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Items: 1 to 50 of 266

1.

Replacing Saturated Fat With Unsaturated Fat in Western Diet Reduces Foamy Monocytes and Atherosclerosis in Male Ldlr-/- Mice.

Lian Z, Perrard XD, Peng X, Raya JL, Hernandez AA, Johnson CG, Lagor WR, Pownall HJ, Hoogeveen RC, Simon SI, Sacks FM, Ballantyne CM, Wu H.

Arterioscler Thromb Vasc Biol. 2019 Oct 17:ATVBAHA119313078. doi: 10.1161/ATVBAHA.119.313078. [Epub ahead of print]

PMID:
31619061
2.

Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease.

Rodriguez A, Trigatti BL, Mineo C, Knaack D, Wilkins JT, Sahoo D, Asztalos BF, Mora S, Cuchel M, Pownall HJ, Rosales C, Bernatchez P, Ribeiro Martins da Silva A, Getz GS, Barber JL, Shearer GC, Zivkovic AM, Tietge UJF, Sacks FM, Connelly MA, Oda MN, Davidson WS, Sorci-Thomas MG, Vaisar T, Ruotolo G, Vickers KC, Martel C.

Arterioscler Thromb Vasc Biol. 2019 Oct 10:ATVBAHA119313340. doi: 10.1161/ATVBAHA.119.313340. [Epub ahead of print]

PMID:
31597448
3.

Revisiting Reverse Cholesterol Transport in the Context of High-Density Lipoprotein Free Cholesterol Bioavailability.

Rosales C, Gillard BK, Xu B, Gotto AM Jr, Pownall HJ.

Methodist Debakey Cardiovasc J. 2019 Jan-Mar;15(1):47-54. doi: 10.14797/mdcj-15-1-47. Review.

4.

Cholesterol: Can't Live With It, Can't Live Without It.

Pownall HJ, Gotto AM Jr.

Methodist Debakey Cardiovasc J. 2019 Jan-Mar;15(1):9-15. doi: 10.14797/mdcj-15-1-9. Review.

5.

Lipids and Cardiovascular Disease: Putting It All Together.

Pownall HJ, Gotto AM Jr.

Methodist Debakey Cardiovasc J. 2019 Jan-Mar;15(1):5-8. doi: 10.14797/mdcj-15-1-5. No abstract available.

6.

Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research.

Jarrett KE, Lee C, De Giorgi M, Hurley A, Gillard BK, Doerfler AM, Li A, Pownall HJ, Bao G, Lagor WR.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):1997-2006. doi: 10.1161/ATVBAHA.118.311221.

7.

Rethinking apolipoprotein A-II in lipid metabolism.

Pownall HJ.

Am J Clin Nutr. 2018 Jul 1;108(1):4-5. doi: 10.1093/ajcn/nqy136. No abstract available.

PMID:
29982311
8.

Rethinking reverse cholesterol transport and dysfunctional high-density lipoproteins.

Gillard BK, Rosales C, Xu B, Gotto AM Jr, Pownall HJ.

J Clin Lipidol. 2018 Jul - Aug;12(4):849-856. doi: 10.1016/j.jacl.2018.04.001. Epub 2018 Apr 12. Review.

9.

ABCA1-Derived Nascent High-Density Lipoprotein-Apolipoprotein AI and Lipids Metabolically Segregate.

Xu B, Gillard BK, Gotto AM Jr, Rosales C, Pownall HJ.

Arterioscler Thromb Vasc Biol. 2017 Dec;37(12):2260-2270. doi: 10.1161/ATVBAHA.117.310290. Epub 2017 Oct 26.

10.

Physical Function Following a Long-Term Lifestyle Intervention Among Middle Aged and Older Adults With Type 2 Diabetes: The Look AHEAD Study.

Houston DK, Neiberg RH, Miller ME, Hill JO, Jakicic JM, Johnson KC, Gregg EW, Hubbard VS, Pi-Sunyer X, Rejeski WJ, Wing RR, Bantle JP, Beale E, Berkowitz RI, Cassidy-Begay M, Clark JM, Coday M, Delahanty LM, Dutton G, Egan C, Foreyt JP, Greenway FL, Hazuda HP, Hergenroeder A, Horton ES, Jeffery RW, Kahn SE, Kure A, Knowler WC, Lewis CE, Martin CK, Michaels S, Montez MG, Nathan DM, Patricio J, Peters A, Pownall H, Regensteiner J, Steinburg H, Wadden TA, White K, Yanovski SZ, Zhang P, Kritchevsky SB.

J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1552-1559. doi: 10.1093/gerona/glx204.

11.

The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial.

Johnson KC, Bray GA, Cheskin LJ, Clark JM, Egan CM, Foreyt JP, Garcia KR, Glasser S, Greenway FL, Gregg EW, Hazuda HP, Hergenroeder A, Hill JO, Horton ES, Jakicic JM, Jeffery RW, Kahn SE, Knowler WC, Lewis CE, Miller M, Montez MG, Nathan DM, Patricio JL, Peters AL, Pi-Sunyer X, Pownall HJ, Reboussin D, Redmon JB, Steinberg H, Wadden TA, Wagenknecht LE, Wing RR, Womack CR, Yanovski SZ, Zhang P, Schwartz AV; Look AHEAD Study Group.

J Bone Miner Res. 2017 Nov;32(11):2278-2287. doi: 10.1002/jbmr.3214. Epub 2017 Jul 28.

12.

Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment.

Espeland MA, Luchsinger JA, Baker LD, Neiberg R, Kahn SE, Arnold SE, Wing RR, Blackburn GL, Bray G, Evans M, Hazuda HP, Jeffery RW, Wilson VM, Clark JM, Coday M, Demos-McDermott K, Foreyt JP, Greenway F, Hill JO, Horton ES, Jakicic JM, Johnson KC, Knowler WC, Lewis CE, Nathan DM, Peters A, Pi-Sunyer X, Pownall H, Wadden TA, Rapp SR; Look AHEAD Study Group.

Neurology. 2017 May 23;88(21):2026-2035. doi: 10.1212/WNL.0000000000003955. Epub 2017 Apr 26.

13.

Structural Stability of Streptococcal Serum Opacity Factor.

Yelamanchili D, Gillard BK, Gotto AM Jr, Pownall HJ, Rosales C.

Protein J. 2017 Jun;36(3):196-201. doi: 10.1007/s10930-017-9711-4.

14.

Scavenger receptor B1 (SR-B1) profoundly excludes high density lipoprotein (HDL) apolipoprotein AII as it nibbles HDL-cholesteryl ester.

Gillard BK, Bassett GR, Gotto AM Jr, Rosales C, Pownall HJ.

J Biol Chem. 2017 May 26;292(21):8864-8873. doi: 10.1074/jbc.M117.781963. Epub 2017 Apr 3.

15.

AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling.

Mao R, Meng S, Gu Q, Araujo-Gutierrez R, Kumar S, Yan Q, Almazan F, Youker KA, Fu Y, Pownall HJ, Cooke JP, Miller YI, Fang L.

Circ Res. 2017 May 26;120(11):1727-1739. doi: 10.1161/CIRCRESAHA.116.309754. Epub 2017 Mar 21.

16.

Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.

Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR.

Sci Rep. 2017 Mar 16;7:44624. doi: 10.1038/srep44624.

17.

Native and Reconstituted Plasma Lipoproteins in Nanomedicine: Physicochemical Determinants of Nanoparticle Structure, Stability, and Metabolism.

Pownall HJ, Rosales C, Gillard BK, Ferrari M.

Methodist Debakey Cardiovasc J. 2016 Sep;12(3):146-150. Review.

18.

Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial.

Look AHEAD Research Group, Gregg EW, Jakicic JM, Blackburn G, Bloomquist P, Bray GA, Clark JM, Coday M, Curtis JM, Egan C, Evans M, Foreyt J, Foster G, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jeffery RW, Johnson KC, Kitabchi AE, Knowler WC, Kriska A, Lang W, Lewis CE, Montez MG, Nathan DM, Neiberg RH, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Redmon B, Regensteiner J, Rejeski J, Ribisl PM, Safford M, Stewart K, Trence D, Wadden TA, Wing RR, Yanovski SZ.

Lancet Diabetes Endocrinol. 2016 Nov;4(11):913-921. doi: 10.1016/S2213-8587(16)30162-0. Epub 2016 Aug 30.

19.

Neo High-Density Lipoprotein Produced by the Streptococcal Serum Opacity Factor Activity against Human High-Density Lipoproteins Is Hepatically Removed via Dual Mechanisms.

Rodriguez PJ, Gillard BK, Barosh R, Gotto AM Jr, Rosales C, Pownall HJ.

Biochemistry. 2016 Oct 18;55(41):5845-5853. doi: 10.1021/acs.biochem.6b00946. Epub 2016 Oct 7.

PMID:
27662183
20.

Acylation of lysine residues in human plasma high density lipoprotein increases stability and plasma clearance in vivo.

Yang Y, Rosales C, Gillard BK, Gotto AM Jr, Pownall HJ.

Biochim Biophys Acta. 2016 Nov;1861(11):1787-1795. doi: 10.1016/j.bbalip.2016.08.017. Epub 2016 Sep 2.

21.

Changes in regional body composition over 8 years in a randomized lifestyle trial: The look AHEAD study.

Pownall HJ, Schwartz AV, Bray GA, Berkowitz RI, Lewis CE, Boyko EJ, Jakicic JM, Chen H, Heshka S, Gregg EW, Johnson KC; Look AHEAD Research Group.

Obesity (Silver Spring). 2016 Sep;24(9):1899-905. doi: 10.1002/oby.21577. Epub 2016 Jul 28.

22.

Effects of visceral adipose tissue reduction on CVD risk factors independent of weight loss: The Look AHEAD study.

Sanguankeo A, Lazo M, Upala S, Brancati FL, Bonekamp S, Pownall HJ, Balasubramanyam A, Clark JM; Fatty Liver Subgroup of the Look AHEAD Research Group.

Endocr Res. 2017 May;42(2):86-95. doi: 10.1080/07435800.2016.1194856. Epub 2016 Jun 28.

23.

Association of Weight Loss Maintenance and Weight Regain on 4-Year Changes in CVD Risk Factors: the Action for Health in Diabetes (Look AHEAD) Clinical Trial.

Wing RR, Espeland MA, Clark JM, Hazuda HP, Knowler WC, Pownall HJ, Unick J, Wadden T, Wagenknecht L; Action for Health in Diabetes (Look AHEAD) Study Group.

Diabetes Care. 2016 Aug;39(8):1345-55. doi: 10.2337/dc16-0509. Epub 2016 Jun 6. Erratum in: Diabetes Care. 2016 Dec;39(12 ):2318.

24.

Speciated High-Density Lipoprotein Biogenesis and Functionality.

Rosales C, Davidson WS, Gillard BK, Gotto AM Jr, Pownall HJ.

Curr Atheroscler Rep. 2016 May;18(5):25. doi: 10.1007/s11883-016-0572-7. Review.

PMID:
27005803
25.

E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis.

Ma S, Tian XY, Zhang Y, Mu C, Shen H, Bismuth J, Pownall HJ, Huang Y, Wong WT.

Sci Rep. 2016 Mar 9;6:22910. doi: 10.1038/srep22910.

26.

Direct Measurement of the Structure of Reconstituted High-Density Lipoproteins by Cryo-EM.

Murray SC, Gillard BK, Ludtke SJ, Pownall HJ.

Biophys J. 2016 Feb 23;110(4):810-6. doi: 10.1016/j.bpj.2015.10.028. Epub 2015 Dec 30.

27.

Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo.

Gillard BK, Rodriguez PJ, Fields DW, Raya JL, Lagor WR, Rosales C, Courtney HS, Gotto AM Jr, Pownall HJ.

Biochim Biophys Acta. 2016 Mar;1861(3):196-204. doi: 10.1016/j.bbalip.2015.12.006. Epub 2015 Dec 18.

28.

New Insights into the High-Density Lipoprotein Dilemma.

Pownall HJ, Gotto AM Jr.

Trends Endocrinol Metab. 2016 Jan;27(1):44-53. doi: 10.1016/j.tem.2015.11.004. Epub 2015 Dec 7. Review.

29.

High-Density Lipoprotein Processing and Premature Cardiovascular Disease.

Rosales C, Gillard BK, Gotto AM Jr, Pownall HJ.

Methodist Debakey Cardiovasc J. 2015 Jul-Sep;11(3):181-5. doi: 10.14797/mdcj-11-3-181. Review.

30.

Estrogen: an emerging regulator of insulin action and mitochondrial function.

Gupte AA, Pownall HJ, Hamilton DJ.

J Diabetes Res. 2015;2015:916585. doi: 10.1155/2015/916585. Epub 2015 Mar 26. Review.

31.

Alcohol: a nutrient with multiple salutary effects.

Pownall HJ, Rosales C, Gillard BK, Gotto AM Jr.

Nutrients. 2015 Mar 18;7(3):1992-2000. doi: 10.3390/nu7031992. Review.

32.

Apolipoprotein AI deficiency inhibits serum opacity factor activity against plasma high density lipoprotein via a stabilization mechanism.

Rosales C, Patel N, Gillard BK, Yelamanchili D, Yang Y, Courtney HS, Santos RD, Gotto AM Jr, Pownall HJ.

Biochemistry. 2015 Apr 14;54(14):2295-302. doi: 10.1021/bi501486z. Epub 2015 Apr 2.

33.

Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: the look AHEAD study.

Pownall HJ, Bray GA, Wagenknecht LE, Walkup MP, Heshka S, Hubbard VS, Hill J, Kahn SE, Nathan DM, Schwartz AV, Johnson KC; Look AHEAD Research Group.

Obesity (Silver Spring). 2015 Mar;23(3):565-72. doi: 10.1002/oby.21005.

34.

Impact of an intensive lifestyle intervention on use and cost of medical services among overweight and obese adults with type 2 diabetes: the action for health in diabetes.

Espeland MA, Glick HA, Bertoni A, Brancati FL, Bray GA, Clark JM, Curtis JM, Egan C, Evans M, Foreyt JP, Ghazarian S, Gregg EW, Hazuda HP, Hill JO, Hire D, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Killean T, Kitabchi AE, Knowler WC, Kriska A, Lewis CE, Miller M, Montez MG, Murillo A, Nathan DM, Nyenwe E, Patricio J, Peters AL, Pi-Sunyer X, Pownall H, Redmon JB, Rushing J, Ryan DH, Safford M, Tsai AG, Wadden TA, Wing RR, Yanovski SZ, Zhang P; Look AHEAD Research Group.

Diabetes Care. 2014 Sep;37(9):2548-56. doi: 10.2337/dc14-0093.

35.

Setting the course for apoAII: a port in sight?

Pownall HJ, Gillard BK, Gotto AM Jr.

Clin Lipidol. 2013 Oct;8(5):551-560.

36.

Impact of intensive lifestyle intervention on depression and health-related quality of life in type 2 diabetes: the Look AHEAD Trial.

Rubin RR, Wadden TA, Bahnson JL, Blackburn GL, Brancati FL, Bray GA, Coday M, Crow SJ, Curtis JM, Dutton G, Egan C, Evans M, Ewing L, Faulconbridge L, Foreyt J, Gaussoin SA, Gregg EW, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Knowler WC, Lang W, Lewis CE, Montez MG, Murillo A, Nathan DM, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Rejeski WJ, Rosenthal RH, Ruelas V, Toledo K, Van Dorsten B, Vitolins M, Williamson D, Wing RR, Yanovski SZ, Zhang P; Look AHEAD Research Group.

Diabetes Care. 2014 Jun;37(6):1544-53. doi: 10.2337/dc13-1928.

37.

Commentary on fatty acid wars: the diffusionists versus the translocatists.

Pownall H, Moore K.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):e8-9. doi: 10.1161/ATVBAHA.114.303380. Epub 2014 Mar 20. No abstract available.

38.

Modest diet-induced weight loss reduces macrophage cholesterol efflux to plasma of patients with metabolic syndrome.

Vasudevan M, Tchoua U, Gillard BK, Jones PH, Ballantyne CM, Pownall HJ.

J Clin Lipidol. 2013 Nov-Dec;7(6):661-70. doi: 10.1016/j.jacl.2013.05.004. Epub 2013 May 25.

39.

Do genetic modifiers of high-density lipoprotein cholesterol and triglyceride levels also modify their response to a lifestyle intervention in the setting of obesity and type-2 diabetes mellitus?: The Action for Health in Diabetes (Look AHEAD) study.

Huggins GS, Papandonatos GD, Erar B, Belalcazar LM, Brautbar A, Ballantyne C, Kitabchi AE, Wagenknecht LE, Knowler WC, Pownall HJ, Wing RR, Peter I, McCaffery JM; Genetics Subgroup of the Action for Health in Diabetes (Look AHEAD) Study.

Circ Cardiovasc Genet. 2013 Aug;6(4):391-9. doi: 10.1161/CIRCGENETICS.113.000042. Epub 2013 Jul 16.

40.

Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.

Look AHEAD Research Group, Wing RR, Bolin P, Brancati FL, Bray GA, Clark JM, Coday M, Crow RS, Curtis JM, Egan CM, Espeland MA, Evans M, Foreyt JP, Ghazarian S, Gregg EW, Harrison B, Hazuda HP, Hill JO, Horton ES, Hubbard VS, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Kitabchi AE, Knowler WC, Lewis CE, Maschak-Carey BJ, Montez MG, Murillo A, Nathan DM, Patricio J, Peters A, Pi-Sunyer X, Pownall H, Reboussin D, Regensteiner JG, Rickman AD, Ryan DH, Safford M, Wadden TA, Wagenknecht LE, West DS, Williamson DF, Yanovski SZ.

N Engl J Med. 2013 Jul 11;369(2):145-54. doi: 10.1056/NEJMoa1212914. Epub 2013 Jun 24. Erratum in: N Engl J Med. 2014 May 8;370(19):1866.

41.

Free cholesterol determines reassembled high-density lipoprotein phospholipid phase structure and stability.

Auton M, Bassett GR, Gillard BK, Pownall HJ.

Biochemistry. 2013 Jun 25;52(25):4324-30. doi: 10.1021/bi4006732. Epub 2013 Jun 14.

42.

Impaired lipoprotein processing in HIV patients on antiretroviral therapy: aberrant high-density lipoprotein lipids, stability, and function.

Gillard BK, Raya JL, Ruiz-Esponda R, Iyer D, Coraza I, Balasubramanyam A, Pownall HJ.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1714-21. doi: 10.1161/ATVBAHA.113.301538. Epub 2013 May 2.

43.

Relationship of ethnicity and CD4 Count with glucose metabolism among HIV patients on Highly-Active Antiretroviral Therapy (HAART).

Misra R, Chandra P, Riechman SE, Long DM, Shinde S, Pownall HJ, Coraza I, Lewis DE, Sekhar RV, Balasubramanyam A.

BMC Endocr Disord. 2013 Apr 22;13:13. doi: 10.1186/1472-6823-13-13.

44.

Altered relationship of plasma triglycerides to HDL cholesterol in patients with HIV/HAART-associated dyslipidemia: further evidence for a unique form of metabolic syndrome in HIV patients.

Vu CN, Ruiz-Esponda R, Yang E, Chang E, Gillard B, Pownall HJ, Hoogeveen RC, Coraza I, Balasubramanyam A.

Metabolism. 2013 Jul;62(7):1014-20. doi: 10.1016/j.metabol.2013.01.020. Epub 2013 Mar 19.

45.

Intensive lifestyle modification reduces Lp-PLA2 in dyslipidemic HIV/HAART patients.

Wooten JS, Nambi P, Gillard BK, Pownall HJ, Coraza I, Scott LW, Nambi V, Ballantyne CM, Balasubramanyam A.

Med Sci Sports Exerc. 2013 Jun;45(6):1043-50. doi: 10.1249/MSS.0b013e3182843961.

46.

Association of an intensive lifestyle intervention with remission of type 2 diabetes.

Gregg EW, Chen H, Wagenknecht LE, Clark JM, Delahanty LM, Bantle J, Pownall HJ, Johnson KC, Safford MM, Kitabchi AE, Pi-Sunyer FX, Wing RR, Bertoni AG; Look AHEAD Research Group.

JAMA. 2012 Dec 19;308(23):2489-96. doi: 10.1001/jama.2012.67929.

47.

Cholesterol determines and limits rHDL formation from human plasma apolipoprotein A-II and phospholipid membranes.

Bassett GR, Gillard BK, Pownall HJ.

Biochemistry. 2012 Oct 30;51(43):8627-35. doi: 10.1021/bi3011994. Epub 2012 Oct 16.

48.

ApoE and the role of very low density lipoproteins in adipose tissue inflammation.

Wang J, Perrard XD, Perrard JL, Mukherjee A, Rosales C, Chen Y, Smith CW, Pownall HJ, Ballantyne CM, Wu H.

Atherosclerosis. 2012 Aug;223(2):342-9. doi: 10.1016/j.atherosclerosis.2012.06.003. Epub 2012 Jun 19.

49.

Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein.

Zhang L, Yan F, Zhang S, Lei D, Charles MA, Cavigiolio G, Oda M, Krauss RM, Weisgraber KH, Rye KA, Pownall HJ, Qiu X, Ren G.

Nat Chem Biol. 2012 Feb 19;8(4):342-9. doi: 10.1038/nchembio.796.

50.

ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial.

Smart-Halajko MC, Kelley-Hedgepeth A, Montefusco MC, Cooper JA, Kopin A, McCaffrey JM, Balasubramanyam A, Pownall HJ, Nathan DM, Peter I, Talmud PJ, Huggins GS; Look AHEAD Study.

BMC Med Genet. 2011 Jun 29;12:89. doi: 10.1186/1471-2350-12-89.

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