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Items: 1 to 50 of 136

1.

Determination of the steroid profile in alternative matrices by liquid chromatography tandem mass spectrometry.

Gomez-Gomez A, Miranda J, Feixas G, Arranz Betegon A, Crispi F, Gratacós E, Pozo OJ.

J Steroid Biochem Mol Biol. 2019 Nov 4:105520. doi: 10.1016/j.jsbmb.2019.105520. [Epub ahead of print]

PMID:
31698034
2.

Dose-Response Pharmacological Study of Mephedrone and Its Metabolites: Pharmacokinetics, Serotoninergic Effects, and Impact of CYP2D6 Genetic Variation.

Olesti E, Farré M, Carbó ML, Papaseit E, Perez-Mañá C, Torrens M, Yubero-Lahoz S, Pujadas M, Pozo ÓJ, de la Torre R.

Clin Pharmacol Ther. 2019 Sep;106(3):596-604. doi: 10.1002/cpt.1417. Epub 2019 Apr 8.

PMID:
30815856
3.

Synthesis of steroid bisglucuronide and sulfate glucuronide reference materials: Unearthing neglected treasures of steroid metabolism.

Pranata A, Fitzgerald CC, Khymenets O, Westley E, Anderson NJ, Ma P, Pozo OJ, McLeod MD.

Steroids. 2019 Mar;143:25-40. doi: 10.1016/j.steroids.2018.11.017. Epub 2018 Dec 1.

PMID:
30513322
4.

Improving liquid chromatography-tandem mass spectrometry determination of polycarboxylic acids in human urine by chemical derivatization. Comparison of o-benzyl hydroxylamine and 2-picolyl amine.

Gomez-Gomez A, Soldevila A, Pizarro N, Andreu-Fernandez V, Pozo OJ.

J Pharm Biomed Anal. 2019 Feb 5;164:382-394. doi: 10.1016/j.jpba.2018.10.055. Epub 2018 Nov 3.

PMID:
30466023
5.

Metabolomics predicts the pharmacological profile of new psychoactive substances.

Olesti E, De Toma I, Ramaekers JG, Brunt TM, Carbó ML, Fernández-Avilés C, Robledo P, Farré M, Dierssen M, Pozo ÓJ, de la Torre R.

J Psychopharmacol. 2019 Mar;33(3):347-354. doi: 10.1177/0269881118812103. Epub 2018 Nov 19.

PMID:
30451567
6.

Quantification of endogenous neurotransmitters and related compounds by liquid chromatography coupled to tandem mass spectrometry.

Olesti E, Rodríguez-Morató J, Gomez-Gomez A, Ramaekers JG, de la Torre R, Pozo OJ.

Talanta. 2019 Jan 15;192:93-102. doi: 10.1016/j.talanta.2018.09.034. Epub 2018 Sep 12.

PMID:
30348434
7.

Isotope dilution LC-ESI-MS/MS and low resolution selected reaction monitoring as a tool for the accurate quantification of urinary testosterone.

Ereño Artabe A, González-Gago A, Suarez Fernández A, Pitarch Motellón J, Roig-Navarro AF, Pozo OJ, Rodríguez-González P, García Alonso JI.

J Pharm Biomed Anal. 2019 Jan 30;163:113-121. doi: 10.1016/j.jpba.2018.09.038. Epub 2018 Sep 19.

PMID:
30292983
8.

GC/MS in Recent Years Has Defined the Normal and Clinically Disordered Steroidome: Will It Soon Be Surpassed by LC/Tandem MS in This Role?

Shackleton C, Pozo OJ, Marcos J.

J Endocr Soc. 2018 Jul 9;2(8):974-996. doi: 10.1210/js.2018-00135. eCollection 2018 Aug 1. Review.

9.

Targeting human urinary metabolome by LC-MS/MS: a review.

Rodríguez-Morató J, Pozo ÓJ, Marcos J.

Bioanalysis. 2018 Apr 1;10(7):489-516. doi: 10.4155/bio-2017-0285. Epub 2018 Mar 21. Review.

PMID:
29561651
10.

Maternal separation increases alcohol-drinking behaviour and reduces endocannabinoid levels in the mouse striatum and prefrontal cortex.

Portero-Tresserra M, Gracia-Rubio I, Cantacorps L, Pozo OJ, Gómez-Gómez A, Pastor A, López-Arnau R, de la Torre R, Valverde O.

Eur Neuropsychopharmacol. 2018 Apr;28(4):499-512. doi: 10.1016/j.euroneuro.2018.02.003. Epub 2018 Feb 23.

PMID:
29478745
11.

SULFATION PATHWAYS: Alternate steroid sulfation pathways targeted by LC-MS/MS analysis of disulfates: application to prenatal diagnosis of steroid synthesis disorders.

Pozo OJ, Marcos J, Khymenets O, Pranata A, Fitzgerald CC, McLeod MD, Shackleton C.

J Mol Endocrinol. 2018 Aug;61(2):M1-M12. doi: 10.1530/JME-17-0286. Epub 2018 Feb 19.

PMID:
29459491
12.

Evaluation of markers out of the steroid profile for the screening of testosterone misuse. Part II: Intramuscular administration.

Kotronoulas A, Gomez-Gómez À, Fabregat A, Segura J, Yang S, Xing Y, Moutian W, Marcos J, Joglar J, Ventura R, Pozo OJ.

Drug Test Anal. 2018 May;10(5):849-859. doi: 10.1002/dta.2342. Epub 2017 Dec 28.

PMID:
29166551
13.

Evaluation of markers out of the steroid profile for the screening of testosterone misuse. Part I: Transdermal administration.

Kotronoulas A, Gomez-Gómez À, Fabregat A, Segura J, Yang S, Xing Y, Moutian W, Marcos J, Joglar J, Ventura R, Pozo OJ.

Drug Test Anal. 2018 May;10(5):821-831. doi: 10.1002/dta.2338. Epub 2017 Dec 18.

PMID:
29148228
14.

Liquid chromatography tandem mass spectrometric determination of triterpenes in human fluids: Evaluation of markers of dietary intake of olive oil and metabolic disposition of oleanolic acid and maslinic acid in humans.

Pozo OJ, Pujadas M, Gleeson SB, Mesa-García MD, Pastor A, Kotronoulas A, Fitó M, Covas MI, Navarro JRF, Espejo JA, Sanchez-Rodriguez E, Marchal R, Calleja MA, de la Torre R.

Anal Chim Acta. 2017 Oct 16;990:84-95. doi: 10.1016/j.aca.2017.07.041. Epub 2017 Jul 21.

PMID:
29029746
15.

Pharmacokinetics of Mephedrone and Its Metabolites in Human by LC-MS/MS.

Olesti E, Farré M, Papaseit E, Krotonoulas A, Pujadas M, de la Torre R, Pozo ÓJ.

AAPS J. 2017 Nov;19(6):1767-1778. doi: 10.1208/s12248-017-0132-2. Epub 2017 Aug 21.

PMID:
28828691
16.

Normalizing Ovulation Rate by Preferential Reduction of Hepato-Visceral Fat in Adolescent Girls With Polycystic Ovary Syndrome.

Ibáñez L, Del Río L, Díaz M, Sebastiani G, Pozo ÓJ, López-Bermejo A, de Zegher F.

J Adolesc Health. 2017 Oct;61(4):446-453. doi: 10.1016/j.jadohealth.2017.04.010. Epub 2017 Jul 14.

PMID:
28712591
17.

Comprehensive analysis of the tryptophan metabolome in urine of patients with acute intermittent porphyria.

Gomez-Gomez A, Marcos J, Aguilera P, To-Figueras J, Pozo OJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Aug 15;1060:347-354. doi: 10.1016/j.jchromb.2017.06.030. Epub 2017 Jun 19.

PMID:
28666226
18.

Evaluation of uncertainty sources in the determination of testosterone in urine by calibration-based and isotope dilution quantification using ultra high performance liquid chromatography tandem mass spectrometry.

Pitarch-Motellón J, Roig-Navarro AF, Sancho JV, Ibáñez M, Fabregat-Cabello N, Pozo OJ, Ventura R, García Alonso JI, Rodríguez-González P, González Gago A, Ereño Artabe A, Van Eenoo P, Deventer K, Dehnes Y, Rzeppa S.

J Chromatogr A. 2017 Jul 28;1508:73-80. doi: 10.1016/j.chroma.2017.05.072. Epub 2017 Jun 3.

PMID:
28601363
19.

Quantifying endogenous androgens, estrogens, pregnenolone and progesterone metabolites in human urine by gas chromatography tandem mass spectrometry.

Robles J, Marcos J, Renau N, Garrostas L, Segura J, Ventura R, Barceló B, Barceló A, Pozo OJ.

Talanta. 2017 Jul 1;169:20-29. doi: 10.1016/j.talanta.2017.03.032. Epub 2017 Mar 11.

PMID:
28411812
20.

2-picolylamine derivatization for high sensitivity detection of abscisic acid in apicomplexan blood-infecting parasites.

Moles E, Marcos J, Imperial S, Pozo OJ, Fernàndez-Busquets X.

Talanta. 2017 Jun 1;168:130-135. doi: 10.1016/j.talanta.2017.03.030. Epub 2017 Mar 11.

21.

Constant Ion Loss Method for the Untargeted Detection of Bis-sulfate Metabolites.

McLeod MD, Waller CC, Esquivel A, Balcells G, Ventura R, Segura J, Pozo ÓJ.

Anal Chem. 2017 Feb 7;89(3):1602-1609. doi: 10.1021/acs.analchem.6b03671. Epub 2017 Jan 9.

PMID:
27982580
22.

Binge ethanol drinking during adolescence modifies cocaine responses in mice.

Esteve-Arenys A, Gracia-Rubio I, Cantacorps L, Pozo OJ, Marcos J, Rodríguez-Árias M, Miñarro J, Valverde O.

J Psychopharmacol. 2017 Jan;31(1):86-95. doi: 10.1177/0269881116681457. Epub 2016 Dec 9.

PMID:
27940500
23.

GC-MS Quantification Method for Mephedrone in Plasma and Urine: Application to Human Pharmacokinetics.

Olesti E, Pujadas M, Papaseit E, Pérez-Mañá C, Pozo ÓJ, Farré M, de la Torre R.

J Anal Toxicol. 2017 Mar 1;41(2):100-106. doi: 10.1093/jat/bkw120.

PMID:
27798075
24.

Sulfate metabolites as alternative markers for the detection of 4-chlorometandienone misuse in doping control.

Balcells G, Gómez C, Garrostas L, Pozo ÓJ, Ventura R.

Drug Test Anal. 2017 Jul;9(7):983-993. doi: 10.1002/dta.2101. Epub 2016 Oct 24.

PMID:
27686240
25.

Evaluation of two glucuronides resistant to enzymatic hydrolysis as markers of testosterone oral administration.

Kotronoulas A, Gomez-Gomez A, Segura J, Ventura R, Joglar J, Pozo OJ.

J Steroid Biochem Mol Biol. 2017 Jan;165(Pt B):212-218. doi: 10.1016/j.jsbmb.2016.06.006. Epub 2016 Jun 18.

PMID:
27328448
26.

LC-MS/MS detection of unaltered glucuronoconjugated metabolites of metandienone.

Esquivel A, Pozo OJ, Garrostas L, Balcells G, Gómez C, Kotronoulas A, Joglar J, Ventura R.

Drug Test Anal. 2017 Apr;9(4):534-544. doi: 10.1002/dta.1996. Epub 2016 May 30.

PMID:
27237125
27.

Detection and characterization of clostebol sulfate metabolites in Caucasian population.

Balcells G, Pozo OJ, Garrostas L, Esquivel A, Matabosch X, Kotronoulas A, Joglar J, Ventura R.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jun 1;1022:54-63. doi: 10.1016/j.jchromb.2016.03.028. Epub 2016 Mar 21.

PMID:
27085012
28.

Targeting tryptophan and tyrosine metabolism by liquid chromatography tandem mass spectrometry.

Marcos J, Renau N, Valverde O, Aznar-Laín G, Gracia-Rubio I, Gonzalez-Sepulveda M, Pérez-Jurado LA, Ventura R, Segura J, Pozo OJ.

J Chromatogr A. 2016 Feb 19;1434:91-101. doi: 10.1016/j.chroma.2016.01.023. Epub 2016 Jan 14.

PMID:
26818237
29.

Potential of atmospheric pressure chemical ionization source in gas chromatography tandem mass spectrometry for the screening of urinary exogenous androgenic anabolic steroids.

Raro M, Portolés T, Pitarch E, Sancho JV, Hernández F, Garrostas L, Marcos J, Ventura R, Segura J, Pozo OJ.

Anal Chim Acta. 2016 Feb 4;906:128-138. doi: 10.1016/j.aca.2015.11.041. Epub 2015 Dec 17.

PMID:
26772132
30.

In vitro metabolism study of a black market product containing SARM LGD-4033.

Geldof L, Pozo OJ, Lootens L, Morthier W, Van Eenoo P, Deventer K.

Drug Test Anal. 2017 Feb;9(2):168-178. doi: 10.1002/dta.1930. Epub 2016 Jan 15.

PMID:
26767942
31.

Current LC-MS methods and procedures applied to the identification of new steroid metabolites.

Marcos J, Pozo OJ.

J Steroid Biochem Mol Biol. 2016 Sep;162:41-56. doi: 10.1016/j.jsbmb.2015.12.012. Epub 2015 Dec 17. Review.

PMID:
26709140
32.

Chronic pain causes a persistent anxiety state leading to increased ethanol intake in CD1 mice.

González-Sepúlveda M, Pozo OJ, Marcos J, Valverde O.

J Psychopharmacol. 2016 Feb;30(2):188-203. doi: 10.1177/0269881115622238. Epub 2015 Dec 17.

PMID:
26681793
33.

Derivatization of steroids in biological samples for GC-MS and LC-MS analyses.

Marcos J, Pozo OJ.

Bioanalysis. 2015 Oct;7(19):2515-36. doi: 10.4155/bio.15.176. Epub 2015 Oct 19. Review.

PMID:
26478271
34.

Analytical strategy to investigate 3,4-methylenedioxypyrovalerone (MDPV) metabolites in consumers' urine by high-resolution mass spectrometry.

Ibáñez M, Pozo ÓJ, Sancho JV, Orengo T, Haro G, Hernández F.

Anal Bioanal Chem. 2016 Jan;408(1):151-64. doi: 10.1007/s00216-015-9088-1. Epub 2015 Oct 17.

PMID:
26476921
35.

Ultra high performance liquid chromatography tandem mass spectrometric detection of glucuronides resistant to enzymatic hydrolysis: Implications to doping control analysis.

Kotronoulas A, Marcos J, Segura J, Ventura R, Joglar J, Pozo OJ.

Anal Chim Acta. 2015 Oct 1;895:35-44. doi: 10.1016/j.aca.2015.08.043. Epub 2015 Sep 4.

PMID:
26454457
36.

Maternal separation induces neuroinflammation and long-lasting emotional alterations in mice.

Gracia-Rubio I, Moscoso-Castro M, Pozo OJ, Marcos J, Nadal R, Valverde O.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Feb 4;65:104-17. doi: 10.1016/j.pnpbp.2015.09.003. Epub 2015 Sep 14.

PMID:
26382758
37.

Mass spectrometric characterisation of a condensation product between porphobilinogen and indolyl-3-acryloylglycine in urine of patients with acute intermittent porphyria.

Marcos J, Ibañez M, Ventura R, Segura J, To-Figueras J, Pozo OJ.

J Mass Spectrom. 2015 Jul;50(7):929-37. doi: 10.1002/jms.3603.

PMID:
26349648
38.

Untargeted metabolomics in doping control: detection of new markers of testosterone misuse by ultrahigh performance liquid chromatography coupled to high-resolution mass spectrometry.

Raro M, Ibáñez M, Gil R, Fabregat A, Tudela E, Deventer K, Ventura R, Segura J, Marcos J, Kotronoulas A, Joglar J, Farré M, Yang S, Xing Y, Van Eenoo P, Pitarch E, Hernández F, Sancho JV, Pozo ÓJ.

Anal Chem. 2015 Aug 18;87(16):8373-80. doi: 10.1021/acs.analchem.5b02254. Epub 2015 Aug 5.

PMID:
26200763
39.

Factors affecting urinary excretion of testosterone metabolites conjugated with cysteine.

Fabregat A, Marcos J, Segura J, Ventura R, Pozo OJ.

Drug Test Anal. 2016 Jan;8(1):110-9. doi: 10.1002/dta.1801. Epub 2015 Apr 28.

PMID:
25917157
40.

Urinary cysteinyl progestogens: Occurrence and origin.

Marcos J, Pol M, Fabregat A, Ventura R, Renau N, Hanzu FA, Casals G, Marfà S, Barceló B, Barceló A, Robles J, Segura J, Pozo OJ.

J Steroid Biochem Mol Biol. 2015 Aug;152:53-61. doi: 10.1016/j.jsbmb.2015.04.015. Epub 2015 Apr 23.

PMID:
25913395
41.

Detection and characterization of prednisolone metabolites in human urine by LC-MS/MS.

Matabosch X, Pozo OJ, Pérez-Mañá C, Papaseit E, Segura J, Ventura R.

J Mass Spectrom. 2015 Mar;50(3):633-42. doi: 10.1002/jms.3571.

PMID:
25800201
42.

Screening for anabolic steroids in sports: analytical strategy based on the detection of phase I and phase II intact urinary metabolites by liquid chromatography tandem mass spectrometry.

Balcells G, Pozo OJ, Esquivel A, Kotronoulas A, Joglar J, Segura J, Ventura R.

J Chromatogr A. 2015 Apr 10;1389:65-75. doi: 10.1016/j.chroma.2015.02.022. Epub 2015 Feb 16.

PMID:
25746760
43.

Increased and mistimed sex hormone production in night shift workers.

Papantoniou K, Pozo OJ, Espinosa A, Marcos J, Castaño-Vinyals G, Basagaña X, Juanola Pagès E, Mirabent J, Martín J, Such Faro P, Gascó Aparici A, Middleton B, Skene DJ, Kogevinas M.

Cancer Epidemiol Biomarkers Prev. 2015 May;24(5):854-63. doi: 10.1158/1055-9965.EPI-14-1271. Epub 2015 Mar 3.

44.

Detection and characterization of triamcinolone acetonide metabolites in human urine by liquid chromatography/tandem mass spectrometry after intramuscular administration.

Matabosch X, Pozo OJ, Papaseit E, Farré M, Marcos J, Segura J, Ventura R.

Rapid Commun Mass Spectrom. 2014 Aug 30;28(16):1829-39. doi: 10.1002/rcm.6965.

PMID:
25559453
45.

Detection and characterization of betamethasone metabolites in human urine by LC-MS/MS.

Matabosch X, Pozo OJ, Monfort N, Pérez-Mañá C, Farré M, Segura J, Ventura R.

Drug Test Anal. 2015 Aug;7(8):663-72. doi: 10.1002/dta.1770. Epub 2014 Dec 26.

PMID:
25545348
46.

Formation of Δ(1) and Δ(6) testosterone metabolites by human hepatocytes.

Fabregat A, Marcos J, Ventura R, Casals G, Jimenez W, Reichenbach V, Segura J, Pozo OJ.

Steroids. 2015 Mar;95:66-72. doi: 10.1016/j.steroids.2014.12.006. Epub 2014 Dec 23.

PMID:
25541059
47.

Mass spectrometric evaluation of mephedrone in vivo human metabolism: identification of phase I and phase II metabolites, including a novel succinyl conjugate.

Pozo ÓJ, Ibáñez M, Sancho JV, Lahoz-Beneytez J, Farré M, Papaseit E, de la Torre R, Hernández F.

Drug Metab Dispos. 2015 Feb;43(2):248-57. doi: 10.1124/dmd.114.061416. Epub 2014 Dec 2.

PMID:
25468950
48.

Synthesis and characterization of 6β-hydroxyandrosterone and 6β-hydroxyetiocholanolone conjugated with glucuronic acid.

Kotronoulas A, Fabregat A, Alfonso I, Parella T, Segura J, Ventura R, Joglar J, Pozo OJ.

Drug Test Anal. 2015 Mar;7(3):247-52. doi: 10.1002/dta.1738. Epub 2014 Oct 31.

PMID:
25363899
49.

Evaluation of the reporting level to detect triamcinolone acetonide misuse in sports.

Matabosch X, Pozo OJ, Pérez-Mañá C, Papaseit E, Marcos J, Segura J, Ventura R.

J Steroid Biochem Mol Biol. 2015 Jan;145:94-102. doi: 10.1016/j.jsbmb.2014.09.018. Epub 2014 Sep 24.

PMID:
25260353
50.

Mass spectrometric behavior of anabolic androgenic steroids using gas chromatography coupled to atmospheric pressure chemical ionization source. Part I: ionization.

Raro M, Portolés T, Sancho JV, Pitarch E, Hernández F, Marcos J, Ventura R, Gómez C, Segura J, Pozo OJ.

J Mass Spectrom. 2014 Jun;49(6):509-21. doi: 10.1002/jms.3367.

PMID:
24913403

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