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Oxaliplatin-Biomimetic Magnetic Nanoparticle Assemblies for Colon Cancer-Targeted Chemotherapy: An In Vitro Study.

Jabalera Y, Garcia-Pinel B, Ortiz R, Iglesias G, Cabeza L, Prados J, Jimenez-Lopez C, Melguizo C.

Pharmaceutics. 2019 Aug 6;11(8). pii: E395. doi: 10.3390/pharmaceutics11080395.


Genetic resistance to DEHP-induced transgenerational endocrine disruption.

Stenz L, Rahban R, Prados J, Nef S, Paoloni-Giacobino A.

PLoS One. 2019 Jun 10;14(6):e0208371. doi: 10.1371/journal.pone.0208371. eCollection 2019.


Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

Telley L, Agirman G, Prados J, Amberg N, Fièvre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D.

Science. 2019 May 10;364(6440). pii: eaav2522. doi: 10.1126/science.aav2522.


Electrospun Nanofibers: Recent Applications in Drug Delivery and Cancer Therapy.

Contreras-Cáceres R, Cabeza L, Perazzoli G, Díaz A, López-Romero JM, Melguizo C, Prados J.

Nanomaterials (Basel). 2019 Apr 24;9(4). pii: E656. doi: 10.3390/nano9040656. Review.


Lipid-Based Nanoparticles: Application and Recent Advances in Cancer Treatment.

García-Pinel B, Porras-Alcalá C, Ortega-Rodríguez A, Sarabia F, Prados J, Melguizo C, López-Romero JM.

Nanomaterials (Basel). 2019 Apr 19;9(4). pii: E638. doi: 10.3390/nano9040638. Review.


Leukemia multiclass assessment and classification from Microarray and RNA-seq technologies integration at gene expression level.

Castillo D, Galvez JM, Herrera LJ, Rojas F, Valenzuela O, Caba O, Prados J, Rojas I.

PLoS One. 2019 Feb 12;14(2):e0212127. doi: 10.1371/journal.pone.0212127. eCollection 2019.


An updated review of adipose derived-mesenchymal stem cells and their applications in musculoskeletal disorders.

Rivera-Izquierdo M, Cabeza L, Láinez-Ramos-Bossini A, Quesada R, Perazzoli G, Alvarez P, Prados J, Melguizo C.

Expert Opin Biol Ther. 2019 Mar;19(3):233-248. doi: 10.1080/14712598.2019.1563069. Epub 2019 Jan 25. Review.


A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer.

Jiménez-López J, El-Hammadi MM, Ortiz R, Cayero-Otero MD, Cabeza L, Perazzoli G, Martin-Banderas L, Baeyens JM, Prados J, Melguizo C.

Pharmacol Res. 2019 Mar;141:451-465. doi: 10.1016/j.phrs.2019.01.013. Epub 2019 Jan 8.


Factors Explaining Language Performance After Training in Elders With and Without Subjective Cognitive Decline.

López-Higes R, Prados JM, Rubio-Valdehita S, Rodríguez-Rojo I, de Frutos-Lucas J, Montenegro M, Montejo P, Prada D, Losada MLD.

Front Aging Neurosci. 2018 Sep 3;10:264. doi: 10.3389/fnagi.2018.00264. eCollection 2018.


Downregulated microRNAs in the colorectal cancer: diagnostic and therapeutic perspectives.

Hernández R, Sánchez-Jiménez E, Melguizo C, Prados J, Rama AR.

BMB Rep. 2018 Nov;51(11):563-571. Review.


Formulation and in vitro evaluation of magnetoliposomes as a potential nanotool in colorectal cancer therapy.

Lorente C, Cabeza L, Clares B, Ortiz R, Halbaut L, Delgado ÁV, Perazzoli G, Prados J, Arias JL, Melguizo C.

Colloids Surf B Biointerfaces. 2018 Nov 1;171:553-565. doi: 10.1016/j.colsurfb.2018.07.070. Epub 2018 Jul 31.


Study of aggregation in therapeutic monoclonal antibodies subjected to stress and long-term stability tests by analyzing size exclusion liquid chromatographic profiles.

Hernández-Jiménez J, Martínez-Ortega A, Salmerón-García A, Cabeza J, Prados JC, Ortíz R, Navas N.

Int J Biol Macromol. 2018 Oct 15;118(Pt A):511-524. doi: 10.1016/j.ijbiomac.2018.06.105. Epub 2018 Jun 23.


Latest in Vitro and in Vivo Assay, Clinical Trials and Patents in Cancer Treatment using Curcumin: A Literature Review.

Doello K, Ortiz R, Alvarez PJ, Melguizo C, Cabeza L, Prados J.

Nutr Cancer. 2018 May-Jun;70(4):569-578. doi: 10.1080/01635581.2018.1464347. Epub 2018 Apr 30. Review.


Proteomic biomarkers in body fluids associated with pancreatic cancer.

Jimenez-Luna C, Torres C, Ortiz R, Dieguez C, Martinez-Galan J, Melguizo C, Prados JC, Caba O.

Oncotarget. 2018 Mar 27;9(23):16573-16587. doi: 10.18632/oncotarget.24654. eCollection 2018 Mar 27. Review.


Integrative multi-platform meta-analysis of gene expression profiles in pancreatic ductal adenocarcinoma patients for identifying novel diagnostic biomarkers.

Irigoyen A, Jimenez-Luna C, Benavides M, Caba O, Gallego J, Ortuño FM, Guillen-Ponce C, Rojas I, Aranda E, Torres C, Prados J.

PLoS One. 2018 Apr 4;13(4):e0194844. doi: 10.1371/journal.pone.0194844. eCollection 2018.


Neurogliaform cortical interneurons derive from cells in the preoptic area.

Niquille M, Limoni G, Markopoulos F, Cadilhac C, Prados J, Holtmaat A, Dayer A.

Elife. 2018 Mar 20;7. pii: e32017. doi: 10.7554/eLife.32017.


Efficacy of Cognitive Training in Older Adults with and without Subjective Cognitive Decline Is Associated with Inhibition Efficiency and Working Memory Span, Not with Cognitive Reserve.

López-Higes R, Martín-Aragoneses MT, Rubio-Valdehita S, Delgado-Losada ML, Montejo P, Montenegro M, Prados JM, de Frutos-Lucas J, López-Sanz D.

Front Aging Neurosci. 2018 Feb 2;10:23. doi: 10.3389/fnagi.2018.00023. eCollection 2018.


Nano-engineering of biomedical prednisolone liposomes: evaluation of the cytotoxic effect on human colon carcinoma cell lines.

Lorente C, Arias JL, Cabeza L, Ortiz R, Prados JC, Melguizo C, Delgado ÁV, Clares-Naveros B.

J Pharm Pharmacol. 2018 Apr;70(4):488-497. doi: 10.1111/jphp.12882. Epub 2018 Jan 30.


Nanoemulsion Strategy for Ursolic and Oleanic Acids Isolates from Plumeria Obtusa Improves Antioxidant and Cytotoxic Activity in Melanoma Cells.

Alvarado HL, Calpena AC, Garduño-Ramírez ML, Ortiz R, Melguizo C, Prados JC, Clares B.

Anticancer Agents Med Chem. 2018;18(6):847-853. doi: 10.2174/1871520618666180111151846.


Dissociation of place preference and tolerance responses to sucrose using a dopamine antagonist in the planarian.

Mohammed Jawad RA, Hutchinson CV, Prados J.

Psychopharmacology (Berl). 2018 Mar;235(3):829-836. doi: 10.1007/s00213-017-4801-8. Epub 2017 Dec 2.


Tripalmitin nanoparticle formulations significantly enhance paclitaxel antitumor activity against breast and lung cancer cells in vitro.

Leiva MC, Ortiz R, Contreras-Cáceres R, Perazzoli G, Mayevych I, López-Romero JM, Sarabia F, Baeyens JM, Melguizo C, Prados J.

Sci Rep. 2017 Oct 18;7(1):13506. doi: 10.1038/s41598-017-13816-z.


Inter-hemispherical asymmetry in default-mode functional connectivity and BAIAP2 gene are associated with anger expression in ADHD adults.

Hasler R, Preti MG, Meskaldji DE, Prados J, Adouan W, Rodriguez C, Toma S, Hiller N, Ismaili T, Hofmeister J, Sinanaj I, Baud P, Haller S, Giannakopoulos P, Schwartz S, Perroud N, Van De Ville D.

Psychiatry Res Neuroimaging. 2017 Nov 30;269:54-61. doi: 10.1016/j.pscychresns.2017.09.004. Epub 2017 Sep 12.


Development of biomedical 5-fluorouracil nanoplatforms for colon cancer chemotherapy: Influence of process and formulation parameters.

Pretel E, Arias JL, Cabeza L, Melguizo C, Prados J, Mallandrich M, Suñer J, Clares B.

Int J Pharm. 2017 Sep 15;530(1-2):155-164. doi: 10.1016/j.ijpharm.2017.07.055. Epub 2017 Jul 22.


APOE ε4 Modulation of Training Outcomes in Several Cognitive Domains in a Sample of Cognitively Intact Older Adults.

López-Higes R, Rodríguez-Rojo IC, Prados JM, Montejo P, Del-Río D, Delgado-Losada ML, Montenegro M, López-Sanz D, Barabash A.

J Alzheimers Dis. 2017;58(4):1201-1215. doi: 10.3233/JAD-161014.


Development and Characterization of Magnetite/Poly(butylcyanoacrylate) Nanoparticles for Magnetic Targeted Delivery of Cancer Drugs.

López-Viota M, El-Hammadi MM, Cabeza L, Prados J, Melguizo C, Ruiz Martinez MA, Arias JL, Delgado ÁV.

AAPS PharmSciTech. 2017 Nov;18(8):3042-3052. doi: 10.1208/s12249-017-0792-3. Epub 2017 May 15.


Transient Cell-intrinsic Activity Regulates the Migration and Laminar Positioning of Cortical Projection Neurons.

Hurni N, Kolodziejczak M, Tomasello U, Badia J, Jacobshagen M, Prados J, Dayer A.

Cereb Cortex. 2017 May 1;27(5):3052-3063. doi: 10.1093/cercor/bhx059.


Improved antitumor activity and reduced toxicity of doxorubicin encapsulated in poly(ε-caprolactone) nanoparticles in lung and breast cancer treatment: An in vitro and in vivo study.

Cabeza L, Ortiz R, Prados J, Delgado ÁV, Martín-Villena MJ, Clares B, Perazzoli G, Entrena JM, Melguizo C, Arias JL.

Eur J Pharm Sci. 2017 May 1;102:24-34. doi: 10.1016/j.ejps.2017.02.026. Epub 2017 Feb 17.


Transcriptomic and anatomic parcellation of 5-HT3AR expressing cortical interneuron subtypes revealed by single-cell RNA sequencing.

Frazer S, Prados J, Niquille M, Cadilhac C, Markopoulos F, Gomez L, Tomasello U, Telley L, Holtmaat A, Jabaudon D, Dayer A.

Nat Commun. 2017 Jan 30;8:14219. doi: 10.1038/ncomms14219.


Executive functions and linguistic performance in SCD older adults and healthy controls.

López-Higes R, Prados JM, Rubio S, Montejo P, Del Río D.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2017 Nov;24(6):717-734. doi: 10.1080/13825585.2016.1256370. Epub 2016 Nov 14.


Folic acid-decorated and PEGylated PLGA nanoparticles for improving the antitumour activity of 5-fluorouracil.

El-Hammadi MM, Delgado ÁV, Melguizo C, Prados JC, Arias JL.

Int J Pharm. 2017 Jan 10;516(1-2):61-70. doi: 10.1016/j.ijpharm.2016.11.012. Epub 2016 Nov 5.


Identification of gene expression profiling associated with erlotinib-related skin toxicity in pancreatic adenocarcinoma patients.

Caba O, Irigoyen A, Jimenez-Luna C, Benavides M, Ortuño FM, Gallego J, Rojas I, Guillen-Ponce C, Torres C, Aranda E, Prados J.

Toxicol Appl Pharmacol. 2016 Nov 15;311:113-116. doi: 10.1016/j.taap.2016.10.003. Epub 2016 Oct 6.


Untargeted LC-HRMS-Based Metabolomics for Searching New Biomarkers of Pancreatic Ductal Adenocarcinoma: A Pilot Study.

Ríos Peces S, Díaz Navarro C, Márquez López C, Caba O, Jiménez-Luna C, Melguizo C, Prados JC, Genilloud O, Vicente Pérez F, Pérez Del Palacio J.

SLAS Discov. 2017 Apr;22(4):348-359. doi: 10.1177/1087057116671490. Epub 2016 Sep 27.


Correction: Decay-Initiating Endoribonucleolytic Cleavage by RNase Y Is Kept under Tight Control via Sequence Preference and Sub-cellular Localisation.

Khemici V, Prados J, Linder P, Redder P.

PLoS Genet. 2016 Sep 14;12(9):e1006320. doi: 10.1371/journal.pgen.1006320. eCollection 2016 Sep.


Current Status of Immunotherapy Treatments for Pancreatic Cancer.

Jimenez-Luna C, Prados J, Ortiz R, Melguizo C, Torres C, Caba O.

J Clin Gastroenterol. 2016 Nov/Dec;50(10):836-848. Review.


Perceptual learning transfer in an appetitive Pavlovian task.

Artigas AA, Prados J.

Learn Behav. 2017 Jun;45(2):115-123. doi: 10.3758/s13420-016-0245-y.


Rifampin Resistance rpoB Alleles or Multicopy Thioredoxin/Thioredoxin Reductase Suppresses the Lethality of Disruption of the Global Stress Regulator spx in Staphylococcus aureus.

Villanueva M, Jousselin A, Baek KT, Prados J, Andrey DO, Renzoni A, Ingmer H, Frees D, Kelley WL.

J Bacteriol. 2016 Sep 9;198(19):2719-31. doi: 10.1128/JB.00261-16. Print 2016 Oct 1.


Magnetic solid lipid nanoparticles in hyperthermia against colon cancer.

Muñoz de Escalona M, Sáez-Fernández E, Prados JC, Melguizo C, Arias JL.

Int J Pharm. 2016 May 17;504(1-2):11-9. doi: 10.1016/j.ijpharm.2016.03.005. Epub 2016 Mar 8.


Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex.

Telley L, Govindan S, Prados J, Stevant I, Nef S, Dermitzakis E, Dayer A, Jabaudon D.

Science. 2016 Mar 25;351(6280):1443-6. doi: 10.1126/science.aad8361. Epub 2016 Mar 3.


Enhanced antitumoral activity of doxorubicin against lung cancer cells using biodegradable poly(butylcyanoacrylate) nanoparticles.

Melguizo C, Cabeza L, Prados J, Ortiz R, Caba O, Rama AR, Delgado ÁV, Arias JL.

Drug Des Devel Ther. 2015 Dec 14;9:6433-44. doi: 10.2147/DDDT.S92273. eCollection 2015.


Tissue Specific Promoters in Colorectal Cancer.

Rama AR, Aguilera A, Melguizo C, Caba O, Prados J.

Dis Markers. 2015;2015:390161. doi: 10.1155/2015/390161. Epub 2015 Nov 15. Review.


Last Advances in Nanocarriers-Based Drug Delivery Systems for Colorectal Cancer.

Rama AR, Jimenez-Lopez J, Cabeza L, Jimenez-Luna C, Leiva MC, Perazzoli G, Hernandez R, Zafra I, Ortiz R, Melguizo C, Prados J.

Curr Drug Deliv. 2016;13(6):830-8. Review.


Decay-Initiating Endoribonucleolytic Cleavage by RNase Y Is Kept under Tight Control via Sequence Preference and Sub-cellular Localisation.

Khemici V, Prados J, Linder P, Redder P.

PLoS Genet. 2015 Oct 16;11(10):e1005577. doi: 10.1371/journal.pgen.1005577. eCollection 2015 Oct. Erratum in: PLoS Genet. 2016 Sep;12(9):e1006320.


Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression.

Perazzoli G, Prados J, Ortiz R, Caba O, Cabeza L, Berdasco M, Gónzalez B, Melguizo C.

PLoS One. 2015 Oct 8;10(10):e0140131. doi: 10.1371/journal.pone.0140131. eCollection 2015.


Prognosis Relevance of Serum Cytokines in Pancreatic Cancer.

Torres C, Linares A, Alejandre MJ, Palomino-Morales RJ, Caba O, Prados J, Aránega A, Delgado JR, Irigoyen A, Martínez-Galán J, Ortuño FM, Rojas I, Perales S.

Biomed Res Int. 2015;2015:518284. doi: 10.1155/2015/518284. Epub 2015 Aug 4.


Prenatal Exposure to DEHP Affects Spermatogenesis and Sperm DNA Methylation in a Strain-Dependent Manner.

Prados J, Stenz L, Somm E, Stouder C, Dayer A, Paoloni-Giacobino A.

PLoS One. 2015 Aug 5;10(7):e0132136. doi: 10.1371/journal.pone.0132136. eCollection 2015.


Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells.

Farace C, Oliver JA, Melguizo C, Alvarez P, Bandiera P, Rama AR, Malaguarnera G, Ortiz R, Madeddu R, Prados J.

PLoS One. 2015 Jul 31;10(7):e0134111. doi: 10.1371/journal.pone.0134111. eCollection 2015.


Specific Colon Cancer Cell Cytotoxicity Induced by Bacteriophage E Gene Expression under Transcriptional Control of Carcinoembryonic Antigen Promoter.

Rama AR, Hernandez R, Perazzoli G, Burgos M, Melguizo C, Vélez C, Prados J.

Int J Mol Sci. 2015 Jun 4;16(6):12601-15. doi: 10.3390/ijms160612601.


The C-terminal region of the RNA helicase CshA is required for the interaction with the degradosome and turnover of bulk RNA in the opportunistic pathogen Staphylococcus aureus.

Giraud C, Hausmann S, Lemeille S, Prados J, Redder P, Linder P.

RNA Biol. 2015;12(6):658-74. doi: 10.1080/15476286.2015.1035505.


Alterations in psychosocial health of people affected by asbestos poisoning.

Clemente M, Reig-Botella A, Prados JC.

Rev Saude Publica. 2015;49:24. English, Spanish.

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