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Items: 1 to 20 of 322

1.

Protective effects of 18β-glycyrrhetinic acid on pulmonary arterial hypertension via regulation of Rho A/Rho kinsase pathway.

Zhang M, Chang Z, Zhang P, Jing Z, Yan L, Feng J, Hu Z, Xu Q, Zhou W, Ma P, Hao Y, Zhou R.

Chem Biol Interact. 2019 Sep 25;311:108749. doi: 10.1016/j.cbi.2019.108749. Epub 2019 Jul 17.

PMID:
31325423
2.

Genomic signatures of high-altitude adaptation in Ethiopian sheep populations.

Edea Z, Dadi H, Dessie T, Kim KS.

Genes Genomics. 2019 Aug;41(8):973-981. doi: 10.1007/s13258-019-00820-y. Epub 2019 May 22.

PMID:
31119684
3.

Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.

Addison WN, Pellicelli M, St-Arnaud R.

J Biol Chem. 2019 May 17;294(20):8184-8196. doi: 10.1074/jbc.RA118.006920. Epub 2019 Apr 4.

PMID:
30948508
4.

A comparison of adult rhabdomyosarcoma and high-grade neuroendocrine carcinoma of the urinary bladder reveals novel PPP1R12A fusions in rhabdomyosarcoma.

Gupta S, Sosa CP, Kosari F, Folpe A, Bhinge KN, Yang L, Agahi A, Johnson SH, Frank I, Boorjian SA, Hansel DE, Al-Ahmadie HA, Reuter VE, Vasmatzis G, Jimenez RE, Herrera-Hernandez L, Cheville JC.

Hum Pathol. 2019 Jun;88:48-59. doi: 10.1016/j.humpath.2019.03.007. Epub 2019 Apr 1.

PMID:
30946934
5.

A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling.

Zheng X, Chen L, Zhou Y, Wang Q, Zheng Z, Xu B, Wu C, Zhou Q, Hu W, Wu C, Jiang J.

Mol Cancer. 2019 Mar 29;18(1):47. doi: 10.1186/s12943-019-1010-6.

6.

α1D-adrenoceptor involves the relaxation effect of farrerol in rat aortic vascular smooth muscle cells.

Qin X, Hou X, Zhang K, Li Q.

Eur J Pharmacol. 2019 Jun 15;853:169-183. doi: 10.1016/j.ejphar.2019.02.012. Epub 2019 Feb 12.

PMID:
30768980
7.

Statin treatment before stroke reduces pro-inflammatory cytokine levels after stroke.

Schultz NEØ, Hasseldam H, Rasmussen RS, Vindegaard N, McWilliam O, Iversen HK, Johansen FF.

Neurol Res. 2019 Apr;41(4):289-297. doi: 10.1080/01616412.2018.1558000. Epub 2018 Dec 21.

PMID:
30574850
8.

Genetic Inactivation of Chlamydia trachomatis Inclusion Membrane Protein CT228 Alters MYPT1 Recruitment, Extrusion Production, and Longevity of Infection.

Shaw JH, Key CE, Snider TA, Sah P, Shaw EI, Fisher DJ, Lutter EI.

Front Cell Infect Microbiol. 2018 Nov 30;8:415. doi: 10.3389/fcimb.2018.00415. eCollection 2018.

9.

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.

Angulo-Urarte A, Casado P, Castillo SD, Kobialka P, Kotini MP, Figueiredo AM, Castel P, Rajeeve V, Milà-Guasch M, Millan J, Wiesner C, Serra H, Muixi L, Casanovas O, Viñals F, Affolter M, Gerhardt H, Huveneers S, Belting HG, Cutillas PR, Graupera M.

Nat Commun. 2018 Nov 16;9(1):4826. doi: 10.1038/s41467-018-07172-3.

10.

MYPT1 is targeted by miR-145 inhibiting viability, migration and invasion in 2D and 3D HeLa cultures.

González-Torres A, Bañuelos-Villegas EG, Martínez-Acuña N, Sulpice E, Gidrol X, Alvarez-Salas LM.

Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):348-354. doi: 10.1016/j.bbrc.2018.11.039. Epub 2018 Nov 14.

PMID:
30446228
11.

Colchicine reduces platelet aggregation by modulating cytoskeleton rearrangement via inhibition of cofilin and LIM domain kinase 1.

Cimmino G, Tarallo R, Conte S, Morello A, Pellegrino G, Loffredo FS, Calì G, De Luca N, Golino P, Trimarco B, Cirillo P.

Vascul Pharmacol. 2018 Dec;111:62-70. doi: 10.1016/j.vph.2018.09.004. Epub 2018 Oct 1.

PMID:
30287213
12.

A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma.

Birch JL, Strathdee K, Gilmour L, Vallatos A, McDonald L, Kouzeli A, Vasan R, Qaisi AH, Croft DR, Crighton D, Gill K, Gray CH, Konczal J, Mezna M, McArthur D, Schüttelkopf AW, McConnell P, Sime M, Holmes WM, Bower J, McKinnon HJ, Drysdale M, Olson MF, Chalmers AJ.

Cancer Res. 2018 Nov 15;78(22):6509-6522. doi: 10.1158/0008-5472.CAN-18-1697. Epub 2018 Oct 2.

PMID:
30279244
13.

Oxidative stress and the altered reaction to it in Fabry disease: A possible target for cardiovascular-renal remodeling?

Ravarotto V, Carraro G, Pagnin E, Bertoldi G, Simioni F, Maiolino G, Martinato M, Landini L, Davis PA, Calò LA.

PLoS One. 2018 Sep 27;13(9):e0204618. doi: 10.1371/journal.pone.0204618. eCollection 2018.

14.

Notch signaling regulates arterial vasoreactivity through opposing functions of Jagged1 and Dll4 in the vessel wall.

Basu S, Barbur I, Calderon A, Banerjee S, Proweller A.

Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1835-H1850. doi: 10.1152/ajpheart.00293.2018. Epub 2018 Aug 31.

PMID:
30168730
15.

Proinflammatory/profibrotic effects of aldosterone in Gitelman's syndrome, a human model opposite to hypertension.

Ravarotto V, Simioni F, Sabbadin C, Pagnin E, Maiolino G, Armanini D, Calò LA.

J Endocrinol Invest. 2019 May;42(5):521-526. doi: 10.1007/s40618-018-0942-9. Epub 2018 Aug 22.

PMID:
30136149
16.

Myosin phosphatase: Unexpected functions of a long-known enzyme.

Kiss A, Erdődi F, Lontay B.

Biochim Biophys Acta Mol Cell Res. 2019 Jan;1866(1):2-15. doi: 10.1016/j.bbamcr.2018.07.023. Epub 2018 Aug 2. Review.

PMID:
30076859
17.

Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin.

Horváth D, Sipos A, Major E, Kónya Z, Bátori R, Dedinszki D, Szöll Si A, Tamás I, Iván J, Kiss A, Erd di F, Lontay B.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3268-3280. doi: 10.1016/j.bbadis.2018.07.013. Epub 2018 Jul 19.

18.

Effects of ripasudil, a ROCK inhibitor, on retinal edema and nonperfusion area in a retinal vein occlusion murine model.

Hida Y, Nakamura S, Nishinaka A, Inoue Y, Shimazawa M, Hara H.

J Pharmacol Sci. 2018 Jun;137(2):129-136. doi: 10.1016/j.jphs.2018.06.010. Epub 2018 Jun 19.

19.

Decreased Expression of MYPT1 Contributes to Tumor Angiogenesis and Poor Patient Prognosis in Human Prostate Cancer.

Liang Y, Zhuo Y, Lin Z, Jiang F, Dai Q, Lu J, Dong W, Zhu X, Han Z, Zhong W.

Curr Mol Med. 2018;18(2):100-108. doi: 10.2174/1566524018666180705111342.

20.

Paeoniflorin inhibits Rho kinase activation in joint synovial tissues of rats with collagen-induced rheumatoid arthritis.

Zhai W, Ma Z, Wang W, Song L, Yi J.

Biomed Pharmacother. 2018 Oct;106:255-259. doi: 10.1016/j.biopha.2018.06.130. Epub 2018 Jun 28.

PMID:
29966968

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