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Items: 28


The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells.

Duarte RRR, Bachtel ND, Côtel MC, Lee SH, Selvackadunco S, Watson IA, Hovsepian GA, Troakes C, Breen GD, Nixon DF, Murray RM, Bray NJ, Eleftherianos I, Vernon AC, Powell TR, Srivastava DP.

Biol Psychiatry. 2019 Jul 15;86(2):120-130. doi: 10.1016/j.biopsych.2019.03.977. Epub 2019 Mar 30.


Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility.

Smeeth DM, Dima D, Jones L, Jones I, Craddock N, Owen MJ, Rietschel M, Maier W, Korszun A, Rice JP, Mors O, Preisig M, Uher R, Lewis CM, Thuret S, Powell TR.

Psychoneuroendocrinology. 2019 Aug;106:284-292. doi: 10.1016/j.psyneuen.2019.04.011. Epub 2019 Apr 20.


Associations between childhood maltreatment and inflammatory markers.

Palmos AB, Watson S, Hughes T, Finkelmeyer A, McAllister-Williams RH, Ferrier N, Anderson IM, Nair R, Young AH, Strawbridge R, Cleare AJ, Chung R, Frissa S, Goodwin L, Hotopf M, Hatch SL, Wang H, Collier DA, Thuret S, Breen G, Powell TR.

BJPsych Open. 2019 Jan;5(1):e3. doi: 10.1192/bjo.2018.80.


Inflammatory profiles of severe treatment-resistant depression.

Strawbridge R, Hodsoll J, Powell TR, Hotopf M, Hatch SL, Breen G, Cleare AJ.

J Affect Disord. 2019 Mar 1;246:42-51. doi: 10.1016/j.jad.2018.12.037. Epub 2018 Dec 17.


The polygenic nature of telomere length and the anti-ageing properties of lithium.

Coutts F, Palmos AB, Duarte RRR, de Jong S, Lewis CM, Dima D, Powell TR.

Neuropsychopharmacology. 2019 Mar;44(4):757-765. doi: 10.1038/s41386-018-0289-0. Epub 2018 Dec 18.


Telomere length as a predictor of emotional processing in the brain.

Powell TR, De Jong S, Breen G, Lewis CM, Dima D.

Hum Brain Mapp. 2019 Apr 15;40(6):1750-1759. doi: 10.1002/hbm.24487. Epub 2018 Dec 4.


Genetic Risk for Psychiatric Disorders and Telomere Length.

Palmos AB, Breen G, Goodwin L, Frissa S, Hatch SL, Hotopf M, Thuret S, Lewis CM, Powell TR.

Front Genet. 2018 Oct 16;9:468. doi: 10.3389/fgene.2018.00468. eCollection 2018.


Growth Factor Proteins and Treatment-Resistant Depression: A Place on the Path to Precision.

Pisoni A, Strawbridge R, Hodsoll J, Powell TR, Breen G, Hatch S, Hotopf M, Young AH, Cleare AJ.

Front Psychiatry. 2018 Aug 23;9:386. doi: 10.3389/fpsyt.2018.00386. eCollection 2018.


Translating Schizophrenia Population Genetics Findings to Neurobiological Mechanisms: The Case of KALRN-9.

Powell TR.

Biol Psychiatry. 2018 Mar 15;83(6):e41-e42. doi: 10.1016/j.biopsych.2017.12.011. No abstract available.


Telomere Length and Bipolar Disorder.

Powell TR, Dima D, Frangou S, Breen G.

Neuropsychopharmacology. 2018 Jan;43(2):454. doi: 10.1038/npp.2017.239.


Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood.

Powell TR, Murphy T, Lee SH, Duarte RRR, Lee HA, Smeeth D, Price J, Breen G, Thuret S.

Sci Rep. 2017 Nov 8;7(1):15112. doi: 10.1038/s41598-017-15042-z.


Telomere Length and Bipolar Disorder.

Powell TR, Dima D, Frangou S, Breen G.

Neuropsychopharmacology. 2018 Jan;43(2):445-453. doi: 10.1038/npp.2017.125. Epub 2017 Jun 16. Erratum in: Neuropsychopharmacology. 2018 Jan;43(2):454.


The genome-wide expression effects of escitalopram and its relationship to neurogenesis, hippocampal volume, and antidepressant response.

Powell TR, Murphy T, de Jong S, Lee SH, Tansey KE, Hodgson K, Uher R, Price J, Thuret S, Breen G.

Am J Med Genet B Neuropsychiatr Genet. 2017 Jun;174(4):427-434. doi: 10.1002/ajmg.b.32532. Epub 2017 Apr 10.


Genetic predisposition to advanced biological ageing increases risk for childhood-onset recurrent major depressive disorder in a large UK sample.

Michalek JE, Kepa A, Vincent J, Frissa S, Goodwin L, Hotopf M, Hatch SL, Breen G, Powell TR.

J Affect Disord. 2017 Apr 15;213:207-213. doi: 10.1016/j.jad.2017.01.017. Epub 2017 Feb 16.


Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning.

Powell TR, Murphy T, Lee SH, Price J, Thuret S, Breen G.

J Psychopharmacol. 2017 Mar;31(3):338-345. doi: 10.1177/0269881117691467. Epub 2017 Feb 16.


Assessing the contributions of childhood maltreatment subtypes and depression case-control status on telomere length reveals a specific role of physical neglect.

Vincent J, Hovatta I, Frissa S, Goodwin L, Hotopf M, Hatch SL, Breen G, Powell TR.

J Affect Disord. 2017 Apr 15;213:16-22. doi: 10.1016/j.jad.2017.01.031. Epub 2017 Feb 3.


Transcriptomics and the mechanisms of antidepressant efficacy.

Hodgson K, Tansey KE, Powell TR, Coppola G, Uher R, Zvezdana Dernovšek M, Mors O, Hauser J, Souery D, Maier W, Henigsberg N, Rietschel M, Placentino A, Aitchison KJ, Craig IW, Farmer AE, Breen G, McGuffin P, Dobson R.

Eur Neuropsychopharmacol. 2016 Jan;26(1):105-112. doi: 10.1016/j.euroneuro.2015.10.009. Epub 2015 Nov 12.


Neurological involvement and characterization in acquired hemophagocytic lymphohistiocytosis in adulthood.

Gratton SM, Powell TR, Theeler BJ, Hawley JS, Amjad FS, Tornatore C.

J Neurol Sci. 2015 Oct 15;357(1-2):136-42. doi: 10.1016/j.jns.2015.07.017. Epub 2015 Jul 16.


Mood-stabilizers differentially affect housekeeping gene expression in human cells.

Powell TR, Powell-Smith G, Haddley K, Mcguffin P, Quinn J, Schalkwyk LC, Farmer AE, D'Souza UM.

Int J Methods Psychiatr Res. 2014 Jun;23(2):279-88. doi: 10.1002/mpr.1435. Epub 2014 Feb 12.


Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients.

Powell TR, McGuffin P, D'Souza UM, Cohen-Woods S, Hosang GM, Martin C, Matthews K, Day RK, Farmer AE, Tansey KE, Schalkwyk LC.

PLoS One. 2014 Mar 11;9(3):e91076. doi: 10.1371/journal.pone.0091076. eCollection 2014.


The inflammatory cytokines: molecular biomarkers for major depressive disorder?

Martin C, Tansey KE, Schalkwyk LC, Powell TR.

Biomark Med. 2015;9(2):169-80. doi: 10.2217/bmm.14.29. Epub 2014 Feb 14. Review.


DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP.

Powell TR, Smith RG, Hackinger S, Schalkwyk LC, Uher R, McGuffin P, Mill J, Tansey KE.

Transl Psychiatry. 2013 Sep 3;3:e300. doi: 10.1038/tp.2013.73.


Allele-specific expression of the serotonin transporter and its transcription factors following lamotrigine treatment in vitro.

D'Souza UM, Powell-Smith G, Haddley K, Powell TR, Bubb VJ, Price T, McGuffin P, Quinn JP, Farmer AE.

Am J Med Genet B Neuropsychiatr Genet. 2013 Jul;162B(5):474-83. doi: 10.1002/ajmg.b.32178. Epub 2013 Jun 14.


ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway.

Powell TR, Tansey KE, Breen G, Farmer AE, Craig IW, Uher R, McGuffin P, D'Souza UM, Schalkwyk LC.

J Psychopharmacol. 2013 Jul;27(7):609-15. doi: 10.1177/0269881113490329. Epub 2013 May 29.


Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response.

Powell TR, Schalkwyk LC, Heffernan AL, Breen G, Lawrence T, Price T, Farmer AE, Aitchison KJ, Craig IW, Danese A, Lewis C, McGuffin P, Uher R, Tansey KE, D'Souza UM.

Eur Neuropsychopharmacol. 2013 Sep;23(9):1105-14. doi: 10.1016/j.euroneuro.2012.09.009. Epub 2012 Nov 9.


Depression-Related Behavioral Tests.

Powell TR, Fernandes C, Schalkwyk LC.

Curr Protoc Mouse Biol. 2012 Jun 1;2(2):119-27. doi: 10.1002/9780470942390.mo110176.


Breast and cervical cancer disparities in SC: African-American perspective.

Powell TR.

J S C Med Assoc. 2006 Aug;102(7):240. No abstract available.


HLA-Bw44 and HLA-DRw4 in male Sjögren's syndrome patients with associated rheumatoid arthritis.

Powell TR, Michalski JP, McCombs CC, Danilovs JA, Terasaki PI, Park MS, Flood T, Boone WB.

Clin Immunol Immunopathol. 1980 Nov;17(3):463-8. No abstract available.


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