):1092-1095. doi: 10.1038/s41587-019-0245-5. No abstract available.

PMID:
31485047
2.

Preventing Translational Scientists From Extinction: The Long-Term Impact of a Personalized Training Program in Translational Medicine on the Careers of Translational Scientists.

Weggemans MM, van der Schaaf M, Kluijtmans M, Hafler JP, Rosenblum ND, Prakken BJ.

Front Med (Lausanne). 2018 Nov 9;5:298. doi: 10.3389/fmed.2018.00298. eCollection 2018.

3.

Children and young people get rheumatic disease too.

Egert Y, Egert T, Costello W, Prakken BJ, Smith EMD, Wulffraat NM.

Lancet Child Adolesc Health. 2019 Jan;3(1):8-9. doi: 10.1016/S2352-4642(18)30374-2. Epub 2018 Nov 23. No abstract available.

PMID:
30473439
4.

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation.

Petrelli A, Mijnheer G, Hoytema van Konijnenburg DP, van der Wal MM, Giovannone B, Mocholi E, Vazirpanah N, Broen JC, Hijnen D, Oldenburg B, Coffer PJ, Vastert SJ, Prakken BJ, Spierings E, Pandit A, Mokry M, van Wijk F.

J Clin Invest. 2018 Oct 1;128(10):4669-4681. doi: 10.1172/JCI96107. Epub 2018 Aug 2.

5.

Monocyte gene expression in childhood obesity is associated with obesity and complexity of atherosclerosis in adults.

Keustermans GC, Kofink D, Eikendal A, de Jager W, Meerding J, Nuboer R, Waltenberger J, Kraaijeveld AO, Jukema JW, Sels JW, Garssen J, Prakken BJ, Asselbergs FW, Kalkhoven E, Hoefer IE, Pasterkamp G, Schipper HS.

Sci Rep. 2017 Dec 4;7(1):16826. doi: 10.1038/s41598-017-17195-3.

6.

Effect of anticoagulants on 162 circulating immune related proteins in healthy subjects.

Scholman RC, Giovannone B, Hiddingh S, Meerding JM, Malvar Fernandez B, van Dijk MEA, Tempelman MJ, Prakken BJ, de Jager W.

Cytokine. 2018 Jun;106:114-124. doi: 10.1016/j.cyto.2017.10.021. Epub 2017 Oct 28.

7.

Recommendations for collaborative paediatric research including biobanking in Europe: a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative.

Kuemmerle-Deschner JB, Hansmann S, Wulffraat NM, Vastert SJ, Hens K, Anton J, Avcin T, Martini A, Koné-Paut I, Uziel Y, Ravelli A, Wouters C, Shaw D, Özen S, Eikelberg A, Prakken BJ, Ruperto N, Horneff G, Constantin T, Beresford MW, Sikken M, Foster HE, Haug I, Schuller S, Jägle C, Benseler SM.

Ann Rheum Dis. 2018 Mar;77(3):319-327. doi: 10.1136/annrheumdis-2017-211904. Epub 2017 Oct 11. Review.

PMID:
29021237
8.

Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders.

Te Velde AA, Bezema T, van Kampen AH, Kraneveld AD, 't Hart BA, van Middendorp H, Hack EC, van Montfrans JM, Belzer C, Jans-Beken L, Pieters RH, Knipping K, Huber M, Boots AM, Garssen J, Radstake TR, Evers AW, Prakken BJ, Joosten I.

Front Immunol. 2016 Dec 12;7:587. doi: 10.3389/fimmu.2016.00587. eCollection 2016.

9.

Developing translational medicine professionals: the Marie Skłodowska-Curie action model.

Petrelli A, Prakken BJ, Rosenblum ND; EUtrain fellows.

J Transl Med. 2016 Nov 29;14(1):329.

10.

Understanding inflammation in juvenile idiopathic arthritis: How immune biomarkers guide clinical strategies in the systemic onset subtype.

Swart JF, de Roock S, Prakken BJ.

Eur J Immunol. 2016 Sep;46(9):2068-77. doi: 10.1002/eji.201546092. Review.

11.

Autoimmune disease-associated gene expression is reduced by BET-inhibition.

Peeters JG, Vervoort SJ, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Mokry M, van Loosdregt J.

Genom Data. 2015 Nov 7;7:14-7. doi: 10.1016/j.gdata.2015.11.004. eCollection 2016 Mar.

12.

Neonatal thymectomy reveals differentiation and plasticity within human naive T cells.

van den Broek T, Delemarre EM, Janssen WJ, Nievelstein RA, Broen JC, Tesselaar K, Borghans JA, Nieuwenhuis EE, Prakken BJ, Mokry M, Jansen NJ, van Wijk F.

J Clin Invest. 2016 Mar 1;126(3):1126-36. doi: 10.1172/JCI84997. Epub 2016 Feb 22.

13.

Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.

Delemarre EM, van den Broek T, Mijnheer G, Meerding J, Wehrens EJ, Olek S, Boes M, van Herwijnen MJ, Broere F, van Royen A, Wulffraat NM, Prakken BJ, Spierings E, van Wijk F.

Blood. 2016 Jan 7;127(1):91-101. doi: 10.1182/blood-2015-06-649145. Epub 2015 Oct 19.

PMID:
26480932
14.

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression.

Peeters JG, Vervoort SJ, Tan SC, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Creyghton MP, Coffer PJ, Mokry M, van Loosdregt J.

Cell Rep. 2015 Sep 29;12(12):1986-96. doi: 10.1016/j.celrep.2015.08.046. Epub 2015 Sep 17.

15.

Self-Sustained Resistance to Suppression of CD8+ Teff Cells at the Site of Autoimmune Inflammation Can Be Reversed by Tumor Necrosis Factor and Interferon-γ Blockade.

Petrelli A, Wehrens EJ, Scholman RC, Prakken BJ, Vastert SJ, van Wijk F.

Arthritis Rheumatol. 2016 Jan;68(1):229-36. doi: 10.1002/art.39418.

16.

Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis.

Bulatović Ćalasan M, Vastert SJ, Scholman RC, Verweij F, Klein M, Wulffraat NM, Prakken BJ, van Wijk F.

Rheumatology (Oxford). 2015 Sep;54(9):1724-34. doi: 10.1093/rheumatology/kev101. Epub 2015 Apr 14.

PMID:
25877908
17.

Paediatric rheumatic disease: Diagnosing macrophage activation syndrome in systemic JIA.

Vastert SJ, Prakken BJ.

Nat Rev Rheumatol. 2014 Nov;10(11):640-2. doi: 10.1038/nrrheum.2014.143. Epub 2014 Sep 9.

PMID:
25201384
18.

Redefining Strategies to Introduce Tolerance-Inducing Cellular Therapy in Human beings to Combat Autoimmunity and Transplantation Reactions.

Ten Brinke A, Joosten I, van Ham SM, van Kooten C, Prakken BJ.

Front Immunol. 2014 Aug 15;5:392. doi: 10.3389/fimmu.2014.00392. eCollection 2014. Review.

19.

Increased presence of FOXP3+ regulatory T cells in inflamed muscle of patients with active juvenile dermatomyositis compared to peripheral blood.

Vercoulen Y, Bellutti Enders F, Meerding J, Plantinga M, Elst EF, Varsani H, van Schieveen C, Bakker MH, Klein M, Scholman RC, Spliet W, Ricotti V, Koenen HJ, de Weger RA, Wedderburn LR, van Royen-Kerkhof A, Prakken BJ.

PLoS One. 2014 Aug 26;9(8):e105353. doi: 10.1371/journal.pone.0105353. eCollection 2014.

20.

Effectiveness of first-line treatment with recombinant interleukin-1 receptor antagonist in steroid-naive patients with new-onset systemic juvenile idiopathic arthritis: results of a prospective cohort study.

Vastert SJ, de Jager W, Noordman BJ, Holzinger D, Kuis W, Prakken BJ, Wulffraat NM.

Arthritis Rheumatol. 2014 Apr;66(4):1034-43. doi: 10.1002/art.38296.

21.

Correlation of CXCL10, tumor necrosis factor receptor type II, and galectin 9 with disease activity in juvenile dermatomyositis.

Bellutti Enders F, van Wijk F, Scholman R, Hofer M, Prakken BJ, van Royen-Kerkhof A, de Jager W.

Arthritis Rheumatol. 2014 Aug;66(8):2281-9. doi: 10.1002/art.38676.

22.

Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and modulation of the Teff cell compartment.

Delemarre EM, Roord ST, van den Broek T, Zonneveld-Huijssoon E, de Jager W, Rozemuller H, Martens AC, Broere F, Wulffraat NM, Glant TT, Prakken BJ, van Wijk F.

Arthritis Rheumatol. 2014 Feb;66(2):350-6. doi: 10.1002/art.38261.

23.

Allergen-specific Th2 responses in young children precede sensitization later in life.

Reubsaet LL, Meerding J, Scholman R, Arets B, Prakken BJ, van Wijk F, Knol EF.

Allergy. 2014 Mar;69(3):406-10. doi: 10.1111/all.12366. Epub 2014 Jan 28.

PMID:
24467266
24.

T cell recognition of naturally presented epitopes of self-heat shock protein 70.

de Jong H, Koffeman EC, Meerding JM, Scholman RC, Wieten L, de Jager W, Klein M, Otten H, van Wijk F, van der Zee R, Bijlsma JW, Broere F, van Eden W, Prakken BJ.

Cell Stress Chaperones. 2014 Jul;19(4):569-78. doi: 10.1007/s12192-013-0484-1. Epub 2014 Jan 15.

25.

Mesenchymal stem cell therapy in proteoglycan induced arthritis.

Swart JF, de Roock S, Hofhuis FM, Rozemuller H, van den Broek T, Moerer P, Broere F, van Wijk F, Kuis W, Prakken BJ, Martens AC, Wulffraat NM.

Ann Rheum Dis. 2015 Apr;74(4):769-77. doi: 10.1136/annrheumdis-2013-204147. Epub 2014 Jan 6.

PMID:
24395558
26.

Plasma IL-25 is elevated in a subgroup of patients with clinical reactivity to peanut.

Aalberse JA, van Thuijl AO, Meijer Y, de Jager W, van der Palen-Merkus T, Sprikkelman AB, Hoekstra MO, Prakken BJ, van Wijk F.

Clin Transl Allergy. 2013 Dec 2;3(1):40. doi: 10.1186/2045-7022-3-40.

27.

TH17 differentiation capacity develops within the first 3 months of life.

Dijkstra KK, Hoeks SB, Prakken BJ, de Roock S.

J Allergy Clin Immunol. 2014 Mar;133(3):891-4.e5. doi: 10.1016/j.jaci.2013.09.022. Epub 2013 Nov 1. No abstract available.

PMID:
24188977
28.

Differential homeostatic dynamics of human regulatory T-cell subsets following neonatal thymectomy.

Schadenberg AW, van den Broek T, Siemelink MA, Algra SO, de Jong PR, Jansen NJ, Prakken BJ, van Wijk F.

J Allergy Clin Immunol. 2014 Jan;133(1):277-80.e1-6. doi: 10.1016/j.jaci.2013.08.030. Epub 2013 Oct 18. No abstract available.

PMID:
24139831
29.

Plasma chemokines in early wheezers predict the development of allergic asthma.

Reubsaet LL, Meerding J, de Jager W, de Kleer IM, Hoekstra MO, Prakken BJ, van Wijk F, Arets HG.

Am J Respir Crit Care Med. 2013 Oct 15;188(8):1039-40. doi: 10.1164/rccm.201212-2330LE. No abstract available.

PMID:
24127809
30.

Anti-tumor necrosis factor α targets protein kinase B/c-Akt-induced resistance of effector cells to suppression in juvenile idiopathic arthritis.

Wehrens EJ, Vastert SJ, Mijnheer G, Meerding J, Klein M, Wulffraat NM, Prakken BJ, van Wijk F.

Arthritis Rheum. 2013 Dec;65(12):3279-84. doi: 10.1002/art.38132.

31.

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

van Loosdregt J, Fleskens V, Fu J, Brenkman AB, Bekker CP, Pals CE, Meerding J, Berkers CR, Barbi J, Gröne A, Sijts AJ, Maurice MM, Kalkhoven E, Prakken BJ, Ovaa H, Pan F, Zaiss DM, Coffer PJ.

Immunity. 2013 Aug 22;39(2):259-71. doi: 10.1016/j.immuni.2013.05.018.

32.

Canonical Wnt signaling negatively modulates regulatory T cell function.

van Loosdregt J, Fleskens V, Tiemessen MM, Mokry M, van Boxtel R, Meerding J, Pals CE, Kurek D, Baert MR, Delemarre EM, Gröne A, Koerkamp MJ, Sijts AJ, Nieuwenhuis EE, Maurice MM, van Es JH, Ten Berge D, Holstege FC, Staal FJ, Zaiss DM, Prakken BJ, Coffer PJ.

Immunity. 2013 Aug 22;39(2):298-310. doi: 10.1016/j.immuni.2013.07.019. Epub 2013 Aug 15.

33.

Defective TH17 development in human neonatal T cells involves reduced RORC2 mRNA content.

de Roock S, Stoppelenburg AJ, Scholman R, Hoeks SBEA, Meerding J, Prakken BJ, Boes M.

J Allergy Clin Immunol. 2013 Sep;132(3):754-756.e3. doi: 10.1016/j.jaci.2013.04.014. Epub 2013 May 29. No abstract available.

PMID:
23726039
34.

Cytokine assays: an assessment of the preparation and treatment of blood and tissue samples.

Keustermans GC, Hoeks SB, Meerding JM, Prakken BJ, de Jager W.

Methods. 2013 May 15;61(1):10-7. doi: 10.1016/j.ymeth.2013.04.005. Epub 2013 Apr 19. Review.

PMID:
23603216
35.

Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: a possible mechanism for therapeutic modulation of T cells.

van Loosdregt J, Spreafico R, Rossetti M, Prakken BJ, Lotz M, Albani S.

J Allergy Clin Immunol. 2013 May;131(5):1443-6.e1. doi: 10.1016/j.jaci.2013.02.026. Epub 2013 Mar 28. No abstract available.

36.

An urge for change: transitional care for young adults with juvenile idiopathic arthritis.

Ammerlaan JW, Scholtus LW, Bijlsma HJ, Prakken BJ, Kruize AA.

Patient Educ Couns. 2013 Jul;92(1):127-9. doi: 10.1016/j.pec.2013.02.006. Epub 2013 Mar 13. No abstract available.

PMID:
23490174
37.

Selection of perforin expressing CD4+ adenovirus-specific T-cells with artificial antigen presenting cells.

Haveman LM, Bierings M, Klein MR, Beekman JM, de Jager W, Kuis W, Albani S, Prakken BJ.

Clin Immunol. 2013 Mar;146(3):228-39. doi: 10.1016/j.clim.2013.01.002. Epub 2013 Jan 16.

PMID:
23416239
38.

Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery.

Algra SO, Groeneveld KM, Schadenberg AW, Haas F, Evens FC, Meerding J, Koenderman L, Jansen NJ, Prakken BJ.

J Neuroinflammation. 2013 Feb 7;10:24. doi: 10.1186/1742-2094-10-24.

39.

T cells out of control--impaired immune regulation in the inflamed joint.

Wehrens EJ, Prakken BJ, van Wijk F.

Nat Rev Rheumatol. 2013 Jan;9(1):34-42. doi: 10.1038/nrrheum.2012.149. Review.

PMID:
23390638
40.

The effect of autoimmune arthritis treatment strategies on regulatory T-cell dynamics.

Mijnheer G, Prakken BJ, van Wijk F.

Curr Opin Rheumatol. 2013 Mar;25(2):260-7. doi: 10.1097/BOR.0b013e32835d0ee4. Review.

PMID:
23274520
41.

Heat shock protein bystander antigens for peptide immunotherapy in autoimmune disease.

Zonneveld-Huijssoon E, Albani S, Prakken BJ, van Wijk F.

Clin Exp Immunol. 2013 Jan;171(1):20-9. doi: 10.1111/j.1365-2249.2012.04627.x. Review.

42.

Stem cell source-dependent reconstitution of FOXP3+ T cells after pediatric SCT and the association with allo-reactive disease.

Reubsaet LL, de Pagter AP, van Baarle D, Keukens L, Nanlohy N, Sanders EA, Prakken BJ, Boelens JJ, de Kleer IM.

Bone Marrow Transplant. 2013 Apr;48(4):502-7. doi: 10.1038/bmt.2012.174. Epub 2012 Sep 24.

PMID:
23000652
43.

Increased immune reactivity towards human hsp60 in patients with primary Sjögren's syndrome is associated with increased cytokine levels and glandular inflammation.

de Jong H, de Jager W, Wenting-van Wijk M, Prakken BJ, Kruize AA, Bijlsma JW, Lafeber FP, van Roon JA.

Clin Exp Rheumatol. 2012 Jul-Aug;30(4):594-5. Epub 2012 Aug 29. No abstract available.

PMID:
22931585
44.

Recognition of self-heat shock protein 60 by T cells from patients with atopic dermatitis.

Kapitein B, Aalberse JA, Klein MR, de Jager W, Hoekstra MO, Knol EF, Prakken BJ.

Cell Stress Chaperones. 2013 Jan;18(1):87-95. doi: 10.1007/s12192-012-0361-3. Epub 2012 Aug 7.

45.

HSP: Bystander Antigen in Atopic Diseases?

Aalberse JA, Prakken BJ, Kapitein B.

Front Immunol. 2012 May 31;3:139. doi: 10.3389/fimmu.2012.00139. eCollection 2012.

46.

TLR9 agonist CpG enhances protective nasal HSP60 peptide vaccine efficacy in experimental autoimmune arthritis.

Zonneveld-Huijssoon E, van Wijk F, Roord S, Delemarre E, Meerding J, de Jager W, Klein M, Raz E, Albani S, Kuis W, Boes M, Prakken BJ.

Ann Rheum Dis. 2012 Oct;71(10):1706-15. doi: 10.1136/annrheumdis-2011-201131. Epub 2012 May 5.

PMID:
22562976
47.

STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass.

de Jong PR, Schadenberg AW, van den Broek T, Beekman JM, van Wijk F, Coffer PJ, Prakken BJ, Jansen NJ.

PLoS One. 2012;7(4):e35070. doi: 10.1371/journal.pone.0035070. Epub 2012 Apr 10.

48.

Recognition of heat shock protein 60 epitopes in children with type 1 diabetes.

Verrijn Stuart AA, de Jager W, Klein MR, Teklenburg G, Nuboer R, Hoorweg JJ, de Vroede MA, de Kruijff I, Fick M, Schroor EJ, van der Vlist GJ, Meerding J, Kamphuis S, Prakken BJ.

Diabetes Metab Res Rev. 2012 Sep;28(6):527-34. doi: 10.1002/dmrr.2306.

PMID:
22492505
49.

Treatment-specific changes in circulating adipocytokines: a comparison between tumour necrosis factor blockade and glucocorticoid treatment for rheumatoid arthritis.

Klaasen R, Herenius MM, Wijbrandts CA, de Jager W, van Tuyl LH, Nurmohamed MT, Prakken BJ, Gerlag DM, Tak PP.

Ann Rheum Dis. 2012 Sep;71(9):1510-6. doi: 10.1136/annrheumdis-2011-200646. Epub 2012 Mar 22.

50.

Changing winds in refractory autoimmune disease in children: clearing the road for tolerance with cellular therapies.

Swart JF, Lindemans CA, van Royen A, Boelens JJ, Prakken BJ, Wulffraat N.

Curr Opin Rheumatol. 2012 May;24(3):267-73. doi: 10.1097/BOR.0b013e32835264f4. Review.

PMID:
22418744

Supplemental Content

Loading ...
Support Center