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Items: 1 to 50 of 208

1.

YAP/TAZ are Activated by Mechanical and Hormonal Stimuli in Myometrium and Exhibit Increased Baseline Activation in Uterine Fibroids.

Purdy MP, Ducharme M, Haak AJ, Ravix J, Tan Q, Sicard D, Prakash YS, Tschumperlin DJ, Stewart EA.

Reprod Sci. 2020 Feb 13. doi: 10.1007/s43032-019-00106-4. [Epub ahead of print]

PMID:
32056132
2.

The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality.

Li C, Zhu B, Son YM, Wang Z, Jiang L, Xiang M, Ye Z, Beckermann KE, Wu Y, Jenkins JW, Siska PJ, Vincent BG, Prakash YS, Peikert T, Edelson BT, Taneja R, Kaplan MH, Rathmell JC, Dong H, Hitosugi T, Sun J.

Immunity. 2020 Jan 14;52(1):201-202. doi: 10.1016/j.immuni.2019.12.008. No abstract available.

3.

Upregulation of airway smooth muscle calcium-sensing receptor by low-molecular-weight hyaluronan.

Lazrak A, Yu Z, Doran S, Jian MY, Creighton J, Laube M, Garantziotis S, Prakash YS, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2020 Mar 1;318(3):L459-L471. doi: 10.1152/ajplung.00429.2019. Epub 2020 Jan 8.

PMID:
31913654
4.

It's about time: clocks in the developing lung.

Bartman CM, Matveyenko A, Prakash YS.

J Clin Invest. 2020 Jan 2;130(1):39-50. doi: 10.1172/JCI130143. Review.

5.

Genetic variations in olfactory receptor gene OR2AG2 in a large multigenerational family with asthma.

Chakraborty S, Dakle P, Sinha A, Vishweswaraiah S, Nagori A, Salimath S, Prakash YS, Lodha R, Kabra SK, Ghosh B, Faruq M, Mahesh PA, Agrawal A.

Sci Rep. 2019 Dec 13;9(1):19029. doi: 10.1038/s41598-019-54718-6.

6.

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis.

Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ.

Sci Transl Med. 2019 Oct 30;11(516). pii: eaau6296. doi: 10.1126/scitranslmed.aau6296.

PMID:
31666402
7.

Differential estrogen-receptor activation regulates extracellular matrix deposition in human airway smooth muscle remodeling via NF-κB pathway.

Ambhore NS, Kalidhindi RSR, Pabelick CM, Hawse JR, Prakash YS, Sathish V.

FASEB J. 2019 Dec;33(12):13935-13950. doi: 10.1096/fj.201901340R. Epub 2019 Oct 22.

PMID:
31638834
8.

Estrogen receptors differentially regulate intracellular calcium handling in human nonasthmatic and asthmatic airway smooth muscle cells.

Bhallamudi S, Connell J, Pabelick CM, Prakash YS, Sathish V.

Am J Physiol Lung Cell Mol Physiol. 2020 Jan 1;318(1):L112-L124. doi: 10.1152/ajplung.00206.2019. Epub 2019 Oct 16.

PMID:
31617730
9.

The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality.

Li C, Zhu B, Son YM, Wang Z, Jiang L, Xiang M, Ye Z, Beckermann KE, Wu Y, Jenkins JW, Siska PJ, Vincent BG, Prakash YS, Peikert T, Edelson BT, Taneja R, Kaplan MH, Rathmell JC, Dong H, Hitosugi T, Sun J.

Immunity. 2019 Sep 17;51(3):491-507.e7. doi: 10.1016/j.immuni.2019.08.013. Erratum in: Immunity. 2020 Jan 14;52(1):201-202.

PMID:
31533057
10.

Moderate hyperoxia induces senescence in developing human lung fibroblasts.

You K, Parikh P, Khandalavala K, Wicher SA, Manlove L, Yang B, Roesler A, Roos BB, Teske JJ, Britt RD Jr, Pabelick CM, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L525-L536. doi: 10.1152/ajplung.00067.2019. Epub 2019 Aug 14.

PMID:
31411059
11.

Androgen Receptor-Mediated Regulation of Intracellular Calcium in Human Airway Smooth Muscle Cells.

Kalidhindi RSR, Katragadda R, Beauchamp KL, Pabelick CM, Prakash YS, Sathish V.

Cell Physiol Biochem. 2019;53(1):215-228. doi: 10.33594/000000131.

12.

PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state.

Caporarello N, Meridew JA, Jones DL, Tan Q, Haak AJ, Choi KM, Manlove LJ, Prakash YS, Tschumperlin DJ, Ligresti G.

Thorax. 2019 Aug;74(8):749-760. doi: 10.1136/thoraxjnl-2019-213064. Epub 2019 Jun 10.

13.

Airway Innervation and Plasticity in Asthma.

Kistemaker LEM, Prakash YS.

Physiology (Bethesda). 2019 Jul 1;34(4):283-298. doi: 10.1152/physiol.00050.2018. Review.

PMID:
31165683
14.

CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis.

Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ.

JCI Insight. 2019 May 16;5. pii: 127111. doi: 10.1172/jci.insight.127111.

15.

Caveolin-1 scaffolding domain peptide prevents hyperoxia-induced airway remodeling in a neonatal mouse model.

Vogel ER, Manlove LJ, Kuipers I, Thompson MA, Fang YH, Freeman MR, Britt RD Jr, Faksh A, Yang B, Prakash YS, Pabelick CM.

Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L99-L108. doi: 10.1152/ajplung.00111.2018. Epub 2019 May 1.

PMID:
31042080
16.

STIM1 expression is associated with osteosarcoma cell survival.

Zang J, Zuo D, Shogren KL, Gustafson CT, Zhou Z, Thompson MA, Guo R, Prakash YS, Lu L, Guo W, Maran A, Yaszemski MJ.

Chin J Cancer Res. 2019 Feb;31(1):203-211. doi: 10.21147/j.issn.1000-9604.2019.01.15.

17.

Senescence in the lung: is this getting old?

Morty RE, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2019 May 1;316(5):L822-L825. doi: 10.1152/ajplung.00081.2019. Epub 2019 Mar 20. No abstract available.

PMID:
30892079
18.

Cellular senescence in the lung across the age spectrum.

Parikh P, Wicher S, Khandalavala K, Pabelick CM, Britt RD Jr, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2019 May 1;316(5):L826-L842. doi: 10.1152/ajplung.00424.2018. Epub 2019 Feb 20. Review.

PMID:
30785345
19.

Caveolae, caveolin-1 and lung diseases of aging.

Wicher SA, Prakash YS, Pabelick CM.

Expert Rev Respir Med. 2019 Mar;13(3):291-300. doi: 10.1080/17476348.2019.1575733. Epub 2019 Feb 7.

PMID:
30686114
20.

Calcium sensing receptor in developing human airway smooth muscle.

Roesler AM, Wicher SA, Ravix J, Britt RD Jr, Manlove L, Teske JJ, Cummings K, Thompson MA, Farver C, MacFarlane P, Pabelick CM, Prakash YS.

J Cell Physiol. 2019 Aug;234(8):14187-14197. doi: 10.1002/jcp.28115. Epub 2019 Jan 9.

PMID:
30624783
21.

Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease.

Zhang J, Wang D, Wang L, Wang S, Roden AC, Zhao H, Li X, Prakash YS, Matteson EL, Tschumperlin DJ, Vassallo R.

Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L487-L497. doi: 10.1152/ajplung.00301.2018. Epub 2019 Jan 3.

22.

Hyperoxia-induced Cellular Senescence in Fetal Airway Smooth Muscle Cells.

Parikh P, Britt RD Jr, Manlove LJ, Wicher SA, Roesler A, Ravix J, Teske J, Thompson MA, Sieck GC, Kirkland JL, LeBrasseur N, Tschumperlin DJ, Pabelick CM, Prakash YS.

Am J Respir Cell Mol Biol. 2019 Jul;61(1):51-60. doi: 10.1165/rcmb.2018-0176OC.

PMID:
30508396
23.

Phrenic motoneuron structural plasticity across models of diaphragm muscle paralysis.

Mantilla CB, Zhan WZ, Gransee HM, Prakash YS, Sieck GC.

J Comp Neurol. 2018 Dec 15;526(18):2973-2983. doi: 10.1002/cne.24503. Epub 2018 Nov 8.

24.

Arhgef12 drives IL17A-induced airway contractility and airway hyperresponsiveness in mice.

Fong V, Hsu A, Wu E, Looney AP, Ganesan P, Ren X, Sheppard D, Wicher SA, Thompson MA, Britt RD Jr, Prakash YS, Bhattacharya M.

JCI Insight. 2018 Nov 2;3(21). pii: 123578. doi: 10.1172/jci.insight.123578.

25.

Smooth muscle brain-derived neurotrophic factor contributes to airway hyperreactivity in a mouse model of allergic asthma.

Britt RD Jr, Thompson MA, Wicher SA, Manlove LJ, Roesler A, Fang YH, Roos C, Smith L, Miller JD, Pabelick CM, Prakash YS.

FASEB J. 2019 Feb;33(2):3024-3034. doi: 10.1096/fj.201801002R. Epub 2018 Oct 23.

26.

Th1 cytokines TNF-α and IFN-γ promote corticosteroid resistance in developing human airway smooth muscle.

Britt RD Jr, Thompson MA, Sasse S, Pabelick CM, Gerber AN, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L71-L81. doi: 10.1152/ajplung.00547.2017. Epub 2018 Oct 18.

27.

Secretory Inositol Polyphosphate 4-Phosphatase Protects against Airway Inflammation and Remodeling.

Khanna K, Chaudhuri R, Aich J, Pattnaik B, Panda L, Prakash YS, Mabalirajan U, Ghosh B, Agrawal A.

Am J Respir Cell Mol Biol. 2019 Apr;60(4):399-412. doi: 10.1165/rcmb.2017-0353OC.

PMID:
30335467
28.

Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease.

Han MK, Arteaga-Solis E, Blenis J, Bourjeily G, Clegg DJ, DeMeo D, Duffy J, Gaston B, Heller NM, Hemnes A, Henske EP, Jain R, Lahm T, Lancaster LH, Lee J, Legato MJ, McKee S, Mehra R, Morris A, Prakash YS, Stampfli MR, Gopal-Srivastava R, Laposky AD, Punturieri A, Reineck L, Tigno X, Clayton J.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):850-858. doi: 10.1164/rccm.201801-0168WS. Review.

29.

Ca2+ Entry Through Reverse Mode Na+/Ca2+ Exchanger Contributes to Store Operated Channel-Mediated Neointima Formation After Arterial Injury.

Liu B, Zhang B, Huang S, Yang L, Roos CM, Thompson MA, Prakash YS, Zang J, Miller JD, Guo R.

Can J Cardiol. 2018 Jun;34(6):791-799. doi: 10.1016/j.cjca.2018.01.012. Epub 2018 Jan 31.

PMID:
29705161
30.

Estrogen receptor beta signaling inhibits PDGF induced human airway smooth muscle proliferation.

Ambhore NS, Katragadda R, Raju Kalidhindi RS, Thompson MA, Pabelick CM, Prakash YS, Sathish V.

Mol Cell Endocrinol. 2018 Nov 15;476:37-47. doi: 10.1016/j.mce.2018.04.007. Epub 2018 Apr 20.

31.

RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.

Oh RS, Haak AJ, Smith KMJ, Ligresti G, Choi KM, Xie T, Wang S, Walters PR, Thompson MA, Freeman MR, Manlove LJ, Chu VM, Feghali-Bostwick C, Roden AC, Schymeinsky J, Pabelick CM, Prakash YS, Vassallo R, Tschumperlin DJ.

J Cell Sci. 2018 May 15;131(10). pii: jcs209932. doi: 10.1242/jcs.209932.

32.

TRPC6 and TRPC4 Heteromultimerization Mediates Store Depletion-Activated NCX1 Reversal in Proliferative Vascular Smooth Muscle Cells.

Zhang B, Liu B, Roos CM, Thompson MA, Prakash YS, Miller JD, Guo RW.

Channels (Austin). 2018 Jan 1;12(1):119-125. doi: 10.1080/19336950.2018.1451696.

33.

Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses.

Cheon IS, Son YM, Jiang L, Goplen NP, Kaplan MH, Limper AH, Kita H, Paczesny S, Prakash YS, Tepper R, Ahlfeld SK, Sun J.

J Allergy Clin Immunol. 2018 Oct;142(4):1100-1112. doi: 10.1016/j.jaci.2017.11.025. Epub 2017 Dec 15.

34.

Hypoxia and Local Inflammation in Pulmonary Artery Structure and Function.

Thompson M, Britt RD Jr, Pabelick CM, Prakash YS.

Adv Exp Med Biol. 2017;967:325-334. doi: 10.1007/978-3-319-63245-2_20.

PMID:
29047096
35.

The -Omic Approach to Understanding Glucocorticoid Effects in Smooth Muscle: Diving for Pearls.

Britt R Jr, Prakash YS.

Am J Respir Cell Mol Biol. 2017 Aug;57(2):147-148. doi: 10.1165/rcmb.2017-0132ED. No abstract available.

36.

Brain-derived neurotrophic factor and airway fibrosis in asthma.

Freeman MR, Sathish V, Manlove L, Wang S, Britt RD Jr, Thompson MA, Pabelick CM, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L360-L370. doi: 10.1152/ajplung.00580.2016. Epub 2017 May 18.

37.

TNFα decreases mitochondrial movement in human airway smooth muscle.

Delmotte P, Zavaletta VA, Thompson MA, Prakash YS, Sieck GC.

Am J Physiol Lung Cell Mol Physiol. 2017 Jul 1;313(1):L166-L176. doi: 10.1152/ajplung.00538.2016. Epub 2017 May 4.

38.

Mitochondrial Dysfunction in Airway Disease.

Prakash YS, Pabelick CM, Sieck GC.

Chest. 2017 Sep;152(3):618-626. doi: 10.1016/j.chest.2017.03.020. Epub 2017 Mar 21. Review.

39.

Cellular senescence mediates fibrotic pulmonary disease.

Schafer MJ, White TA, Iijima K, Haak AJ, Ligresti G, Atkinson EJ, Oberg AL, Birch J, Salmonowicz H, Zhu Y, Mazula DL, Brooks RW, Fuhrmann-Stroissnigg H, Pirtskhalava T, Prakash YS, Tchkonia T, Robbins PD, Aubry MC, Passos JF, Kirkland JL, Tschumperlin DJ, Kita H, LeBrasseur NK.

Nat Commun. 2017 Feb 23;8:14532. doi: 10.1038/ncomms14532.

40.

An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling.

Prakash YS, Halayko AJ, Gosens R, Panettieri RA Jr, Camoretti-Mercado B, Penn RB; ATS Assembly on Respiratory Structure and Function.

Am J Respir Crit Care Med. 2017 Jan 15;195(2):e4-e19. doi: 10.1164/rccm.201611-2248ST.

PMID:
28084822
41.

Moderate hyperoxia induces extracellular matrix remodeling by human fetal airway smooth muscle cells.

Vogel ER, Britt RD Jr, Faksh A, Kuipers I, Pandya H, Prakash YS, Martin RJ, Pabelick CM.

Pediatr Res. 2017 Feb;81(2):376-383. doi: 10.1038/pr.2016.218. Epub 2016 Nov 3.

42.

An Official American Thoracic Society Workshop Report: Evaluation and Management of Asthma in the Elderly.

Skloot GS, Busse PJ, Braman SS, Kovacs EJ, Dixon AE, Vaz Fragoso CA, Scichilone N, Prakash YS, Pabelick CM, Mathur SK, Hanania NA, Moore WC, Gibson PG, Zieman S, Ragless BB; ATS ad hoc Committee on Asthma in the Elderly.

Ann Am Thorac Soc. 2016 Nov;13(11):2064-2077.

43.

Differential Expression of Estrogen Receptor Variants in Response to Inflammation Signals in Human Airway Smooth Muscle.

Aravamudan B, Goorhouse KJ, Unnikrishnan G, Thompson MA, Pabelick CM, Hawse JR, Prakash YS, Sathish V.

J Cell Physiol. 2017 Jul;232(7):1754-1760. doi: 10.1002/jcp.25674. Epub 2017 Feb 24.

44.

Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease.

Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2016 Dec 1;311(6):L1113-L1140. doi: 10.1152/ajplung.00370.2016. Epub 2016 Oct 14. Review.

45.

Functional Effects of Cigarette Smoke-Induced Changes in Airway Smooth Muscle Mitochondrial Morphology.

Aravamudan B, Thompson M, Sieck GC, Vassallo R, Pabelick CM, Prakash YS.

J Cell Physiol. 2017 May;232(5):1053-1068. doi: 10.1002/jcp.25508. Epub 2016 Sep 21.

46.

Author response to letter to editor: Hyperinsulinemia adversely affects lung structure and function.

Singh S, Bodas M, Bhatraju NK, Pattnaik B, Gheware A, Parameswaran PK, Thompson M, Freeman M, Mabalirajan U, Gosens R, Ghosh B, Pabelick C, Linneberg A, Prakash YS, Agrawal A.

Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1;311(1):L183-4. doi: 10.1152/ajplung.00227.2016. No abstract available.

47.

Mechanisms of BDNF regulation in asthmatic airway smooth muscle.

Aravamudan B, Thompson MA, Pabelick CM, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L270-9. doi: 10.1152/ajplung.00414.2015. Epub 2016 Jun 17.

48.

Restoration of Mitochondrial Cardiolipin Attenuates Cardiac Damage in Swine Renovascular Hypertension.

Eirin A, Ebrahimi B, Kwon SH, Fiala JA, Williams BJ, Woollard JR, He Q, Gupta RC, Sabbah HN, Prakash YS, Textor SC, Lerman A, Lerman LO.

J Am Heart Assoc. 2016 May 31;5(6). pii: e003118. doi: 10.1161/JAHA.115.003118.

49.

Vitamin D Reduces Inflammation-induced Contractility and Remodeling of Asthmatic Human Airway Smooth Muscle.

Britt RD Jr, Thompson MA, Freeman MR, Stewart AL, Pabelick CM, Prakash YS.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S97-8. doi: 10.1513/AnnalsATS.201508-540MG.

50.

Hyperinsulinemia adversely affects lung structure and function.

Singh S, Bodas M, Bhatraju NK, Pattnaik B, Gheware A, Parameswaran PK, Thompson M, Freeman M, Mabalirajan U, Gosens R, Ghosh B, Pabelick C, Linneberg A, Prakash YS, Agrawal A.

Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L837-45. doi: 10.1152/ajplung.00091.2015. Epub 2016 Feb 26.

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