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Items: 1 to 50 of 225

1.

MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment.

Beraldo FH, Palmer D, Memar S, Wasserman DI, Lee WV, Liang S, Creighton SD, Kolisnyk B, Cowan MF, Mels J, Masood TS, Fodor C, Al-Onaizi MA, Bartha R, Gee T, Saksida LM, Bussey TJ, Strother SS, Prado VF, Winters BD, Prado MAM.

Elife. 2019 Dec 11;8. pii: e49630. doi: 10.7554/eLife.49630. [Epub ahead of print]

2.

Thiol-based direct threat sensing by the stress-activated protein kinase Hog1.

Guerra-Moreno A, Prado MA, Ang J, Schnell HM, Micoogullari Y, Paulo JA, Finley D, Gygi SP, Hanna J.

Sci Signal. 2019 Nov 26;12(609). pii: eaaw4956. doi: 10.1126/scisignal.aaw4956.

PMID:
31772124
3.

Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co-chaperone STI1.

Lackie RE, Razzaq AR, Farhan SMK, Qiu LR, Moshitzky G, Beraldo FH, Lopes MH, Maciejewski A, Gros R, Fan J, Choy WY, Greenberg DS, Martins VR, Duennwald ML, Lerch JP, Soreq H, Prado VF, Prado MAM.

J Neurochem. 2019 Sep 28. doi: 10.1111/jnc.14882. [Epub ahead of print]

PMID:
31562773
4.

Evaluation of the neuromuscular junction in a middle-aged mouse model of congenital myasthenic syndrome.

Leite Schetino LP, de Castro Fonseca M, Magalhães Gomes MPS, Costa Valadão PA, de Camargo WL, Rodrigues HA, Andrade JN, Arantes-Costa FM, Naves LA, Prado CM, Prado VF, Prado MAM, Guatimosim C.

Muscle Nerve. 2019 Dec;60(6):790-800. doi: 10.1002/mus.26710. Epub 2019 Oct 23.

PMID:
31531871
5.

Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation.

Lehner KR, Silverman HA, Addorisio ME, Roy A, Al-Onaizi MA, Levine Y, Olofsson PS, Chavan SS, Gros R, Nathanson NM, Al-Abed Y, Metz CN, Prado VF, Prado MAM, Tracey KJ, Pavlov VA.

Front Immunol. 2019 Apr 2;10:585. doi: 10.3389/fimmu.2019.00585. eCollection 2019.

6.

Selective decrease of cholinergic signaling from pedunculopontine and laterodorsal tegmental nuclei has little impact on cognition but markedly increases susceptibility to stress.

Janickova H, Kljakic O, Rosborough K, Raulic S, Matovic S, Gros R, Saksida LM, Bussey TJ, Inoue W, Prado VF, Prado MAM.

FASEB J. 2019 Jun;33(6):7018-7036. doi: 10.1096/fj.201802108R. Epub 2019 Mar 11.

PMID:
30857416
7.

The Proteasome and Its Network: Engineering for Adaptability.

Finley D, Prado MA.

Cold Spring Harb Perspect Biol. 2019 Mar 4. pii: a033985. doi: 10.1101/cshperspect.a033985. [Epub ahead of print]

PMID:
30833452
8.

Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer's Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [68Ga]Ga-TC3-OGDOTA.

Ostapchenko VG, Snir J, Suchy M, Fan J, Cobb MR, Chronik BA, Kovacs M, Prado VF, Hudson RHE, Pasternak SH, Prado MAM, Bartha R.

Contrast Media Mol Imaging. 2019 Jan 14;2019:6403274. doi: 10.1155/2019/6403274. eCollection 2019.

9.

Dissociable cognitive impairments in two strains of transgenic Alzheimer's disease mice revealed by a battery of object-based tests.

Creighton SD, Mendell AL, Palmer D, Kalisch BE, MacLusky NJ, Prado VF, Prado MAM, Winters BD.

Sci Rep. 2019 Jan 11;9(1):57. doi: 10.1038/s41598-018-37312-0.

10.

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.

Lourenco MV, Frozza RL, de Freitas GB, Zhang H, Kincheski GC, Ribeiro FC, Gonçalves RA, Clarke JR, Beckman D, Staniszewski A, Berman H, Guerra LA, Forny-Germano L, Meier S, Wilcock DM, de Souza JM, Alves-Leon S, Prado VF, Prado MAM, Abisambra JF, Tovar-Moll F, Mattos P, Arancio O, Ferreira ST, De Felice FG.

Nat Med. 2019 Jan;25(1):165-175. doi: 10.1038/s41591-018-0275-4. Epub 2019 Jan 7.

11.

The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling.

Massa F, Tammaro R, Prado MA, Cesana M, Lee BH, Finley D, Franco B, Morleo M.

Hum Mol Genet. 2019 Mar 1;28(5):764-777. doi: 10.1093/hmg/ddy380.

PMID:
30388222
12.

Vesicular acetylcholine transport deficiency potentiates some inflammatory responses induced by diesel exhaust particles.

Santana FPR, Pinheiro NM, Bittencourt-Mernak MI, Perini A, Yoshizaki K, Macchione M, Saldiva PHN, Martins MA, Tibério IFLC, Prado MAM, Prado VF, Prado CM.

Ecotoxicol Environ Saf. 2019 Jan 15;167:494-504. doi: 10.1016/j.ecoenv.2018.10.005. Epub 2018 Oct 25.

PMID:
30368143
13.

Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia.

Bretones G, Álvarez MG, Arango JR, Rodríguez D, Nadeu F, Prado MA, Valdés-Mas R, Puente DA, Paulo JA, Delgado J, Villamor N, López-Guillermo A, Finley DJ, Gygi SP, Campo E, Quesada V, López-Otín C.

Blood. 2018 Nov 29;132(22):2375-2388. doi: 10.1182/blood-2017-09-804401. Epub 2018 Sep 4.

14.

Fast and slow-twitching muscles are differentially affected by reduced cholinergic transmission in mice deficient for VAChT: A mouse model for congenital myasthenia.

Magalhães-Gomes MPS, Motta-Santos D, Schetino LPL, Andrade JN, Bastos CP, Guimarães DAS, Vaughan SK, Martinelli PM, Guatimosim S, Pereira GS, Coimbra CC, Prado VF, Prado MAM, Valdez G, Guatimosim C.

Neurochem Int. 2018 Nov;120:1-12. doi: 10.1016/j.neuint.2018.07.002. Epub 2018 Jul 9.

15.

Work and Leprosy: women in their pains, struggles and toils.

Gonçalves M, Prado MARD, Silva SSD, Santos KDS, Araujo PN, Fortuna CM.

Rev Bras Enferm. 2018;71(suppl 1):660-667. doi: 10.1590/0034-7167-2017-0598. English, Portuguese.

16.

Estradiol effect on short-term object memory under hypocholinergic condition.

Pereira LM, Guimarães IM, Oliveira VEM, Bastos CP, Ribeiro FM, Prado VF, Prado MAM, Pereira GS.

Brain Res Bull. 2018 Jun;140:411-417. doi: 10.1016/j.brainresbull.2018.01.012. Epub 2018 Feb 12.

PMID:
29447857
17.

Histamine H3 Receptors Decrease Dopamine Release in the Ventral Striatum by Reducing the Activity of Striatal Cholinergic Interneurons.

Varaschin RK, Osterstock G, Ducrot C, Leino S, Bourque MJ, Prado MAM, Prado VF, Salminen O, Rannanpää Née Nuutinen S, Trudeau LE.

Neuroscience. 2018 Apr 15;376:188-203. doi: 10.1016/j.neuroscience.2018.01.027. Epub 2018 Jan 31.

PMID:
29374538
18.

Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice.

Fraile JM, Campos-Iglesias D, Rodríguez F, Astudillo A, Vilarrasa-Blasi R, Verdaguer-Dot N, Prado MA, Paulo JA, Gygi SP, Martín-Subero JI, Freije JMP, López-Otín C.

J Biol Chem. 2018 Feb 9;293(6):2183-2194. doi: 10.1074/jbc.M117.788430. Epub 2017 Dec 22.

19.

Mechanisms of neuroprotection against ischemic insult by stress-inducible phosphoprotein-1/prion protein complex.

Beraldo FH, Ostapchenko VG, Xu JZ, Di Guglielmo GM, Fan J, Nicholls PJ, Caron MG, Prado VF, Prado MAM.

J Neurochem. 2018 Apr;145(1):68-79. doi: 10.1111/jnc.14281. Epub 2018 Jan 12.

20.

Use of psychotropic medications in adults and elderly living in Campinas, São Paulo, Brazil: cross-sectional population-based study.

Prado MAMBD, Francisco PMSB, Barros MBA.

Epidemiol Serv Saude. 2017 Oct-Dec;26(4):747-758. doi: 10.5123/S1679-49742017000400007. English, Portuguese.

21.

Are there clinical signs and symptoms of infection to indicate the presence of multidrug-resistant bacteria in venous ulcers?

Dos Santos SLV, Martins MA, do Prado MA, Soriano JV, Bachion MM.

J Vasc Nurs. 2017 Dec;35(4):178-186. doi: 10.1016/j.jvn.2017.08.001. Epub 2017 Oct 3.

PMID:
29153225
22.

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.

Boselli M, Lee BH, Robert J, Prado MA, Min SW, Cheng C, Silva MC, Seong C, Elsasser S, Hatle KM, Gahman TC, Gygi SP, Haggarty SJ, Gan L, King RW, Finley D.

J Biol Chem. 2017 Nov 24;292(47):19209-19225. doi: 10.1074/jbc.M117.815126. Epub 2017 Sep 26.

23.

Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.

Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, Finley D, Brown EJ.

Elife. 2017 Sep 21;6. pii: e26435. doi: 10.7554/eLife.26435.

24.

Preface: Cholinergic Mechanisms.

Prado MAM, Marchot P, Silman I.

J Neurochem. 2017 Aug;142 Suppl 2:3-6. doi: 10.1111/jnc.14027. Review.

25.

UBE2O remodels the proteome during terminal erythroid differentiation.

Nguyen AT, Prado MA, Schmidt PJ, Sendamarai AK, Wilson-Grady JT, Min M, Campagna DR, Tian G, Shi Y, Dederer V, Kawan M, Kuehnle N, Paulo JA, Yao Y, Weiss MJ, Justice MJ, Gygi SP, Fleming MD, Finley D.

Science. 2017 Aug 4;357(6350). pii: eaan0218. doi: 10.1126/science.aan0218.

26.

Vesicular acetylcholine transporter (VAChT) over-expression induces major modifications of striatal cholinergic interneuron morphology and function.

Janickova H, Prado VF, Prado MAM, El Mestikawy S, Bernard V.

J Neurochem. 2017 Sep;142(6):857-875. doi: 10.1111/jnc.14105. Epub 2017 Jul 11.

27.

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.

Quirós PM, Prado MA, Zamboni N, D'Amico D, Williams RW, Finley D, Gygi SP, Auwerx J.

J Cell Biol. 2017 Jul 3;216(7):2027-2045. doi: 10.1083/jcb.201702058. Epub 2017 May 31.

28.

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases.

Lackie RE, Maciejewski A, Ostapchenko VG, Marques-Lopes J, Choy WY, Duennwald ML, Prado VF, Prado MAM.

Front Neurosci. 2017 May 16;11:254. doi: 10.3389/fnins.2017.00254. eCollection 2017. Review.

29.

Characterization of phenolic compounds in chia (Salvia hispanica L.) seeds, fiber flour and oil.

Oliveira-Alves SC, Vendramini-Costa DB, Betim Cazarin CB, Maróstica Júnior MR, Borges Ferreira JP, Silva AB, Prado MA, Bronze MR.

Food Chem. 2017 Oct 1;232:295-305. doi: 10.1016/j.foodchem.2017.04.002. Epub 2017 Apr 5.

30.

Reduced Vesicular Acetylcholine Transporter favors antidepressant behaviors and modulates serotonin and dopamine in female mouse brain.

Pádua-Reis M, Aquino NS, Oliveira VEM, Szawka RE, Prado MAM, Prado VF, Pereira GS.

Behav Brain Res. 2017 Jul 14;330:127-132. doi: 10.1016/j.bbr.2017.04.049. Epub 2017 Apr 28.

PMID:
28461009
31.

Cholinergic/glutamatergic co-transmission in striatal cholinergic interneurons: new mechanisms regulating striatal computation.

Kljakic O, Janickova H, Prado VF, Prado MAM.

J Neurochem. 2017 Aug;142 Suppl 2:90-102. doi: 10.1111/jnc.14003. Epub 2017 Apr 18. Review.

32.

Molecular basis for the interaction between stress-inducible phosphoprotein 1 (STIP1) and S100A1.

Maciejewski A, Prado VF, Prado MAM, Choy WY.

Biochem J. 2017 May 16;474(11):1853-1866. doi: 10.1042/BCJ20161055.

PMID:
28408431
33.

Synthetic triterpenoids inhibit GSK3β activity and localization and affect focal adhesions and cell migration.

To C, Roy A, Chan E, Prado MAM, Di Guglielmo GM.

Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1274-1284. doi: 10.1016/j.bbamcr.2017.03.012. Epub 2017 Mar 30.

34.

Glibenclamide treatment blocks metabolic dysfunctions and improves vagal activity in monosodium glutamate-obese male rats.

Franco CCS, Prates KV, Previate C, Moraes AMP, Matiusso CCI, Miranda RA, de Oliveira JC, Tófolo LP, Martins IP, Barella LF, Ribeiro TA, Malta A, Pavanello A, Francisco FA, Gomes RM, Alves VS, Moreira VM, Rigo KP, Almeida DL, de Sant Anna JR, Prado MAAC, Mathias PCF.

Endocrine. 2017 May;56(2):346-356. doi: 10.1007/s12020-017-1263-z. Epub 2017 Feb 23.

PMID:
28233096
35.

Mosaic expression of Atrx in the mouse central nervous system causes memory deficits.

Tamming RJ, Siu JR, Jiang Y, Prado MA, Beier F, Bérubé NG.

Dis Model Mech. 2017 Feb 1;10(2):119-126. doi: 10.1242/dmm.027482. Epub 2017 Jan 12.

36.

Deletion of the vesicular acetylcholine transporter from pedunculopontine/laterodorsal tegmental neurons modifies gait.

Janickova H, Rosborough K, Al-Onaizi M, Kljakic O, Guzman MS, Gros R, Prado MA, Prado VF.

J Neurochem. 2017 Mar;140(5):787-798. doi: 10.1111/jnc.13910. Epub 2017 Jan 6.

37.

Use of prescription drugs and self-medication among men.

Prado MA, Francisco PM, Bastos TF, Barros MB.

Rev Bras Epidemiol. 2016 Jul-Sep;19(3):594-608. doi: 10.1590/1980-5497201600030010. Portuguese, English.

38.

Diabetes in the elderly: drug use and the risk of drug interaction.

Prado MA, Francisco PM, Barros MB.

Cien Saude Colet. 2016 Nov;21(11):3447-3458. doi: 10.1590/1413-812320152111.24462015. Portuguese, English.

39.

Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.

Rose CM, Isasa M, Ordureau A, Prado MA, Beausoleil SA, Jedrychowski MP, Finley DJ, Harper JW, Gygi SP.

Cell Syst. 2016 Oct 26;3(4):395-403.e4. doi: 10.1016/j.cels.2016.08.009. Epub 2016 Sep 22.

40.

Acute lung injury is reduced by the α7nAChR agonist PNU-282987 through changes in the macrophage profile.

Pinheiro NM, Santana FP, Almeida RR, Guerreiro M, Martins MA, Caperuto LC, Câmara NO, Wensing LA, Prado VF, Tibério IF, Prado MA, Prado CM.

FASEB J. 2017 Jan;31(1):320-332. doi: 10.1096/fj.201600431R. Epub 2016 Oct 11.

PMID:
27729414
41.

VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions.

Sugita S, Fleming LL, Wood C, Vaughan SK, Gomes MP, Camargo W, Naves LA, Prado VF, Prado MA, Guatimosim C, Valdez G.

Skelet Muscle. 2016 Oct 5;6:31. eCollection 2016.

42.

Cholinergic circuits in cognitive flexibility.

Prado VF, Janickova H, Al-Onaizi MA, Prado MA.

Neuroscience. 2017 Mar 14;345:130-141. doi: 10.1016/j.neuroscience.2016.09.013. Epub 2016 Sep 15. Review.

PMID:
27641830
43.

Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex.

Beraldo FH, Ostapchenko VG, Caetano FA, Guimaraes AL, Ferretti GD, Daude N, Bertram L, Nogueira KO, Silva JL, Westaway D, Cashman NR, Martins VR, Prado VF, Prado MA.

J Biol Chem. 2016 Oct 14;291(42):21945-21955. Epub 2016 Aug 25.

44.

Reduced expression of VAChT increases renal fibrosis.

Silva RC, Terra FF, Guise YF, Prado MA, Prado VF, Hiyane MI, Costa Malheiros DM, Prado CM, Camara NO, Braga TT.

Pathophysiology. 2016 Sep;23(3):229-36. doi: 10.1016/j.pathophys.2016.07.002. Epub 2016 Aug 10.

PMID:
27524473
45.

Commemorating John F. MacDonald and the Art of Being a Mentor.

Jackson MF, Prado VF, Prado MA.

Can J Neurol Sci. 2016 Sep;43(5):735-44. doi: 10.1017/cjn.2016.272. Epub 2016 Aug 4. Review.

PMID:
27488619
46.

Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.

Kolisnyk B, Al-Onaizi M, Soreq L, Barbash S, Bekenstein U, Haberman N, Hanin G, Kish MT, Souza da Silva J, Fahnestock M, Ule J, Soreq H, Prado VF, Prado MAM.

Cereb Cortex. 2017 Jul 1;27(7):3553-3567. doi: 10.1093/cercor/bhw177.

PMID:
27312991
47.

Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors.

Kolisnyk B, Al-Onaizi MA, Xu J, Parfitt GM, Ostapchenko VG, Hanin G, Soreq H, Prado MA, Prado VF.

J Neurosci. 2016 Jun 8;36(23):6287-96. doi: 10.1523/JNEUROSCI.4614-15.2016.

48.

Mice deficient for striatal Vesicular Acetylcholine Transporter (VAChT) display impaired short-term but normal long-term object recognition memory.

Palmer D, Creighton S, Prado VF, Prado MAM, Choleris E, Winters BD.

Behav Brain Res. 2016 Sep 15;311:267-278. doi: 10.1016/j.bbr.2016.05.050. Epub 2016 May 24.

PMID:
27233822
49.

Domains of STIP1 responsible for regulating PrPC-dependent amyloid-β oligomer toxicity.

Maciejewski A, Ostapchenko VG, Beraldo FH, Prado VF, Prado MA, Choy WY.

Biochem J. 2016 Jul 15;473(14):2119-30. doi: 10.1042/BCJ20160087. Epub 2016 May 17.

PMID:
27208175
50.

Vesicular acetylcholine transporter knock down-mice are more susceptible to inflammation, c-Fos expression and sickness behavior induced by lipopolysaccharide.

Leite HR, Oliveira-Lima OC, Pereira LM, Oliveira VEM, Prado VF, Prado MAM, Pereira GS, Massensini AR.

Brain Behav Immun. 2016 Oct;57:282-292. doi: 10.1016/j.bbi.2016.05.005. Epub 2016 May 11.

PMID:
27179819

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