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Items: 1 to 50 of 70

1.

How Does Aldosterone Work in the β-Intercalated Cell?

Leipziger J, Praetorius H.

J Am Soc Nephrol. 2020 Feb 13. pii: ASN.2020010077. doi: 10.1681/ASN.2020010077. [Epub ahead of print] No abstract available.

PMID:
32065116
2.

Renal autocrine and paracrine signaling -a story of self-protection.

Leipziger J, Praetorius HA.

Physiol Rev. 2020 Jan 30. doi: 10.1152/physrev.00014.2019. [Epub ahead of print]

PMID:
31999508
3.

P2X1 receptor blockers reduce the number of circulating thrombocytes and the overall survival of urosepsis with haemolysin-producing Escherichia coli.

Skals M, Greve AS, Fagerberg SK, Johnsen N, Christensen MG, Praetorius HA.

Purinergic Signal. 2019 Jun;15(2):265-276. doi: 10.1007/s11302-019-09658-1. Epub 2019 May 26.

4.

Lack of P2X7 Receptors Protects against Renal Fibrosis after Pyelonephritis with α-Hemolysin-Producing Escherichia coli.

Therkildsen JR, Christensen MG, Tingskov SJ, Wehmöller J, Nørregaard R, Praetorius HA.

Am J Pathol. 2019 Jun;189(6):1201-1211. doi: 10.1016/j.ajpath.2019.02.013. Epub 2019 Mar 27.

PMID:
30926332
5.

α-Haemolysin production, as a single factor, causes fulminant sepsis in a model of Escherichia coli-induced bacteraemia.

Johnsen N, Hamilton ADM, Greve AS, Christensen MG, Therkildsen JR, Wehmöller J, Skals M, Praetorius HA.

Cell Microbiol. 2019 Jun;21(6):e13017. doi: 10.1111/cmi.13017. Epub 2019 Mar 4.

PMID:
30761726
6.

Erythrocyte P2X1 receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis.

Fagerberg SK, Patel P, Andersen LW, Lui X, Donnino MW, Praetorius HA.

Crit Care. 2018 Aug 2;22(1):181. doi: 10.1186/s13054-018-2100-3.

7.

Comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis".

Volkov M, Dekkers J, Loos BG, Bizzarro S, Huizinga TWJ, Praetorius HA, Toes REM, van der Woude D.

Sci Transl Med. 2018 Mar 21;10(433). pii: eaan8349. doi: 10.1126/scitranslmed.aan8349.

PMID:
29563322
8.

Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response.

Sehgal P, Szalai P, Olesen C, Praetorius HA, Nissen P, Christensen SB, Engedal N, Møller JV.

J Biol Chem. 2017 Dec 1;292(48):19656-19673. doi: 10.1074/jbc.M117.796920. Epub 2017 Sep 29.

9.

Loop Diuretics Diminish Hemolysis Induced by α-Hemolysin from Escherichia coli.

Söderström CM, Fagerberg SK, Brogaard MB, Leipziger J, Skals M, Praetorius HA.

J Membr Biol. 2017 Jun;250(3):301-313. doi: 10.1007/s00232-017-9963-0. Epub 2017 May 9.

PMID:
28488084
10.

P2X1, P2X4, and P2X7 Receptor Knock Out Mice Expose Differential Outcome of Sepsis Induced by α-Haemolysin Producing Escherichia coli.

Greve AS, Skals M, Fagerberg SK, Tonnus W, Ellermann-Eriksen S, Evans RJ, Linkermann A, Praetorius HA.

Front Cell Infect Microbiol. 2017 Apr 6;7:113. doi: 10.3389/fcimb.2017.00113. eCollection 2017.

11.

Intact colonic KCa1.1 channel activity in KCNMB2 knockout mice.

Larsen CK, Praetorius HA, Leipziger J, Sorensen MV.

Physiol Rep. 2017 Mar;5(5). pii: e13179. doi: 10.14814/phy2.13179.

12.

P2X Receptors Inhibit NaCl Absorption in mTAL Independently of Nitric Oxide.

Svendsen SL, Isidor S, Praetorius HA, Leipziger J.

Front Physiol. 2017 Jan 24;8:18. doi: 10.3389/fphys.2017.00018. eCollection 2017.

13.

Inhibition of P2X Receptors Protects Human Monocytes against Damage by Leukotoxin from Aggregatibacter actinomycetemcomitans and α-Hemolysin from Escherichia coli.

Fagerberg SK, Jakobsen MR, Skals M, Praetorius HA.

Infect Immun. 2016 Oct 17;84(11):3114-3130. doi: 10.1128/IAI.00674-16. Print 2016 Nov.

14.

Hyperaldosteronism after decreased renal K+ excretion in KCNMB2 knockout mice.

Larsen CK, Jensen IS, Sorensen MV, de Bruijn PI, Bleich M, Praetorius HA, Leipziger J.

Am J Physiol Renal Physiol. 2016 May 15;310(10):F1035-46. doi: 10.1152/ajprenal.00010.2016. Epub 2016 Mar 9.

15.

Being dedicated.

Praetorius HA.

Am J Physiol Renal Physiol. 2015 Nov 15;309(10):F835. doi: 10.1152/ajprenal.00398.2015. Epub 2015 Sep 16. No abstract available.

16.

Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb.

de Bruijn PI, Larsen CK, Frische S, Himmerkus N, Praetorius HA, Bleich M, Leipziger J.

Am J Physiol Renal Physiol. 2015 Jul 15;309(2):F146-53.

17.

[Ca2+]i Oscillations and IL-6 Release Induced by α-Hemolysin from Escherichia coli Require P2 Receptor Activation in Renal Epithelia.

Christensen MG, Fagerberg SK, de Bruijn PI, Bjaelde RG, Jakobsen H, Leipziger J, Skals M, Praetorius HA.

J Biol Chem. 2015 Jun 5;290(23):14776-84. doi: 10.1074/jbc.M115.639526. Epub 2015 Apr 24.

18.

Sorting out the paracrine kidney.

Christensen MG, Praetorius HA.

Am J Physiol Renal Physiol. 2015 May 15;308(10):F1074-5. doi: 10.1152/ajprenal.00050.2015. Epub 2015 Feb 18. No abstract available.

19.

The primary cilium as sensor of fluid flow: new building blocks to the model. A review in the theme: cell signaling: proteins, pathways and mechanisms.

Praetorius HA.

Am J Physiol Cell Physiol. 2015 Feb 1;308(3):C198-208. doi: 10.1152/ajpcell.00336.2014. Epub 2014 Nov 26. Review.

20.

P2X receptors trigger intracellular alkalization in isolated perfused mouse medullary thick ascending limb.

de Bruijn PI, Bleich M, Praetorius HA, Leipziger J.

Acta Physiol (Oxf). 2015 Jan;213(1):277-84. doi: 10.1111/apha.12417. Epub 2014 Nov 24.

21.

Bacterial RTX toxins allow acute ATP release from human erythrocytes directly through the toxin pore.

Skals M, Bjaelde RG, Reinholdt J, Poulsen K, Vad BS, Otzen DE, Leipziger J, Praetorius HA.

J Biol Chem. 2014 Jul 4;289(27):19098-109. doi: 10.1074/jbc.M114.571414. Epub 2014 May 23.

22.

Sialic acid residues are essential for cell lysis mediated by leukotoxin from Aggregatibacter actinomycetemcomitans.

Munksgaard PS, Skals M, Reinholdt J, Poulsen K, Jensen MR, Yang C, Leipziger J, Vorup-Jensen T, Praetorius HA.

Infect Immun. 2014 Jun;82(6):2219-28. doi: 10.1128/IAI.01647-14. Epub 2014 Mar 18.

23.

Effects of high hydrostatic pressure on genomic expression profiling of porcine parthenogenetic activated and cloned embryos.

Lin L, Luo Y, Sørensen P, Prætorius H, Vajta G, Callesen H, Pribenszky C, Bolund L, Kristensen TN.

Reprod Fertil Dev. 2014 Mar;26(3):469-84. doi: 10.1071/RD13037.

PMID:
24618454
24.

P2Y2 receptor knock-out mice display normal NaCl absorption in medullary thick ascending limb.

Marques RD, Praetorius HA, Leipziger J.

Front Physiol. 2013 Oct 9;4:280. doi: 10.3389/fphys.2013.00280. eCollection 2013.

25.

Renal epithelial cells can release ATP by vesicular fusion.

Bjaelde RG, Arnadottir SS, Overgaard MT, Leipziger J, Praetorius HA.

Front Physiol. 2013 Sep 19;4:238. doi: 10.3389/fphys.2013.00238. eCollection 2013.

26.

Mechanisms of cytolysin-induced cell damage -- a role for auto- and paracrine signalling.

Skals M, Praetorius HA.

Acta Physiol (Oxf). 2013 Oct;209(2):95-113. doi: 10.1111/apha.12156. Epub 2013 Aug 28. Review.

PMID:
23927595
27.

P2X receptor-dependent erythrocyte damage by α-hemolysin from Escherichia coli triggers phagocytosis by THP-1 cells.

Fagerberg SK, Skals M, Leipziger J, Praetorius HA.

Toxins (Basel). 2013 Mar 5;5(3):472-87. doi: 10.3390/toxins5030472.

28.

Assessment of the effect of 24-hour aldosterone administration on protein abundance in fluorescence-sorted mouse distal renal tubules by mass spectrometry.

Jensen TB, Pisitkun T, Hoffert JD, Jensen UB, Fenton RA, Praetorius HA, Knepper MA, Praetorius J.

Nephron Physiol. 2012;121(3-4):p9-15. doi: 10.1159/000346832. Epub 2013 Feb 14.

29.

P2X receptor stimulation amplifies complement-induced haemolysis.

Hejl JL, Skals M, Leipziger J, Praetorius HA.

Pflugers Arch. 2013 Apr;465(4):529-41. doi: 10.1007/s00424-012-1174-z. Epub 2012 Nov 14.

PMID:
23149487
30.

Primary cilium-dependent sensing of urinary flow and paracrine purinergic signaling.

Praetorius HA, Leipziger J.

Semin Cell Dev Biol. 2013 Jan;24(1):3-10. doi: 10.1016/j.semcdb.2012.10.003. Epub 2012 Oct 17. Review.

PMID:
23085624
31.

Leukotoxin from Aggregatibacter actinomycetemcomitans causes shrinkage and P2X receptor-dependent lysis of human erythrocytes.

Munksgaard PS, Vorup-Jensen T, Reinholdt J, Söderström CM, Poulsen K, Leipziger J, Praetorius HA, Skals M.

Cell Microbiol. 2012 Dec;14(12):1904-20. doi: 10.1111/cmi.12021. Epub 2012 Sep 25.

PMID:
22906303
32.

Basolateral P2X receptors mediate inhibition of NaCl transport in mouse medullary thick ascending limb (mTAL).

Marques RD, de Bruijn PI, Sorensen MV, Bleich M, Praetorius HA, Leipziger J.

Am J Physiol Renal Physiol. 2012 Feb 15;302(4):F487-94. doi: 10.1152/ajprenal.00570.2011. Epub 2011 Nov 23.

33.

Python erythrocytes are resistant to α-hemolysin from Escherichia coli.

Larsen CK, Skals M, Wang T, Cheema MU, Leipziger J, Praetorius HA.

J Membr Biol. 2011 Dec;244(3):131-40. doi: 10.1007/s00232-011-9406-2. Epub 2011 Nov 8.

PMID:
22064954
34.

17β-Estradiol induces nongenomic effects in renal intercalated cells through G protein-coupled estrogen receptor 1.

Hofmeister MV, Damkier HH, Christensen BM, Olde B, Fredrik Leeb-Lundberg LM, Fenton RA, Praetorius HA, Praetorius J.

Am J Physiol Renal Physiol. 2012 Feb 1;302(3):F358-68. doi: 10.1152/ajprenal.00343.2011. Epub 2011 Oct 12.

35.

Agonists that increase [Ca²⁺](i) halt the movement of acidic cytoplasmic vesicles in MDCK cells.

Bjaelde RG, Arnadottir SS, Leipziger J, Praetorius HA.

J Membr Biol. 2011 Nov;244(1):43-53. doi: 10.1007/s00232-011-9396-0. Epub 2011 Oct 12.

PMID:
21989951
36.

Haemolysis induced by α-toxin from Staphylococcus aureus requires P2X receptor activation.

Skals M, Leipziger J, Praetorius HA.

Pflugers Arch. 2011 Nov;462(5):669-79. doi: 10.1007/s00424-011-1010-x. Epub 2011 Aug 17.

PMID:
21847558
37.

The secretory KCa1.1 channel localises to crypts of distal mouse colon: functional and molecular evidence.

Sørensen MV, Strandsby AB, Larsen CK, Praetorius HA, Leipziger J.

Pflugers Arch. 2011 Nov;462(5):745-52. doi: 10.1007/s00424-011-1000-z. Epub 2011 Aug 6.

PMID:
21822598
38.

Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus.

Olesen ET, Rützler MR, Moeller HB, Praetorius HA, Fenton RA.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12949-54. doi: 10.1073/pnas.1104691108. Epub 2011 Jul 18.

39.

Impaired aldosterone responsiveness in corticosteroid binding globulin deficient mice.

Sorensen MV, Praetorius HA, Nykjaer A, Willnow T, Leipziger J.

Acta Physiol (Oxf). 2011 Jan;201(1):169-77. doi: 10.1111/j.1748-1716.2010.02208.x. Epub 2010 Nov 12.

PMID:
20969731
40.

Adrenaline-induced colonic K+ secretion is mediated by KCa1.1 (BK) channels.

Sørensen MV, Sausbier M, Ruth P, Seidler U, Riederer B, Praetorius HA, Leipziger J.

J Physiol. 2010 May 15;588(Pt 10):1763-77. doi: 10.1113/jphysiol.2009.181933. Epub 2010 Mar 29.

41.

Escherichia coli alpha-hemolysin triggers shrinkage of erythrocytes via K(Ca)3.1 and TMEM16A channels with subsequent phosphatidylserine exposure.

Skals M, Jensen UB, Ousingsawat J, Kunzelmann K, Leipziger J, Praetorius HA.

J Biol Chem. 2010 May 14;285(20):15557-65. doi: 10.1074/jbc.M109.082578. Epub 2010 Mar 15.

42.

Intrarenal purinergic signaling in the control of renal tubular transport.

Praetorius HA, Leipziger J.

Annu Rev Physiol. 2010;72:377-93. doi: 10.1146/annurev-physiol-021909-135825. Review.

PMID:
20148681
43.

Colonic potassium handling.

Sorensen MV, Matos JE, Praetorius HA, Leipziger J.

Pflugers Arch. 2010 Apr;459(5):645-56. doi: 10.1007/s00424-009-0781-9. Epub 2010 Feb 10. Review.

PMID:
20143237
44.

AVP-stimulated nucleotide secretion in perfused mouse medullary thick ascending limb and cortical collecting duct.

Odgaard E, Praetorius HA, Leipziger J.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F341-9. doi: 10.1152/ajprenal.00190.2009. Epub 2009 Jun 10.

45.

Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells.

Praetorius HA, Leipziger J.

Acta Physiol (Oxf). 2009 Nov;197(3):241-51. doi: 10.1111/j.1748-1716.2009.02002.x. Epub 2009 May 11.

PMID:
19432587
46.

ATP release from non-excitable cells.

Praetorius HA, Leipziger J.

Purinergic Signal. 2009 Dec;5(4):433-46. doi: 10.1007/s11302-009-9146-2. Epub 2009 Mar 20.

47.

Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis.

Skals M, Jorgensen NR, Leipziger J, Praetorius HA.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4030-5. doi: 10.1073/pnas.0807044106. Epub 2009 Feb 18.

48.

Measuring cilium-induced Ca2+ increases in cultured renal epithelia.

Praetorius HA.

Methods Cell Biol. 2009;91:299-313. doi: 10.1016/S0091-679X(08)91016-5. Epub 2009 Dec 1.

PMID:
20409793
49.
50.

Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion.

Sørensen MV, Matos JE, Sausbier M, Sausbier U, Ruth P, Praetorius HA, Leipziger J.

J Physiol. 2008 Sep 1;586(17):4251-64. doi: 10.1113/jphysiol.2008.156968. Epub 2008 Jul 10.

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