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Items: 1 to 50 of 307

1.

In Vitro Assessment of Putative PD-1/PD-L1 Inhibitors: Suggestions of an Alternative Mode of Action.

Blevins DJ, Hanley R, Bolduc T, Powell DA, Gignac M, Walker K, Carr MD, Hof F, Wulff JE.

ACS Med Chem Lett. 2019 Jul 2;10(8):1187-1192. doi: 10.1021/acsmedchemlett.9b00221. eCollection 2019 Aug 8.

PMID:
31413804
2.

The Commensal Neisseria musculi Modulates Host Innate Immunity To Promote Oral Colonization.

Powell DA, Ma M, So M, Frelinger JA.

Immunohorizons. 2018 Oct 31;2(9):305-313. doi: 10.4049/immunohorizons.1800070.

PMID:
31022695
3.

Synthetic polymer coatings diminish chronic inflammation risk in large ECM-based materials.

Bracaglia LG, Winston S, Powell DA, Fisher JP.

J Biomed Mater Res A. 2019 Mar;107(3):494-504. doi: 10.1002/jbm.a.36564. Epub 2018 Nov 22.

PMID:
30565857
4.

Bandwidth and size limits of achromatic printed-circuit metasurfaces.

Fathnan AA, Powell DA.

Opt Express. 2018 Oct 29;26(22):29440-29450. doi: 10.1364/OE.26.029440.

PMID:
30470107
5.

Viable spores of Coccidioides posadasii Δcps1 are required for vaccination and provide long lasting immunity.

Shubitz LF, Powell DA, Trinh HT, Lewis ML, Orbach MJ, Frelinger JA, Galgiani JN.

Vaccine. 2018 May 31;36(23):3375-3380. doi: 10.1016/j.vaccine.2018.04.026. Epub 2018 Apr 30.

6.

Adaptive Immunity to Francisella tularensis and Considerations for Vaccine Development.

Roberts LM, Powell DA, Frelinger JA.

Front Cell Infect Microbiol. 2018 Apr 6;8:115. doi: 10.3389/fcimb.2018.00115. eCollection 2018. Review.

7.

Three dimensional extrusion printing induces polymer molecule alignment and cell organization within engineered cartilage.

Guo T, Ringel JP, Lim CG, Bracaglia LG, Noshin M, Baker HB, Powell DA, Fisher JP.

J Biomed Mater Res A. 2018 Aug;106(8):2190-2199. doi: 10.1002/jbm.a.36426. Epub 2018 Apr 30.

8.

A Natural Mouse Model for Neisseria Colonization.

Ma M, Powell DA, Weyand NJ, Rhodes KA, Rendón MA, Frelinger JA, So M.

Infect Immun. 2018 Apr 23;86(5). pii: e00839-17. doi: 10.1128/IAI.00839-17. Print 2018 May.

9.

Ultrathin tunable terahertz absorber based on MEMS-driven metamaterial.

Liu M, Susli M, Silva D, Putrino G, Kala H, Fan S, Cole M, Faraone L, Wallace VP, Padilla WJ, Powell DA, Shadrivov IV, Martyniuk M.

Microsyst Nanoeng. 2017 Aug 28;3:17033. doi: 10.1038/micronano.2017.33. eCollection 2017.

10.

Efficacy of Resistance to Francisella Imparted by ITY/NRAMP/SLC11A1 Depends on Route of Infection.

Powell DA, Frelinger JA.

Front Immunol. 2017 Mar 15;8:206. doi: 10.3389/fimmu.2017.00206. eCollection 2017.

11.

Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIV.

Schreier JD, Embrey MW, Raheem IT, Barbe G, Campeau LC, Dubost D, McCabe Dunn J, Grobler J, Hartingh TJ, Hazuda DJ, Klein D, Miller MD, Moore KP, Nguyen N, Pajkovic N, Powell DA, Rada V, Sanders JM, Sisko J, Steele TG, Wai J, Walji A, Xu M, Coleman PJ.

Bioorg Med Chem Lett. 2017 May 1;27(9):2038-2046. doi: 10.1016/j.bmcl.2017.02.039. Epub 2017 Feb 20.

PMID:
28285916
12.

Strong terahertz absorption in all-dielectric Huygens' metasurfaces.

Cole MA, Powell DA, Shadrivov IV.

Nanotechnology. 2016 Oct 21;27(42):424003. Epub 2016 Sep 19.

PMID:
27641690
13.

Elastic metamaterials for tuning circular polarization of electromagnetic waves.

Zárate Y, Babaee S, Kang SH, Neshev DN, Shadrivov IV, Bertoldi K, Powell DA.

Sci Rep. 2016 Jun 20;6:28273. doi: 10.1038/srep28273.

14.

Electrically tunable terahertz metamaterials with embedded large-area transparent thin-film transistor arrays.

Xu WZ, Ren FF, Ye J, Lu H, Liang L, Huang X, Liu M, Shadrivov IV, Powell DA, Yu G, Jin B, Zhang R, Zheng Y, Tan HH, Jagadish C.

Sci Rep. 2016 Mar 22;6:23486. doi: 10.1038/srep23486.

15.

Correction to Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.

Raheem IT, Walji AM, Klein D, Sanders JM, Powell DA, Abeywickrema P, Barbe G, Bennet A, Childers K, Christensen M, Clas SD, Dubost D, Embrey M, Grobler J, Hafey MJ, Hartingh TJ, Hazuda DJ, Kuethe JT, McCabe Dunn J, Miller MD, Moore KP, Nolting A, Pajkovic N, Patel S, Peng Z, Rada V, Rearden P, Schreier JD, Sisko J, Steele TG, Truchon JF, Wai J, Xu M, Coleman PJ.

J Med Chem. 2016 Jan 14;59(1):486. doi: 10.1021/acs.jmedchem.5b01957. Epub 2015 Dec 28. No abstract available.

PMID:
26709958
16.

Tunable Meta-Liquid Crystals.

Liu M, Fan K, Padilla W, Powell DA, Zhang X, Shadrivov IV.

Adv Mater. 2016 Feb 24;28(8):1553-8. doi: 10.1002/adma.201504924. Epub 2015 Dec 8.

PMID:
26644296
17.

Distinct innate responses are induced by attenuated Salmonella enterica serovar Typhimurium mutants.

Powell DA, Roberts LM, Ledvina HE, Sempowski GD, Curtiss R 3rd, Frelinger JA.

Cell Immunol. 2016 Jan;299:42-9. doi: 10.1016/j.cellimm.2015.10.002. Epub 2015 Oct 22.

18.

Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.

Raheem IT, Walji AM, Klein D, Sanders JM, Powell DA, Abeywickrema P, Barbe G, Bennet A, Childers K, Christensen M, Clas SD, Dubost D, Embrey M, Grobler J, Hafey MJ, Hartingh TJ, Hazuda DJ, Kuethe JT, McCabe Dunn J, Miller MD, Moore KP, Nolting A, Pajkovic N, Patel S, Peng Z, Rada V, Rearden P, Schreier JD, Sisko J, Steele TG, Truchon JF, Wai J, Xu M, Coleman PJ.

J Med Chem. 2015 Oct 22;58(20):8154-65. doi: 10.1021/acs.jmedchem.5b01037. Epub 2015 Oct 8. Erratum in: J Med Chem. 2016 Jan 14;59(1):486. Childers, Karla [added]; Christensen, Melodie [added]; Kuethe, Jeffrey T. [added]; McCabe Dunn, Jamie [added]; Nolting, Andrew [added]; Peng, Zuihui [corrected].

PMID:
26397965
19.

Site-specific activity of the acyltransferases HtrB1 and HtrB2 in Pseudomonas aeruginosa lipid A biosynthesis.

Hittle LE, Powell DA, Jones JW, Tofigh M, Goodlett DR, Moskowitz SM, Ernst RK.

Pathog Dis. 2015 Nov;73(8):ftv053. doi: 10.1093/femspd/ftv053. Epub 2015 Jul 29.

20.

Tuberculin skin testing and T-SPOT.TB in internationally adopted children.

Spicer KB, Turner J, Wang SH, Koranyi K, Powell DA.

Pediatr Infect Dis J. 2015 Jun;34(6):599-603. doi: 10.1097/INF.0000000000000680.

PMID:
25973937
21.

The prrF-encoded small regulatory RNAs are required for iron homeostasis and virulence of Pseudomonas aeruginosa.

Reinhart AA, Powell DA, Nguyen AT, O'Neill M, Djapgne L, Wilks A, Ernst RK, Oglesby-Sherrouse AG.

Infect Immun. 2015 Mar;83(3):863-75. doi: 10.1128/IAI.02707-14. Epub 2014 Dec 15.

22.

Spontaneous chiral symmetry breaking in metamaterials.

Liu M, Powell DA, Shadrivov IV, Lapine M, Kivshar YS.

Nat Commun. 2014 Jul 18;5:4441. doi: 10.1038/ncomms5441.

PMID:
25033837
23.

Identification of a protein phosphatase 2A family member that regulates cell cycle progression in Trypanosoma brucei.

Rothberg KG, Jetton N, Hubbard JG, Powell DA, Pandarinath V, Ruben L.

Mol Biochem Parasitol. 2014 Mar-Apr;194(1-2):48-52. doi: 10.1016/j.molbiopara.2014.04.006. Epub 2014 Apr 26.

PMID:
24780109
24.

Completion of Latent Tuberculosis Therapy in Children: Impact of Country of Origin and Neighborhood Clinics.

Spicer KB, Perkins L, DeJesus B, Wang SH, Powell DA.

J Pediatric Infect Dis Soc. 2013 Dec;2(4):312-9. doi: 10.1093/jpids/pit015. Epub 2013 Apr 3.

PMID:
26619494
25.

Surveys suck: Consumer preferences when purchasing genetically engineered foods.

Powell DA.

GM Crops Food. 2013 Jul-Dec;4(3):195-201. doi: 10.4161/gmcr.26777. Epub 2013 Nov 12. Review.

PMID:
24281042
26.

An overview of patented small molecule stearoyl coenzyme-A desaturase inhibitors (2009 - 2013).

Powell DA.

Expert Opin Ther Pat. 2014 Feb;24(2):155-75. doi: 10.1517/13543776.2014.851669. Epub 2013 Nov 20. Review.

PMID:
24251719
27.

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.

Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA.

Science. 2013 Sep 13;341(6151):1250-3. doi: 10.1126/science.1240988.

28.

Flexible helices for nonlinear metamaterials.

Slobozhanyuk AP, Lapine M, Powell DA, Shadrivov IV, Kivshar YS, McPhedran RC, Belov PA.

Adv Mater. 2013 Jul 5;25(25):3409-12. doi: 10.1002/adma.201300840. Epub 2013 May 21.

PMID:
23696243
29.

Evaluation of a hand hygiene campaign in outpatient health care clinics.

Kukanich KS, Kaur R, Freeman LC, Powell DA.

Am J Nurs. 2013 Mar;113(3):36-42; quiz 43-4. doi: 10.1097/01.NAJ.0000427878.80053.f7.

PMID:
23411579
30.

Turning up Francisella pathogenesis: the LPS thermostat.

Powell DA, Li Y, Ernst RK.

Virulence. 2012 Nov 15;3(7):594-6. doi: 10.4161/viru.22496. Epub 2012 Nov 15. No abstract available.

31.

Investigating the potential benefits of on-site food safety training for Folklorama, a temporary food service event.

Mancini R, Murray L, Chapman BJ, Powell DA.

J Food Prot. 2012 Oct;75(10):1829-34. doi: 10.4315/0362-028X.JFP-11-564.

PMID:
23043832
32.

Spatial dispersion of multilayer fishnet metamaterials.

Kruk SS, Powell DA, Minovich A, Neshev DN, Kivshar YS.

Opt Express. 2012 Jul 2;20(14):15100-5. doi: 10.1364/OE.20.015100.

PMID:
22772207
33.

LPS remodeling is an evolved survival strategy for bacteria.

Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8716-21. doi: 10.1073/pnas.1202908109. Epub 2012 May 14. Erratum in: Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13877.

34.

Metamaterials with conformational nonlinearity.

Lapine M, Shadrivov IV, Powell DA, Kivshar YS.

Sci Rep. 2011;1:138. doi: 10.1038/srep00138. Epub 2011 Nov 2.

35.

Discrete dissipative localized modes in nonlinear magnetic metamaterials.

Rosanov NN, Vysotina NV, Shatsev AN, Shadrivov IV, Powell DA, Kivshar YS.

Opt Express. 2011 Dec 19;19(27):26500-6. doi: 10.1364/OE.19.026500.

PMID:
22274234
36.

Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses.

Kanistanon D, Powell DA, Hajjar AM, Pelletier MR, Cohen IE, Way SS, Skerrett SJ, Wang X, Raetz CR, Ernst RK.

Infect Immun. 2012 Mar;80(3):943-51. doi: 10.1128/IAI.06109-11. Epub 2012 Jan 3.

37.

Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series.

Lachance N, Gareau Y, Guiral S, Huang Z, Isabel E, Leclerc JP, Léger S, Martins E, Nadeau C, Oballa RM, Ouellet SG, Powell DA, Ramtohul YK, Tranmer GK, Trinh T, Wang H, Zhang L.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):980-4. doi: 10.1016/j.bmcl.2011.12.002. Epub 2011 Dec 8.

PMID:
22209206
38.

Magnetoelastic metamaterials.

Lapine M, Shadrivov IV, Powell DA, Kivshar YS.

Nat Mater. 2011 Nov 13;11(1):30-3. doi: 10.1038/nmat3168.

PMID:
22081080
39.

Nicotinic acids: liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy.

Powell DA, Black WC, Bleasby K, Chan CC, Deschenes D, Gagnon M, Gordon R, Guay J, Guiral S, Hafey MJ, Huang Z, Isabel E, Leblanc Y, Styhler A, Xu LJ, Zhang L, Oballa RM.

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7281-6. doi: 10.1016/j.bmcl.2011.10.040. Epub 2011 Oct 18.

PMID:
22047692
40.

Oral acyclovir suppression and neurodevelopment after neonatal herpes.

Kimberlin DW, Whitley RJ, Wan W, Powell DA, Storch G, Ahmed A, Palmer A, Sánchez PJ, Jacobs RF, Bradley JS, Robinson JL, Shelton M, Dennehy PH, Leach C, Rathore M, Abughali N, Wright P, Frenkel LM, Brady RC, Van Dyke R, Weiner LB, Guzman-Cottrill J, McCarthy CA, Griffin J, Jester P, Parker M, Lakeman FD, Kuo H, Lee CH, Cloud GA; National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group.

N Engl J Med. 2011 Oct 6;365(14):1284-92. doi: 10.1056/NEJMoa1003509.

41.

Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.

Oballa RM, Belair L, Black WC, Bleasby K, Chan CC, Desroches C, Du X, Gordon R, Guay J, Guiral S, Hafey MJ, Hamelin E, Huang Z, Kennedy B, Lachance N, Landry F, Li CS, Mancini J, Normandin D, Pocai A, Powell DA, Ramtohul YK, Skorey K, Sørensen D, Sturkenboom W, Styhler A, Waddleton DM, Wang H, Wong S, Xu L, Zhang L.

J Med Chem. 2011 Jul 28;54(14):5082-96. doi: 10.1021/jm200319u. Epub 2011 Jun 28.

PMID:
21661758
42.

Government management of two media-facilitated crises involving dioxin contamination of food.

Jacob CJ, Lok C, Morley K, Powell DA.

Public Underst Sci. 2011 Mar;20(2):261-9.

PMID:
21657135
43.

One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates.

Denton PW, Othieno F, Martinez-Torres F, Zou W, Krisko JF, Fleming E, Zein S, Powell DA, Wahl A, Kwak YT, Welch BD, Kay MS, Payne DA, Gallay P, Appella E, Estes JD, Lu M, Garcia JV.

J Virol. 2011 Aug;85(15):7582-93. doi: 10.1128/JVI.00537-11. Epub 2011 May 18.

44.

Observation-based evaluation of hand hygiene practices and the effects of an intervention at a public hospital cafeteria.

Filion K, Kukanich KS, Chapman B, Hardigree MK, Powell DA.

Am J Infect Control. 2011 Aug;39(6):464-70. doi: 10.1016/j.ajic.2010.09.016. Epub 2011 May 12.

45.

High-throughput scintillation proximity assay for stearoyl-CoA desaturase-1.

Tawa P, Falgueyret JP, Guiral S, Isabel E, Powell DA, Zuck P, Skorey K.

J Biomol Screen. 2011 Jun;16(5):506-17. doi: 10.1177/1087057111399436. Epub 2011 Mar 15.

PMID:
21406617
46.

Deformations and end effects in isolated blood vessel testing.

Monson KL, Mathur V, Powell DA.

J Biomech Eng. 2011 Jan;133(1):011005. doi: 10.1115/1.4002935.

PMID:
21186895
47.

Biological activity and preclinical efficacy of azetidinyl pyridazines as potent systemically-distributed stearoyl-CoA desaturase inhibitors.

Isabel E, Powell DA, Black WC, Chan CC, Crane S, Gordon R, Guay J, Guiral S, Huang Z, Robichaud J, Skorey K, Tawa P, Xu L, Zhang L, Oballa R.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):479-83. doi: 10.1016/j.bmcl.2010.10.107. Epub 2010 Oct 26.

PMID:
21074991
48.

2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors.

Powell DA, Ramtohul Y, Lebrun ME, Oballa R, Bhat S, Falgueyret JP, Guiral S, Huang Z, Skorey K, Tawa P, Zhang L.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6366-9. doi: 10.1016/j.bmcl.2010.09.094. Epub 2010 Sep 19.

PMID:
20933412
49.

Immunizations for internationally adopted children.

Spicer KB, Powell DA.

Pediatr Ann. 2010 Aug;39(8):517-20, 523-4. doi: 10.3928/00904481-20100726-10. Review. No abstract available.

PMID:
20704148
50.

This issue: vaccines: addressing the challenges of immunizing our children.

Powell DA.

Pediatr Ann. 2010 Aug;39(8):464-6. doi: 10.3928/00904481-20100726-02. No abstract available.

PMID:
20704140

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