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Predictive model of response to tafamidis in hereditary ATTR polyneuropathy.

Monteiro C, Mesgazardeh JS, Anselmo J, Fernandes J, Novais M, Rodrigues C, Brighty GJ, Powers DL, Powers ET, Coelho T, Kelly JW.

JCI Insight. 2019 Jun 20;4(12). pii: 126526. doi: 10.1172/jci.insight.126526. eCollection 2019 Jun 20.


X + Y Scheduling in Pediatric Residency: Continuity, Handoffs, and Trainee Experience.

Osborn R, Bullis E, Fenick AM, Powers E, Banker S, Asnes A.

Acad Pediatr. 2019 May 8. pii: S1876-2859(19)30127-5. doi: 10.1016/j.acap.2019.05.001. [Epub ahead of print]


Kinetic versus thermodynamic control of mutational effects on protein homeostasis: A perspective from computational modeling and experiment.

Pobre KFR, Powers DL, Ghosh K, Gierasch LM, Powers ET.

Protein Sci. 2019 Jul;28(7):1324-1339. doi: 10.1002/pro.3639. Epub 2019 May 24.


Trajectories of lower back, upper back, and pelvic girdle pain during pregnancy and early postpartum in primiparous women.

Dunn G, Egger MJ, Shaw JM, Yang J, Bardsley T, Powers E, Nygaard IE.

Womens Health (Lond). 2019 Jan-Dec;15:1745506519842757. doi: 10.1177/1745506519842757.


Early Involvement of the Child Protection Team in the Care of Injured Infants in a Pediatric Emergency Department.

Powers E, Tiyyagura G, Asnes AG, Leventhal JM, Moles R, Christison-Lagay E, Groisberg S, Auerbach M.

J Emerg Med. 2019 Jun;56(6):592-600. doi: 10.1016/j.jemermed.2019.01.030. Epub 2019 Mar 14.


Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing.

Grandjean JMD, Plate L, Morimoto RI, Bollong MJ, Powers ET, Wiseman RL.

ACS Chem Biol. 2019 Apr 19;14(4):784-795. doi: 10.1021/acschembio.9b00134. Epub 2019 Mar 13.


A designed protein binding-pocket to control excited-state intramolecular proton transfer fluorescence.

Lampkin BJ, Monteiro C, Powers ET, Bouc PM, Kelly JW, VanVeller B.

Org Biomol Chem. 2019 Jan 31;17(5):1076-1080. doi: 10.1039/c8ob02673d.


Efficacy and unintended consequences of hard-stop alerts in electronic health record systems: a systematic review.

Powers EM, Shiffman RN, Melnick ER, Hickner A, Sharifi M.

J Am Med Inform Assoc. 2018 Nov 1;25(11):1556-1566. doi: 10.1093/jamia/ocy112.


Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins.

Paxman R, Plate L, Blackwood EA, Glembotski C, Powers ET, Wiseman RL, Kelly JW.

Elife. 2018 Aug 7;7. pii: e37168. doi: 10.7554/eLife.37168.


Expanding the Capacity of Primary Care to Treat Co-morbidities in Children with Autism Spectrum Disorder.

Van Cleave J, Holifield C, Neumeyer AM, Perrin JM, Powers E, Van L, Kuhlthau KA.

J Autism Dev Disord. 2018 Dec;48(12):4222-4230. doi: 10.1007/s10803-018-3630-x.


Effectiveness of a voluntary family befriending service: a mixed methods evaluation using the Donabedian model.

Gentry SV, Powers EFJ, Azim N, Maidrag M.

Public Health. 2018 Jul;160:87-93. doi: 10.1016/j.puhe.2018.03.034. Epub 2018 May 26.


Pervasive, Coordinated Protein-Level Changes Driven by Transcript Isoform Switching during Meiosis.

Cheng Z, Otto GM, Powers EN, Keskin A, Mertins P, Carr SA, Jovanovic M, Brar GA.

Cell. 2018 Feb 22;172(5):910-923.e16. doi: 10.1016/j.cell.2018.01.035.


m6A and eIF2α-ⓟ Team Up to Tackle ATF4 Translation during Stress.

Powers EN, Brar GA.

Mol Cell. 2018 Feb 15;69(4):537-538. doi: 10.1016/j.molcel.2018.01.036.


The unfolded protein response regulator ATF6 promotes mesodermal differentiation.

Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX, Trejo J, Tsang SH, Powers E, Kelly JW, Wiseman RL, Lin JH.

Sci Signal. 2018 Feb 13;11(517). pii: eaan5785. doi: 10.1126/scisignal.aan5785.


Lymphoma and Pathology in Sub-Saharan Africa: Current Approaches and Future Directions.

Tomoka T, Montgomery ND, Powers E, Dhungel BM, Morgan EA, Mulenga M, Gopal S, Fedoriw Y.

Clin Lab Med. 2018 Mar;38(1):91-100. doi: 10.1016/j.cll.2017.10.007. Epub 2017 Dec 13. Review.


Practical Successes in Telepathology Experiences in Africa.

Montgomery ND, Tomoka T, Krysiak R, Powers E, Mulenga M, Kampani C, Chimzimu F, Owino MK, Dhungel BM, Gopal S, Fedoriw Y.

Clin Lab Med. 2018 Mar;38(1):141-150. doi: 10.1016/j.cll.2017.10.011. Epub 2017 Dec 6. Review.


OSTMED.DR®, an Osteopathic Medicine Digital Library.

Fitterling L, Powers E, Vardell E.

Med Ref Serv Q. 2018 Jan-Mar;37(1):74-80. doi: 10.1080/02763869.2018.1404390.


"Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.

Mortenson DE, Brighty GJ, Plate L, Bare G, Chen W, Li S, Wang H, Cravatt BF, Forli S, Powers ET, Sharpless KB, Wilson IA, Kelly JW.

J Am Chem Soc. 2018 Jan 10;140(1):200-210. doi: 10.1021/jacs.7b08366. Epub 2017 Dec 21.


Translation efficiency is maintained at elevated temperature in Escherichia coli.

Morgan GJ, Burkhardt DH, Kelly JW, Powers ET.

J Biol Chem. 2018 Jan 19;293(3):777-793. doi: 10.1074/jbc.RA117.000284. Epub 2017 Nov 28.


Prescription of Panoramic Radiographs in Children: A Health Services Assessment of Current Guidelines.

Yepes JF, Powers E, Downey T, Eckert GJ, Tang Q, Vinson L, Maupomé G.

Pediatr Dent. 2017 Jul 15;39(4):289-296.


The eldercare landscape: Evidence from California.

McMillen DP, Powers ET.

Health Econ. 2017 Sep;26 Suppl 2:139-157. doi: 10.1002/hec.3567.


Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.

Schonhoft JD, Monteiro C, Plate L, Eisele YS, Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S, Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho T, Powers ET, Kelly JW.

Sci Transl Med. 2017 Sep 13;9(407). pii: eaam7621. doi: 10.1126/scitranslmed.aam7621.


Extranodal natural killer/T-cell lymphoma in Malawi: a report of three cases.

Tomoka T, Powers E, van der Gronde T, Amuquandoh A, Dhungel BM, Kampani C, Kamiza S, Montgomery ND, Fedoriw Y, Gopal S.

BMC Cancer. 2017 Sep 6;17(1):633. doi: 10.1186/s12885-017-3612-y.


Using Cooperatively Folded Peptides To Measure Interaction Energies and Conformational Propensities.

Ardejani MS, Powers ET, Kelly JW.

Acc Chem Res. 2017 Aug 15;50(8):1875-1882. doi: 10.1021/acs.accounts.7b00195. Epub 2017 Jul 19.


The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer.

Chen KC, Qu S, Chowdhury S, Noxon IC, Schonhoft JD, Plate L, Powers ET, Kelly JW, Lander GC, Wiseman RL.

EMBO J. 2017 Aug 1;36(15):2296-2309. doi: 10.15252/embj.201695616. Epub 2017 Jun 27.


Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.

Connelly S, Mortenson DE, Choi S, Wilson IA, Powers ET, Kelly JW, Johnson SM.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3441-3449. doi: 10.1016/j.bmcl.2017.05.080. Epub 2017 May 26.


Ligand-promoted protein folding by biased kinetic partitioning.

Hingorani KS, Metcalf MC, Deming DT, Garman SC, Powers ET, Gierasch LM.

Nat Chem Biol. 2017 Apr;13(4):369-371. doi: 10.1038/nchembio.2303. Epub 2017 Feb 20.


Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion.

Penton CM, Badarinarayana V, Prisco J, Powers E, Pincus M, Allen RE, August PR.

Skelet Muscle. 2016 Dec 13;6(1):44.


Cognitive impairment in Parkinson's disease: Association between patient-reported and clinically measured outcomes.

Mills KA, Mari Z, Pontone GM, Pantelyat A, Zhang A, Yoritomo N, Powers E, Brandt J, Dawson TM, Rosenthal LS.

Parkinsonism Relat Disord. 2016 Dec;33:107-114. doi: 10.1016/j.parkreldis.2016.09.025. Epub 2016 Sep 27.


Aspiration Thrombectomy: The Possible Importance of Effective Thrombus Removal and Minimal Residual Thrombus Burden.

Powers ER.

JACC Cardiovasc Interv. 2016 Oct 10;9(19):2012-2013. doi: 10.1016/j.jcin.2016.07.037. No abstract available.


Development of a Data Abstraction Form: Getting What You Need From the Electronic Health Record.

Spratling R, Powers E.

J Pediatr Health Care. 2017 Jan - Feb;31(1):126-130. doi: 10.1016/j.pedhc.2016.07.007. Epub 2016 Aug 26. No abstract available.


Melatonin increases the regularity of cardiac rhythmicity in the Drosophila heart in both wild-type and strains bearing pathogenic mutations.

VanKirk T, Powers E, Dowse HB.

J Comp Physiol B. 2017 Jan;187(1):63-78. doi: 10.1007/s00360-016-1019-8. Epub 2016 Jul 22.


Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.

Plate L, Cooley CB, Chen JJ, Paxman RJ, Gallagher CM, Madoux F, Genereux JC, Dobbs W, Garza D, Spicer TP, Scampavia L, Brown SJ, Rosen H, Powers ET, Walter P, Hodder P, Wiseman RL, Kelly JW.

Elife. 2016 Jul 20;5. pii: e15550. doi: 10.7554/eLife.15550.


The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.

Hsu CH, Park S, Mortenson DE, Foley BL, Wang X, Woods RJ, Case DA, Powers ET, Wong CH, Dyson HJ, Kelly JW.

J Am Chem Soc. 2016 Jun 22;138(24):7636-48. doi: 10.1021/jacs.6b02879. Epub 2016 Jun 14.


Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.

Chen W, Dong J, Plate L, Mortenson DE, Brighty GJ, Li S, Liu Y, Galmozzi A, Lee PS, Hulce JJ, Cravatt BF, Saez E, Powers ET, Wilson IA, Sharpless KB, Kelly JW.

J Am Chem Soc. 2016 Jun 15;138(23):7353-64. doi: 10.1021/jacs.6b02960. Epub 2016 Jun 2.


Current and future treatment of amyloid diseases.

Ankarcrona M, Winblad B, Monteiro C, Fearns C, Powers ET, Johansson J, Westermark GT, Presto J, Ericzon BG, Kelly JW.

J Intern Med. 2016 Aug;280(2):177-202. doi: 10.1111/joim.12506. Epub 2016 May 10. Review.


Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon.

Chen W, Kong L, Connelly S, Dendle JM, Liu Y, Wilson IA, Powers ET, Kelly JW.

ACS Chem Biol. 2016 Jul 15;11(7):1852-61. doi: 10.1021/acschembio.5b01035. Epub 2016 Apr 29.


Use of a FITLINE to Support Families of Overweight and Obese Children in Pediatric Practices.

Pbert L, Druker S, Barton B, Olendzki B, Andersen V, Persuitte G, Bram J, Kurtz S, Powers EM, Crawford S, Geller AC.

Child Obes. 2016 Feb;12(1):33-43. doi: 10.1089/chi.2015.0101. Epub 2016 Jan 20.


Targeting protein aggregation for the treatment of degenerative diseases.

Eisele YS, Monteiro C, Fearns C, Encalada SE, Wiseman RL, Powers ET, Kelly JW.

Nat Rev Drug Discov. 2015 Nov;14(11):759-80. doi: 10.1038/nrd4593. Epub 2015 Sep 4. Review.


Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity.

Murray AN, Chen W, Antonopoulos A, Hanson SR, Wiseman RL, Dell A, Haslam SM, Powers DL, Powers ET, Kelly JW.

Chem Biol. 2015 Aug 20;22(8):1052-62. doi: 10.1016/j.chembiol.2015.06.017. Epub 2015 Jul 16.


Skin Cancer Risk Factors and Preventative Behaviors among United States Military Veterans Deployed to Iraq and Afghanistan.

Powers JG, Patel NA, Powers EM, Mayer JE, Stricklin GP, Geller AC.

J Invest Dermatol. 2015 Nov;135(11):2871-2873. doi: 10.1038/jid.2015.238. Epub 2015 Jun 25. No abstract available.


Angiotensin receptors alter myocardial infarction-induced remodeling of the guinea pig cardiac plexus.

Hardwick JC, Ryan SE, Powers EN, Southerland EM, Ardell JL.

Am J Physiol Regul Integr Comp Physiol. 2015 Jul 15;309(2):R179-88. doi: 10.1152/ajpregu.00004.2015. Epub 2015 May 6.


The potential for harm from alarm fatigue in single-room NICUs.

Walsh MC, Powers E, Fanaroff J.

Acta Paediatr. 2015 May;104(5):436-7. doi: 10.1111/apa.12953. No abstract available.


Individual and collective contributions of chaperoning and degradation to protein homeostasis in E. coli.

Cho Y, Zhang X, Pobre KF, Liu Y, Powers DL, Kelly JW, Gierasch LM, Powers ET.

Cell Rep. 2015 Apr 14;11(2):321-33. doi: 10.1016/j.celrep.2015.03.018. Epub 2015 Apr 2.


Parent preferences for telephone coaching to prevent and manage childhood obesity.

Blaine RE, Pbert L, Geller AC, Powers EM, Mitchell K.

Postgrad Med J. 2015 Apr;91(1074):206-11. doi: 10.1136/postgradmedj-2014-132928. Epub 2015 Mar 26.


Translation: An O-GlcNAc stamp of approval.

Powers ET.

Nat Chem Biol. 2015 May;11(5):307-8. doi: 10.1038/nchembio.1777. Epub 2015 Mar 16. No abstract available.


Data collection using the electronic health record: lessons learned from the chart review process.

Spratling R, Powers E.

J Pediatr Health Care. 2015 May-Jun;29(3):294-6. doi: 10.1016/j.pedhc.2015.01.005. Epub 2015 Feb 9. No abstract available.


Clinical practice guideline executive summary: Labor after cesarean/planned vaginal birth after cesarean.

King VJ, Fontaine PL, Atwood LA, Powers E, Leeman L, Ecker JL, Avery MD, Sakala C, Campos-Outcalt D, Jeffcott-Pera M, Schoof B.

Ann Fam Med. 2015 Jan-Feb;13(1):80-1. doi: 10.1370/afm.1738. No abstract available.


Aging, confidence, and misinformation: recalling information with the cognitive interview.

Dodson CS, Powers E, Lytell M.

Psychol Aging. 2015 Mar;30(1):46-61. doi: 10.1037/a0038492. Epub 2014 Dec 22.


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