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Items: 12


Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.

Prukova D, Andera L, Nahacka Z, Karolova J, Svaton M, Klanova M, Havranek O, Soukup J, Svobodova K, Zemanova Z, Tuskova D, Pokorna E, Helman K, Forsterova K, Pacheco-Blanco M, Vockova P, Berkova A, Fronkova E, Trneny M, Klener P.

Clin Cancer Res. 2019 Jul 15;25(14):4455-4465. doi: 10.1158/1078-0432.CCR-18-3275. Epub 2019 Apr 19.


Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement.

Maswabi BC, Molinsky J, Savvulidi F, Zikmund T, Prukova D, Tuskova D, Klanova M, Vockova P, Lateckova L, Sefc L, Zivny J, Trneny M, Klener P.

Haematologica. 2017 Apr;102(4):e152-e155. doi: 10.3324/haematol.2016.151571. Epub 2017 Jan 5. No abstract available.


Mantle cell lymphoma-variant Richter syndrome: Detailed molecular-cytogenetic and backtracking analysis reveals slow evolution of a pre-MCL clone in parallel with CLL over several years.

Klener P, Fronkova E, Berkova A, Jaksa R, Lhotska H, Forsterova K, Soukup J, Kulvait V, Vargova J, Fiser K, Prukova D, Alam M, Calvin Lenyeletse Maswabi B, Michalova K, Zemanova Z, Jancuskova T, Pekova S, Trneny M.

Int J Cancer. 2016 Nov 15;139(10):2252-60. doi: 10.1002/ijc.30263. Epub 2016 Aug 2.


Lenalidomide enhances antitumor functions of chimeric antigen receptor modified T cells.

Otáhal P, Průková D, Král V, Fabry M, Vočková P, Latečková L, Trněný M, Klener P.

Oncoimmunology. 2015 Dec 3;5(4):e1115940. eCollection 2016 Apr.


Significantly higher numbers of proB cells in healthy Caucasians compared to Asians: Is there association with incidence of CLL?

Molinsky J, Maswabi B, Prukova D, Klanova M, Vockova P, Zikmund T, Savvulidi F, Alam M, Sefc L, Vokurka M, Obrtlikova P, Trneny M, Klener P Jr.

Blood Cells Mol Dis. 2016 Mar;57:118-9. doi: 10.1016/j.bcmd.2015.12.001. Epub 2015 Dec 2. No abstract available.


Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma.

Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, Prukova D, Vejmelkova D, Jaksa R, Helman K, Vockova P, Lateckova L, Molinsky J, Maswabi BC, Alam M, Kodet R, Pytlik R, Trneny M, Klener P.

Clin Cancer Res. 2016 Mar 1;22(5):1138-49. doi: 10.1158/1078-0432.CCR-15-1191. Epub 2015 Oct 14. Erratum in: Clin Cancer Res. 2016 Aug 1;22(15):3984.


Transgenic reporter mice with promoter region of murine LRAT specifically marks lens and meiosis spermatocytes.

Prukova D, Ileninova Z, Antosova B, Kasparek P, Gregor M, Sedlacek R.

Physiol Res. 2015;64(2):247-54. Epub 2014 Oct 15.


Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research.

Klanova M, Soukup T, Jaksa R, Molinsky J, Lateckova L, Maswabi BC, Prukova D, Brezinova J, Michalova K, Vockova P, Hernandez-Ilizaliturri F, Kulvait V, Zivny J, Vokurka M, Necas E, Trneny M, Klener P.

Lab Invest. 2014 Jul;94(7):806-17. doi: 10.1038/labinvest.2014.61. Epub 2014 May 26.


Industasis, a promotion of tumor formation by nontumorigenic stray cells.

Pajer P, Karafiát V, Pecenka V, Pruková D, Dudlová J, Plachy J, Kasparová P, Dvorák M.

Cancer Res. 2009 Jun 1;69(11):4605-12. doi: 10.1158/0008-5472.CAN-08-4636.


A new allelic discrimination assay using locked nucleic acid-modified nucleotides (LNA) probes for detection of JAK2 V617F mutation.

Marková J, Průková D, Volková Z, Schwarz J.

Leuk Lymphoma. 2007 Mar;48(3):636-9. No abstract available.


Differences in pathogenicity among strains of the same or different avian leukosis virus subgroups.

Průková D, Vernerová Z, Pilcík T, Stepanets V, Indrová M, Geryk J, Plachý J, Hejnar J, Svoboda J.

Avian Pathol. 2007 Feb;36(1):15-27.


Identification of potential human oncogenes by mapping the common viral integration sites in avian nephroblastoma.

Pajer P, Pecenka V, Králová J, Karafiát V, Průková D, Zemanová Z, Kodet R, Dvorák M.

Cancer Res. 2006 Jan 1;66(1):78-86.

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