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Items: 15


Blackboard to Bedside: A Mathematical Modeling Bottom-Up Approach Toward Personalized Cancer Treatments.

Hamis S, Powathil GG, Chaplain MAJ.

JCO Clin Cancer Inform. 2019 Feb;3:1-11. doi: 10.1200/CCI.18.00068.


The tubercular badger and the uncertain curve:- The need for a multiple stressor approach in environmental radiation protection.

Mothersill C, Abend M, Bréchignac F, Copplestone D, Geras'kin S, Goodman J, Horemans N, Jeggo P, McBride W, Mousseau TA, O'Hare A, Papineni RVL, Powathil G, Schofield PN, Seymour C, Sutcliffe J, Austin B.

Environ Res. 2019 Jan;168:130-140. doi: 10.1016/j.envres.2018.09.031. Epub 2018 Sep 26. Review.


Role of extracellular matrix and microenvironment in regulation of tumor growth and LAR-mediated invasion in glioblastoma.

Kim Y, Kang H, Powathil G, Kim H, Trucu D, Lee W, Lawler S, Chaplain M.

PLoS One. 2018 Oct 4;13(10):e0204865. doi: 10.1371/journal.pone.0204865. eCollection 2018.


What does not kill a tumour may make it stronger: In silico insights into chemotherapeutic drug resistance.

Hamis S, Nithiarasu P, Powathil GG.

J Theor Biol. 2018 Oct 7;454:253-267. doi: 10.1016/j.jtbi.2018.06.014. Epub 2018 Jun 15.


Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment: Insights from a hybrid multiscale cellular automaton model.

Bowness R, Chaplain MAJ, Powathil GG, Gillespie SH.

J Theor Biol. 2018 Jun 7;446:87-100. doi: 10.1016/j.jtbi.2018.03.006. Epub 2018 Mar 7.


When a duck is not a duck; a new interdisciplinary synthesis for environmental radiation protection.

Mothersill C, Abend M, Bréchignac F, Iliakis G, Impens N, Kadhim M, Møller AP, Oughton D, Powathil G, Saenen E, Seymour C, Sutcliffe J, Tang FR, Schofield PN.

Environ Res. 2018 Apr;162:318-324. doi: 10.1016/j.envres.2018.01.022. Epub 2018 Feb 4.


Combining radiation with hyperthermia: a multiscale model informed by in vitro experiments.

Brüningk S, Powathil G, Ziegenhein P, Ijaz J, Rivens I, Nill S, Chaplain M, Oelfke U, Ter Haar G.

J R Soc Interface. 2018 Jan;15(138). pii: 20170681. doi: 10.1098/rsif.2017.0681.


Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma.

Borasi G, Nahum A, Paulides MM, Powathil G, Russo G, Fariselli L, Lamia D, Cirincione R, Forte GI, Borrazzo C, Caccia B, di Castro E, Pozzi S, Gilardi MC.

J Ther Ultrasound. 2016 Dec 8;4:32. eCollection 2016.


Bystander effects and their implications for clinical radiation therapy: Insights from multiscale in silico experiments.

Powathil GG, Munro AJ, Chaplain MA, Swat M.

J Theor Biol. 2016 Jul 21;401:1-14. doi: 10.1016/j.jtbi.2016.04.010. Epub 2016 Apr 12.


Strategies of eradicating glioma cells: a multi-scale mathematical model with MiR-451-AMPK-mTOR control.

Kim Y, Powathil G, Kang H, Trucu D, Kim H, Lawler S, Chaplain M.

PLoS One. 2015 Jan 28;10(1):e0114370. doi: 10.1371/journal.pone.0114370. eCollection 2015.


Systems oncology: towards patient-specific treatment regimes informed by multiscale mathematical modelling.

Powathil GG, Swat M, Chaplain MA.

Semin Cancer Biol. 2015 Feb;30:13-20. doi: 10.1016/j.semcancer.2014.02.003. Epub 2014 Mar 4. Review.


Towards predicting the response of a solid tumour to chemotherapy and radiotherapy treatments: clinical insights from a computational model.

Powathil GG, Adamson DJ, Chaplain MA.

PLoS Comput Biol. 2013;9(7):e1003120. doi: 10.1371/journal.pcbi.1003120. Epub 2013 Jul 11.


Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model.

Powathil GG, Gordon KE, Hill LA, Chaplain MA.

J Theor Biol. 2012 Sep 7;308:1-19. doi: 10.1016/j.jtbi.2012.05.015. Epub 2012 May 29.


Modeling the spatial distribution of chronic tumor hypoxia: implications for experimental and clinical studies.

Powathil G, Kohandel M, Milosevic M, Sivaloganathan S.

Comput Math Methods Med. 2012;2012:410602. doi: 10.1155/2012/410602. Epub 2012 Jan 29.


Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy.

Powathil G, Kohandel M, Sivaloganathan S, Oza A, Milosevic M.

Phys Med Biol. 2007 Jun 7;52(11):3291-306. Epub 2007 May 15.


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