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Letter: immune checkpoint inhibitor-induced colitis-shouldn't we be checking more often?

Samaan MA, Powell N, Irving PM.

Aliment Pharmacol Ther. 2019 Aug;50(4):472-473. doi: 10.1111/apt.15393. No abstract available.


Genetic and Inflammatory Biomarkers Classify Small Intestine Inflammation in Asymptomatic First-degree Relatives of Patients With Crohn's Disease.

Taylor KM, Hanscombe KB, Prescott NJ, Iniesta R, Traylor M, Taylor NS, Fong S, Powell N, Irving PM, Anderson SH, Mathew CG, Lewis CM, Sanderson JD.

Clin Gastroenterol Hepatol. 2019 Jun 14. pii: S1542-3565(19)30643-3. doi: 10.1016/j.cgh.2019.05.061. [Epub ahead of print]


Can patients in hospital become guardians of antimicrobial stewardship?

Wilcock M, Powell N.

Drug Ther Bull. 2019 Aug;57(8):115-116. doi: 10.1136/dtb.2019.000017. Epub 2019 Jun 10. No abstract available.


Antimicrobial stewardship and the hospital nurse and midwife: how do they perceive their role?

Wilcock M, Powell N, Underwood F.

Eur J Hosp Pharm. 2019 Mar;26(2):89-92. doi: 10.1136/ejhpharm-2017-001312. Epub 2017 Sep 27.


Home Healthcare Visits Following Hospital Discharge: Does the Timing of Visits Affect 30-Day Hospital Readmission Rates for Heart Failure Patients?

Strano A, Briggs A, Powell N, Brockman J, Taylor J, Butler A, Soendker M, Upschulte S, Long E, Wills R, Ward-Smith P.

Home Healthc Now. 2019 May/Jun;37(3):152-157. doi: 10.1097/NHH.0000000000000740.


Group 3 ILCs: Peacekeepers or Troublemakers? What's Your Gut Telling You?!

Pantazi E, Powell N.

Front Immunol. 2019 Apr 5;10:676. doi: 10.3389/fimmu.2019.00676. eCollection 2019. Review.


Learning bioinspired joint geometry from motion capture data of bat flight.

Bender M, Guo J, Powell N, Kurdila A, Müller R.

Bioinspir Biomim. 2019 Apr 10;14(3):036013. doi: 10.1088/1748-3190/ab0fba.


Topical beclometasone dipropionate in the management of immune checkpoint inhibitor-induced microscopic colitis.

Ibraheim H, Green M, Papa S, Powell N.

BMJ Case Rep. 2019 Apr 3;12(4). pii: e226481. doi: 10.1136/bcr-2018-226481.


Cognitive Behavioral Intervention for Youth at Risk for Conduct Problems: Future Directions.

Lochman JE, Boxmeyer CL, Kassing FL, Powell NP, Stromeyer SL.

J Clin Child Adolesc Psychol. 2019 Mar 20:1-12. doi: 10.1080/15374416.2019.1567349. [Epub ahead of print]


Out of Sight, Out of Mind: The Limitations of the Hospital Anxiety and Depression Scale in Inflammatory Bowel Disease.

Moulton CD, Hopkins CWP, Mohamedali Z, Powell N.

Inflamm Bowel Dis. 2019 Jul 17;25(8):e100. doi: 10.1093/ibd/izz034. No abstract available.


Depression in inflammatory bowel disease: risk factor, prodrome or extraintestinal manifestation?

Moulton CD, Norton C, Powell N, Mohamedali Z, Hopkins CWP.

Gut. 2019 Feb 26. pii: gutjnl-2019-318444. doi: 10.1136/gutjnl-2019-318444. [Epub ahead of print] No abstract available.


Depressive symptoms in inflammatory bowel disease: an extraintestinal manifestation of inflammation?

Moulton CD, Pavlidis P, Norton C, Norton S, Pariante C, Hayee B, Powell N.

Clin Exp Immunol. 2019 Sep;197(3):308-318. doi: 10.1111/cei.13276. Epub 2019 Mar 11. Review.


Study the Longitudinal in vivo and Cross-Sectional ex vivo Brain Volume Difference for Disease Progression and Treatment Effect on Mouse Model of Tauopathy Using Automated MRI Structural Parcellation.

Ma D, Holmes HE, Cardoso MJ, Modat M, Harrison IF, Powell NM, O'Callaghan JM, Ismail O, Johnson RA, O'Neill MJ, Collins EC, Beg MF, Popuri K, Lythgoe MF, Ourselin S.

Front Neurosci. 2019 Jan 24;13:11. doi: 10.3389/fnins.2019.00011. eCollection 2019.


Challenging the supremacy of intravenous antibiotics.

Powell N, Wilcock M.

Drug Ther Bull. 2019 Jan;57(1):2. doi: 10.1136/dtb.2018.000042. No abstract available.


Sensitivity to inhibition of DNA repair by Olaparib in novel oropharyngeal cancer cell lines infected with Human Papillomavirus.

Pirotte EF, Holzhauser S, Owens D, Quine S, Al-Hussaini A, Christian AD, Giles PJ, Man ST, Evans M, Powell NG.

PLoS One. 2018 Dec 13;13(12):e0207934. doi: 10.1371/journal.pone.0207934. eCollection 2018.


Impact of penicillin allergy records on carbapenem prescribing: an observational retrospective cohort study.

Powell N, West R, Sandoe J.

J Hosp Infect. 2019 Apr;101(4):467-470. doi: 10.1016/j.jhin.2018.11.020. Epub 2018 Dec 6.


Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa.

Povoleri GAM, Nova-Lamperti E, Scottà C, Fanelli G, Chen YC, Becker PD, Boardman D, Costantini B, Romano M, Pavlidis P, McGregor R, Pantazi E, Chauss D, Sun HW, Shih HY, Cousins DJ, Cooper N, Powell N, Kemper C, Pirooznia M, Laurence A, Kordasti S, Kazemian M, Lombardi G, Afzali B.

Nat Immunol. 2018 Dec;19(12):1403-1414. doi: 10.1038/s41590-018-0230-z. Epub 2018 Nov 5.


T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function.

Garrido-Mesa N, Schroeder JH, Stolarczyk E, Gallagher AL, Lo JW, Bailey C, Campbell L, Sexl V, MacDonald TT, Howard JK, Grencis RK, Powell N, Lord GM.

Mucosal Immunol. 2019 Jan;12(1):51-63. doi: 10.1038/s41385-018-0092-6. Epub 2018 Oct 24.


Direct solid state NMR observation of the 105Pd nucleus in inorganic compounds and palladium metal systems.

Hooper TJN, Partridge TA, Rees GJ, Keeble DS, Powell NA, Smith ME, Mikheenko IP, Macaskie LE, Bishop PT, Hanna JV.

Phys Chem Chem Phys. 2018 Nov 7;20(41):26734-26743. doi: 10.1039/c8cp02594k. Epub 2018 Oct 16.


Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.

Arbore G, West EE, Rahman J, Le Friec G, Niyonzima N, Pirooznia M, Tunc I, Pavlidis P, Powell N, Li Y, Liu P, Servais A, Couzi L, Fremeaux-Bacchi V, Placais L, Ferraro A, Walsh PR, Kavanagh D, Afzali B, Lavender P, Lachmann HJ, Kemper C.

Nat Commun. 2018 Oct 10;9(1):4186. doi: 10.1038/s41467-018-06706-z.


Science in Focus: The Microbiome and Cancer Therapy.

Alexander JL, Kohoutova D, Powell N.

Clin Oncol (R Coll Radiol). 2019 Jan;31(1):1-4. doi: 10.1016/j.clon.2018.09.004. Epub 2018 Oct 6. No abstract available.


The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease.

Harrison IF, Powell NM, Dexter DT.

J Neurochem. 2019 Jan;148(1):136-156. doi: 10.1111/jnc.14599. Epub 2018 Nov 26.


Gender neutral vaccination against HPV.

Powell N, Hibbitts S, Evans M.

BMJ. 2018 Sep 17;362:k3837. doi: 10.1136/bmj.k3837. No abstract available.


Identifying antibiotic stewardship interventions to meet the NHS England CQUIN: an evaluation of antibiotic -prescribing against published evidence-based antibiotic audit tools .

Powell N, McGraw-Allen K, Menzies A, Peet B, Simmonds C, Wild A.

Clin Med (Lond). 2018 Aug;18(4):276-281. doi: 10.7861/clinmedicine.18-4-276.


Development of a Global Health Milestones Tool for Learners in Emergency Medicine: A Pilot Project.

Douglass KA, Jacquet GA, Hayward AS, Dreifuss BA, Tupesis JP, Acerra J, Bloem C, Brenner J, DeVos E, Douglass K, Dreifuss B, Hayward AS, Hilbert SL, Jacquet GA, Lin J, Muck A, Nasser S, Oteng R, Powell NN, Rybarczyk MM, Schmidt J, Svenson J, Tupesis JP, Yoder K.

AEM Educ Train. 2017 Sep 11;1(4):269-279. doi: 10.1002/aet2.10046. eCollection 2017 Oct.


Golimumab: early experience and medium-term outcomes from two UK tertiary IBD centres.

Samaan MA, Pavlidis P, Digby-Bell J, Johnston EL, Dhillon A, Paramsothy R, Akintimehin AO, Medcalf L, Chung-Faye G, DuBois P, Koumoutsos I, Powell N, Anderson SHC, Sanderson J, Hayee BH, Irving PM.

Frontline Gastroenterol. 2018 Jul;9(3):221-231. doi: 10.1136/flgastro-2017-100895. Epub 2017 Oct 11.


The effects of repeated automated plasmapheresis in goats (Capra hircus) in response to vaccination with purified influenza hemagglutinin proteins.

Taylor WD Jr, Langham GL, Weed JL, Rowe T, Song W, Isenberg KA, Xu X, Wentworth DE, Lathrop G, Powell N.

PLoS One. 2018 Jun 13;13(6):e0195903. doi: 10.1371/journal.pone.0195903. eCollection 2018.


A definition of free sugars for the UK.

Swan GE, Powell NA, Knowles BL, Bush MT, Levy LB.

Public Health Nutr. 2018 Jun;21(9):1636-1638. doi: 10.1017/S136898001800085X. Epub 2018 Mar 28.


Gastrointestinal toxicity of immune checkpoint inhibitors: from mechanisms to management.

Samaan MA, Pavlidis P, Papa S, Powell N, Irving PM.

Nat Rev Gastroenterol Hepatol. 2018 Apr;15(4):222-234. doi: 10.1038/nrgastro.2018.14. Epub 2018 Mar 7. Review.


Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction.

Fricker M, Goggins BJ, Mateer S, Jones B, Kim RY, Gellatly SL, Jarnicki AG, Powell N, Oliver BG, Radford-Smith G, Talley NJ, Walker MM, Keely S, Hansbro PM.

JCI Insight. 2018 Feb 8;3(3). pii: 94040. doi: 10.1172/jci.insight.94040. eCollection 2018 Feb 8.


Recurrence of vulval intraepithelial neoplasia following treatment with cidofovir or imiquimod: results from a multicentre, randomised, phase II trial (RT3VIN).

Hurt CN, Jones S, Madden TA, Fiander A, Nordin AJ, Naik R, Powell N, Carucci M, Tristram A.

BJOG. 2018 Aug;125(9):1171-1177. doi: 10.1111/1471-0528.15124. Epub 2018 Feb 9.


Toward Tailored Interventions: Sympathetic and Parasympathetic Functioning Predicts Responses to an Intervention for Conduct Problems Delivered in Two Formats.

Glenn AL, Lochman JE, Dishion T, Powell NP, Boxmeyer C, Kassing F, Qu L, Romero D.

Prev Sci. 2019 Jan;20(1):30-40. doi: 10.1007/s11121-017-0859-0.


In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis.

Colgan N, Ganeshan B, Harrison IF, Ismail O, Holmes HE, Wells JA, Powell NM, O'Callaghan JM, O'Neill MJ, Murray TK, Ahmed Z, Collins EC, Johnson RA, Groves A, Lythgoe MF.

Front Neurosci. 2017 Nov 6;11:599. doi: 10.3389/fnins.2017.00599. eCollection 2017.


Advances in mesenchymal stromal cell therapy in the management of Crohn's disease.

Ibraheim H, Giacomini C, Kassam Z, Dazzi F, Powell N.

Expert Rev Gastroenterol Hepatol. 2018 Feb;12(2):141-153. doi: 10.1080/17474124.2018.1393332. Epub 2017 Nov 2. Review.


Vedolizumab: early experience and medium-term outcomes from two UK tertiary IBD centres.

Samaan MA, Pavlidis P, Johnston E, Warner B, Digby-Bell J, Koumoutsos I, Fong S, Goldberg R, Patel K, Gulati S, Medcalf L, Sastrillo M, Brown-Clarke C, Bidewell-Sullivan J, Forsyth K, Lee E, Stanton A, Duncan J, Chung-Faye G, Dubois P, Powell N, Anderson S, Sanderson J, Hayee B, Irving PM.

Frontline Gastroenterol. 2017 Jul;8(3):196-202. doi: 10.1136/flgastro-2016-100720. Epub 2016 Aug 10.


Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease.

O'Callaghan J, Holmes H, Powell N, Wells JA, Ismail O, Harrison IF, Siow B, Johnson R, Ahmed Z, Fisher A, Meftah S, O'Neill MJ, Murray TK, Collins EC, Shmueli K, Lythgoe MF.

Neuroimage. 2017 Oct 1;159:334-345. doi: 10.1016/j.neuroimage.2017.08.003. Epub 2017 Aug 4.


An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment.

Halim L, Romano M, McGregor R, Correa I, Pavlidis P, Grageda N, Hoong SJ, Yuksel M, Jassem W, Hannen RF, Ong M, Mckinney O, Hayee B, Karagiannis SN, Powell N, Lechler RI, Nova-Lamperti E, Lombardi G.

Cell Rep. 2017 Jul 18;20(3):757-770. doi: 10.1016/j.celrep.2017.06.079.


Human Papillomavirus DNA Methylation Predicts Response to Treatment Using Cidofovir and Imiquimod in Vulval Intraepithelial Neoplasia 3.

Jones SEF, Hibbitts S, Hurt CN, Bryant D, Fiander AN, Powell N, Tristram AJ.

Clin Cancer Res. 2017 Sep 15;23(18):5460-5468. doi: 10.1158/1078-0432.CCR-17-0040. Epub 2017 Jun 9.


Developing a local antimicrobial resistance action plan: the Cornwall One Health Antimicrobial Resistance Group.

Powell N, Davidson I, Yelling P, Collinson A, Pollard A, Johnson L, Gibson N, Taylor J, Wisner K, Gaze W, South J, Ashiru-Oredope D.

J Antimicrob Chemother. 2017 Sep 1;72(9):2661-2665. doi: 10.1093/jac/dkx164.


Daily Moderate Exercise Is Beneficial and Social Stress Is Detrimental to Disease Pathology in Murine Lupus Nephritis.

Aqel SI, Hampton JM, Bruss M, Jones KT, Valiente GR, Wu LC, Young MC, Willis WL, Ardoin S, Agarwal S, Bolon B, Powell N, Sheridan J, Schlesinger N, Jarjour WN, Young NA.

Front Physiol. 2017 Apr 26;8:236. doi: 10.3389/fphys.2017.00236. eCollection 2017.


Vedolizumab: toward a personalized therapy paradigm for people with ulcerative colitis.

Dart RJ, Samaan MA, Powell N, Irving PM.

Clin Exp Gastroenterol. 2017 Mar 3;10:57-66. doi: 10.2147/CEG.S110547. eCollection 2017. Review.


Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy.

Holmes HE, Powell NM, Ma D, Ismail O, Harrison IF, Wells JA, Colgan N, O'Callaghan JM, Johnson RA, Murray TK, Ahmed Z, Heggenes M, Fisher A, Cardoso MJ, Modat M, O'Neill MJ, Collins EC, Fisher EM, Ourselin S, Lythgoe MF.

Front Neuroinform. 2017 Mar 31;11:20. doi: 10.3389/fninf.2017.00020. eCollection 2017.


Recent advances in gut immunology.

Powell N, MacDonald TT.

Parasite Immunol. 2017 Jun;39(6). doi: 10.1111/pim.12430. Review.


Pharmacokinetic Profiles of Meloxicam and Sustained-release Buprenorphine in Prairie Dogs (Cynomys ludovicianus).

Cary CD, Lukovsky-Akhsanov NL, Gallardo-Romero NF, Tansey CM, Ostergaard SD, Taylor WD Jr, Morgan CN, Powell N, Lathrop GW, Hutson CL.

J Am Assoc Lab Anim Sci. 2017 Mar 1;56(2):160-165.


Oxytocin Receptor Gene Variant Interacts with Intervention Delivery Format in Predicting Intervention Outcomes for Youth with Conduct Problems.

Glenn AL, Lochman JE, Dishion T, Powell NP, Boxmeyer C, Qu L.

Prev Sci. 2018 Jan;19(1):38-48. doi: 10.1007/s11121-017-0777-1.


The mucosal immune system: master regulator of bidirectional gut-brain communications.

Powell N, Walker MM, Talley NJ.

Nat Rev Gastroenterol Hepatol. 2017 Mar;14(3):143-159. doi: 10.1038/nrgastro.2016.191. Epub 2017 Jan 18. Review.


Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation.

Clayton EL, Mancuso R, Nielsen TT, Mizielinska S, Holmes H, Powell N, Norona F, Larsen JO, Milioto C, Wilson KM, Lythgoe MF, Ourselin S, Nielsen JE, Johannsen P, Holm I, Collinge J; FReJA, Oliver PL, Gomez-Nicola D, Isaacs AM.

Hum Mol Genet. 2017 Mar 1;26(5):873-887. doi: 10.1093/hmg/ddx003.


Variation in Response to Evidence-Based Group Preventive Intervention for Disruptive Behavior Problems: A View from 938 Coping Power Sessions.

Lochman JE, Dishion TJ, Boxmeyer CL, Powell NP, Qu L.

J Abnorm Child Psychol. 2017 Oct;45(7):1271-1284. doi: 10.1007/s10802-016-0252-7.


Pre-Post Tornado Effects on Aggressive Children's Psychological and Behavioral Adjustment Through One-Year Postdisaster.

Lochman JE, Vernberg E, Powell NP, Boxmeyer CL, Jarrett M, McDonald K, Qu L, Hendrickson M, Kassing F.

J Clin Child Adolesc Psychol. 2017 Jan-Feb;46(1):136-149. doi: 10.1080/15374416.2016.1228460. Epub 2016 Nov 14.


HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology.

Schache AG, Powell NG, Cuschieri KS, Robinson M, Leary S, Mehanna H, Rapozo D, Long A, Cubie H, Junor E, Monaghan H, Harrington KJ, Nutting CM, Schick U, Lau AS, Upile N, Sheard J, Brougham K, West CM, Oguejiofor K, Thomas S, Ness AR, Pring M, Thomas GJ, King EV, McCance DJ, James JA, Moran M, Sloan P, Shaw RJ, Evans M, Jones TM.

Cancer Res. 2016 Nov 15;76(22):6598-6606. doi: 10.1158/0008-5472.CAN-16-0633. Epub 2016 Aug 28.

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