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Items: 1 to 50 of 115

1.

PON1 increases cellular DNA damage by lactone substrates.

Shangula S, Noori M, Ahmad I, Margison GP, Liu Y, Siahmansur T, Soran H, Povey AC.

Arch Toxicol. 2019 Jul;93(7):2035-2043. doi: 10.1007/s00204-019-02475-w. Epub 2019 Jun 17.

PMID:
31209508
2.

Biomarkers of exposure in environment-wide association studies - Opportunities to decode the exposome using human biomonitoring data.

Steckling N, Gotti A, Bose-O'Reilly S, Chapizanis D, Costopoulou D, De Vocht F, Garí M, Grimalt JO, Heath E, Hiscock R, Jagodic M, Karakitsios SP, Kedikoglou K, Kosjek T, Leondiadis L, Maggos T, Mazej D, Polańska K, Povey A, Rovira J, Schoierer J, Schuhmacher M, Špirić Z, Stajnko A, Stierum R, Tratnik JS, Vassiliadou I, Annesi-Maesano I, Horvat M, Sarigiannis DA.

Environ Res. 2018 Jul;164:597-624. doi: 10.1016/j.envres.2018.02.041. Epub 2018 Apr 5. Review.

3.

L-β-N-methylamino-l-alanine (BMAA) nitrosation generates a cytotoxic DNA damaging alkylating agent: An unexplored mechanism for neurodegenerative disease.

Potjewyd G, Day PJ, Shangula S, Margison GP, Povey AC.

Neurotoxicology. 2017 Mar;59:105-109. doi: 10.1016/j.neuro.2017.01.007. Epub 2017 Feb 3.

PMID:
28163087
4.

Silver nanoparticles exhibit size-dependent differential toxicity and induce expression of syncytin-1 in FA-AML1 and MOLT-4 leukaemia cell lines.

Alqahtani S, Promtong P, Oliver AW, He XT, Walker TD, Povey A, Hampson L, Hampson IN.

Mutagenesis. 2016 Nov;31(6):695-702. Epub 2016 Aug 30.

PMID:
27576335
5.

Cytotoxicity and genotoxicity of urban particulate matter in mammalian cells.

Dumax-Vorzet AF, Tate M, Walmsley R, Elder RH, Povey AC.

Mutagenesis. 2015 Sep;30(5):621-33. doi: 10.1093/mutage/gev025. Epub 2015 Jun 25.

6.

Pesticide exposure and screen-positive neuropsychiatric disease in British sheep farmers.

Povey AC, McNamee R, Alhamwi H, Stocks SJ, Watkins G, Burns A, Agius R.

Environ Res. 2014 Nov;135:262-70. doi: 10.1016/j.envres.2014.09.008. Epub 2014 Oct 14.

PMID:
25462674
7.

Increased N7-methyldeoxyguanosine DNA adducts after occupational exposure to pesticides and influence of genetic polymorphisms of paraoxonase-1 and glutathione S-transferase M1 and T1.

Gómez-Martín A, Altakroni B, Lozano-Paniagua D, Margison GP, de Vocht F, Povey AC, Hernández AF.

Environ Mol Mutagen. 2015 Jun;56(5):437-45. doi: 10.1002/em.21929. Epub 2014 Nov 26.

PMID:
25427726
8.

Pesticide residue transfer in Thai farmer families: using structural equation modeling to determine exposure pathways.

Liu H, Hanchenlaksh C, Povey AC, de Vocht F.

Environ Sci Technol. 2015 Jan 6;49(1):562-9. doi: 10.1021/es503875t. Epub 2014 Dec 12.

PMID:
25407029
9.

The mediation of social influences on smoking cessation and awareness of the early signs of lung cancer.

Chatwin J, Povey A, Kennedy A, Frank T, Firth A, Booton R, Barber P, Sanders C.

BMC Public Health. 2014 Oct 7;14:1043. doi: 10.1186/1471-2458-14-1043.

10.

Modifiable and non-modifiable risk factors for poor sperm morphology.

Pacey AA, Povey AC, Clyma JA, McNamee R, Moore HD, Baillie H, Cherry NM; Participating Centres of Chaps-UK.

Hum Reprod. 2014 Aug;29(8):1629-36. doi: 10.1093/humrep/deu116. Epub 2014 Jun 4.

PMID:
24899128
11.

How potentially serious symptom changes are talked about and managed in COPD clinical review consultations: a micro-analysis.

Chatwin J, Kennedy A, Firth A, Povey A, Rogers A, Sanders C.

Soc Sci Med. 2014 Jul;113:120-36. doi: 10.1016/j.socscimed.2014.04.048. Epub 2014 May 9.

PMID:
24861413
12.

Occupation exposures and sperm morphology: a case-referent analysis of a multi-centre study.

Cherry N, Povey AC, McNamee R, Moore H, Baillie H, Clyma JA, Dippnall M, Pacey AA; participating centres of CHAPS-UK.

Occup Environ Med. 2014 Sep;71(9):598-604. doi: 10.1136/oemed-2013-101996. Epub 2014 May 20.

PMID:
24847137
13.

Personal exposure to inhalable dust and the specific latex aero-allergen, Hev b6.02, in latex glove manufacturing in Thailand.

Sanguanchaiyakrit N, Povey AC, de Vocht F.

Ann Occup Hyg. 2014 Jun;58(5):542-50. doi: 10.1093/annhyg/meu013. Epub 2014 Feb 25. Erratum in: Ann Occup Hyg. 2014 Aug;58(7):931.

14.

Latex sensitization and risk factors in female nurses in Thai governmental hospitals.

Supapvanich C, Povey AC, De Vocht F.

Int J Occup Med Environ Health. 2014 Jan;27(1):93-103. doi: 10.2478/s13382-014-0230-7.

15.
16.

Bayesian inference supports a location and neighbour-dependent model of DNA methylation propagation at the MGMT gene promoter in lung tumours.

Bonello N, Sampson J, Burn J, Wilson IJ, McGrown G, Margison GP, Thorncroft M, Crossbie P, Povey AC, Santibanez-Koref M, Walters K.

J Theor Biol. 2013 Nov 7;336:87-95. doi: 10.1016/j.jtbi.2013.07.019. Epub 2013 Jul 30.

PMID:
23911575
17.

Chlorination by-products in tap water and semen quality in England and Wales.

Iszatt N, Nieuwenhuijsen MJ, Bennett J, Best N, Povey AC, Pacey AA, Moore H, Cherry N, Toledano MB.

Occup Environ Med. 2013 Nov;70(11):754-60. doi: 10.1136/oemed-2012-101339. Epub 2013 Jun 12.

PMID:
23759536
18.

Respiratory and dermal symptoms in Thai nurses using latex products.

Supapvanich C, Povey AC, de Vocht F.

Occup Med (Lond). 2013 Sep;63(6):425-8. doi: 10.1093/occmed/kqt068. Epub 2013 Jun 7.

PMID:
23749805
19.

Topographical study of O(6)-alkylguanine DNA alkyltransferase repair activity and N7-methylguanine levels in resected lung tissue.

Crosbie PA, Harrison K, Shah R, Watson AJ, Agius R, Barber PV, Margison GP, Povey AC.

Chem Biol Interact. 2013 Jul 5;204(2):98-104. doi: 10.1016/j.cbi.2013.04.013. Epub 2013 May 9.

PMID:
23665414
20.

The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase.

Senthong P, Millington CL, Wilkinson OJ, Marriott AS, Watson AJ, Reamtong O, Eyers CE, Williams DM, Margison GP, Povey AC.

Nucleic Acids Res. 2013 Mar 1;41(5):3047-55. doi: 10.1093/nar/gks1476. Epub 2013 Jan 17.

21.

Synthesis of oligodeoxyribonucleotides containing a conformationally-locked anti analogue of O6-methyl-2'-deoxyguanosine and their recognition by MGMT and Atl1.

Abdu K, Aiertza MK, Wilkinson OJ, Grasby JA, Senthong P, Povey AC, Margison GP, Williams DM.

Chem Commun (Camb). 2012 Nov 25;48(91):11214-6. doi: 10.1039/c2cc36252j. Epub 2012 Oct 11.

PMID:
23059787
22.

Estimation of a lidar's overlap function and its calibration by nonlinear regression.

Povey AC, Grainger RG, Peters DM, Agnew JL, Rees D.

Appl Opt. 2012 Jul 20;51(21):5130-43. doi: 10.1364/AO.51.005130.

PMID:
22858954
23.

Acute ill-health in sheep farmers following use of pesticides.

Povey AC, Rees HG, Thompson JP, Watkins G, Stocks SJ, Karalliedde L.

Occup Med (Lond). 2012 Oct;62(7):541-8. doi: 10.1093/occmed/kqs099. Epub 2012 Jul 5.

PMID:
22773656
24.

Modifiable and non-modifiable risk factors for poor semen quality: a case-referent study.

Povey AC, Clyma JA, McNamee R, Moore HD, Baillie H, Pacey AA, Cherry NM; Participating Centres of Chaps-uk.

Hum Reprod. 2012 Sep;27(9):2799-806. doi: 10.1093/humrep/des183. Epub 2012 Jun 12.

PMID:
22695289
25.

Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.

Latypov VF, Tubbs JL, Watson AJ, Marriott AS, McGown G, Thorncroft M, Wilkinson OJ, Senthong P, Butt A, Arvai AS, Millington CL, Povey AC, Williams DM, Santibanez-Koref MF, Tainer JA, Margison GP.

Mol Cell. 2012 Jul 13;47(1):50-60. doi: 10.1016/j.molcel.2012.04.028. Epub 2012 May 31.

26.

Convenient and efficient syntheses of oligodeoxyribonucleotides containing O(6)-(carboxymethyl)guanine and O(6)-(4-oxo-4-(3-pyridyl)butyl)guanine.

Millington CL, Watson AJ, Marriott AS, Margison GP, Povey AC, Williams DM.

Nucleosides Nucleotides Nucleic Acids. 2012 Apr;31(4):328-38. doi: 10.1080/15257770.2012.656784.

PMID:
22444194
27.

Elevated N3-methylpurine-DNA glycosylase DNA repair activity is associated with lung cancer.

Crosbie PA, Watson AJ, Agius R, Barber PV, Margison GP, Povey AC.

Mutat Res. 2012 Apr 1;732(1-2):43-6. doi: 10.1016/j.mrfmmm.2012.01.001. Epub 2012 Jan 14.

PMID:
22266085
28.

Urinary DAP metabolite levels in Thai farmers and their families and exposure to pesticides from agricultural pesticide spraying.

Hanchenlaksh C, Povey A, O'Brien S, de Vocht F.

Occup Environ Med. 2011 Aug;68(8):625-7. doi: 10.1136/oem.2010.060897. Epub 2011 Mar 12.

PMID:
21398679
29.

Environmental and occupational toxicants.

de Vocht F, Vlaanderen J, Povey AC, Balbo S, Vermeulen R.

IARC Sci Publ. 2011;(163):163-74. Review.

PMID:
22997861
30.

Epidemiology and trends in male subfertility.

Povey AC, Stocks SJ.

Hum Fertil (Camb). 2010 Dec;13(4):182-8. doi: 10.3109/14647273.2010.515700. Review.

PMID:
21117926
31.

Expression of O-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients.

Saad AA, Kassem HSh, Povey AC, Margison GP.

J Nucleic Acids. 2010 Oct 17;2010:840230. doi: 10.4061/2010/840230.

32.

'Dippers' flu' and its relationship to PON1 polymorphisms.

Cherry N, Mackness M, Mackness B, Dippnall M, Povey A.

Occup Environ Med. 2011 Mar;68(3):211-7. doi: 10.1136/oem.2009.052126. Epub 2010 Oct 4.

PMID:
20921272
33.

Alkylation of sperm DNA is associated with male factor infertility and a reduction in the proportion of oocytes fertilised during assisted reproduction.

Stocks SJ, Agius RM, Cooley N, Harrison KL, Brison DR, Horne G, Gibbs A, Povey AC.

Mutat Res. 2010 Apr 30;698(1-2):18-23. doi: 10.1016/j.mrgentox.2010.02.019. Epub 2010 Mar 20.

PMID:
20307685
34.

Gene-environmental interactions and organophosphate toxicity.

Povey AC.

Toxicology. 2010 Dec 30;278(3):294-304. doi: 10.1016/j.tox.2010.02.007. Epub 2010 Feb 13. Review.

PMID:
20156521
35.

The effect of Msh2 knockdown on methylating agent induced toxicity in DNA glycosylase deficient cells.

Cooley N, Elder RH, Povey AC.

Toxicology. 2010 Jan 31;268(1-2):111-7. doi: 10.1016/j.tox.2009.12.008. Epub 2009 Dec 16.

PMID:
20025921
36.

Estimating intervention effects in a complex multi-level smoking prevention study.

Falcaro M, Povey AC, Fielder A, Nahit E, Pickles A.

Int J Environ Res Public Health. 2009 Feb;6(2):463-77. doi: 10.3390/ijerph6020463. Epub 2009 Feb 3.

37.

GSTM1 copy number and lung cancer risk.

Crosbie PA, Barber PV, Harrison KL, Gibbs AR, Agius RM, Margison GP, Povey AC.

Mutat Res. 2009 May 12;664(1-2):1-5. doi: 10.1016/j.mrfmmm.2009.01.006. Epub 2009 Feb 4.

PMID:
19428374
38.

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.

Cote ML, Chen W, Smith DW, Benhamou S, Bouchardy C, Butkiewicz D, Fong KM, Gené M, Hirvonen A, Kiyohara C, Larsen JE, Lin P, Raaschou-Nielsen O, Povey AC, Reszka E, Risch A, Schneider J, Schwartz AG, Sorensen M, To-Figueras J, Tokudome S, Pu Y, Yang P, Wenzlaff AS, Wikman H, Taioli E.

Am J Epidemiol. 2009 Apr 1;169(7):802-14. doi: 10.1093/aje/kwn417. Epub 2009 Feb 24.

39.

Dietary variables associated with DNA N7-methylguanine levels and O6-alkylguanine DNA-alkyltransferase activity in human colorectal mucosa.

Billson HA, Harrison KL, Lees NP, Hall CN, Margison GP, Povey AC.

Carcinogenesis. 2009 Apr;30(4):615-20. doi: 10.1093/carcin/bgp020. Epub 2009 Jan 23.

PMID:
19168588
40.

Occupation and male infertility: glycol ethers and other exposures.

Cherry N, Moore H, McNamee R, Pacey A, Burgess G, Clyma JA, Dippnall M, Baillie H, Povey A; participating centres of Chaps-UK.

Occup Environ Med. 2008 Oct;65(10):708-14. doi: 10.1136/oem.2007.035824. Epub 2008 Apr 16.

PMID:
18417551
41.

Association between lung cancer risk and single nucleotide polymorphisms in the first intron and codon 178 of the DNA repair gene, O6-alkylguanine-DNA alkyltransferase.

Crosbie PA, McGown G, Thorncroft MR, O'Donnell PN, Barber PV, Lewis SJ, Harrison KL, Agius RM, Santibáñez-Koref MF, Margison GP, Povey AC.

Int J Cancer. 2008 Feb 15;122(4):791-5.

42.

Lung cancer risk and variation in MGMT activity and sequence.

Povey AC, Margison GP, Santibáñez-Koref MF.

DNA Repair (Amst). 2007 Aug 1;6(8):1134-44. Epub 2007 Jun 13. Review.

PMID:
17569600
43.

GST CYP and PON1 polymorphisms in farmers attributing ill health to organophosphate-containing sheep dip.

Povey AC, Jury F, Dippnall WM, Smith AE, Thomson S, Mackness B, Mackness M, Durrington P, Cherry NM.

Biomarkers. 2007 Mar-Apr;12(2):188-202.

PMID:
17536768
44.

Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review.

Kellen E, Hemelt M, Broberg K, Golka K, Kristensen VN, Hung RJ, Matullo G, Mittal RD, Porru S, Povey A, Schulz WA, Shen J, Buntinx F, Zeegers MP, Taioli E.

Am J Epidemiol. 2007 Jun 1;165(11):1221-30. Epub 2007 Apr 2. Review.

PMID:
17404387
45.

Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review.

Raimondi S, Paracchini V, Autrup H, Barros-Dios JM, Benhamou S, Boffetta P, Cote ML, Dialyna IA, Dolzan V, Filiberti R, Garte S, Hirvonen A, Husgafvel-Pursiainen K, Imyanitov EN, Kalina I, Kang D, Kiyohara C, Kohno T, Kremers P, Lan Q, London S, Povey AC, Rannug A, Reszka E, Risch A, Romkes M, Schneider J, Seow A, Shields PG, Sobti RC, Sørensen M, Spinola M, Spitz MR, Strange RC, Stücker I, Sugimura H, To-Figueras J, Tokudome S, Yang P, Yuan JM, Warholm M, Taioli E.

Am J Epidemiol. 2006 Dec 1;164(11):1027-42. Epub 2006 Sep 25.

PMID:
17000715
46.
47.

No association between N7-methyldeoxyguanosine and 8-oxodeoxyguanosine levels in human lymphocyte DNA.

Harrison KL, Crosbie PA, Agius RM, Barber PV, Carus M, Margison GP, Povey AC.

Mutat Res. 2006 Aug 30;600(1-2):125-30. Epub 2006 Jun 12.

PMID:
16765387
48.

Bladder tumor contains higher N7-methylguanine levels in DNA than adjacent normal bladder epithelium.

Saad AA, O'Connor PJ, Mostafa MH, Metwalli NE, Cooper DP, Margison GP, Povey AC.

Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):740-3.

49.

N7-methyldeoxyguanosine levels in DNA isolated from cervical cytology samples are associated with smoking.

Harrison KL, Khan NS, Dey P, Povey AC.

Int J Cancer. 2006 Aug 15;119(4):961-3.

50.

Smoking is associated with a decrease of O6-alkylguanine-DNA alkyltransferase activity in bronchial epithelial cells.

Povey AC, O'Donnell P, Barber P, Watson M, Margison GP, Santibáñez Koref MF.

Int J Cancer. 2006 Jul 15;119(2):463-6.

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