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Items: 15

1.

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.

Le Pichon CE, Meilandt WJ, Dominguez S, Solanoy H, Lin H, Ngu H, Gogineni A, Sengupta Ghosh A, Jiang Z, Lee SH, Maloney J, Gandham VD, Pozniak CD, Wang B, Lee S, Siu M, Patel S, Modrusan Z, Liu X, Rudhard Y, Baca M, Gustafson A, Kaminker J, Carano RAD, Huang EJ, Foreman O, Weimer R, Scearce-Levie K, Lewcock JW.

Sci Transl Med. 2017 Aug 16;9(403). pii: eaag0394. doi: 10.1126/scitranslmed.aag0394.

2.

Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.

Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee SH, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, Weimer RM, Kirkpatrick DS, Lewcock JW.

J Exp Med. 2013 Nov 18;210(12):2553-67. doi: 10.1084/jem.20122832. Epub 2013 Oct 28.

3.

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis.

Huntwork-Rodriguez S, Wang B, Watkins T, Ghosh AS, Pozniak CD, Bustos D, Newton K, Kirkpatrick DS, Lewcock JW.

J Cell Biol. 2013 Sep 2;202(5):747-63. doi: 10.1083/jcb.201303066. Epub 2013 Aug 26.

4.

Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization.

Stanger K, Steffek M, Zhou L, Pozniak CD, Quan C, Franke Y, Tom J, Tam C, Krylova I, Elliott JM, Lewcock JW, Zhang Y, Murray J, Hannoush RN.

Nat Chem Biol. 2012 Jul;8(7):655-60. doi: 10.1038/nchembio.967. Epub 2012 Jun 10. Erratum in: Nat Chem Biol. 2012 Jul;8(7). doi: 10.1038/nchembio.967. Krylova, Irina [added]. Nat Chem Biol. 2013 Jul;9(7):466.

PMID:
22683611
5.

A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C.

Mintzer R, Ramaswamy S, Shah K, Hannoush RN, Pozniak CD, Cohen F, Zhao X, Plise E, Lewcock JW, Heise CE.

PLoS One. 2012;7(1):e30376. doi: 10.1371/journal.pone.0030376. Epub 2012 Jan 12.

6.

DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity.

Ghosh AS, Wang B, Pozniak CD, Chen M, Watts RJ, Lewcock JW.

J Cell Biol. 2011 Sep 5;194(5):751-64. doi: 10.1083/jcb.201103153.

7.

Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expression.

Pozniak CD, Langseth AJ, Dijkgraaf GJ, Choe Y, Werb Z, Pleasure SJ.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21795-800. doi: 10.1073/pnas.1016485107. Epub 2010 Nov 22.

8.

Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon.

Langseth AJ, Munji RN, Choe Y, Huynh T, Pozniak CD, Pleasure SJ.

J Neurosci. 2010 Oct 6;30(40):13367-72. doi: 10.1523/JNEUROSCI.1934-10.2010.

9.

Genetic control of hippocampal neurogenesis.

Pozniak CD, Pleasure SJ.

Genome Biol. 2006;7(3):207. Epub 2006 Mar 30. Review.

10.

A tale of two signals: Wnt and Hedgehog in dentate neurogenesis.

Pozniak CD, Pleasure SJ.

Sci STKE. 2006 Jan 24;2006(319):pe5. Review.

PMID:
16434726
11.

p73 is required for survival and maintenance of CNS neurons.

Pozniak CD, Barnabé-Heider F, Rymar VV, Lee AF, Sadikot AF, Miller FD.

J Neurosci. 2002 Nov 15;22(22):9800-9.

12.

Neuronal life and death: an essential role for the p53 family.

Miller FD, Pozniak CD, Walsh GS.

Cell Death Differ. 2000 Oct;7(10):880-8. Review.

13.

An anti-apoptotic role for the p53 family member, p73, during developmental neuron death.

Pozniak CD, Radinovic S, Yang A, McKeon F, Kaplan DR, Miller FD.

Science. 2000 Jul 14;289(5477):304-6.

14.

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors.

Aloyz RS, Bamji SX, Pozniak CD, Toma JG, Atwal J, Kaplan DR, Miller FD.

J Cell Biol. 1998 Dec 14;143(6):1691-703.

15.

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death.

Bamji SX, Majdan M, Pozniak CD, Belliveau DJ, Aloyz R, Kohn J, Causing CG, Miller FD.

J Cell Biol. 1998 Feb 23;140(4):911-23.

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