Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.

Daumke O, Praefcke GJK.

Biopolymers. 2018 Feb;109(2). doi: 10.1002/bip.23079. Epub 2017 Nov 17. No abstract available.


Regulation of innate immune functions by guanylate-binding proteins.

Praefcke GJK.

Int J Med Microbiol. 2017 Nov 2. pii: S1438-4221(17)30425-3. doi: 10.1016/j.ijmm.2017.10.013. [Epub ahead of print] Review.


Disruption of the plant-specific CFS1 gene impairs autophagosome turnover and triggers EDS1-dependent cell death.

Sutipatanasomboon A, Herberth S, Alwood EG, Häweker H, Müller B, Shahriari M, Zienert AY, Marin B, Robatzek S, Praefcke GJK, Ayscough KR, Hülskamp M, Schellmann S.

Sci Rep. 2017 Aug 17;7(1):8677. doi: 10.1038/s41598-017-08577-8.


Nucleotide-dependent farnesyl switch orchestrates polymerization and membrane binding of human guanylate-binding protein 1.

Shydlovskyi S, Zienert AY, Ince S, Dovengerds C, Hohendahl A, Dargazanli JM, Blum A, Günther SD, Kladt N, Stürzl M, Schauss AC, Kutsch M, Roux A, Praefcke GJK, Herrmann C.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5559-E5568. doi: 10.1073/pnas.1620959114. Epub 2017 Jun 23.


Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.

Daumke O, Praefcke GJ.

Biopolymers. 2016 Aug;105(8):580-93. doi: 10.1002/bip.22855. Review. Erratum in: Biopolymers. 2018 Feb;109 (2):.


Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation.

Kuhlmann N, Wroblowski S, Knyphausen P, de Boor S, Brenig J, Zienert AY, Meyer-Teschendorf K, Praefcke GJ, Nolte H, Krüger M, Schacherl M, Baumann U, James LC, Chin JW, Lammers M.

J Biol Chem. 2016 Mar 11;291(11):5484-99. doi: 10.1074/jbc.M115.707091. Epub 2015 Dec 30.


Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor.

Ostler N, Britzen-Laurent N, Liebl A, Naschberger E, Lochnit G, Ostler M, Forster F, Kunzelmann P, Ince S, Supper V, Praefcke GJ, Schubert DW, Stockinger H, Herrmann C, Stürzl M.

Mol Cell Biol. 2014 Jan;34(2):196-209. doi: 10.1128/MCB.00664-13. Epub 2013 Nov 4.


Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO.

Keusekotten K, Bade VN, Meyer-Teschendorf K, Sriramachandran AM, Fischer-Schrader K, Krause A, Horst C, Schwarz G, Hofmann K, Dohmen RJ, Praefcke GJ.

Biochem J. 2014 Jan 1;457(1):207-14. doi: 10.1042/BJ20130753.


The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.

Kravets E, Degrandi D, Weidtkamp-Peters S, Ries B, Konermann C, Felekyan S, Dargazanli JM, Praefcke GJ, Seidel CA, Schmitt L, Smits SH, Pfeffer K.

J Biol Chem. 2012 Aug 10;287(33):27452-66. doi: 10.1074/jbc.M112.379636. Epub 2012 Jun 22.


Covalent protein modification with ISG15 via a conserved cysteine in the hinge region.

Bade VN, Nickels J, Keusekotten K, Praefcke GJ.

PLoS One. 2012;7(6):e38294. doi: 10.1371/journal.pone.0038294. Epub 2012 Jun 5.


Reconstitution of SUMO-dependent ubiquitylation in vitro.

Keusekotten K, Praefcke GJ.

Methods Mol Biol. 2012;832:111-23. doi: 10.1007/978-1-61779-474-2_6.


Analysis of cellular SUMO and SUMO-ubiquitin hybrid conjugates.

Schnellhardt M, Uzunova K, Bade VN, Krause A, Weisshaar SR, Praefcke GJ, Dohmen RJ.

Methods Mol Biol. 2012;832:81-92. doi: 10.1007/978-1-61779-474-2_4.


SUMO playing tag with ubiquitin.

Praefcke GJ, Hofmann K, Dohmen RJ.

Trends Biochem Sci. 2012 Jan;37(1):23-31. doi: 10.1016/j.tibs.2011.09.002. Epub 2011 Oct 20. Review.


Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion.

Anton F, Fres JM, Schauss A, Pinson B, Praefcke GJ, Langer T, Escobar-Henriques M.

J Cell Sci. 2011 Apr 1;124(Pt 7):1126-35. doi: 10.1242/jcs.073080. Epub 2011 Mar 8.


Structural insights into membrane fusion at the endoplasmic reticulum.

Daumke O, Praefcke GJ.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2175-6. doi: 10.1073/pnas.1019194108. Epub 2011 Jan 28. No abstract available.


Sumoylation as a signal for polyubiquitylation and proteasomal degradation.

Miteva M, Keusekotten K, Hofmann K, Praefcke GJ, Dohmen RJ.

Subcell Biochem. 2010;54:195-214. doi: 10.1007/978-1-4419-6676-6_16.


Purification of the CaaX-modified, dynamin-related large GTPase hGBP1 by coexpression with farnesyltransferase.

Fres JM, Müller S, Praefcke GJ.

J Lipid Res. 2010 Aug;51(8):2454-9. doi: 10.1194/jlr.D005397. Epub 2010 Mar 28.


Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML.

Weisshaar SR, Keusekotten K, Krause A, Horst C, Springer HM, Göttsche K, Dohmen RJ, Praefcke GJ.

FEBS Lett. 2008 Sep 22;582(21-22):3174-8. doi: 10.1016/j.febslet.2008.08.008. Epub 2008 Aug 15.


Solitary and repetitive binding motifs for the AP2 complex alpha-appendage in amphiphysin and other accessory proteins.

Olesen LE, Ford MG, Schmid EM, Vallis Y, Babu MM, Li PH, Mills IG, McMahon HT, Praefcke GJ.

J Biol Chem. 2008 Feb 22;283(8):5099-109. Epub 2007 Nov 6.


Ubiquitin-dependent proteolytic control of SUMO conjugates.

Uzunova K, Göttsche K, Miteva M, Weisshaar SR, Glanemann C, Schnellhardt M, Niessen M, Scheel H, Hofmann K, Johnson ES, Praefcke GJ, Dohmen RJ.

J Biol Chem. 2007 Nov 23;282(47):34167-75. Epub 2007 Aug 29.


Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly.

Schmid EM, Ford MG, Burtey A, Praefcke GJ, Peak-Chew SY, Mills IG, Benmerah A, McMahon HT.

PLoS Biol. 2006 Sep;4(9):e262.


Transient kinetic investigation of GTP hydrolysis catalyzed by interferon-gamma-induced hGBP1 (human guanylate binding protein 1).

Kunzelmann S, Praefcke GJ, Herrmann C.

J Biol Chem. 2006 Sep 29;281(39):28627-35. Epub 2006 Jul 27.


How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP.

Ghosh A, Praefcke GJ, Renault L, Wittinghofer A, Herrmann C.

Nature. 2006 Mar 2;440(7080):101-4.


Nucleotide binding and self-stimulated GTPase activity of human guanylate-binding protein 1 (hGBP1).

Kunzelmann S, Praefcke GJ, Herrmann C.

Methods Enzymol. 2005;404:512-27.


Clathrin-dependent and clathrin-independent retrieval of synaptic vesicles in retinal bipolar cells.

Jockusch WJ, Praefcke GJ, McMahon HT, Lagnado L.

Neuron. 2005 Jun 16;46(6):869-78.


Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis.

Praefcke GJ, Kloep S, Benscheid U, Lilie H, Prakash B, Herrmann C.

J Mol Biol. 2004 Nov 12;344(1):257-69.


Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis.

Praefcke GJ, Ford MG, Schmid EM, Olesen LE, Gallop JL, Peak-Chew SY, Vallis Y, Babu MM, Mills IG, McMahon HT.

EMBO J. 2004 Nov 10;23(22):4371-83. Epub 2004 Oct 21.


The dynamin superfamily: universal membrane tubulation and fission molecules?

Praefcke GJ, McMahon HT.

Nat Rev Mol Cell Biol. 2004 Feb;5(2):133-47. Review.


Structural basis for binding of accessory proteins by the appendage domain of GGAs.

Collins BM, Praefcke GJ, Robinson MS, Owen DJ.

Nat Struct Biol. 2003 Aug;10(8):607-13.


IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization.

Uthaiah RC, Praefcke GJ, Howard JC, Herrmann C.

J Biol Chem. 2003 Aug 1;278(31):29336-43. Epub 2003 May 5.


EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking.

Mills IG, Praefcke GJ, Vallis Y, Peter BJ, Olesen LE, Gallop JL, Butler PJ, Evans PR, McMahon HT.

J Cell Biol. 2003 Jan 20;160(2):213-22. Epub 2003 Jan 21.


Curvature of clathrin-coated pits driven by epsin.

Ford MG, Mills IG, Peter BJ, Vallis Y, Praefcke GJ, Evans PR, McMahon HT.

Nature. 2002 Sep 26;419(6905):361-6.


Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism.

Prakash B, Renault L, Praefcke GJ, Herrmann C, Wittinghofer A.

EMBO J. 2000 Sep 1;19(17):4555-64.


Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.

Prakash B, Praefcke GJ, Renault L, Wittinghofer A, Herrmann C.

Nature. 2000 Feb 3;403(6769):567-71.


Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif.

Praefcke GJ, Geyer M, Schwemmle M, Robert Kalbitzer H, Herrmann C.

J Mol Biol. 1999 Sep 17;292(2):321-32.


Supplemental Content

Loading ...
Support Center