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Inhibition of MAPK and STAT3-SOCS3 by Sakuranetin Attenuated Chronic Allergic Airway Inflammation in Mice.

Santana FPR, da Silva RC, Grecco SDS, Pinheiro AJMCR, Caperuto LC, Arantes-Costa FM, Claudio SR, Yoshizaki K, Macchione M, Ribeiro DA, Tibério IFLC, Lima-Neto LG, Lago JHG, Prado CM.

Mediators Inflamm. 2019 Sep 3;2019:1356356. doi: 10.1155/2019/1356356. eCollection 2019.


Post diagnosis loss of skeletal muscle, but not adipose tissue, is associated with shorter survival of patients with advanced pancreatic cancer.

Babic A, Rosenthal MH, Bamlet WR, Takahashi N, Sugimoto M, Danai LV, Morales-Oyarvide V, Khalaf N, Dunne RF, Brais LK, Welch MW, Zellers CL, Dennis C, Rifai N, Prado CM, Caan B, Sundaresan TK, Meyerhardt JA, Kulke MH, Clish CB, Ng K, Vander Heiden MG, Petersen GM, Wolpin BM.

Cancer Epidemiol Biomarkers Prev. 2019 Sep 18. pii: cebp.0370.2019. doi: 10.1158/1055-9965.EPI-19-0370. [Epub ahead of print]


Evaluation of the neuromuscular junction in a middle-aged mouse model of congenital myasthenic syndrome.

Leite Schetino LP, de Castro Fonseca M, Gomes MPSM, Valadão PAC, de Camargo WL, Rodrigues HA, Andrade JN, Arantes-Costa FM, Naves LA, Prado CM, Prado VF, Prado MAM, Guatimosim C.

Muscle Nerve. 2019 Sep 18. doi: 10.1002/mus.26710. [Epub ahead of print]


Sarcopenia: A Time for Action. An SCWD Position Paper.

Bauer J, Morley JE, Schols AMWJ, Ferrucci L, Cruz-Jentoft AJ, Dent E, Baracos VE, Crawford JA, Doehner W, Heymsfield SB, Jatoi A, Kalantar-Zadeh K, Lainscak M, Landi F, Laviano A, Mancuso M, Muscaritoli M, Prado CM, Strasser F, von Haehling S, Coats AJS, Anker SD.

J Cachexia Sarcopenia Muscle. 2019 Sep 15. doi: 10.1002/jcsm.12483. [Epub ahead of print]


Effects of weight loss and sarcopenia on response to chemotherapy, quality of life, and survival.

Ryan AM, Prado CM, Sullivan ES, Power DG, Daly LE.

Nutrition. 2019 Jun 28;67-68:110539. doi: 10.1016/j.nut.2019.06.020. [Epub ahead of print]


Galloyl-Hexahydroxydiphenoyl (HHDP)-Glucose Isolated From Punica granatum L. Leaves Protects Against Lipopolysaccharide (LPS)-Induced Acute Lung Injury in BALB/c Mice.

Pinheiro AJMCR, Mendes ARS, Neves MDFJ, Prado CM, Bittencourt-Mernak MI, Santana FPR, Lago JHG, de Sá JC, da Rocha CQ, de Sousa EM, Fontes VC, Grisoto MAG, Falcai A, Lima-Neto LG.

Front Immunol. 2019 Aug 20;10:1978. doi: 10.3389/fimmu.2019.01978. eCollection 2019.


Adipose Tissue Distribution and Cardiovascular Disease Risk Among Breast Cancer Survivors.

Cespedes Feliciano EM, Chen WY, Bradshaw PT, Prado CM, Alexeeff S, Albers KB, Castillo AL, Caan BJ.

J Clin Oncol. 2019 Oct 1;37(28):2528-2536. doi: 10.1200/JCO.19.00286. Epub 2019 Aug 1.


The Association of Abdominal Adiposity with Mortality in Patients with Stage I-III Colorectal Cancer.

Brown JC, Caan BJ, Prado CM, Feliciano EMC, Xiao J, Kroenke CH, Meyerhardt JA.

J Natl Cancer Inst. 2019 Jul 29. pii: djz150. doi: 10.1093/jnci/djz150. [Epub ahead of print]


Metabolic implications of low muscle mass in the pediatric population: a critical review.

Orsso CE, Tibaes JRB, Rubin DA, Field CJ, Heymsfield SB, Prado CM, Haqq AM.

Metabolism. 2019 Oct;99:102-112. doi: 10.1016/j.metabol.2019.153949. Epub 2019 Jul 23. Review.


Accuracy of Resting Energy Expenditure Predictive Equations in Patients With Cancer.

Purcell SA, Elliott SA, Baracos VE, Chu QSC, Sawyer MB, Mourtzakis M, Easaw JC, Spratlin JL, Siervo M, Prado CM.

Nutr Clin Pract. 2019 Jul 25. doi: 10.1002/ncp.10374. [Epub ahead of print]


Patient-Generated Subjective Global Assessment and Computed Tomography in the assessment of malnutrition and sarcopenia in patients with cirrhosis: Is there any association?

Zambrano DN, Xiao J, Prado CM, Gonzalez MC.

Clin Nutr. 2019 Jun 27. pii: S0261-5614(19)30274-2. doi: 10.1016/j.clnu.2019.06.018. [Epub ahead of print]


Profiling Determinants of Resting Energy Expenditure in Colorectal Cancer.

Purcell SA, Baracos VE, Chu QSC, Sawyer MB, Severin D, Mourtzakis M, Lieffers JR, Prado CM.

Nutr Cancer. 2019 Jul 8:1-8. doi: 10.1080/01635581.2019.1635172. [Epub ahead of print]


Prevalence of sarcopenic obesity in adults with end-stage knee osteoarthritis.

Godziuk K, Prado CM, Woodhouse LJ, Forhan M.

Osteoarthritis Cartilage. 2019 Jul 2. pii: S1063-4584(19)31109-4. doi: 10.1016/j.joca.2019.05.026. [Epub ahead of print]


Total energy expenditure in patients with colorectal cancer: associations with body composition, physical activity, and energy recommendations.

Purcell SA, Elliott SA, Walter PJ, Preston T, Cai H, Skipworth RJE, Sawyer MB, Prado CM.

Am J Clin Nutr. 2019 Aug 1;110(2):367-376. doi: 10.1093/ajcn/nqz112.


American Society for Parenteral and Enteral Nutrition Clinical Guidelines: The Validity of Body Composition Assessment in Clinical Populations.

Sheean P, Gonzalez MC, Prado CM, McKeever L, Hall AM, Braunschweig CA.

JPEN J Parenter Enteral Nutr. 2019 Jun 19. doi: 10.1002/jpen.1669. [Epub ahead of print]


Body Composition and Cardiovascular Events in Patients With Colorectal Cancer: A Population-Based Retrospective Cohort Study.

Brown JC, Caan BJ, Prado CM, Weltzien E, Xiao J, Cespedes Feliciano EM, Kroenke CH, Meyerhardt JA.

JAMA Oncol. 2019 Jul 1;5(7):967-972. doi: 10.1001/jamaoncol.2019.0695.


Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study.

Rees JL, Chang CR, François ME, Marcotte-Chénard A, Fontvieille A, Klaprat ND, Dyck RA, Funk DR, Snydmiller G, Bastell K, Godkin FE, Dubé MC, Riesco E, McGavock JM, Yardley JE, Sigal RJ, Gibala MJ, Weisnagel SJ, Prado CM, Jung M, Manders R, Lee T, Singer J, Boulé NG, Little JP.

Acta Diabetol. 2019 Jul;56(7):755-765. doi: 10.1007/s00592-019-01358-x. Epub 2019 May 15.


The influence of energy metabolism on postpartum weight retention.

Pereira LCR, Elliott SA, McCargar LJ, Bell RC, Vu K, Bell G, Robson PJ, Prado CM; ENRICH Study Team.

Am J Clin Nutr. 2019 Jun 1;109(6):1588-1599. doi: 10.1093/ajcn/nqy389.


Lean mass declines consistently over 10 years in people living with HIV on antiretroviral therapy, with patterns differing by sex.

Debroy P, Lake JE, Sim M, Erlandson KM, Falutz J, Prado CM, Brown TT, Guaraldi G; Modena HIV Metabolic Cohort Team.

Antivir Ther. 2019 Apr 29. doi: 10.3851/IMP3312. [Epub ahead of print]


Low muscle mass and strength in pediatrics patients: Why should we care?

Orsso CE, Tibaes JRB, Oliveira CLP, Rubin DA, Field CJ, Heymsfield SB, Prado CM, Haqq AM.

Clin Nutr. 2019 Oct;38(5):2002-2015. doi: 10.1016/j.clnu.2019.04.012. Epub 2019 Apr 18. Review.


Adipose Tissue Distribution and Survival Among Women with Nonmetastatic Breast Cancer.

Bradshaw PT, Cespedes Feliciano EM, Prado CM, Alexeeff S, Albers KB, Chen WY, Caan BJ.

Obesity (Silver Spring). 2019 Jun;27(6):997-1004. doi: 10.1002/oby.22458. Epub 2019 Apr 25.


iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice.

Prado CM, Righetti RF, Lopes FDTQDS, Leick EA, Arantes-Costa FM, de Almeida FM, Saldiva PHN, Mauad T, Tibério IFLC, Martins MA.

Pulm Med. 2019 Mar 11;2019:4781528. doi: 10.1155/2019/4781528. eCollection 2019.


Extracellular Matrix Component Remodeling in Respiratory Diseases: What Has Been Found in Clinical and Experimental Studies?

Ito JT, Lourenço JD, Righetti RF, Tibério IFLC, Prado CM, Lopes FDTQS.

Cells. 2019 Apr 11;8(4). pii: E342. doi: 10.3390/cells8040342. Review.


Determinants of change in resting energy expenditure in patients with stage III/IV colorectal cancer.

Purcell SA, Wallengren O, Baracos VE, Lundholm K, Iresjö BM, Chu QSC, Ghosh SS, Prado CM.

Clin Nutr. 2019 Mar 30. pii: S0261-5614(19)30135-9. doi: 10.1016/j.clnu.2018.12.038. [Epub ahead of print]


Microenvironmental stimuli induce different macrophage polarizations in experimental models of emphysema.

Kohler JB, Cervilha DAB, Riani Moreira A, Santana FR, Farias TM, Alonso Vale MIC, Martins MA, Prado CM, Tibério IC, Ito JT, Lopes FDTQDS.

Biol Open. 2019 Apr 26;8(4). pii: bio040808. doi: 10.1242/bio.040808.


Higher-protein intake and physical activity are associated with healthier body composition and cardiometabolic health in Hispanic adults.

Brown AF, Prado CM, Ghosh S, Leonard SM, Arciero PJ, Tucker KL, Ormsbee MJ.

Clin Nutr ESPEN. 2019 Apr;30:145-151. doi: 10.1016/j.clnesp.2019.01.002. Epub 2019 Jan 25.


The association of medical and demographic characteristics with sarcopenia and low muscle radiodensity in patients with nonmetastatic colorectal cancer.

Xiao J, Caan BJ, Cespedes Feliciano EM, Meyerhardt JA, Kroenke CH, Baracos VE, Weltzien E, Kwan ML, Alexeeff SE, Castillo AL, Prado CM.

Am J Clin Nutr. 2019 Mar 1;109(3):615-625. doi: 10.1093/ajcn/nqy328.


The use of whole body calorimetry to compare measured versus predicted energy expenditure in postpartum women.

Pereira LCR, Purcell SA, Elliott SA, McCargar LJ, Bell RC, Robson PJ, Prado CM; ENRICH Study Team.

Am J Clin Nutr. 2019 Mar 1;109(3):554-565. doi: 10.1093/ajcn/nqy312.


Progressive increases in fat mass occur in adults living with HIV on antiretroviral therapy, but patterns differ by sex and anatomic depot.

Debroy P, Sim M, Erlandson KM, Falutz J, Prado CM, Brown TT, Guaraldi G, Lake JE.

J Antimicrob Chemother. 2019 Apr 1;74(4):1028-1034. doi: 10.1093/jac/dky551.


Relationship between Sarcopenia and mTOR Pathway in Patients with Colorectal Cancer: Preliminary Report.

Maurício SF, de Vasconcelos Generoso S, Leandro Marciano Vieira É, Xiao J, Prado CM, Gonzalez MC, Correia MITD.

Nutr Cancer. 2019;71(1):172-177. doi: 10.1080/01635581.2018.1540716. Epub 2019 Jan 20.


Obestatin and adropin in Prader-Willi syndrome and nonsyndromic obesity: Associations with weight, BMI-z, and HOMA-IR.

Orsso CE, Butler AA, Muehlbauer MJ, Cui HN, Rubin DA, Pakseresht M, Butler MG, Prado CM, Freemark M, Haqq AM.

Pediatr Obes. 2019 May;14(5):e12493. doi: 10.1111/ijpo.12493. Epub 2018 Dec 27.


The Underappreciated Role of Low Muscle Mass in the Management of Malnutrition.

Deutz NEP, Ashurst I, Ballesteros MD, Bear DE, Cruz-Jentoft AJ, Genton L, Landi F, Laviano A, Norman K, Prado CM.

J Am Med Dir Assoc. 2019 Jan;20(1):22-27. doi: 10.1016/j.jamda.2018.11.021.


A plant proteinase inhibitor from Enterolobium contortisiliquum attenuates airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma.

Rodrigues APD, Bortolozzo ASS, Arantes-Costa FM, Saraiva-Romanholo BM, de Souza FCR, Brüggemann TR, Santana FPR, de Brito MV, Bonturi CR, Nunes NNDS, Prado CM, Leick EA, Oliva MLV, Martins MA, Righetti RF, Tibério IFLC.

Histol Histopathol. 2019 May;34(5):537-552. doi: 10.14670/HH-18-059. Epub 2018 Nov 8.


Poor Physical Function as a Marker of Sarcopenia in Adults with Class II/III Obesity.

Johnson Stoklossa CA, Ghosh SS, Forhan M, Sharma AM, Terada T, Siervo M, Baracos VE, Padwal RS, Hung PA, Sawyer MB, Maia YL, Prado CM.

Curr Dev Nutr. 2017 Dec 18;2(3):nzx008. doi: 10.3945/cdn.117.001743. eCollection 2018 Mar.


Vesicular acetylcholine transport deficiency potentiates some inflammatory responses induced by diesel exhaust particles.

Santana FPR, Pinheiro NM, Bittencourt-Mernak MI, Perini A, Yoshizaki K, Macchione M, Saldiva PHN, Martins MA, Tibério IFLC, Prado MAM, Prado VF, Prado CM.

Ecotoxicol Environ Saf. 2019 Jan 15;167:494-504. doi: 10.1016/j.ecoenv.2018.10.005. Epub 2018 Oct 25.


The Plant Proteinase Inhibitor CrataBL Plays a Role in Controlling Asthma Response in Mice.

Bortolozzo ASS, Rodrigues APD, Arantes-Costa FM, Saraiva-Romanholo BM, de Souza FCR, Brüggemann TR, de Brito MV, Ferreira RDS, Correia MTDS, Paiva PMG, Prado CM, Leick EA, Oliva MLV, Martins MA, Ruiz-Schutz VC, Righetti RF, Tibério IFLC.

Biomed Res Int. 2018 Oct 1;2018:9274817. doi: 10.1155/2018/9274817. eCollection 2018.


Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice.

Righetti RF, Dos Santos TM, Camargo LDN, Aristóteles LRCRB, Fukuzaki S, de Souza FCR, Santana FPR, de Agrela MVR, Cruz MM, Alonso-Vale MIC, Genaro IS, Saraiva-Romanholo BM, Leick EA, Martins MA, Prado CM, Tibério IFLC.

Front Pharmacol. 2018 Oct 4;9:1021. doi: 10.3389/fphar.2018.01021. eCollection 2018.


Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma.

Dos Santos TM, Righetti RF, Camargo LDN, Saraiva-Romanholo BM, Aristoteles LRCRB, de Souza FCR, Fukuzaki S, Alonso-Vale MIC, Cruz MM, Prado CM, Leick EA, Martins MA, Tibério IFLC.

Front Physiol. 2018 Sep 5;9:1183. doi: 10.3389/fphys.2018.01183. eCollection 2018.


Trajectory and determinants of change in lean soft tissue over the postpartum period.

Elliott SA, Pereira LCR, McCargar LJ, Prado CM, Bell RC; ENRICH Study Team.

Br J Nutr. 2019 May;121(10):1137-1145. doi: 10.1017/S0007114518002015. Epub 2018 Sep 4.


Implications of low muscle mass across the continuum of care: a narrative review.

Prado CM, Purcell SA, Alish C, Pereira SL, Deutz NE, Heyland DK, Goodpaster BH, Tappenden KA, Heymsfield SB.

Ann Med. 2018 Dec;50(8):675-693. doi: 10.1080/07853890.2018.1511918. Epub 2018 Sep 12.


The impact of sarcopenic obesity on knee and hip osteoarthritis: a scoping review.

Godziuk K, Prado CM, Woodhouse LJ, Forhan M.

BMC Musculoskelet Disord. 2018 Jul 28;19(1):271. doi: 10.1186/s12891-018-2175-7. Review.


Changes in Energy Metabolism from Prepregnancy to Postpartum: A Case Report.

Pereira LCR, Elliott SA, McCargar LJ, Bell RC, Prado CM.

Can J Diet Pract Res. 2018 Nov 1;79(4):191-195. doi: 10.3148/cjdpr-2018-016. Epub 2018 Jul 16.


Are Canadian protein and physical activity guidelines optimal for sarcopenia prevention in older adults?

Oliveira CLP, Dionne IJ, Prado CM.

Appl Physiol Nutr Metab. 2018 Dec;43(12):1215-1223. doi: 10.1139/apnm-2018-0141. Epub 2018 Jul 10.


Altered exocrine function can drive adipose wasting in early pancreatic cancer.

Danai LV, Babic A, Rosenthal MH, Dennstedt EA, Muir A, Lien EC, Mayers JR, Tai K, Lau AN, Jones-Sali P, Prado CM, Petersen GM, Takahashi N, Sugimoto M, Yeh JJ, Lopez N, Bardeesy N, Fernandez-Del Castillo C, Liss AS, Koong AC, Bui J, Yuan C, Welch MW, Brais LK, Kulke MH, Dennis C, Clish CB, Wolpin BM, Vander Heiden MG.

Nature. 2018 Jun;558(7711):600-604. doi: 10.1038/s41586-018-0235-7. Epub 2018 Jun 20.


The comparative efficacy of renin-angiotensin system blockers in schistosomal hepatic fibrosis.

Parreira NA, Ramalho FS, Augusto MJ, Silva DM, Prado CM, Elias Júnior J, Rodrigues V, Ramalho LNZ.

Exp Parasitol. 2018 Aug;191:9-18. doi: 10.1016/j.exppara.2018.05.004. Epub 2018 Jun 8.


Accuracy of a Portable Indirect Calorimeter for Measuring Resting Energy Expenditure in Individuals With Cancer.

Purcell SA, Elliott SA, Ryan AM, Sawyer MB, Prado CM.

JPEN J Parenter Enteral Nutr. 2019 Jan;43(1):145-151. doi: 10.1002/jpen.1310. Epub 2018 Jun 5.


Muscle radiodensity and mortality in patients with colorectal cancer.

Kroenke CH, Prado CM, Meyerhardt JA, Weltzien EK, Xiao J, Cespedes Feliciano EM, Caan BJ.

Cancer. 2018 Jul 15;124(14):3008-3015. doi: 10.1002/cncr.31405. Epub 2018 May 24.


The use of computed tomography images as a prognostic marker in critically ill cancer patients.

Toledo DO, Carvalho AM, Oliveira AMRR, Toloi JM, Silva AC, Francisco de Mattos Farah J, Prado CM, Silva JM Jr.

Clin Nutr ESPEN. 2018 Jun;25:114-120. doi: 10.1016/j.clnesp.2018.03.122. Epub 2018 Apr 4.


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