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Items: 1 to 50 of 66

1.

Estimates of the global population of children who are HIV-exposed and uninfected, 2000-18: a modelling study.

Slogrove AL, Powis KM, Johnson LF, Stover J, Mahy M.

Lancet Glob Health. 2019 Nov 29. pii: S2214-109X(19)30448-6. doi: 10.1016/S2214-109X(19)30448-6. [Epub ahead of print]

2.

Early antiretroviral therapy in neonates with HIV-1 infection restricts viral reservoir size and induces a distinct innate immune profile.

Garcia-Broncano P, Maddali S, Einkauf KB, Jiang C, Gao C, Chevalier J, Chowdhury FZ, Maswabi K, Ajibola G, Moyo S, Mohammed T, Ncube T, Makhema J, Jean-Philippe P, Yu XG, Powis KM, Lockman S, Kuritzkes DR, Shapiro R, Lichterfeld M.

Sci Transl Med. 2019 Nov 27;11(520). pii: eaax7350. doi: 10.1126/scitranslmed.aax7350.

PMID:
31776292
3.

Comparison of knowledge of HIV status and treatment coverage between non-citizens and citizens: Botswana Combination Prevention Project (BCPP).

Marukutira T, Block L, Alwano MG, Behel S, Jarvis JN, Chakalisa U, Powis K, Novitsky V, Bapati W, Wang H, Ussery F, Lebelonyane R, Mills LA, Moore J, Bachanas P.

PLoS One. 2019 Aug 29;14(8):e0221629. doi: 10.1371/journal.pone.0221629. eCollection 2019.

4.

Unmasking the vulnerabilities of uninfected children exposed to HIV.

Ramokolo V, Goga AE, Slogrove AL, Powis KM.

BMJ. 2019 Aug 5;366:l4479. doi: 10.1136/bmj.l4479. No abstract available.

5.

Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana.

Makhema J, Wirth KE, Pretorius Holme M, Gaolathe T, Mmalane M, Kadima E, Chakalisa U, Bennett K, Leidner J, Manyake K, Mbikiwa AM, Simon SV, Letlhogile R, Mukokomani K, van Widenfelt E, Moyo S, Lebelonyane R, Alwano MG, Powis KM, Dryden-Peterson SL, Kgathi C, Novitsky V, Moore J, Bachanas P, Abrams W, Block L, El-Halabi S, Marukutira T, Mills LA, Sexton C, Raizes E, Gaseitsiwe S, Bussmann H, Okui L, John O, Shapiro RL, Pals S, Michael H, Roland M, DeGruttola V, Lei Q, Wang R, Tchetgen Tchetgen E, Essex M, Lockman S.

N Engl J Med. 2019 Jul 18;381(3):230-242. doi: 10.1056/NEJMoa1812281.

PMID:
31314967
6.

Self-reported risky sexual practices among adolescents and young adults in Botswana.

Chakalisa U, Wirth K, Bennett K, Kadima E, Manyake K, Gaolathe T, Bachanas P, Marukutira T, Lebelonyane R, Dryden-Peterson S, Butler L, Mmalane M, Makhema J, Roland ME, Pretorius-Holme M, Essex M, Lockman S, Powis KM.

South Afr J HIV Med. 2019 Jun 26;20(1):899. doi: 10.4102/sajhivmed.v20i1.899. eCollection 2019.

7.

Investment Long Overdue in Primary Studies of HIV-exposed Uninfected Infant Infectious Morbidity.

Slogrove AL, Powis KM.

Pediatr Infect Dis J. 2019 Jul;38(7):e164-e165. doi: 10.1097/INF.0000000000002249. No abstract available.

PMID:
31192984
8.

In Utero Efavirenz Exposure and Neurodevelopmental Outcomes in HIV-exposed Uninfected Children in Botswana.

Cassidy AR, Williams PL, Leidner J, Mayondi G, Ajibola G, Makhema J, Holding PA, Powis KM, Batlang O, Petlo C, Shapiro R, Kammerer B, Lockman S.

Pediatr Infect Dis J. 2019 Aug;38(8):828-834. doi: 10.1097/INF.0000000000002332.

PMID:
30985518
9.

Methodological Considerations in Evaluating Pregnancy Outcomes in Women Living With HIV.

Slogrove AL, Powis KM, Zash R.

J Acquir Immune Defic Syndr. 2019 Jun 1;81(2):e63-e64. doi: 10.1097/QAI.0000000000002014. No abstract available.

PMID:
30839382
10.

Optimising HIV antiretrovirals for mothers and infants.

Powis KM, Siberry GK.

Lancet HIV. 2019 May;6(5):e272-e273. doi: 10.1016/S2352-3018(19)30045-1. Epub 2019 Feb 24. No abstract available.

PMID:
30814029
11.

Fetal origins of postnatal growth faltering in HIV-exposed uninfected children.

Slogrove AL, Powis KM.

Lancet Child Adolesc Health. 2019 Apr;3(4):201-203. doi: 10.1016/S2352-4642(19)30023-9. Epub 2019 Feb 15. No abstract available.

PMID:
30773460
12.

Human Immunodeficiency Virus-exposed Uninfected Infants: Surviving and Thriving or Overlooked by Success?

Slogrove AL, Powis KM, Cotton MF.

Clin Infect Dis. 2019 May 30;68(12):2156-2158. doi: 10.1093/cid/ciy1056. No abstract available.

PMID:
30535339
13.

Maternal Perinatal HIV Infection Is Associated With Increased Infectious Morbidity in HIV-exposed Uninfected Infants.

Powis KM, Slogrove AL, Okorafor I, Millen L, Posada R, Childs J, Abrams EJ, Sperling RS, Jao J.

Pediatr Infect Dis J. 2019 May;38(5):500-502. doi: 10.1097/INF.0000000000002253.

PMID:
30461574
14.

Considerations in evaluating infectious morbidity and mortality in HIV-exposed uninfected infants.

Slogrove AL, Powis KM, Bettinger JA, Cotton MF.

AIDS. 2018 Nov 28;32(18):2855-2856. doi: 10.1097/QAD.0000000000002049. No abstract available.

15.

Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015.

Moyo S, Gaseitsiwe S, Mohammed T, Pretorius Holme M, Wang R, Kotokwe KP, Boleo C, Mupfumi L, Yankinda EK, Chakalisa U, van Widenfelt E, Gaolathe T, Mmalane MO, Dryden-Peterson S, Mine M, Lebelonyane R, Bennett K, Leidner J, Wirth KE, Tchetgen Tchetgen E, Powis K, Moore J, Clarke WA, Lockman S, Makhema JM, Essex M, Novitsky V.

PLoS One. 2018 Oct 24;13(10):e0204840. doi: 10.1371/journal.pone.0204840. eCollection 2018.

16.

Population-level Mortality Associated with HIV Exposure in HIV-uninfected Infants in Botswana and South Africa: A Model-based Evaluation.

Slogrove AL, Johnson LF, Powis KM.

J Trop Pediatr. 2019 Aug 1;65(4):373-379. doi: 10.1093/tropej/fmy064.

17.

Surviving and Thriving-Shifting the Public Health Response to HIV-Exposed Uninfected Children: Report of the 3rd HIV-Exposed Uninfected Child Workshop.

Slogrove AL, Becquet R, Chadwick EG, Côté HCF, Essajee S, Hazra R, Leroy V, Mahy M, Murenga M, Wambui Mwangi J, Oyiengo L, Rollins N, Penazzato M, Seage GR 3rd, Serghides L, Vicari M, Powis KM.

Front Pediatr. 2018 May 30;6:157. doi: 10.3389/fped.2018.00157. eCollection 2018.

18.

Cryptic Plutella species show deep divergence despite the capacity to hybridize.

Perry KD, Baker GJ, Powis KJ, Kent JK, Ward CM, Baxter SW.

BMC Evol Biol. 2018 May 29;18(1):77. doi: 10.1186/s12862-018-1183-4.

19.

Lack of Virological Suppression Among Young HIV-Positive Adults in Botswana.

Novitsky V, Gaolathe T, Mmalane M, Moyo S, Chakalisa U, Yankinda EK, Marukutira T, Holme MP, Sekoto T, Gaseitsiwe S, Musonda R, van Widenfelt E, Powis KM, Khan N, Dryden-Peterson S, Bennett K, Wirth KE, Tchetgen ET, Bachanas P, Mills LA, Lebelonyane R, El-Halabi S, Makhema J, Lockman S, Essex M.

J Acquir Immune Defic Syndr. 2018 Aug 15;78(5):557-565. doi: 10.1097/QAI.0000000000001715.

20.

Undisclosed antiretroviral drug use in Botswana: implication for national estimates.

Moyo S, Gaseitsiwe S, Powis KM, Pretorius Holme M, Mohammed T, Zahralban-Steele M, Yankinde EK, Maphorisa C, Abrams W, Lebelonyane R, Manyake K, Sekoto T, Mmalane M, Gaolathe T, Wirth KE, Makhema J, Lockman S, Clarke W, Essex M, Novitsky V.

AIDS. 2018 Jul 17;32(11):1543-1546. doi: 10.1097/QAD.0000000000001862.

21.

Hearing Impairment Among Children Referred to a Public Audiology Clinic in Gaborone, Botswana.

Banda FM, Powis KM, Mokoka AB, Mmapetla M, Westmoreland KD, David T, Steenhoff AP.

Glob Pediatr Health. 2018 Apr 20;5:2333794X18770079. doi: 10.1177/2333794X18770079. eCollection 2018.

22.

Similar HIV protection from four weeks of zidovudine versus nevirapine prophylaxis among formula-fed infants in Botswana.

Powis KM, Lockman S, Ajibola G, Hughes MD, Bennett K, Leidner J, Batlang O, Botebele K, Moyo S, van Widenfelt E, Makhema J, Petlo C, Jibril HB, McIntosh K, Essex M, Shapiro RL.

South Afr J HIV Med. 2018 Mar 28;19(1):751. doi: 10.4102/sajhivmed.v19i1.751. eCollection 2018.

23.

High HIV-1 RNA Among Newly Diagnosed People in Botswana.

Novitsky V, Prague M, Moyo S, Gaolathe T, Mmalane M, Yankinda EK, Chakalisa U, Lebelonyane R, Khan N, Powis KM, Widenfelt E, Gaseitsiwe S, Dryden-Peterson SL, Holme MP, De Gruttola V, Bachanas P, Makhema J, Lockman S, Essex M.

AIDS Res Hum Retroviruses. 2018 Mar;34(3):300-306. doi: 10.1089/AID.2017.0214. Epub 2018 Jan 17.

24.

Cotrimoxazole prophylaxis was associated with enteric commensal bacterial resistance among HIV-exposed infants in a randomized controlled trial, Botswana.

Powis KM, Souda S, Lockman S, Ajibola G, Bennett K, Leidner J, Hughes MD, Moyo S, van Widenfelt E, Jibril HB, Makhema J, Essex M, Shapiro RL.

J Int AIDS Soc. 2017 Nov;20(3). doi: 10.1002/jia2.25021.

25.

Lower mitochondrial DNA and altered mitochondrial fuel metabolism in HIV-exposed uninfected infants in Cameroon.

Jao J, Powis KM, Kirmse B, Yu C, Epie F, Nshom E, Abrams EJ, Sperling RS, Leroith D, Geffner ME, Kurland IJ, Côté HCF.

AIDS. 2017 Nov 28;31(18):2475-2481. doi: 10.1097/QAD.0000000000001647.

26.

Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial.

Lockman S, Hughes M, Powis K, Ajibola G, Bennett K, Moyo S, van Widenfelt E, Leidner J, McIntosh K, Mazhani L, Makhema J, Essex M, Shapiro R.

Lancet Glob Health. 2017 May;5(5):e491-e500. doi: 10.1016/S2214-109X(17)30143-2.

27.

Detecting congenital malformations - Lessons learned from the Mpepu study, Botswana.

Ajibola G, Zash R, Shapiro RL, Batlang O, Botebele K, Bennett K, Chilisa F, Widenfelt EV, Makhema J, Lockman S, Holmes LB, Powis KM.

PLoS One. 2017 Mar 24;12(3):e0173800. doi: 10.1371/journal.pone.0173800. eCollection 2017.

28.

High Proportion of Deaths Attributable to HIV Among Postpartum Women in Botswana Despite Widespread Uptake of Antiretroviral Therapy.

Zash RM, Souda S, Leidner J, Binda K, Hick C, Powis K, Makhema J, Mmalane M, Essex M, Lockman S, Shapiro RL.

AIDS Patient Care STDS. 2017 Jan;31(1):14-19. doi: 10.1089/apc.2016.0154.

29.

Protecting the health of our AIDS-free generation: beyond prevention of mother-to-child HIV transmission.

Powis KM, Slogrove AL, Mofenson L.

AIDS. 2017 Jan 14;31(2):315-316. doi: 10.1097/QAD.0000000000001315. No abstract available.

30.

Point-of-Care Cepheid Xpert HIV-1 Viral Load Test in Rural African Communities Is Feasible and Reliable.

Moyo S, Mohammed T, Wirth KE, Prague M, Bennett K, Holme MP, Mupfumi L, Sebogodi P, Moraka NO, Boleo C, Maphorisa CN, Seraise B, Gaseitsiwe S, Musonda RM, van Widenfelt E, Powis KM, Gaolathe T, Tchetgen Tchetgen EJ, Makhema JM, Essex M, Lockman S, Novitsky V.

J Clin Microbiol. 2016 Dec;54(12):3050-3055. Epub 2016 Oct 12.

31.

Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signaling.

Powis K, De Virgilio C.

Cell Discov. 2016 Mar 8;2:15049. doi: 10.1038/celldisc.2015.49. eCollection 2016. Review.

32.

HIV-exposed children account for more than half of 24-month mortality in Botswana.

Zash R, Souda S, Leidner J, Ribaudo H, Binda K, Moyo S, Powis KM, Petlo C, Mmalane M, Makhema J, Essex M, Lockman S, Shapiro R.

BMC Pediatr. 2016 Jul 21;16:103. doi: 10.1186/s12887-016-0635-5.

33.

Predictors of early breastfeeding cessation among HIV-infected women in Botswana.

Ogwu A, Moyo S, Powis K, Asmelash A, Lockman S, Moffat C, Leidner J, Makhema J, Essex M, Shapiro R.

Trop Med Int Health. 2016 Aug;21(8):1013-1018. doi: 10.1111/tmi.12729. Epub 2016 Jun 16.

34.

Hidden in plain sight: HIV, antiretrovirals, and stillbirths.

Shapiro R, Dryden-Peterson S, Powis K, Zash R, Lockman S.

Lancet. 2016 May 14;387(10032):1994-5. doi: 10.1016/S0140-6736(16)30459-7. No abstract available.

PMID:
27203765
35.

HIV-related mortality at a district hospital in Botswana.

Perry ME, Kalenga K, Watkins LF, Mukaya JE, Powis KM, Bennett K, Mmalane M, Makhema J, Shapiro RL.

Int J STD AIDS. 2017 Mar;28(3):277-283. doi: 10.1177/0956462416646492. Epub 2016 Jul 10.

PMID:
27164967
36.

Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey.

Gaolathe T, Wirth KE, Holme MP, Makhema J, Moyo S, Chakalisa U, Yankinda EK, Lei Q, Mmalane M, Novitsky V, Okui L, van Widenfelt E, Powis KM, Khan N, Bennett K, Bussmann H, Dryden-Peterson S, Lebelonyane R, El-Halabi S, Mills LA, Marukutira T, Wang R, Tchetgen EJ, DeGruttola V, Essex M, Lockman S; Botswana Combination Prevention Project study team.

Lancet HIV. 2016 May;3(5):e221-30. doi: 10.1016/S2352-3018(16)00037-0. Epub 2016 Mar 24.

37.

Linear Growth Faltering Among HIV-Exposed Uninfected Children.

Sudfeld CR, Lei Q, Chinyanga Y, Tumbare E, Khan N, Dapaah-Siakwan F, Sebaka A, Sibiya J, van Widenfelt E, Shapiro RL, Makhema J, Fawzi WW, Powis KM.

J Acquir Immune Defic Syndr. 2016 Oct 1;73(2):182-9. doi: 10.1097/QAI.0000000000001034.

38.

Behavioral Avoidance - Will Physiological Insecticide Resistance Level of Insect Strains Affect Their Oviposition and Movement Responses?

Nansen C, Baissac O, Nansen M, Powis K, Baker G.

PLoS One. 2016 Mar 4;11(3):e0149994. doi: 10.1371/journal.pone.0149994. eCollection 2016.

39.

Determining the drift potential of Venturi nozzles compared with standard nozzles across three insecticide spray solutions in a wind tunnel.

Ferguson JC, Chechetto RG, O'Donnell CC, Dorr GJ, Moore JH, Baker GJ, Powis KJ, Hewitt AJ.

Pest Manag Sci. 2016 Aug;72(8):1460-6. doi: 10.1002/ps.4214. Epub 2016 Feb 2.

PMID:
26732308
40.

In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana.

Powis KM, Smeaton L, Hughes MD, Tumbare EA, Souda S, Jao J, Wirth KE, Makhema J, Lockman S, Fawzi W, Essex M, Shapiro RL.

AIDS. 2016 Jan;30(2):211-20. doi: 10.1097/QAD.0000000000000895.

41.

Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling.

Powis K, Zhang T, Panchaud N, Wang R, De Virgilio C, Ding J.

Cell Res. 2015 Sep;25(9):1043-59. doi: 10.1038/cr.2015.86. Epub 2015 Jul 24.

42.

Lower Preprandial Insulin and Altered Fuel Use in HIV/Antiretroviral-Exposed Infants in Cameroon.

Jao J, Kirmse B, Yu C, Qiu Y, Powis K, Nshom E, Epie F, Tih PM, Sperling RS, Abrams EJ, Geffner ME, LeRoith D, Kurland IJ.

J Clin Endocrinol Metab. 2015 Sep;100(9):3260-9. doi: 10.1210/JC.2015-2198. Epub 2015 Jul 2.

43.

Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana.

Powis K, Lockman S, Smeaton L, Hughes MD, Fawzi W, Ogwu A, Moyo S, van Widenfelt E, von Oettingen J, Makhema J, Essex M, Shapiro RL.

Pediatr Infect Dis J. 2014 Nov;33(11):1141-7. doi: 10.1097/INF.0000000000000428.

44.

Protease inhibitors and adverse birth outcomes: is progesterone the missing piece to the puzzle?

Powis KM, Shapiro RL.

J Infect Dis. 2015 Jan 1;211(1):4-7. doi: 10.1093/infdis/jiu397. Epub 2014 Jul 16. No abstract available.

PMID:
25030057
45.

Single-arm evaluation of the AccuCirc device for early infant male circumcision in Botswana.

Plank RM, Wirth KE, Ndubuka NO, Abdullahi R, Nkgau M, Lesetedi C, Powis KM, Mmalane M, Makhema J, Shapiro R, Lockman S.

J Acquir Immune Defic Syndr. 2014 May 1;66(1):1-6. doi: 10.1097/QAI.0000000000000136.

46.

Risk factors for mortality among human immunodeficiency virus-exposed and unexposed infants admitted to a neonatal intensive care unit in Botswana.

Zash RM, Ajose-Popoola O, Stordal K, Souda S, Ogwu A, Dryden-Peterson S, Powis K, Lockman S, Makhema J, Essex M, Shapiro RL.

J Paediatr Child Health. 2014 Mar;50(3):189-95. doi: 10.1111/jpc.12454. Epub 2013 Dec 23.

47.

HIV transmission and 24-month survival in a randomized trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana.

Shapiro RL, Kitch D, Ogwu A, Hughes MD, Lockman S, Powis K, Souda S, Moffat C, Moyo S, McIntosh K, van Widenfelt E, Zwerski S, Mazhani L, Makhema J, Essex M.

AIDS. 2013 Jul 31;27(12):1911-20.

48.

Cotrimoxazole prophylaxis and risk of severe anemia or severe neutropenia in HAART-exposed, HIV-uninfected infants.

Dryden-Peterson S, Jayeoba O, Hughes MD, Jibril H, McIntosh K, Modise TA, Asmelash A, Powis KM, Essex M, Shapiro RL, Lockman S.

PLoS One. 2013 Sep 23;8(9):e74171. doi: 10.1371/journal.pone.0074171. eCollection 2013.

49.

No clinically significant drug-resistance mutations in HIV-1 subtype C-infected women after discontinuation of NRTI-based or PI-based HAART for PMTCT in Botswana.

Souda S, Gaseitsiwe S, Georgette N, Powis K, Moremedi D, Iketleng T, Leidner J, Moffat C, Ogwu A, Lockman S, Moyo S, Mmalane M, Musonda R, Makhema J, Essex M, Shapiro R.

J Acquir Immune Defic Syndr. 2013 Aug 15;63(5):572-7. doi: 10.1097/QAI.0b013e31829308f8.

50.

High viral load and elevated angiogenic markers associated with increased risk of preeclampsia among women initiating highly active antiretroviral therapy in pregnancy in the Mma Bana study, Botswana.

Powis KM, McElrath TF, Hughes MD, Ogwu A, Souda S, Datwyler SA, von Widenfelt E, Moyo S, Nádas M, Makhema J, Machakaire E, Lockman S, Essex M, Shapiro RL.

J Acquir Immune Defic Syndr. 2013 Apr 15;62(5):517-24. doi: 10.1097/QAI.0b013e318286d77e.

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